메뉴 건너뛰기




Volumn 3, Issue 3, 2007, Pages 156-165

Functional genomics of the oxidative stress pathway

Author keywords

Cardiovascular disease; Genomics; Glutathione S transferases; NADPH oxidase; Oxidative stress; Systems biology

Indexed keywords

ANTIOXIDANT; BIOLOGICAL MARKER; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE SYNTHASE; GLUTATHIONE TRANSFERASE M1; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

EID: 34547890304     PISSN: 15734021     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340207781386675     Document Type: Review
Times cited : (2)

References (145)
  • 1
    • 0030894162 scopus 로고    scopus 로고
    • Oxidative stress: Oxidants and antioxidants
    • Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol 1997; 82: 291-5.
    • (1997) Exp Physiol , vol.82 , pp. 291-295
    • Sies, H.1
  • 2
    • 25144453937 scopus 로고    scopus 로고
    • NADPH oxidase and endothetial cell function
    • Ray R, Shah AM. NADPH oxidase and endothetial cell function. Clin Sci (Lond) 2005; 109: 217-26.
    • (2005) Clin Sci (Lond) , vol.109 , pp. 217-226
    • Ray, R.1    Shah, A.M.2
  • 3
    • 33746804938 scopus 로고    scopus 로고
    • Reactive oxygen species in the cerebral circulation: Are they all bad?
    • Miller AA, Drummond GR, Sobey CG. Reactive oxygen species in the cerebral circulation: are they all bad? Antioxid Redox Signal 2006; 8:1113-20.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1113-1120
    • Miller, A.A.1    Drummond, G.R.2    Sobey, C.G.3
  • 4
    • 33745641665 scopus 로고    scopus 로고
    • Oxidative stress
    • Opara EC. Oxidative stress. Dis Mon 2006; 52: 183-98.
    • (2006) Dis Mon , vol.52 , pp. 183-198
    • Opara, E.C.1
  • 5
    • 4444329422 scopus 로고    scopus 로고
    • Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: What is the clinical significance?
    • Touyz RM. Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance? Hypertension 2004; 44: 248-52.
    • (2004) Hypertension , vol.44 , pp. 248-252
    • Touyz, R.M.1
  • 6
    • 0142055950 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS
    • Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS. Circulation 2003; 108: 1912-6.
    • (2003) Circulation , vol.108 , pp. 1912-1916
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 7
    • 0242349764 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part II: animal and human studies
    • Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 2003; 108: 2034-40.
    • (2003) Circulation , vol.108 , pp. 2034-2040
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 8
    • 1642386719 scopus 로고    scopus 로고
    • Strategies to reduce oxidative stress in cardiovascular disease
    • Hamilton CA, Miller WH, Al-Benna S, et al. Strategies to reduce oxidative stress in cardiovascular disease. Clin Sci (Lond) 2004; 106: 219-34.
    • (2004) Clin Sci (Lond) , vol.106 , pp. 219-234
    • Hamilton, C.A.1    Miller, W.H.2    Al-Benna, S.3
  • 9
    • 0034625073 scopus 로고    scopus 로고
    • Investigation into the sources of superoxide in human blood vessels: Angiotensin II increases superoxide production in human internal mammary arteries
    • Berry C, Hamilton CA, Brosnan MJ, et al. Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries. Circulation 2000; 101: 2206-12.
    • (2000) Circulation , vol.101 , pp. 2206-2212
    • Berry, C.1    Hamilton, C.A.2    Brosnan, M.J.3
  • 10
    • 0035097953 scopus 로고    scopus 로고
    • Superoxide excess in hypertension and aging: A common cause of endothelial dysfunction
    • Hamilton CA, Brosnan MJ, McIntyre M, Graham D, Dominiczak AF. Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. Hypertension 2001; 37:529-34.
    • (2001) Hypertension , vol.37 , pp. 529-534
    • Hamilton, C.A.1    Brosnan, M.J.2    McIntyre, M.3    Graham, D.4    Dominiczak, A.F.5
  • 11
    • 0036841861 scopus 로고    scopus 로고
    • NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels
    • Hamilton CA, Brosnan MJ, Al-Benna S, Berg G, Dominiczak AF. NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels. Hypertension 2002;40:755-62.
    • (2002) Hypertension , vol.40 , pp. 755-762
    • Hamilton, C.A.1    Brosnan, M.J.2    Al-Benna, S.3    Berg, G.4    Dominiczak, A.F.5
  • 12
    • 0036464217 scopus 로고    scopus 로고
    • Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats
    • Brosnan MJ, Hamilton CA, Graham D, Lygate CA, Jardine E, Dominiczak AF. Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats. J Hypertens 2002; 20:281-6.
    • (2002) J Hypertens , vol.20 , pp. 281-286
    • Brosnan, M.J.1    Hamilton, C.A.2    Graham, D.3    Lygate, C.A.4    Jardine, E.5    Dominiczak, A.F.6
  • 13
    • 0036224781 scopus 로고    scopus 로고
    • Xanthine oxidase is involved in free radical production in type 1 diabetes: Protection by allopurinol
    • Desco MC, Asensi M, Marquez R, et al. Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol. Diabetes 2002; 51: 1118-24.
    • (2002) Diabetes , vol.51 , pp. 1118-1124
    • Desco, M.C.1    Asensi, M.2    Marquez, R.3
  • 14
    • 0038476475 scopus 로고    scopus 로고
    • Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice
    • Matsumoto S, Koshiishi I, Inoguchi T, Nawata H, Utsumi H. Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice. Free Radic Res 2003; 37: 767-72.
    • (2003) Free Radic Res , vol.37 , pp. 767-772
    • Matsumoto, S.1    Koshiishi, I.2    Inoguchi, T.3    Nawata, H.4    Utsumi, H.5
  • 15
    • 33644817443 scopus 로고    scopus 로고
    • Low-density lipo-protein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease
    • Al-Benna S, Hamilton CA, McClure JD, et al. Low-density lipo-protein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease. Arterioscler Thromb Vasc Biol 2006; 26: 218-23.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 218-223
    • Al-Benna, S.1    Hamilton, C.A.2    McClure, J.D.3
  • 16
    • 0035800889 scopus 로고    scopus 로고
    • Methods of detection of vascular reactive species: Nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite
    • Tarpey MM, Fridovich I. Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ Res 2001; 89: 224-36.
    • (2001) Circ Res , vol.89 , pp. 224-236
    • Tarpey, M.M.1    Fridovich, I.2
  • 18
    • 0035941267 scopus 로고    scopus 로고
    • Lucigenin chemiluminescence assay for superoxide detection
    • Afanas'ev IB. Lucigenin chemiluminescence assay for superoxide detection. Circ Res 2001; 89: E46.
    • (2001) Circ Res , vol.89
    • Afanas'ev, I.B.1
  • 19
    • 0038368985 scopus 로고    scopus 로고
    • Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: Potential implications in intracellular fluorescence detection of superoxide
    • Zhao H, Kalivendi S, Zhang H, et al. Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide. Free Radic Biol Med 2003; 34: 1359-68.
    • (2003) Free Radic Biol Med , vol.34 , pp. 1359-1368
    • Zhao, H.1    Kalivendi, S.2    Zhang, H.3
  • 20
    • 17644394600 scopus 로고    scopus 로고
    • Zhao H, Joseph J, Fales HM, et al. Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence. Proc Natl Acad Sci U S A. 2005; 102: 5727-32. Erratum in: Proc Natl Acad Sci U S A 2005; 102: 9086.
    • Zhao H, Joseph J, Fales HM, et al. Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence. Proc Natl Acad Sci U S A. 2005; 102: 5727-32. Erratum in: Proc Natl Acad Sci U S A 2005; 102: 9086.
  • 21
    • 4544363652 scopus 로고    scopus 로고
    • Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay
    • Fink B, Laude K, McCann L, Doughan A, Harrison DG, Dikalov S. Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay. Am J Physiol Cell Physiol 2004; 287: C895-902.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Fink, B.1    Laude, K.2    McCann, L.3    Doughan, A.4    Harrison, D.G.5    Dikalov, S.6
  • 22
    • 0033966327 scopus 로고    scopus 로고
    • A new approach for extracellular spin trapping of nitroglycerin-induced superoxide radicals both in vitro and in vivo
    • Fink B, Dikalov S, Bassenge E. A new approach for extracellular spin trapping of nitroglycerin-induced superoxide radicals both in vitro and in vivo. Free Radic Biol Med 2000; 28: 121-8.
    • (2000) Free Radic Biol Med , vol.28 , pp. 121-128
    • Fink, B.1    Dikalov, S.2    Bassenge, E.3
  • 23
    • 0037453094 scopus 로고    scopus 로고
    • Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: Relation to endothelium-dependent vasodilation
    • Spiekermann S, Landmesser U, Dikalov S, et al. Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation 2003; 107: 1383-9.
    • (2003) Circulation , vol.107 , pp. 1383-1389
    • Spiekermann, S.1    Landmesser, U.2    Dikalov, S.3
  • 24
    • 27744606565 scopus 로고    scopus 로고
    • ESR techniques for the detection of nitric oxide in vivo and in tissues
    • Dikalov S, Fink B. ESR techniques for the detection of nitric oxide in vivo and in tissues. Methods Enzymol 2005; 396: 597-610.
    • (2005) Methods Enzymol , vol.396 , pp. 597-610
    • Dikalov, S.1    Fink, B.2
  • 25
    • 2542576227 scopus 로고    scopus 로고
    • C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils
    • Wyche KE, Wang SS, Griendling KK, et al. C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils. Hypertension 2004; 43: 1246-51.
    • (2004) Hypertension , vol.43 , pp. 1246-1251
    • Wyche, K.E.1    Wang, S.S.2    Griendling, K.K.3
  • 26
    • 21544442588 scopus 로고    scopus 로고
    • NADPH oxidase-dependent superoxide production is associated with carotid intima-media thickness in subjects free of clinical atherosclerotic disease
    • Zalba G, Beloqui O, San Jose G, Moreno MU, Fortuno A, Diez J. NADPH oxidase-dependent superoxide production is associated with carotid intima-media thickness in subjects free of clinical atherosclerotic disease. Arterioscler Thromb Vasc Biol 2005; 25: 1452-7.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1452-1457
    • Zalba, G.1    Beloqui, O.2    San Jose, G.3    Moreno, M.U.4    Fortuno, A.5    Diez, J.6
  • 27
    • 33644768153 scopus 로고    scopus 로고
    • Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome
    • Fortuno A, San Jose G, Moreno MU, Beloqui O, Diez J, Zalba G. Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome. Diabetes 2006; 55: 209-15.
    • (2006) Diabetes , vol.55 , pp. 209-215
    • Fortuno, A.1    San Jose, G.2    Moreno, M.U.3    Beloqui, O.4    Diez, J.5    Zalba, G.6
  • 28
    • 20144373060 scopus 로고    scopus 로고
    • Reduction of Gsun1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress
    • McBride MW, Brosnan MJ, Mathers J, et al. Reduction of Gsun1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress. Hypertension 2005; 45: 786-92.
    • (2005) Hypertension , vol.45 , pp. 786-792
    • McBride, M.W.1    Brosnan, M.J.2    Mathers, J.3
  • 29
    • 34247171317 scopus 로고    scopus 로고
    • The association between pre-hypertension status and oxidative stress markers related to atherosclerotic disease: The ATTICA study
    • in press. doi:10.1016/j.atherosclerosis.2006.04.030
    • Chrysohoou C, Panagiotakos DB, Pitsavos C, et al. The association between pre-hypertension status and oxidative stress markers related to atherosclerotic disease: The ATTICA study. Atherosclerosis 2006; in press. doi:10.1016/j.atherosclerosis.2006.04.030.
    • (2006) Atherosclerosis
    • Chrysohoou, C.1    Panagiotakos, D.B.2    Pitsavos, C.3
  • 30
    • 33645561623 scopus 로고    scopus 로고
    • Isoprostanes and other markers of peroxidation in atherosclerosis
    • Patrignani P, Tacconelli S. Isoprostanes and other markers of peroxidation in atherosclerosis. Biomarkers 2005; 10 Suppl 1: S24-9.
    • (2005) Biomarkers , vol.10 , Issue.SUPPL. 1
    • Patrignani, P.1    Tacconelli, S.2
  • 31
    • 0033667376 scopus 로고    scopus 로고
    • Plasma protein thiol oxidation and carbonyl formation in chronic renal failure
    • Himmelfarb J, McMonagle E, McMenamin E. Plasma protein thiol oxidation and carbonyl formation in chronic renal failure. Kidney Int 2000; 58: 2571-8.
    • (2000) Kidney Int , vol.58 , pp. 2571-2578
    • Himmelfarb, J.1    McMonagle, E.2    McMenamin, E.3
  • 32
    • 0036833743 scopus 로고    scopus 로고
    • The elephant in uremia: Oxidant stress as a unifying concept of cardiovascular disease in uremia
    • Himmelfarb J, Stenvinkel P, Ikizler TA, Hakim RM. The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int 2002; 62: 1524-38.
    • (2002) Kidney Int , vol.62 , pp. 1524-1538
    • Himmelfarb, J.1    Stenvinkel, P.2    Ikizler, T.A.3    Hakim, R.M.4
  • 33
    • 0142057430 scopus 로고    scopus 로고
    • Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease
    • Blankenberg S, Rupprecht HJ, Bickel C, et al. Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease. N Engl J Med 2003; 349: 1605-13.
    • (2003) N Engl J Med , vol.349 , pp. 1605-1613
    • Blankenberg, S.1    Rupprecht, H.J.2    Bickel, C.3
  • 34
    • 0035960677 scopus 로고    scopus 로고
    • Heitzer T, Schlinzig T, Krohn K, Meinertz T, Münzel T. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 2001; 104: 2673-8. Erratum in: Circulation 2003; 108: 500.
    • Heitzer T, Schlinzig T, Krohn K, Meinertz T, Münzel T. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 2001; 104: 2673-8. Erratum in: Circulation 2003; 108: 500.
  • 37
  • 38
    • 0035312651 scopus 로고    scopus 로고
    • Rapid improvement of nitric oxide bioavailability after lipid-lowering therapy with cerivastatin within two weeks
    • John S, Delles C, Jacobi J, et al. Rapid improvement of nitric oxide bioavailability after lipid-lowering therapy with cerivastatin within two weeks. J Am Coll Cardiol 2001; 37: 1351-8.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1351-1358
    • John, S.1    Delles, C.2    Jacobi, J.3
  • 39
    • 14644416010 scopus 로고    scopus 로고
    • Augmentation index, pulse pressure amplification and superoxide anion production in patients with coronary artery disease
    • Wykretowicz A, Guzik P, Kasinowski R, et al. Augmentation index, pulse pressure amplification and superoxide anion production in patients with coronary artery disease. Int J Cardiol 2005; 99: 289-94.
    • (2005) Int J Cardiol , vol.99 , pp. 289-294
    • Wykretowicz, A.1    Guzik, P.2    Kasinowski, R.3
  • 40
    • 34547910231 scopus 로고    scopus 로고
    • High-fidelity phenotyping of aortic compliance and vascular superoxide production unravels functional relationship between oxidative stress and vascular stiffness in humans
    • abstract
    • Delles C, Zimmerli LU, McGrane DJ, et al. High-fidelity phenotyping of aortic compliance and vascular superoxide production unravels functional relationship between oxidative stress and vascular stiffness in humans. J Hypertans 2006;24 (suppl 4): S157 (abstract).
    • (2006) J Hypertans , vol.24 , Issue.SUPPL. 4
    • Delles, C.1    Zimmerli, L.U.2    McGrane, D.J.3
  • 42
    • 33747291923 scopus 로고    scopus 로고
    • The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study
    • Fan M, Kahonen M, Rontu R, et al. The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study. Am Heart J 2006; 152: 538-42.
    • (2006) Am Heart J , vol.152 , pp. 538-542
    • Fan, M.1    Kahonen, M.2    Rontu, R.3
  • 43
    • 33745128706 scopus 로고    scopus 로고
    • C242T polymorphism in CYBA gene (p22phox) and risk of coronary artery disease in a population of Caucassian Italians
    • Nasti S, Spallarossa P, Altieri P, et al. C242T polymorphism in CYBA gene (p22phox) and risk of coronary artery disease in a population of Caucassian Italians. Dis Markers 2006; 22: 167-73.
    • (2006) Dis Markers , vol.22 , pp. 167-173
    • Nasti, S.1    Spallarossa, P.2    Altieri, P.3
  • 45
    • 0011910306 scopus 로고
    • Development of a strain of spontaneously hypertensive rats
    • Okamoto Y, Aoki K. Development of a strain of spontaneously hypertensive rats. Jpn Circ J 1963; 27: 282-93.
    • (1963) Jpn Circ J , vol.27 , pp. 282-293
    • Okamoto, Y.1    Aoki, K.2
  • 46
    • 0016338812 scopus 로고
    • Importance of genetic factors in stroke: An evidence obtained by selective breeding of a stroke-prone and -resistant SHR
    • Yamori Y, Nagaoka A, Okamoto K. Importance of genetic factors in stroke: An evidence obtained by selective breeding of a stroke-prone and -resistant SHR. Jpn Circ J 1974; 38: 1095-100.
    • (1974) Jpn Circ J , vol.38 , pp. 1095-1100
    • Yamori, Y.1    Nagaoka, A.2    Okamoto, K.3
  • 47
    • 0029155334 scopus 로고
    • Blood pressure in genetically hypertensive rats: Influence of the Y chromosome
    • Davidson AO, Schork N, Jaques BC, et al. Blood pressure in genetically hypertensive rats: Influence of the Y chromosome. Hypertension 1995; 26:452-9.
    • (1995) Hypertension , vol.26 , pp. 452-459
    • Davidson, A.O.1    Schork, N.2    Jaques, B.C.3
  • 48
    • 10344259145 scopus 로고    scopus 로고
    • Quantitative trait loci in genetically hypertensive rats: Possible sex specificity
    • Clark JS, Jeffs B, Davidson AO, et al. Quantitative trait loci in genetically hypertensive rats: possible sex specificity. Hypertension 1996; 28: 898-906.
    • (1996) Hypertension , vol.28 , pp. 898-906
    • Clark, J.S.1    Jeffs, B.2    Davidson, A.O.3
  • 49
    • 0345286868 scopus 로고    scopus 로고
    • Gene transfer of endothelial nitric oxide synthase improves nitric oxide-dependent endothelial function in a hypertensive rat model
    • Alexander MY, Brosnan MJ, Hamilton CA, et al. Gene transfer of endothelial nitric oxide synthase improves nitric oxide-dependent endothelial function in a hypertensive rat model. Cardiovasc Res 1999; 43: 798-807.
    • (1999) Cardiovasc Res , vol.43 , pp. 798-807
    • Alexander, M.Y.1    Brosnan, M.J.2    Hamilton, C.A.3
  • 50
    • 0033021938 scopus 로고    scopus 로고
    • Superoxide anion production is increased in a model of genetic hypertension - Role of the endothelium
    • Kerr S, Brosnan MJ, McIntyre M, Reid JL, Dominiczak AF, Hamilton CA. Superoxide anion production is increased in a model of genetic hypertension - Role of the endothelium. Hypertension 1999; 33: 1353-8.
    • (1999) Hypertension , vol.33 , pp. 1353-1358
    • Kerr, S.1    Brosnan, M.J.2    McIntyre, M.3    Reid, J.L.4    Dominiczak, A.F.5    Hamilton, C.A.6
  • 51
    • 0036184316 scopus 로고    scopus 로고
    • Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension
    • Fennell JP, Brosnan MJ, Frater AJ, et al. Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension. Gene Ther 2002; 9: 110-7.
    • (2002) Gene Ther , vol.9 , pp. 110-117
    • Fennell, J.P.1    Brosnan, M.J.2    Frater, A.J.3
  • 52
    • 0030845876 scopus 로고    scopus 로고
    • Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus
    • Jeffs B, Clark JS, Anderson NH, et al. Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Nat Genet 1997; 16: 364-7.
    • (1997) Nat Genet , vol.16 , pp. 364-367
    • Jeffs, B.1    Clark, J.S.2    Anderson, N.H.3
  • 53
    • 0030659604 scopus 로고    scopus 로고
    • Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains
    • Markel P, Shu P, Ebeling C, et al. Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat Genet 1997; 17: 280-4.
    • (1997) Nat Genet , vol.17 , pp. 280-284
    • Markel, P.1    Shu, P.2    Ebeling, C.3
  • 54
    • 0033966178 scopus 로고    scopus 로고
    • Applicability of a "speed" congenic strategy to dissect blood pressure quantitative trait loci on rat chromosome 2
    • Jeffs B, Negrin CD, Graham D, et al. Applicability of a "speed" congenic strategy to dissect blood pressure quantitative trait loci on rat chromosome 2. Hypertension 2000; 35: 179-87.
    • (2000) Hypertension , vol.35 , pp. 179-187
    • Jeffs, B.1    Negrin, C.D.2    Graham, D.3
  • 55
    • 0034116716 scopus 로고    scopus 로고
    • Congenic rats for hypertension: How useful are they for the hunting of hypertension genes?
    • Nabika T, Kobayashi Y, Yamori Y. Congenic rats for hypertension: how useful are they for the hunting of hypertension genes? Clin Exp Pharmacol Physiol 2000; 27: 251-6.
    • (2000) Clin Exp Pharmacol Physiol , vol.27 , pp. 251-256
    • Nabika, T.1    Kobayashi, Y.2    Yamori, Y.3
  • 57
    • 0037340133 scopus 로고    scopus 로고
    • McBride MW, Carr FJ, Graham D, et al. Microarray analysis of rat chromosome 2 congenic strains. Hypertension 2003; 41: 847-53. Erratum in: Hypertension 2003; 41: e13.
    • McBride MW, Carr FJ, Graham D, et al. Microarray analysis of rat chromosome 2 congenic strains. Hypertension 2003; 41: 847-53. Erratum in: Hypertension 2003; 41: e13.
  • 58
    • 0032958470 scopus 로고    scopus 로고
    • Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
    • Aitman TJ, Glazier AM, Wallace CA, et al. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet 1999; 21: 76-83.
    • (1999) Nat Genet , vol.21 , pp. 76-83
    • Aitman, T.J.1    Glazier, A.M.2    Wallace, C.A.3
  • 59
    • 0007996162 scopus 로고    scopus 로고
    • The role of glutathione S-transferases as a defense against reactive electrophiles in the blood vessel wall
    • He NG, Awasthi S, Singhal SS, Trent MB, Boor PJ. The role of glutathione S-transferases as a defense against reactive electrophiles in the blood vessel wall. Toxicol Appl Pharmacol 1998; 152: 83-9.
    • (1998) Toxicol Appl Pharmacol , vol.152 , pp. 83-89
    • He, N.G.1    Awasthi, S.2    Singhal, S.S.3    Trent, M.B.4    Boor, P.J.5
  • 60
    • 0029561598 scopus 로고
    • The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
    • Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 1995; 30: 445-600.
    • (1995) Crit Rev Biochem Mol Biol , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 61
    • 0032874845 scopus 로고    scopus 로고
    • Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress
    • Hayes JD, McLellan LI. Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Radic Res 1999; 31: 273-300.
    • (1999) Free Radic Res , vol.31 , pp. 273-300
    • Hayes, J.D.1    McLellan, L.I.2
  • 62
    • 0033854560 scopus 로고    scopus 로고
    • Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats
    • Vaziri ND, Wang XQ, Oveisi F, Rad B. Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats. Hypertension 2000; 36: 142-6.
    • (2000) Hypertension , vol.36 , pp. 142-146
    • Vaziri, N.D.1    Wang, X.Q.2    Oveisi, F.3    Rad, B.4
  • 63
    • 0027367823 scopus 로고
    • Identification of classmu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13
    • Pearson WR, Vorachek WR, Xu SJ, et al. Identification of classmu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13. Am J Hum Genet 1993; 53: 220-33.
    • (1993) Am J Hum Genet , vol.53 , pp. 220-233
    • Pearson, W.R.1    Vorachek, W.R.2    Xu, S.J.3
  • 64
    • 0032836443 scopus 로고    scopus 로고
    • Distinctive structure of the human GSTM3 gene-inverted orientation relative to the mu class glutathione transferase gene cluster
    • Patskovsky YV, Huang MQ, Takayama T, Listowsky I, Pearson WR. Distinctive structure of the human GSTM3 gene-inverted orientation relative to the mu class glutathione transferase gene cluster. Arch Biochem Biophys 1999; 361: 85-93.
    • (1999) Arch Biochem Biophys , vol.361 , pp. 85-93
    • Patskovsky, Y.V.1    Huang, M.Q.2    Takayama, T.3    Listowsky, I.4    Pearson, W.R.5
  • 65
    • 0032488893 scopus 로고    scopus 로고
    • Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion
    • Xu S, Wing Y, Roe B, Pearson WR. Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion. J Biol Chem 1998; 273: 3517-27.
    • (1998) J Biol Chem , vol.273 , pp. 3517-3527
    • Xu, S.1    Wing, Y.2    Roe, B.3    Pearson, W.R.4
  • 68
    • 0036021719 scopus 로고    scopus 로고
    • A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer
    • Lilogtou T, Walters M, Maloney P, Youngson J, Field JK. A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer. Lung Cancer 2002; 37: 143-6.
    • (2002) Lung Cancer , vol.37 , pp. 143-146
    • Lilogtou, T.1    Walters, M.2    Maloney, P.3    Youngson, J.4    Field, J.K.5
  • 69
    • 0027306050 scopus 로고
    • Genetic risk and carcinogen exposure: A common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer
    • Bell DA, Taylor JA, Paulson DF, Robertson CN, Mohler JL, Lucier GW. Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer. J Natl Cancer Inst 1993; 85: 1159-64.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1159-1164
    • Bell, D.A.1    Taylor, J.A.2    Paulson, D.F.3    Robertson, C.N.4    Mohler, J.L.5    Lucier, G.W.6
  • 70
    • 0027370757 scopus 로고
    • Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer
    • Zhong S, Wyllie AH, Barnes D, Wolf CR, Spurr NK. Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer. Carcinogenesis 1993; 14: 1821-4.
    • (1993) Carcinogenesis , vol.14 , pp. 1821-1824
    • Zhong, S.1    Wyllie, A.H.2    Barnes, D.3    Wolf, C.R.4    Spurr, N.K.5
  • 71
    • 0037258372 scopus 로고    scopus 로고
    • Polymorphisms for chemical metabolizing genes and risk for cervical neoplasia
    • Sierra-Torres CH, Au WW, Arrastia CD, et al. Polymorphisms for chemical metabolizing genes and risk for cervical neoplasia. Environ Mol Mutagen 2003; 41: 69-76.
    • (2003) Environ Mol Mutagen , vol.41 , pp. 69-76
    • Sierra-Torres, C.H.1    Au, W.W.2    Arrastia, C.D.3
  • 72
    • 0038297510 scopus 로고    scopus 로고
    • Higher glutathione transferase GSTM1 0/0 genotype frequency in young thyroid carcinoma patients
    • Canbay E, Dokmetas S, Canbay EI, Sen M, Bardakci F. Higher glutathione transferase GSTM1 0/0 genotype frequency in young thyroid carcinoma patients. Curr Med Res Opin 2003; 19: 102-6.
    • (2003) Curr Med Res Opin , vol.19 , pp. 102-106
    • Canbay, E.1    Dokmetas, S.2    Canbay, E.I.3    Sen, M.4    Bardakci, F.5
  • 73
    • 0038749172 scopus 로고    scopus 로고
    • Gene polymorphisms in detoxification enzymes as susceptibility factor for head and neck cancer?
    • Gronau S, Koenig-Greger D, Jerg M, Riechelmann H. Gene polymorphisms in detoxification enzymes as susceptibility factor for head and neck cancer? Otolaryngol Head Neck Surg 2003; 128: 674-80.
    • (2003) Otolaryngol Head Neck Surg , vol.128 , pp. 674-680
    • Gronau, S.1    Koenig-Greger, D.2    Jerg, M.3    Riechelmann, H.4
  • 74
    • 33748425479 scopus 로고    scopus 로고
    • Glutathione S-transferase M1 and P1 genotype, passive smoking, and peak expiratory flow in asthma
    • Palmer CN, Doney AS, Lee SP, et al. Glutathione S-transferase M1 and P1 genotype, passive smoking, and peak expiratory flow in asthma. Pediatrics 2006; 118: 710-6.
    • (2006) Pediatrics , vol.118 , pp. 710-716
    • Palmer, C.N.1    Doney, A.S.2    Lee, S.P.3
  • 75
    • 0347948542 scopus 로고    scopus 로고
    • Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: Randomised, placebo-controlled crossover study
    • Gilliland FD, Li YF, Saxon A, Diaz-Sanchez D. Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study. Lancet 2004; 363: 119-25.
    • (2004) Lancet , vol.363 , pp. 119-125
    • Gilliland, F.D.1    Li, Y.F.2    Saxon, A.3    Diaz-Sanchez, D.4
  • 76
    • 0042343898 scopus 로고    scopus 로고
    • Analysis ofthe polymorphic alleles of genes encoding phase 1 and phase 2 detoxication enzymes in patients with endometriosis
    • Ivashchenko TE, Shved NIu, Kramareva NA, Ailamazian EK, Baranov VS. Analysis ofthe polymorphic alleles of genes encoding phase 1 and phase 2 detoxication enzymes in patients with endometriosis. Genetika 2003; 39: 525-9.
    • (2003) Genetika , vol.39 , pp. 525-529
    • Ivashchenko, T.E.1    Shved, N.I.2    Kramareva, N.A.3    Ailamazian, E.K.4    Baranov, V.S.5
  • 78
    • 30044437819 scopus 로고    scopus 로고
    • A common variant in the glutathione S transferase gene is associated with elevated markers of inflammation and lipid peroxidation in subjects with diabetes mellitus
    • Hayek T, Stephens JW, Hubbart CS, et al. A common variant in the glutathione S transferase gene is associated with elevated markers of inflammation and lipid peroxidation in subjects with diabetes mellitus. Atherosclerosis 2006; 184: 404-12.
    • (2006) Atherosclerosis , vol.184 , pp. 404-412
    • Hayek, T.1    Stephens, J.W.2    Hubbart, C.S.3
  • 79
    • 2642524416 scopus 로고    scopus 로고
    • Genetic analysis of 22 candidate genes for hypertension in the Japanese population
    • Iwai N, Tago N, Yasui N, et al. Genetic analysis of 22 candidate genes for hypertension in the Japanese population. J Hypertens 2004; 22: 1119-26.
    • (2004) J Hypertens , vol.22 , pp. 1119-1126
    • Iwai, N.1    Tago, N.2    Yasui, N.3
  • 80
    • 0034081052 scopus 로고    scopus 로고
    • Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction
    • Wilson MH, Grant PJ, Hardie LJ, Wild CP. Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction. FASEB J 2000; 14: 791-6.
    • (2000) FASEB J , vol.14 , pp. 791-796
    • Wilson, M.H.1    Grant, P.J.2    Hardie, L.J.3    Wild, C.P.4
  • 81
    • 0042027548 scopus 로고    scopus 로고
    • Interactive effect of the glutathione S-transferase genes and cigarette smoking on occurrence and severity of coronary artery risk
    • Masetti S, Botto N, Manfredi S, et al. Interactive effect of the glutathione S-transferase genes and cigarette smoking on occurrence and severity of coronary artery risk. J Mol Med 2003; 81: 488-94.
    • (2003) J Mol Med , vol.81 , pp. 488-494
    • Masetti, S.1    Botto, N.2    Manfredi, S.3
  • 82
    • 33646375416 scopus 로고    scopus 로고
    • T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking
    • Abu-Amero KK, Al-Boudari OM, Mohamed GH, Dzimiri N. T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking. BMC Med Genet 2006; 7: 38.
    • (2006) BMC Med Genet , vol.7 , pp. 38
    • Abu-Amero, K.K.1    Al-Boudari, O.M.2    Mohamed, G.H.3    Dzimiri, N.4
  • 83
    • 12244281869 scopus 로고    scopus 로고
    • Association between the risk of coronary artery disease in South Asians and a deletion polymorphism in glutathione S-transferase M1
    • Wilson MH, Grant PJ, Kain K, Warner DP, Wild CP. Association between the risk of coronary artery disease in South Asians and a deletion polymorphism in glutathione S-transferase M1. Biomarkers 2003; 8: 43-50.
    • (2003) Biomarkers , vol.8 , pp. 43-50
    • Wilson, M.H.1    Grant, P.J.2    Kain, K.3    Warner, D.P.4    Wild, C.P.5
  • 84
    • 0036227937 scopus 로고    scopus 로고
    • Glutathione S-transferase mu1 deficiency, cigarette smoking and coronary artery disease
    • Wang XL, Greco M, Sim AS, Duarte N, Wang J, Wilcken DE. Glutathione S-transferase mu1 deficiency, cigarette smoking and coronary artery disease. J Cardiovasc Risk 2002; 9: 25-31.
    • (2002) J Cardiovasc Risk , vol.9 , pp. 25-31
    • Wang, X.L.1    Greco, M.2    Sim, A.S.3    Duarte, N.4    Wang, J.5    Wilcken, D.E.6
  • 85
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: Role in cardiovascular biology and disease
    • Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 2000; 86: 494-501.
    • (2000) Circ Res , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 86
    • 0035678477 scopus 로고    scopus 로고
    • Oxidative stress in arterial hypertension: Role of NAD(P)H oxidase
    • Zalba G, San Jose G, Moreno MU, et al. Oxidative stress in arterial hypertension: role of NAD(P)H oxidase. Hypertension 2001; 38: 1395-9.
    • (2001) Hypertension , vol.38 , pp. 1395-1399
    • Zalba, G.1    San Jose, G.2    Moreno, M.U.3
  • 87
    • 0033105874 scopus 로고    scopus 로고
    • NADPH oxidase: An update
    • Babior BM. NADPH oxidase: an update. Blood 1999; 93: 1464-76.
    • (1999) Blood , vol.93 , pp. 1464-1476
    • Babior, B.M.1
  • 89
    • 0347711117 scopus 로고    scopus 로고
    • NADPH oxidases: Not just for leukocytes anymore!
    • Bokoch GM, Knaus, UG. NADPH oxidases: not just for leukocytes anymore! Trends Biochem Sci 2003; 28: 502-8.
    • (2003) Trends Biochem Sci , vol.28 , pp. 502-508
    • Bokoch, G.M.1    Knaus, U.G.2
  • 90
    • 0042810670 scopus 로고    scopus 로고
    • Vascular NAD(P)H oxidases: Specific features, expression, and regulation
    • Lassegue B, Clempus RE. Vascular NAD(P)H oxidases: specific features, expression, and regulation. Am J Physiol Regul Integr Comp Physiol 2003; 285: R277-97.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.285
    • Lassegue, B.1    Clempus, R.E.2
  • 91
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Dröge W. Free radicals in the physiological control of cell function. Physiol Rev 2002; 82: 47-95.
    • (2002) Physiol Rev , vol.82 , pp. 47-95
    • Dröge, W.1
  • 92
    • 0035725015 scopus 로고    scopus 로고
    • Beswick RA, Dorrance AM, Leite R, Webb RC. NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat. Hypertension 2001; 38: 1107-11.
    • Beswick RA, Dorrance AM, Leite R, Webb RC. NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat. Hypertension 2001; 38: 1107-11.
  • 93
    • 0034085114 scopus 로고    scopus 로고
    • Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats
    • Zalba G, Beaumont FJ, San Jose G, et al. Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats. Hypertension 2000; 35: 1055-61.
    • (2000) Hypertension , vol.35 , pp. 1055-1061
    • Zalba, G.1    Beaumont, F.J.2    San Jose, G.3
  • 94
    • 0036845042 scopus 로고    scopus 로고
    • Dose-dependent regulation of NAD(P)H oxidase expression by angiotensin II in human endothelial cells: Protective effect of angiotensin II type 1 receptor blockade in patients with coronary artery disease
    • Rueckschloss U, Quinn MT, Holtz J, Morawietz H. Dose-dependent regulation of NAD(P)H oxidase expression by angiotensin II in human endothelial cells: protective effect of angiotensin II type 1 receptor blockade in patients with coronary artery disease. Arterioscler Thromb Vasc Biol 2002; 22: 1845-51.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1845-1851
    • Rueckschloss, U.1    Quinn, M.T.2    Holtz, J.3    Morawietz, H.4
  • 95
    • 0037076284 scopus 로고    scopus 로고
    • Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis
    • Itoh S, Umemoto S, Hiromoto M, et al. Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis. Circulation 2002; 105: 2288-95.
    • (2002) Circulation , vol.105 , pp. 2288-2295
    • Itoh, S.1    Umemoto, S.2    Hiromoto, M.3
  • 96
    • 20444415033 scopus 로고    scopus 로고
    • Oxidative stress in atherogenesis and arterial thrombosis: The disconnect between cellular studies and clinical outcomes
    • Madamanchi NR, Hakim ZS, Runge MS. Oxidative stress in atherogenesis and arterial thrombosis: the disconnect between cellular studies and clinical outcomes. J Thromb Haemost 2005; 3: 254-67.
    • (2005) J Thromb Haemost , vol.3 , pp. 254-267
    • Madamanchi, N.R.1    Hakim, Z.S.2    Runge, M.S.3
  • 97
    • 0029783343 scopus 로고    scopus 로고
    • Activation of NADPH oxidase is required for macrophage-mediated oxidation of low-density lipoprotein
    • Aviram M, Rosenblat M, Etzioni A, Levy R. Activation of NADPH oxidase is required for macrophage-mediated oxidation of low-density lipoprotein. Metabolism 1996; 45: 1069-79.
    • (1996) Metabolism , vol.45 , pp. 1069-1079
    • Aviram, M.1    Rosenblat, M.2    Etzioni, A.3    Levy, R.4
  • 98
    • 0034805555 scopus 로고    scopus 로고
    • Expression of p22-phox and gp91-phox, essential components of NADPH oxidase, increases after myocardial infarction
    • Fukui T, Yoshiyama M, Hanatani A, Omura T, Yoshikawa J, Abe Y. Expression of p22-phox and gp91-phox, essential components of NADPH oxidase, increases after myocardial infarction. Biochem Biophys Res Commun 2001; 281: 1200-6.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 1200-1206
    • Fukui, T.1    Yoshiyama, M.2    Hanatani, A.3    Omura, T.4    Yoshikawa, J.5    Abe, Y.6
  • 99
    • 7744232120 scopus 로고    scopus 로고
    • Association of increased phagocytic NADPH oxidas-dependent superoxide production with diminished nitric oxide generation in essential hypertension
    • Fortuno A, Olivan S, Beloqui O, et al. Association of increased phagocytic NADPH oxidas-dependent superoxide production with diminished nitric oxide generation in essential hypertension. J Hypertens 2004; 22: 2169-75.
    • (2004) J Hypertens , vol.22 , pp. 2169-2175
    • Fortuno, A.1    Olivan, S.2    Beloqui, O.3
  • 100
    • 0033209906 scopus 로고    scopus 로고
    • State-of-the-Art lecture. Role of angiotensin and oxidative stress in essential hypertension
    • Romero JC, Reckelholf JF. State-of-the-Art lecture. Role of angiotensin and oxidative stress in essential hypertension. Hypertension 1999; 34: 943-9.
    • (1999) Hypertension , vol.34 , pp. 943-949
    • Romero, J.C.1    Reckelholf, J.F.2
  • 102
    • 1642276271 scopus 로고    scopus 로고
    • Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice
    • Virdis A, Neves MF, Amiri F, Touyz RM, Schiffrin EL. Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice. J Hypertens 2004; 22: 535-42.
    • (2004) J Hypertens , vol.22 , pp. 535-542
    • Virdis, A.1    Neves, M.F.2    Amiri, F.3    Touyz, R.M.4    Schiffrin, E.L.5
  • 103
    • 0037465438 scopus 로고    scopus 로고
    • Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension
    • Li L, Fink GD, Watts SW, et al. Endothelin-1 increases vascular superoxide via endothelin(A)-NADPH oxidase pathway in low-renin hypertension. Circulation 2003; 107: 1053-8.
    • (2003) Circulation , vol.107 , pp. 1053-1058
    • Li, L.1    Fink, G.D.2    Watts, S.W.3
  • 104
    • 0347063994 scopus 로고    scopus 로고
    • NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats
    • Park YM, Park MY, Suh YL, Park JB. NAD(P)H oxidase inhibitor prevents blood pressure elevation and cardiovascular hypertrophy in aldosterone-infused rats. Biochem Biophys Res Commun 2004; 313:812-7.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 812-817
    • Park, Y.M.1    Park, M.Y.2    Suh, Y.L.3    Park, J.B.4
  • 105
    • 0032104153 scopus 로고    scopus 로고
    • Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: Role of a superoxide-producing NADH oxidase
    • De Keulenaer GW, Chappell DC, Ishizaka, N, Nerèm RM, Alexander RW, Griendling KK. Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circ Res 1998; 82: 1094-101.
    • (1998) Circ Res , vol.82 , pp. 1094-1101
    • De Keulenaer, G.W.1    Chappell, D.C.2    Ishizaka, N.3    Nerèm, R.M.4    Alexander, R.W.5    Griendling, K.K.6
  • 106
    • 0344185339 scopus 로고    scopus 로고
    • Role of xanthine oxidoreductase and NAD(P)H oxidase in endothetial superoxide production in response to oscillatory shear stress
    • McNally JS, Davis ME, Giddens DP, et al. Role of xanthine oxidoreductase and NAD(P)H oxidase in endothetial superoxide production in response to oscillatory shear stress. Am J Physiol Heart Circ Physiol 2003; 285: H2290-7.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • McNally, J.S.1    Davis, M.E.2    Giddens, D.P.3
  • 107
    • 0035726286 scopus 로고    scopus 로고
    • Flow pulsatility is a critical determinant of oxidative stress in endothelial cells
    • Silacci P, Desgeorges A, Mazzolai L, Chambaz C, Hayoz D. Flow pulsatility is a critical determinant of oxidative stress in endothelial cells. Hypertension 2001; 38: 1162-6.
    • (2001) Hypertension , vol.38 , pp. 1162-1166
    • Silacci, P.1    Desgeorges, A.2    Mazzolai, L.3    Chambaz, C.4    Hayoz, D.5
  • 108
    • 21544442588 scopus 로고    scopus 로고
    • NADPH oxidase-dependent superoxide production is associated with carotid intima-media thickness in subjects free of clinical atherosclerotic disease
    • Zalba G, Beloqui O, San Jose G, Moreno MU, Fortuno A, Diez J. NADPH oxidase-dependent superoxide production is associated with carotid intima-media thickness in subjects free of clinical atherosclerotic disease. Arterioscler Thromb Vasc Biol 2005; 25: 1452-7.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1452-1457
    • Zalba, G.1    Beloqui, O.2    San Jose, G.3    Moreno, M.U.4    Fortuno, A.5    Diez, J.6
  • 109
    • 33748306000 scopus 로고    scopus 로고
    • Increased phagocytic nicotinamide adenine dinucleotide phosphate oxidase-dependent superoxide production in patients with early chronic kidney disease
    • Fortuno A, Beloqui O, San Jose G, Moreno MU, Zalba G, Diez J. Increased phagocytic nicotinamide adenine dinucleotide phosphate oxidase-dependent superoxide production in patients with early chronic kidney disease. Kidney Int Suppl 2005: S71-5.
    • (2005) Kidney Int Suppl
    • Fortuno, A.1    Beloqui, O.2    San Jose, G.3    Moreno, M.U.4    Zalba, G.5    Diez, J.6
  • 110
    • 0029661428 scopus 로고    scopus 로고
    • p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells
    • Ushio-Fukai M, Zafari AM, Fukui T, Ishizaka N, Griendling KK. p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol Chem 1996; 271: 23317-21.
    • (1996) J Biol Chem , vol.271 , pp. 23317-23321
    • Ushio-Fukai, M.1    Zafari, A.M.2    Fukui, T.3    Ishizaka, N.4    Griendling, K.K.5
  • 111
    • 0035793313 scopus 로고    scopus 로고
    • Polymorphisms and promoter overactivity of the p22(phox) gene in vascular smooth muscle cells from spontaneously hypertensive rats
    • Zalba G, San Jose G, Beaumont FJ, Fortuno MA, Fortuno A, Diez J. Polymorphisms and promoter overactivity of the p22(phox) gene in vascular smooth muscle cells from spontaneously hypertensive rats. Circ Res 2001; 88: 217-22.
    • (2001) Circ Res , vol.88 , pp. 217-222
    • Zalba, G.1    San Jose, G.2    Beaumont, F.J.3    Fortuno, M.A.4    Fortuno, A.5    Diez, J.6
  • 112
    • 22144478334 scopus 로고    scopus 로고
    • NADPH Oxidase-Mediated Oxidative Stress: Genetic Studies of the p22(phox) Gene in Hypertension
    • Zalba G, Jose GS, Moreno MU, Fortuno A, Diez J. NADPH Oxidase-Mediated Oxidative Stress: Genetic Studies of the p22(phox) Gene in Hypertension. Antioxid Redox Signal 2005; 7:1327-36.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1327-1336
    • Zalba, G.1    Jose, G.S.2    Moreno, M.U.3    Fortuno, A.4    Diez, J.5
  • 113
    • 0034607821 scopus 로고    scopus 로고
    • Processing and maturation of flavocytochrome b559 include incorporation of heme as a prerequisite for heterodimer assembly
    • DeLeo FR, Burritt JB, Yu L, Jesaitis AJ, Dinauer MC, Nauseef WM. Processing and maturation of flavocytochrome b559 include incorporation of heme as a prerequisite for heterodimer assembly. J Biol Chem 2000 275: 13986-93.
    • (2000) J Biol Chem , vol.275 , pp. 13986-13993
    • DeLeo, F.R.1    Burritt, J.B.2    Yu, L.3    Jesaitis, A.J.4    Dinauer, M.C.5    Nauseef, W.M.6
  • 114
    • 0031940241 scopus 로고    scopus 로고
    • Polymorphism of the NADH/NADPH oxidase p22 phox gene in patients with coronary artery disease
    • Inoue N, Kawashima, S, Kanazawa K, Yamada S, Akita H, Yokoyama M. Polymorphism of the NADH/NADPH oxidase p22 phox gene in patients with coronary artery disease. Circulation 1998; 97: 135-7.
    • (1998) Circulation , vol.97 , pp. 135-137
    • Inoue, N.1    Kawashima, S.2    Kanazawa, K.3    Yamada, S.4    Akita, H.5    Yokoyama, M.6
  • 115
    • 0034633838 scopus 로고    scopus 로고
    • Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22phox gene on vascular superoxide production in atherosclerosis
    • Guzik TJ, West NE, Black E, et al. Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22phox gene on vascular superoxide production in atherosclerosis. Circulation 2000; 102: 1744-7.
    • (2000) Circulation , vol.102 , pp. 1744-1747
    • Guzik, T.J.1    West, N.E.2    Black, E.3
  • 116
    • 33745467302 scopus 로고    scopus 로고
    • The C242T CYBA polymorphism of the NADPH oxidase is associated with Essential Hypertension
    • Moreno MU, San Jose G, Fortuño A, Beloqui O, Diez J, Zalba G. The C242T CYBA polymorphism of the NADPH oxidase is associated with Essential Hypertension. J Hypertens 2006; 24: 1299-306.
    • (2006) J Hypertens , vol.24 , pp. 1299-1306
    • Moreno, M.U.1    San Jose, G.2    Fortuño, A.3    Beloqui, O.4    Diez, J.5    Zalba, G.6
  • 117
    • 0037664695 scopus 로고    scopus 로고
    • The C242T p22phox polymorphism and endothelium-dependent vasodilation in subjects with hypercholesterolaemia
    • Schneider MP, Hilgers KF, Huang Y, et al. The C242T p22phox polymorphism and endothelium-dependent vasodilation in subjects with hypercholesterolaemia. Clin Sci (Lond) 2003; 105: 97-103.
    • (2003) Clin Sci (Lond) , vol.105 , pp. 97-103
    • Schneider, M.P.1    Hilgers, K.F.2    Huang, Y.3
  • 118
    • 3543011345 scopus 로고    scopus 로고
    • Functional effect of the p22phox -930A/G polymorphism on p22pbox expression and NADPH oxidase activity in hypertension
    • San Jose G, Moreno MU, Olivan S, et al. Functional effect of the p22phox -930A/G polymorphism on p22pbox expression and NADPH oxidase activity in hypertension. Hypertension 2004; 44: 163-9.
    • (2004) Hypertension , vol.44 , pp. 163-169
    • San Jose, G.1    Moreno, M.U.2    Olivan, S.3
  • 119
    • 0036082104 scopus 로고    scopus 로고
    • The C242T-polymorphism of the NADPH/NADH oxidase gene p22phox subunit is not associated with pre-eclampsia
    • Raijmakers MT, Roes EM, Steegers EA, Peters WH. The C242T-polymorphism of the NADPH/NADH oxidase gene p22phox subunit is not associated with pre-eclampsia. J Hum Hypertens 2002; 16:423-5.
    • (2002) J Hum Hypertens , vol.16 , pp. 423-425
    • Raijmakers, M.T.1    Roes, E.M.2    Steegers, E.A.3    Peters, W.H.4
  • 120
    • 0032588543 scopus 로고    scopus 로고
    • The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals
    • Gardemann A, Mages P, Katz N, Tillmanns H, Haberbosch W. The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals. Atherosclerosis 1999; 145: 315-23.
    • (1999) Atherosclerosis , vol.145 , pp. 315-323
    • Gardemann, A.1    Mages, P.2    Katz, N.3    Tillmanns, H.4    Haberbosch, W.5
  • 122
    • 18844370620 scopus 로고    scopus 로고
    • Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension
    • Friese RS, Mahboubi P, Mahapatra NR, et al. Common genetic mechanisms of blood pressure elevation in two independent rodent models of human essential hypertension. Am J Hyperiens 2005; 18: 633-52.
    • (2005) Am J Hyperiens , vol.18 , pp. 633-652
    • Friese, R.S.1    Mahboubi, P.2    Mahapatra, N.R.3
  • 123
    • 0038689472 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase polymorphisms and hypertension
    • Hingorani AD. Endothelial nitric oxide synthase polymorphisms and hypertension. Curr Hypertens Rep 2003; 5: 19-25.
    • (2003) Curr Hypertens Rep , vol.5 , pp. 19-25
    • Hingorani, A.D.1
  • 124
    • 0035723769 scopus 로고    scopus 로고
    • Lack of association between polymorphisms of catelase, copper-zinc superoxide dismutase (SOD), extracellular SOD and andothelial nitric oxide synthase genes and macroangiopathy in patients with type 2 diabetes mellitus
    • Ukkola O, Erkkila PH, Savolainen MJ, Kesaniemi YA. Lack of association between polymorphisms of catelase, copper-zinc superoxide dismutase (SOD), extracellular SOD and andothelial nitric oxide synthase genes and macroangiopathy in patients with type 2 diabetes mellitus. J Intern Med 2001; 249: 451-9.
    • (2001) J Intern Med , vol.249 , pp. 451-459
    • Ukkola, O.1    Erkkila, P.H.2    Savolainen, M.J.3    Kesaniemi, Y.A.4
  • 125
    • 4344649455 scopus 로고    scopus 로고
    • Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in japanese type 2 diabetic patients
    • Hamanishi T, Furuta H, Kato H, et al. Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in japanese type 2 diabetic patients. Diabetes 2004; 53: 2455-60.
    • (2004) Diabetes , vol.53 , pp. 2455-2460
    • Hamanishi, T.1    Furuta, H.2    Kato, H.3
  • 126
    • 0038746696 scopus 로고    scopus 로고
    • Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease
    • Winter JP, Gong Y, Grant PJ, Wild CP. Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease. Coron Artery Dis 2003; 14: 149-53.
    • (2003) Coron Artery Dis , vol.14 , pp. 149-153
    • Winter, J.P.1    Gong, Y.2    Grant, P.J.3    Wild, C.P.4
  • 129
    • 33646188852 scopus 로고    scopus 로고
    • Family-based designs in the age of large-scale gene-association studies
    • Laird NM, Lange C. Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet 2006; 7: 385-94.
    • (2006) Nat Rev Genet , vol.7 , pp. 385-394
    • Laird, N.M.1    Lange, C.2
  • 131
    • 0142059667 scopus 로고    scopus 로고
    • Are we there yet?: Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits
    • Page GP, George V, Go RC, Page PZ, Allison DB. "Are we there yet?": deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits. Am J Hum Genet 2003; 73: 711-9.
    • (2003) Am J Hum Genet , vol.73 , pp. 711-719
    • Page, G.P.1    George, V.2    Go, R.C.3    Page, P.Z.4    Allison, D.B.5
  • 132
    • 1642399172 scopus 로고    scopus 로고
    • Betting odds and genetic associations
    • Thomas DC, Clayton DG. Betting odds and genetic associations. J Natl Cancer Inst 2004; 96: 421-3.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 421-423
    • Thomas, D.C.1    Clayton, D.G.2
  • 133
    • 0141450364 scopus 로고    scopus 로고
    • False discoveries and models for gene discovery
    • van den Oord EJ, Sullivan PF. False discoveries and models for gene discovery. Trends Genet 2003; 19: 537-42.
    • (2003) Trends Genet , vol.19 , pp. 537-542
    • van den Oord, E.J.1    Sullivan, P.F.2
  • 134
    • 1642295096 scopus 로고    scopus 로고
    • Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
    • Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N. Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 2004; 96: 434-42.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 434-442
    • Wacholder, S.1    Chanock, S.2    Garcia-Closas, M.3    El Ghormli, L.4    Rothman, N.5
  • 135
    • 4143134235 scopus 로고    scopus 로고
    • The future of association studies: Gene-based analysis and replication
    • Neale BM, Sham PC. The future of association studies: gene-based analysis and replication. Am J Hum Genet 2004; 75: 353-62.
    • (2004) Am J Hum Genet , vol.75 , pp. 353-362
    • Neale, B.M.1    Sham, P.C.2
  • 138
    • 10744230485 scopus 로고    scopus 로고
    • Global mapping of the yeast genetic interaction network
    • Tong AH, Lesage G, Bader GD, et al. Global mapping of the yeast genetic interaction network. Science 2004; 303: 808-13.
    • (2004) Science , vol.303 , pp. 808-813
    • Tong, A.H.1    Lesage, G.2    Bader, G.D.3
  • 139
    • 11244293921 scopus 로고    scopus 로고
    • A global view of epistasis
    • Moore JH. A global view of epistasis. Nat Genet 2005; 37: 13-4.
    • (2005) Nat Genet , vol.37 , pp. 13-14
    • Moore, J.H.1
  • 140
    • 20844455582 scopus 로고    scopus 로고
    • Genotypiqg over 100,000 SNPs on a pair of oligonucleotide arrays
    • Matsuzaki H, Dong S, Loi H, et al. Genotypiqg over 100,000 SNPs on a pair of oligonucleotide arrays. Nat Methods 2004; 1: 109-11.
    • (2004) Nat Methods , vol.1 , pp. 109-111
    • Matsuzaki, H.1    Dong, S.2    Loi, H.3
  • 141
    • 18144425478 scopus 로고    scopus 로고
    • A genome-wide scalable SNP genotyping assay using microarray technology
    • Gunderson KL, Steemers FJ, Lee G, et al. A genome-wide scalable SNP genotyping assay using microarray technology. Nat Genet 2005; 37: 549-54.
    • (2005) Nat Genet , vol.37 , pp. 549-554
    • Gunderson, K.L.1    Steemers, F.J.2    Lee, G.3
  • 142
    • 0034688194 scopus 로고    scopus 로고
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 145-53. Errata in: N Engl J Med 2000; 342: 1376; N Engl J Med 2000;342:748.
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 145-53. Errata in: N Engl J Med 2000; 342: 1376; N Engl J Med 2000;342:748.
  • 143
    • 0037031094 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002; 360:23-33.
    • (2002) Lancet , vol.360 , pp. 23-33
  • 144
    • 0034619027 scopus 로고    scopus 로고
    • Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomised placebo-controlled trial
    • Boaz M, Smetana S, Weinstein T, et al. Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial. Lancet 2000; 356: 1213-8.
    • (2000) Lancet , vol.356 , pp. 1213-1218
    • Boaz, M.1    Smetana, S.2    Weinstein, T.3
  • 145
    • 0037465430 scopus 로고    scopus 로고
    • Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression: The Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study
    • Salonen RM, Nyyssonen K, Kaikkonen J, et al. Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression: the Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study. Circulation 2003; 107: 947-53.
    • (2003) Circulation , vol.107 , pp. 947-953
    • Salonen, R.M.1    Nyyssonen, K.2    Kaikkonen, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.