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Volumn 29, Issue 3, 2004, Pages 208-218

Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: Relevance to the antidepressant/anxiolytic response

Author keywords

Antidepressive agents; Depression; Norepinephrine; Receptors, adrenergic; Receptors, neurokinin 1; Serotonin; Substance P

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; 2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 5 [[2 [1 [3,5 BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY] 3 (4 FLUOROPHENYL) 4 MORPHOLINYL]METHYL] N,N DIMETHYL 1H 1,2,3 TRIAZOLE 4 METHANAMINE; APREPITANT; CLONIDINE; MIRTAZAPINE; NORADRENALIN; RP 68750; SEROTONIN; SUBSTANCE P ANTAGONIST; TACHYKININ RECEPTOR ANTAGONIST; TETRODOTOXIN; UNCLASSIFIED DRUG; VOFOPITANT;

EID: 3042611638     PISSN: 11804882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (67)

References (39)
  • 1
    • 0035111499 scopus 로고    scopus 로고
    • Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors
    • Thase ME, Entsuah AR, Rudolph RL. Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry 2001;178:234-41.
    • (2001) Br J Psychiatry , vol.178 , pp. 234-241
    • Thase, M.E.1    Entsuah, A.R.2    Rudolph, R.L.3
  • 2
    • 34547462653 scopus 로고    scopus 로고
    • New goals in the treatment of depression: Moving toward recovery
    • Thase ME, Ninan PT. New goals in the treatment of depression: moving toward recovery. Psychopharmacol Bull 2002;36(Suppl 2):24-35.
    • (2002) Psychopharmacol Bull , vol.36 , Issue.2 SUPPL. , pp. 24-35
    • Thase, M.E.1    Ninan, P.T.2
  • 3
    • 0032508514 scopus 로고    scopus 로고
    • Distinct mechanism for antidepressant activity by blockade of central substance P receptors
    • Kramer MS, Cutler N, Feighner J, Shrivastava R, Carman J, Sramek JJ, et al. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 1998;281:1640-5.
    • (1998) Science , vol.281 , pp. 1640-1645
    • Kramer, M.S.1    Cutler, N.2    Feighner, J.3    Shrivastava, R.4    Carman, J.5    Sramek, J.J.6
  • 4
    • 0017698253 scopus 로고
    • Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides
    • Guyenet PG, Aghajanian GK. Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides. Brain Res 1977;136:178-84.
    • (1977) Brain Res , vol.136 , pp. 178-184
    • Guyenet, P.G.1    Aghajanian, G.K.2
  • 5
    • 0026030492 scopus 로고
    • Activity and distribution of binding sites in brain of a nonpeptide substance P (NK1) receptor antagonist
    • McLean S, Ganong AH, Seeger TF, Bryce DK, Pratt KG, Reynolds LS, et al. Activity and distribution of binding sites in brain of a nonpeptide substance P (NK1) receptor antagonist. Science 1991;251:437-9.
    • (1991) Science , vol.251 , pp. 437-439
    • McLean, S.1    Ganong, A.H.2    Seeger, T.F.3    Bryce, D.K.4    Pratt, K.G.5    Reynolds, L.S.6
  • 6
    • 17644433355 scopus 로고    scopus 로고
    • Serotonin and substance P co-exist in dorsal raphe neurons of the human brain
    • Sergeyev V, Hokfelt T, Hurd Y. Serotonin and substance P co-exist in dorsal raphe neurons of the human brain. Neuroreport 1999;10:3967-70.
    • (1999) Neuroreport , vol.10 , pp. 3967-3970
    • Sergeyev, V.1    Hokfelt, T.2    Hurd, Y.3
  • 7
    • 0030580383 scopus 로고    scopus 로고
    • Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat
    • Shirayama Y, Mitsushio H, Takashima M, Ichikawa H, Takahashi K. Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat. Brain Res 1996;739:70-8.
    • (1996) Brain Res , vol.739 , pp. 70-78
    • Shirayama, Y.1    Mitsushio, H.2    Takashima, M.3    Ichikawa, H.4    Takahashi, K.5
  • 8
    • 0035856882 scopus 로고    scopus 로고
    • Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons
    • Szabo ST, Blier P. Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons. Brain Res 2001;922:9-20.
    • (2001) Brain Res , vol.922 , pp. 9-20
    • Szabo, S.T.1    Blier, P.2
  • 9
    • 0034604784 scopus 로고    scopus 로고
    • Noradrenergic neurons expressing substance P receptor (NK1) in the locus coeruleus complex: A double immunofluoresence study in the rat
    • Chen LW, Wei LC, Liu HL, Rao ZR. Noradrenergic neurons expressing substance P receptor (NK1) in the locus coeruleus complex: a double immunofluoresence study in the rat. Brain Res 2000;873:155-9.
    • (2000) Brain Res , vol.873 , pp. 155-159
    • Chen, L.W.1    Wei, L.C.2    Liu, H.L.3    Rao, Z.R.4
  • 10
    • 0035852719 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function
    • Santarelli L, Gobbi G, Debs PC, Sibille ET, Blier P, Hen R, et al. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proc Natl Acad Sci U S A 2001;98:1912-7.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1912-1917
    • Santarelli, L.1    Gobbi, G.2    Debs, P.C.3    Sibille, E.T.4    Blier, P.5    Hen, R.6
  • 11
    • 0036710083 scopus 로고    scopus 로고
    • Neurokinins activate local glutamatergic inputs to serotonergic neurons of the dorsal raphe nucleus
    • Liu R, Ding Y, Aghajanian GK. Neurokinins activate local glutamatergic inputs to serotonergic neurons of the dorsal raphe nucleus. Neuropsychopharmacology 2002;27:329-40.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 329-340
    • Liu, R.1    Ding, Y.2    Aghajanian, G.K.3
  • 12
    • 0034719969 scopus 로고    scopus 로고
    • Effect of neurokinin-1 receptor antagonists on the function of 5-HT and noradrenaline neurons
    • Haddjeri N, Blier P. Effect of neurokinin-1 receptor antagonists on the function of 5-HT and noradrenaline neurons. Neuroreport 2000;11:1323-7.
    • (2000) Neuroreport , vol.11 , pp. 1323-1327
    • Haddjeri, N.1    Blier, P.2
  • 13
    • 3042529176 scopus 로고    scopus 로고
    • Effects of neurokinin 1 antagonists on the firing of locus coeruleus norepinephrine neurons
    • Haddjeri N, Blier P. Effects of neurokinin 1 antagonists on the firing of locus coeruleus norepinephrine neurons. Abstr Soc Neurosci 2001;31:749.
    • (2001) Abstr Soc Neurosci , vol.31 , pp. 749
    • Haddjeri, N.1    Blier, P.2
  • 14
    • 0037074949 scopus 로고    scopus 로고
    • Chronic substance P (NK1) receptor antagonist and convention: Antidepressant treatment increases burst firing of monoamine neurons in the locus coeruleus
    • Maubach KA, Martin K, Chicchi G, Harrison T, Wheeldon A, Swain CJ, et al. Chronic substance P (NK1) receptor antagonist and convention: antidepressant treatment increases burst firing of monoamine neurons in the locus coeruleus. Neuroscience 2002;109:609-17.
    • (2002) Neuroscience , vol.109 , pp. 609-617
    • Maubach, K.A.1    Martin, K.2    Chicchi, G.3    Harrison, T.4    Wheeldon, A.5    Swain, C.J.6
  • 15
    • 3042670934 scopus 로고    scopus 로고
    • Neurokinin 1 (NK1), serotonin (5-HT) and norepinephrine (NE) receptors interactions: In vivo electrophysiological evidence
    • Gobbi G, Santarelli L, Hen R, Blier P. Neurokinin 1 (NK1), serotonin (5-HT) and norepinephrine (NE) receptors interactions: in vivo electrophysiological evidence. Abstr Soc Neurosci 2001;31:239.
    • (2001) Abstr Soc Neurosci , vol.31 , pp. 239
    • Gobbi, G.1    Santarelli, L.2    Hen, R.3    Blier, P.4
  • 16
    • 0036132430 scopus 로고    scopus 로고
    • Permissive role of neurokinin NK(3) receptors in NK(1) receptor-mediated activation of the locus coeruleus revealed by SR 142801
    • Bert L, Rodier D, Bougault I, Allouard N, Le Fur G, Soubrie P, et al. Permissive role of neurokinin NK(3) receptors in NK(1) receptor-mediated activation of the locus coeruleus revealed by SR 142801. Synapse 2002;43:62-9.
    • (2002) Synapse , vol.43 , pp. 62-69
    • Bert, L.1    Rodier, D.2    Bougault, I.3    Allouard, N.4    Le Fur, G.5    Soubrie, P.6
  • 17
    • 0035107206 scopus 로고    scopus 로고
    • Selective blockade of neurokinin (NK)(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats
    • Millan MJ, Lejeune F, De Nanteuil G, Gobert A. Selective blockade of neurokinin (NK)(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats. J Neurochem 2001;76:1949-54.
    • (2001) J Neurochem , vol.76 , pp. 1949-1954
    • Millan, M.J.1    Lejeune, F.2    De Nanteuil, G.3    Gobert, A.4
  • 18
    • 0016593641 scopus 로고
    • Inhibition of both noradrenergic and serotonergic neurons in brain by the alpha-adrenergic agonist clonidine
    • Svensson TH, Bunney BS, Aghajanian GK. Inhibition of both noradrenergic and serotonergic neurons in brain by the alpha-adrenergic agonist clonidine. Brain Res 1975;92:291-306.
    • (1975) Brain Res , vol.92 , pp. 291-306
    • Svensson, T.H.1    Bunney, B.S.2    Aghajanian, G.K.3
  • 20
    • 0017744244 scopus 로고
    • Physiological evidence for habenula as major link between forebrain and midbrain raphe
    • Wang RY, Aghajanian GK. Physiological evidence for habenula as major link between forebrain and midbrain raphe. Science 1977;197:89-91.
    • (1977) Science , vol.197 , pp. 89-91
    • Wang, R.Y.1    Aghajanian, G.K.2
  • 21
    • 0022492090 scopus 로고
    • Evidence for, and nature of, the tonic inhibitory influence of habenulointerpeduncular pathways upon cerebral dopaminergic transmission in the rat
    • Nishikawa T, Fage D, Scatton B. Evidence for, and nature of, the tonic inhibitory influence of habenulointerpeduncular pathways upon cerebral dopaminergic transmission in the rat. Brain Res 1986;373:324-36.
    • (1986) Brain Res , vol.373 , pp. 324-336
    • Nishikawa, T.1    Fage, D.2    Scatton, B.3
  • 23
    • 0035887916 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization
    • Froger N, Gardier AM, Mratalla R, Alberti I, Lena I, Boni C, et al. 5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization. J Neurosci 2001;21:8188-97.
    • (2001) J Neurosci , vol.21 , pp. 8188-8197
    • Froger, N.1    Gardier, A.M.2    Mratalla, R.3    Alberti, I.4    Lena, I.5    Boni, C.6
  • 24
    • 0027508045 scopus 로고
    • 1A receptors in the dorsal raphe and hippocampus: I. Effect of spiperone
    • 1A receptors in the dorsal raphe and hippocampus: I. Effect of spiperone. J Pharmacol Exp Ther 1993;265:7-15.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 7-15
    • Blier, P.1    Lista, A.2    De Montigny, C.3
  • 26
    • 0035422889 scopus 로고    scopus 로고
    • Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission
    • Haddjeri N, Blier P. Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission. Biol Psychiatry 2001;50:191-9.
    • (2001) Biol Psychiatry , vol.50 , pp. 191-199
    • Haddjeri, N.1    Blier, P.2
  • 28
    • 0033953677 scopus 로고    scopus 로고
    • Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments
    • Haddjeri N, Szabo ST, de Montigny C, Blier P. Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments. Neuropsychopharmacology 2000;22:346-56.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 346-356
    • Haddjeri, N.1    Szabo, S.T.2    De Montigny, C.3    Blier, P.4
  • 30
    • 0023863123 scopus 로고
    • Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry
    • Gonon FG. Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry. Neuroscience 1988;24:19-28.
    • (1988) Neuroscience , vol.24 , pp. 19-28
    • Gonon, F.G.1
  • 31
    • 0342748363 scopus 로고    scopus 로고
    • Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons
    • Gartside SE, Hajos-Korcsok E, Bagdy E, Harsing LG Jr, Sharp T, Hajos M. Neurochemical and electrophysiological studies on the functional significance of burst firing in serotonergic neurons. Neuroscience 2000;98:295-300.
    • (2000) Neuroscience , vol.98 , pp. 295-300
    • Gartside, S.E.1    Hajos-Korcsok, E.2    Bagdy, E.3    Harsing Jr., L.G.4    Sharp, T.5    Hajos, M.6
  • 32
  • 33
    • 0032819493 scopus 로고    scopus 로고
    • Serotonin and drug-induced therapeutic responses in major depression, obsessive-compulsive and panic disorders
    • Blier P, de Montigny C. Serotonin and drug-induced therapeutic responses in major depression, obsessive-compulsive and panic disorders. Neuropsychopharmacology 1999;21(2 Suppl): 91S-98S.
    • (1999) Neuropsychopharmacology , vol.21 , Issue.2 SUPPL.
    • Blier, P.1    De Montigny, C.2
  • 34
    • 0030431697 scopus 로고
    • Effect of the alpha-2 adrenoceptor antagonist mirtazepine on the 5-hydroxytryptamine system in the rat brain
    • Haddjeri N, Blier P, de Montigny C. Effect of the alpha-2 adrenoceptor antagonist mirtazepine on the 5-hydroxytryptamine system in the rat brain. J Pharmacol Exp Ther 1966;277:861-71.
    • (1966) J Pharmacol Exp Ther , vol.277 , pp. 861-871
    • Haddjeri, N.1    Blier, P.2    De Montigny, C.3
  • 35
    • 0035068099 scopus 로고    scopus 로고
    • Modification of norepinephrine and serotonin, but not dopamine neuron firing by sustained bupropion treatment
    • Dong J, Blier P. Modification of norepinephrine and serotonin, but not dopamine neuron firing by sustained bupropion treatment. Psychopharmacology 2001;155:52-7.
    • (2001) Psychopharmacology , vol.155 , pp. 52-57
    • Dong, J.1    Blier, P.2
  • 36
    • 0037443873 scopus 로고    scopus 로고
    • Substance P serum levels are increased in major depression: Preliminary results
    • Bondy B, Baghai B, Minov C, Schule C, Schwarz MJ, Zwanzger P, et al. Substance P serum levels are increased in major depression: preliminary results. Biol Psychiatry 2003;15;53:538-42.
    • (2003) Biol Psychiatry , vol.15 , Issue.53 , pp. 538-542
    • Bondy, B.1    Baghai, B.2    Minov, C.3    Schule, C.4    Schwarz, M.J.5    Zwanzger, P.6
  • 38
    • 0030030571 scopus 로고    scopus 로고
    • Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression
    • Miller HL, Delgado PL, Salomon RM, Berman R, Krystal JH, Heninger GR, et al. Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression. Arch Gen Psychiatry 1996;53:117-28.
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 117-128
    • Miller, H.L.1    Delgado, P.L.2    Salomon, R.M.3    Berman, R.4    Krystal, J.H.5    Heninger, G.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.