Studies towards the next generation of antidepressants. Part 4: Derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 4, 2005, Pages 911-914

  Evrard, Deborah A ^a   Zhou, Ping ^a   Yi, Soo Y ^a   Zhou, Dahui ^a   Smith, Deborah L ^a   Sullivan, Kelly M ^a   Hornby, Geoffrey A ^a   Schechter, Lee E ^a   Andree, Terrance H ^a   Mewshaw, Richard E ^a  

^a PFIZER INC   (United States)

Author keywords

5 HT1A receptor antagonist; Antidepressant; Serotonin; SSRI

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ANTIDEPRESSANT AGENT; CYCLOHEXYLAMINE DERIVATIVE; ETHYLAMINE; PAROXETINE; PIPERAZINE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR;

AMINATION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; FEMALE; IC 50; NONHUMAN; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

EID: 20144389945     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.12.064     Document Type: Article

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