-
1
-
-
10744230485
-
Global mapping of the yeast genetic interaction network
-
Tong, A.H.Y. et al. Global mapping of the yeast genetic interaction network. Science 303, 808-813 (2004).
-
(2004)
Science
, vol.303
, pp. 808-813
-
-
Tong, A.H.Y.1
-
2
-
-
0035830860
-
Cell biology - Principles for the buffering of genetic variation
-
Hartman, J.L., Garvik, B. & Hartwell, L. Cell biology - Principles for the buffering of genetic variation. Science 291, 1001-1004 (2001)
-
(2001)
Science
, vol.291
, pp. 1001-1004
-
-
Hartman, J.L.1
Garvik, B.2
Hartwell, L.3
-
3
-
-
0033518234
-
From molecular to modular cell biology
-
Hartwell, L.H., Hopfield, J.J., Leibler, S. & Murray, A.W. From molecular to modular cell biology. Nature 402, C47-C52 (1999).
-
(1999)
Nature
, vol.402
-
-
Hartwell, L.H.1
Hopfield, J.J.2
Leibler, S.3
Murray, A.W.4
-
4
-
-
0344824417
-
Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network
-
Famili, I., Forster, J., Nielsen, J. & Palsson, B.O. Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network. Proc. Natl. Acad. Sci. USA 100, 13134-13139 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13134-13139
-
-
Famili, I.1
Forster, J.2
Nielsen, J.3
Palsson, B.O.4
-
5
-
-
0002854090
-
-
(eds. Wolf, J.B., Brodie III, E.D. & Wade, M.J.) (Oxford University Press, New York)
-
Phillips, P.C., Otto, S.P. & Whitlock, M.C. Beyond the Average: The Evolutionary Importance of Gene Interactions and Variablity of Epistatic Effects, in Epistasis and the Evolutionary Process (eds. Wolf, J.B., Brodie III, E.D. & Wade, M.J.) 20-38 (Oxford University Press, New York, 2000).
-
(2000)
Beyond the Average: The Evolutionary Importance of Gene Interactions and Variablity of Epistatic Effects in Epistasis and the Evolutionary Process
, pp. 20-38
-
-
Phillips, P.C.1
Otto, S.P.2
Whitlock, M.C.3
-
6
-
-
0141730402
-
The genetic architecture of odor-guided behavior in Drosophila: Epistasis and the transcriptome
-
Anholt, R.R. et al. The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome. Nat. Genet. 35, 180-184 (2003).
-
(2003)
Nat. Genet.
, vol.35
, pp. 180-184
-
-
Anholt, R.R.1
-
7
-
-
0037199968
-
Hierarchical organization of modularity in metabolic networks
-
Ravasz, E., Somera, A.L., Mongru, D.A., Oltvai, Z.N. & Barabasi, A.L. Hierarchical organization of modularity in metabolic networks. Science 297, 1551-1555 (2002).
-
(2002)
Science
, vol.297
, pp. 1551-1555
-
-
Ravasz, E.1
Somera, A.L.2
Mongru, D.A.3
Oltvai, Z.N.4
Barabasi, A.L.5
-
8
-
-
1542288938
-
Global organization of metabolic fluxes in the bacterium Escherichia coli
-
Almaas, E., Kovacs, B., Vicsek, T., Oltvai, Z.N. & Barabasi, A.L. Global organization of metabolic fluxes in the bacterium Escherichia coli. Nature 427, 839-843 (2004).
-
(2004)
Nature
, vol.427
, pp. 839-843
-
-
Almaas, E.1
Kovacs, B.2
Vicsek, T.3
Oltvai, Z.N.4
Barabasi, A.L.5
-
9
-
-
8544223537
-
Hierarchical thinking in network biology: The unbiased modularization of biochemical networks
-
Papin, J.A., Reed, J.L. & Palsson, B.O. Hierarchical thinking in network biology: the unbiased modularization of biochemical networks. Trends Biochem. Sci. 29, 641-647 (2004).
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 641-647
-
-
Papin, J.A.1
Reed, J.L.2
Palsson, B.O.3
-
10
-
-
1042269472
-
Minimal cut sets in biochemical reaction networks
-
Klamt, S. & Gilles, E.D. Minimal cut sets in biochemical reaction networks. Bioinformatics 20, 226-234 (2004).
-
(2004)
Bioinformatics
, vol.20
, pp. 226-234
-
-
Klamt, S.1
Gilles, E.D.2
-
11
-
-
0346095291
-
Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae
-
Ihmels, J., Levy, R. & Barkai, N. Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae. Nat. Biotechnol. 22, 86-92 (2004).
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 86-92
-
-
Ihmels, J.1
Levy, R.2
Barkai, N.3
-
12
-
-
0037941585
-
Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data
-
Segal, E. et al. Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Nat. Genet. 34, 166-176 (2003).
-
(2003)
Nat. Genet.
, vol.34
, pp. 166-176
-
-
Segal, E.1
-
13
-
-
0023737547
-
Deleterious mutations and the evolution of sexual reproduction
-
Kondrashov, A.S. Deleterious Mutations and the Evolution of Sexual Reproduction. Nature 336, 435-440 (1988).
-
(1988)
Nature
, vol.336
, pp. 435-440
-
-
Kondrashov, A.S.1
-
14
-
-
0031458777
-
Test of synergistic interactions among deleterious mutations in bacteria
-
Elena, S.F. & Lenski, R.E. Test of synergistic interactions among deleterious mutations in bacteria. Nature 390, 395-398 (1997).
-
(1997)
Nature
, vol.390
, pp. 395-398
-
-
Elena, S.F.1
Lenski, R.E.2
-
15
-
-
0242542705
-
Patterns of epistasis in RNA viruses: A review of the evidence from vaccine design
-
Burch, C.L., Turner, P.E. & Hanley, K.A. Patterns of epistasis in RNA viruses: a review of the evidence from vaccine design. J. Evol. Biol. 16, 1223-1235 (2003).
-
(2003)
J. Evol. Biol.
, vol.16
, pp. 1223-1235
-
-
Burch, C.L.1
Turner, P.E.2
Hanley, K.A.3
-
16
-
-
0033278903
-
Little evidence for synergism among deleterious mutations in a nonsegmented RNA virus
-
Elena, S.F. Little evidence for synergism among deleterious mutations in a nonsegmented RNA virus. J. Mol. Evol. 49, 703-707 (1999).
-
(1999)
J. Mol. Evol.
, vol.49
, pp. 703-707
-
-
Elena, S.F.1
-
17
-
-
0035055001
-
Epistatic interactions of spontaneous mutations in haploid strains of the yeast Saccharomyces cerevisiae
-
Wloch, D.M., Borts, R.H. & Korona, R. Epistatic interactions of spontaneous mutations in haploid strains of the yeast Saccharomyces cerevisiae. J. Evol. Biol. 14, 310-316 (2001).
-
(2001)
J. Evol. Biol.
, vol.14
, pp. 310-316
-
-
Wloch, D.M.1
Borts, R.H.2
Korona, R.3
-
18
-
-
0033549752
-
Genome complexity, robustness and genetic interactions in digital organisms
-
Lenski, R.E., Ofria, C., Collier, T.C. & Adami, C. Genome complexity, robustness and genetic interactions in digital organisms. Nature 400, 661-664 (1999).
-
(1999)
Nature
, vol.400
, pp. 661-664
-
-
Lenski, R.E.1
Ofria, C.2
Collier, T.C.3
Adami, C.4
-
19
-
-
0036239186
-
Dependence of epistasis on environment and mutation severity as revealed by in silico mutagenesis of phage T7
-
You, L.C. & Yin, J. Dependence of epistasis on environment and mutation severity as revealed by in silico mutagenesis of phage T7. Genetics 160, 1273-1281 (2002).
-
(2002)
Genetics
, vol.160
, pp. 1273-1281
-
-
You, L.C.1
Yin, J.2
-
20
-
-
0041853578
-
Environmental stresses can alleviate the average deleterious effect of mutations
-
Kishony, R. & Leibler, S. Environmental stresses can alleviate the average deleterious effect of mutations. J. Biol. 2, 14 (2003).
-
(2003)
J. Biol.
, vol.2
, pp. 14
-
-
Kishony, R.1
Leibler, S.2
-
21
-
-
1842483226
-
Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli
-
Remold, S.K. & Lenski, R.E. Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli. Nat. Genet. 36, 423-426 (2004).
-
(2004)
Nat. Genet.
, vol.36
, pp. 423-426
-
-
Remold, S.K.1
Lenski, R.E.2
-
22
-
-
0142122303
-
Advances in flux balance analysis
-
Kauffman, K.J., Prakash, P. & Edwards, J.S. Advances in flux balance analysis. Curr. Opin. Biotechnol. 14, 491-496 (2003).
-
(2003)
Curr. Opin. Biotechnol.
, vol.14
, pp. 491-496
-
-
Kauffman, K.J.1
Prakash, P.2
Edwards, J.S.3
-
23
-
-
0037313750
-
Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network
-
Forster, J., Famili, I., Fu, P., Palsson, B.O. & Nielsen, J. Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network. Genome Res. 13, 244-253 (2003).
-
(2003)
Genome Res.
, vol.13
, pp. 244-253
-
-
Forster, J.1
Famili, I.2
Fu, P.3
Palsson, B.O.4
Nielsen, J.5
-
24
-
-
2942624207
-
Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast
-
Papp, B., Pal, C. & Hurst, L.D. Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 429, 661-664 (2004).
-
(2004)
Nature
, vol.429
, pp. 661-664
-
-
Papp, B.1
Pal, C.2
Hurst, L.D.3
-
25
-
-
6944224154
-
Metabolic gene-deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes
-
Fong, S.S. & Palsson, B.O. Metabolic gene-deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes. Nat. Genet. 36, 1056-1058 (2004).
-
(2004)
Nat. Genet.
, vol.36
, pp. 1056-1058
-
-
Fong, S.S.1
Palsson, B.O.2
-
26
-
-
0023081983
-
Metabolic flux and fitness
-
Dykhuizen, D.E., Dean, A.M. & Hartl, D.L. Metabolic flux and fitness. Genetics 115, 25-31 (1987).
-
(1987)
Genetics
, vol.115
, pp. 25-31
-
-
Dykhuizen, D.E.1
Dean, A.M.2
Hartl, D.L.3
-
27
-
-
0037069467
-
Analysis of optimality in natural and perturbed metabolic networks
-
Segrè, D., Vitkup, D. & Church, G.M. Analysis of optimality in natural and perturbed metabolic networks. Proc. Natl. Acad. Sci. USA 99, 15112-15117 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 15112-15117
-
-
Segrè, D.1
Vitkup, D.2
Church, G.M.3
-
28
-
-
0037174670
-
Network motifs: Simple building blocks of complex networks
-
Milo, R. et al. Network motifs: simple building blocks of complex networks. Science 298, 824-827 (2002).
-
(2002)
Science
, vol.298
, pp. 824-827
-
-
Milo, R.1
-
29
-
-
11244290945
-
Multi-knockout genetic network analysis: The Rad6 example
-
IEEE, Stanford, California
-
Kaufman, A., Kupiec, M. & Ruppin, E. Multi-knockout genetic network analysis: the Rad6 example, in 2004 IEEE Computational Systems Bioinformatics Conference 332-340 (IEEE, Stanford, California, 2004).
-
(2004)
2004 IEEE Computational Systems Bioinformatics Conference
, pp. 332-340
-
-
Kaufman, A.1
Kupiec, M.2
Ruppin, E.3
|