Synergism of 5-HT(1B/D) antagonists with paroxetine on serotonin efflux in rat ventral lateral geniculate nucleus slices

Brain Research Bulletin

Volumn 43, Issue 4, 1997, Pages 405-409

  Davidson, Colin ^a,b   Stamford, Jonathan A ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

5 HT(1B),5 HT(1D),5 HT uptake; Brain slice; Electrical stimulation; Fast cyclic voltammetry; Lateral geniculate nucleus; Serotonin (5 HT)

Indexed keywords

ISAMOLTANE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; PAROXETINE; SEROTONIN; SEROTONIN 1A ANTAGONIST; SEROTONIN 1B ANTAGONIST; SEROTONIN 1D ANTAGONIST; SEROTONIN UPTAKE INHIBITOR;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; ELECTROSTIMULATION; LATERAL GENICULATE NUCLEUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-ANXIETY AGENTS; DRUG SYNERGISM; GENICULATE BODIES; MALE; OXADIAZOLES; PAROXETINE; PIPERAZINES; PROPANOLAMINES; RATS; RATS, WISTAR; SEROTONIN;

EID: 0030843655     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(97)00026-9     Document Type: Article

References (31)

1. Adell A., Artigas F. Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytryptamine in raphe nuclei and frontal cortex. Naunyn Schmiedebergs Arch. Pharmacol. 343:1991;237-244.
2. Armstrong J. M., Millar J. Carbon fibre microelectrodes. J. Neurosci. Methods. 1:1979;279-287.
3. Artigas F., Perez V., Alvarez E. Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors. Arch. Gen. Psychiatry. 51:1994;248-251.
4. Asberg M., Erikkson B., Matensson B., Traskman-Bendz L., Wagner A. Therapeutic effects of serotonin uptake inhibitors in depression. J. Clin. Psychiatry. 47:1986;33-35.
5. Bel N., Artigas F. Fluvoxamine preferentially increases extracellular 5-hydroxytryptamine in the raphe nuclei: An in vivo microdialysis study. Eur. J. Pharmacol. 229:1992;101-103.
6. Blier P., De Montigny C. Current advances and trends in the treatment of depression. Trends Pharmacol. Sci. 15:1994;220-226.
7. Brauer K., Bruckner G., Leibnitz L., Werner L., Luth H. J., Winkelmann E. The ventral lateral geniculate nucleus of the albino rat: Morphological and histochemical observations. J. Hirnforsch. 25:1984;205-236.
8. 1B binding sites in rat brain. Naunyn Schmeidebergs Arch. Pharmacol. 347:1993;569-582.
9. Davidson C., Stamford J. A. Acute interaction of paroxetine and methiothepin on stimulated 5-hydroxytryptamine efflux in rat brain slices. Neuropsychopharmacology. 10:1994;6S.
10. Davidson C., Stamford J. A. Pindolol potentiates the effect of paroxetine on 5-HT efflux in the rat dorsal raphe nucleus. Eur. Neuropsychopharmacol. 5:1995;278.
11. 1B/D receptor antagonists. Neurosci. Lett. 188:1995;41-44.
12. 1A autoreceptors controlling 5-HT efflux and cell firing in the dorsal raphe nucleus. Br. J. Pharmacol. 119:1996;70P.
13. 1D autoreceptors. Neuropharmacology. 35:1996;1627-1634.
14. Davidson C., Stamford J. A. The effect of chronic paroxetine treatment on 5-HT terminal autoreceptors in the lateral geniculate nucleus. J. Psychopharmacol. 10:1996;A61.
15. 1B receptor in serotonergic neurons of anterior raphe nuclei in the rat brain. Synapse. 19:1995;18-25.
16. 1A receptor antagonist, WAY-100635. Eur. J. Pharmacol. 281:1995;81-88.
17. 1A receptor antagonist and SSRI in vivo: Effects on 5-HT cell firing and extracellular 5-HT. Br. J. Pharmacol. 115:1995;1064-1070.
18. 1D serotonin receptors in rat: Structural and pharmacological comparison of the two cloned receptors. Mol. Cell. Neurosci. 3:1992;578-587.
19. Hoyer D., Clarke D. E., Fozard J. R., Hartig P. R., Martin G. R., Mylecharane E. J., Saxena P. R., Humphrey P. P. A. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol. Rev. 46:1994;157-203.
20. Invernizzi R., Belli S., Samanin R. Citalopram's ability to increase the extracellular concentrations of serotonin in the dorsal raphe prevents the drug's effect in the frontal cortex. Brain Res. 584:1992;322-324.
21. 1D in the rabbit and guinea-pig brain cortex. Naunyn Schmeidebergs Arch. Pharmacol. 343:1991;352-364.
22. Meltzer H. Y., Lowy M. T. The serotonin hypothesis of depression. Meltzer H. Psychopharmacology: The third generation of progress. 1987;513-526 Raven Press, New York.
23. Moore R. Y., Card J. P. Intergeniculate leaflet - An anatomically and functionally distinct subdivision of the lateral geniculate complex. J. Comp. Neurol. 344:1994;403-430.
24. Moret C., Briley M. The unique effect of methiothepin on the terminal serotonin autoreceptor in the rat hypothalamus could be an example of inverse agonism. J. Psychopharmacol. 7:1993;331-337.
25. Moret C., Briley M. Serotonin autoreceptor subsensitivity and antidepressant activity. Eur. J. Pharmacol. 180:1990;351-356.
26. O'Connor J. J., Kruk Z. L. Fast cyclic voltammetry can be used to measure stimulated endogenous 5-hydroxytryptamine release in untreated rat brain slices. J. Neurosci. Methods. 38:1991;25-33.
27. Papadopoulos G. C., Parnevalas J. G. Distribution and synaptic organisation of serotoninergic and noradrenergic axons in the lateral geniculate nucleus of the rat. J. Comp. Neurol. 294:1990;345-355.
28. 1Dα receptor sites. Neuropharmacology. 34:1995;235-237.
29. 1B receptors. Naunyn Schmiedebergs Arch. Pharmacol. 353:1996;144-156.
30. Singer E. A. Transmitter release from brain slices elicited by single pulses: A powerful method to study presynaptic mechanisms. Trends. Pharmacol. Sci. 9:1988;274-276.
31. 1D receptor antagonist. Behav. Brain Res. 73:1996;157-161.