C242T Polymorphism in CYBA gene (p22phox) and risk of coronary artery disease in a population of Caucasian Italians

Disease Markers

Volumn 22, Issue 3, 2006, Pages 167-173

  Nasti, Sabina ^a   Spallarossa, Paolo ^a   Altieri, Paola ^a   Garibaldi, Silvano ^a   Fabbi, Patrizia ^a   Polito, Luisa ^a   Bacino, Luca ^a   Brunelli, Michele ^a   Brunelli, Claudio ^a   Barsotti, Antonio ^a   Ghigliotti, Giorgio ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Cardiovascular; Gene; NAD(P)H oxidase; Oxidative stress; Variant

Indexed keywords

NUCLEOTIDE;

AGED; ALLELE; ANGIOCARDIOGRAPHY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; CORONARY BLOOD VESSEL; CYBA GENE; DNA POLYMORPHISM; ETHNIC GROUP; FEMALE; GENE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; RISK; THORAX PAIN;

EID: 33745128706     PISSN: 02780240     EISSN: None     Source Type: Journal    
DOI: 10.1155/2006/458587     Document Type: Article

References (23)

1. H. Azumi, N. Inoue, S. Takeshita, Y. Rikitake, S. Kawashima, Y. Hayashi et al., Expression of NADH/NADPH oxidase p22phox in human coronary arteries. Circulation 100 (1999), 1494-1498.
2. 2- in vascular smooth muscle cells, Cire Res 77 (1995), 29-36.
3. B.M. Babior, Phagocytes and oxidative stress, Am J Med 109 (2000), 33-44.
4. M.R. Bennett, G.I. Evan and S.M. Schwartz, Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques, J Clin Invest 95 (1995), 2266-2274.
5. C. Berry, C.A. Hamilton, M.J. Brosnan, F.G. Magill, G.A. Berg, J.J. McMurray et al., Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries, Circulation 101 (2000), 2206-2212.
6. C. Cahilly, C.M. Ballantyne, D.S. Lim, A. Gotto and A.J. Marian, A variant of p22(phox), involved in generation of reactive oxygen species in the vessel wall, is associated with progression of coronary atherosclerosis, Circ Res 86 (2000), 391-395.
7. H. Cai, N. Duarte, D.E. Wilcken and X.L. Wang, NADH/NADPH oxidase p22 phox C242T polymorphism and coronary artery disease in the Australian population, Eur J Clin Invest 29 (1999), 744-748.
8. M.K. Cathcart, Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages: contributions to atherosclerosis, Arterioscler Thromb Vasc Biol 24 (2004), 23-28.
9. 2- production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA, Proc Natl Acad Sci USA 89 (1992), 10174-10177.
10. A. Gardemann, P. Mages, N. Katz, H. Tillmanns and W. Haberbosch, The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals, Atherosclerosis 145 (1999), 315-323.
11. K.K. Griendling and D.G. Harrison, Dual role of reactive oxygen species in vascular growth, Circ Res 85 (1999), 562-563.
12. K.K. Griendling and G.A. FitzGerald, Oxidative stress and cardiovascular injury: Part I: Basic Mechanisms and In Vivo Monitoring of ROS, Circulation 108 (2003), 1912-1916.
13. T.J. Guzik, N.E. West, E. Black, D. McDonald, C. Ratnatunga, R. Pillai et al., Functional effect of the C242T polymorphism in the NAD(P)H oxidase p22 phox gene on vascular superoxide production in atherosclerosis, Circulation 102 (2000), 1744-1747.
14. N. Inoue, S. Kawashima, K. Kanazawa, S. Yamada, H. Akita and M. Yokoyama, Polymorphism of the NADH/NADPH oxidase p22 phox gene in patients with coronary artery disease, Circulation 97 (1998), 135-137.
15. phox gene polymorphism to angiographic coronary artery disease and endothelial function, Am J Med Genet 86 (1999), 57-61.
16. M. Maytin, J. Leopold and J. Loscalzo, Oxidant stress in the vasculature, Curr Atheroscler Rep 1 (1999), 156-164.
17. Z.S. Nedeljkovic, N. Gokce and J. Loscalzo, Mechanisms of oxidative stress and vascular dysfunction, Postgrad Med J 79 (2003), 195-200.
18. C.A. Parkos, M.C. Dinauer, L.E. Walker, R.A. Allen, A.J. Jesaitis and S.H. Orkin, Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b, Proc Natl Acad Sci USA 85 (1988), 3319-3323.
19. phox gene polymorphism is associated with improved coronary endothelial vasodilator function, Eur Heart J 22 (2001), 96-101.
20. M.S. Spence, P.G. McGlinchey, C.C. Patterson, A.R. Allen, G. Murphy, U. Bayraktutan et al., Investigation of the C242T polymorphism of NAD(P)H oxidase p22 phox gene and ischaemic heart disease using family-based association methods, Clin Sci 105 (2003), 677-682.
21. J.C. Tsai, M. Jain, C.M. Hsieh, W.S. Lee, M. Yoshizumi, C. Patterson et al., Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells, J Biol Chem 271 (1996), 3667-3670.
22. M. Ushio-Fukai, A.M. Zafari, T. Fukui, N. Ishizaka, K.K. Griendling, .p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells, J Biol Chem 271 (1996), 23317-23321.
23. F.A. van de Loo, M.B. Bennink, O.J. Arntz, R.L. Smeets, E. Lubberts, L.A. Joosten et al., Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models, Am J Pathol 163 (2003), 1525-1537.