Quantitative trait loci in genetically hypertensive rats: Possible sex specificity

Hypertension

Volumn 28, Issue 5, 1996, Pages 898-906

  Clark, James S ^a   Jeffs, Baxter ^a   Davidson, Anne O ^a   Lee, Wai Kwong ^a   Anderson, Niall H ^a   Bihoreau, Marie Therese ^b   Brosnan, M Julia ^a   Devlin, Alison M ^a   Kelman, Andrew W ^a   Lindpaintner, Klaus ^c   Dominiczak, Anna F ^a  

^a WESTERN INFIRMARY   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

genes; inbred strains; spontaneously hypertensive rat

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD PRESSURE MEASUREMENT; CHROMOSOME 2; CHROMOSOME 3; CONFERENCE PAPER; CONTROLLED STUDY; CROSSING OVER; FEMALE; GENE LOCUS; GENETIC LINKAGE; GENETIC MARKER; GENETIC SCREENING; GENOTYPE; HEREDITARY HYPERTENSION; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; RAT; SEX DIFFERENCE; SPONTANEOUSLY HYPERTENSIVE RAT;

EID: 10344259145     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.28.5.898     Document Type: Conference Paper

References (30)

1. Okamoto K, Aoki K. Development of a strain of spontaneously hypertensive rats. Jpn Cirr J. 1963;27:282-293
2. Yamori Y. Physiopathology of the various strains of spontaneously hypertensive rats. In: Genest J, Kurchel O, Hamet P, Cantin M, ed. Hypertension. 2nd ed. New York, NY: McGraw-Hill; 1982:556-581.
3. Hilbert P, Lindpaintner K, Beckmann JS, Senkawa T, Soubrier F, Dubay C, Cartwright P, De Gouyon B, Julier C, Takahasi S, Vincent M, Ganten D, Georges M, Lathrop GM. Chromosomal mapping of two genetic loci associated with blood pressure regulation in hereditary hypertensive rats. Nature. 1991;67:213-224.
4. Jacob HL, Lindpaintner K, Lincoln SE, Kusumi K, Bunker RK, Mao Y-P, Ganten D, Dzau DJ, Lander ES. Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat. Cell. 1991;67:213-224.
5. Kreutz R, Hubner N, Jame's MR, Bihoreau MT, Gauguier D, Lathrop GM, Ganten D, Lindpaintner K. Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10. Proc Natl Acad Sci U S A. 1995;92:8778-8782.
6. Lander ES, Schork NJ. Genetic dissection of complex traits. Science. 1994;264:2037-2048.
7. Serikawa T, Kuramoto T, Hilbert P, Mori M, Yamada J, Dubay CJ, Lindpaintner K, Ganten D, Guene, JL, Lathrop GM, Beckmann JS. Rat gene mapping using PCR-analysed microsatellites. Genetics. 1992;131:701-721.
8. Jacob HJ, Brown DM, Bunker RK, Daly MJ, Dzau VJ, Goodma, G, Koike G, Kren V, Kurtz T, Lernmark T, Pravenec J, Simon JS, Szpirer C, Szpirer J, Trolliet MR, Winer ES, Lander ES. A genetic linkage map of the laboratory rat, Rattus norvegicus. Nat Genet. 1995;9: 63-69.
9. Pravenec M, Gauguier D, Schott JJ, Buard J, Kren V, Bida V, Szprier C, Szprier J, Wang JH, Huang H, St Lezin E, Spence MA, Flodman P, Printz M, Lathrop GM, Vergnaud G, Kurtz TW. Genetic linkage map of the rat derived from recombinant inbred strains. Mamm Genome. 1996;7:117-127.
10. Dominiczak AF, McLaren Y, Kuse, J, Bell DL, Goodfriend TL, Bohr DF, Reid JL. Lateral diffusion and fatty acid composition in vascular smooth muscle membrane from stroke-prone spontaneously hypertensive rats. Am J Hypertens. 1993;6:1003-1008.
11. Davidson AO, Schork N, Jaques BC, Kelman AW, Sutchliffe RG, Reid JL, Dominiczak AF. Blood pressure in generally hypertensive rats: influence of the Y chromosome. Hypertension. 1993;26: 452-459.
12. Dominiczak AF, Devlin AM, Lee WK, Anderson NH, Bohr DL, Reid JL. Vascular smooth muscle polyploidy and cardiac hypertrophy in genetic hypertension. Hypertension. 1996;21:152-759.
13. Devlin AM, Gordon JF, Davidson AO, Clark JS, Hamilton CA, Morton JJ, Campbell AM, Reid JL, Dominiczak AF. The effect of perindopril on vascular smooth muscle polyploidy in stroke-prone spontaneously hypertensive rats. J Hypertens. 1995;13:211-218.
14. Lander ES, Green P, Abrahamson J, Barlow A, Daly MJ, Lincoln SE, Newburg L. MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics. 1987;1:174-181.
15. Lincoln SE, Lander ES. Systematic detection of errors in genetic linkage data. Genomics. 1992;14:604-610.
16. Lander ES, Botstein D. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics. 1989;121:185-189.
17. Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet. 1995;11:241-247.
18. Schork NJ, Krieger JE, Trolliet MR, Franchini KG, Korke G, Krieger EM, Lander ES, Dzau DJ, Jacob HJ. A biometrical genome search in rats reveals the multigenic basis of blood pressure variation. Genome Res. 1995;5:164-172.
19. Turner ME, Johnson ML, Ely DL. Separate sex-influenced and genetic components in spontaneously hypertensive rat hypertension. Hypertension. 1991;17:1097-1103.
20. Ely DL, Falvo J, Dunphy G, Caplea A, Salisbury R, Turner M. The spontaneously hypertensive rat Y chromosome produces an early testosterone rise in normotensive rats. J Hypertens. 1994;12:769-774.
21. Deng AY, Rapp JP. Cosegregation of blood pressure with angiotensin converting enzyme and atrial natriuretic peptide receptor genes using Dahl salt-sensitive rats. Nat Genet. 1992;1:267-272.
22. Deng AY, Dene H, Rapp JP. Mapping of a quantitative trait locus for blood pressure on rat chromosome 2. J Clin Invest. 1994;94:431-436.
23. Dubay C, Vincent M, Samani NJ, Hilbert P, Kaiser MA, Beressi JP, Kotelevtsev Y, Beckmann JS, Soubrier F, Sassard J, Lathrop GM. Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats. Nat Genet. 1993;3:354-357.
24. Nara Y, Ikeda K, Mashimo T, Tamada T, Matsumoto T, Koh M, Sawamura M, Nabika T, Yamori Y. A new candidate locus for basal high blood pressure in male and female stroke-prone SHR (SHRSP/ Izm). J Hypertens. 1996;14(Suppl 1):511.Abstract.
25. Nabika T, Nara Y, Ikeda K, Endo J, Yamori Y. Genetic heterogeneity of the spontaneously hypertensive rat. Hypertension. 1991;18:12-16.
26. Melo JA, Shendure J, Pociesk K, Silver LM. Identification of sex-specific quantitative trait loci controlling alcohol preference in C57BL/6 mice. Nat Genet. 1996;13:147-153.
27. Swain JL, Stewart TA, Leder P. Parental legacy determines methylation and expression of an autosomal transgene: a molecular mechanism of parental imprinting. Cell. 1987;50:719-727.
28. Pravenec M, Gauguier D, Schott JJ, Buard J, Kren V, Bila V, Szpirer C, Szpirer J, Wang JM, Huang H, St Lezin E, Spence MA, Flodman P, Printz M, Lathrop GM, Vergnaud G, Kurtz TW. Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome screening of recombinant inbred strains. J Clin Invest. 1995; 96:1973-1978.
29. Brown DM, Provost AP, Daly MJ, Lauder ES, Jacob HJ. Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat. Nat Genet. 1996;12:44-51.
30. Rapp JP, Deng AY. Detection and positional cloning of blood pressure quantitative trait loci: is it possible? Identifying the genes for genetic hypertension. Hypertension. 1995;25:1121-1128.