Polymorphism of the NADH/NADPH oxidase p22 phox gene in patients with coronary artery disease

Circulation

Volumn 97, Issue 2, 1998, Pages 135-137

  Inoue, Nobutaka ^b   Kawashima, Seinosuke ^a   Kanazawa, Kenji ^b   Yamada, Shinichiro ^b   Akita, Hozuka ^b   Yokoyama, Mitsuhiro ^b  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

Coronary disease; Free radicals; Genes; Risk factors; Stress

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENETIC MARKER; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR;

EID: 0031940241     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.97.2.135     Document Type: Article

References (8)

1. Alexander RW. Hypertension and the pathogenesis of atherosclerosis: oxidative stress and the mediation of arterial inflammatory response: a new perspective, Hypertension. 1995;25:155-161.
2. Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994;74:1141-1148.
3. Mohazzab-H KM, Kaminski PM, Wolin MS. NADH oxidoreductase is a major source of Superoxide anion in bovine coronary artery endothelium. Am J Physiol. 1994;266:H2568-H2578.
4. Ushio-Fukai M, Zafari AM, Fukui T, Ishizaka N, Griendling KK. p22 phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol Client 1996;271:23317-23321.
5. Dinauer MC, Pierce EA, Bruns GAP, Curnutte JT, Orkin SH. Human neutrophil cytochrome b light chain (p22-phox): gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. J Clin Invest. 1990;86:1729-1737.
6. de Boer M, de Klein A, Hossle J-P, Seger R, Corbeel L, Weening RS, Roos D. Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b 558 light chain of the NADPH oxidase (p22-phox) Am J Hum Genet. 1992;51:1127-1135.
7. Jones SA, O'Donnell VB, Wood JD, Broughton JP, Hughes EJ, Jones OTG. Expression of phagocyte NADPH oxidase components in human endothelial cells. Am J Physiol. 1996;271:H1626-H1634.
8. Parkos CA, Dinauer MC, Walker LE, Allen RA, Jesaitis AJ, Orkin SH. Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b. Proc Natl Acad U S A. 1988;85: 3319-3323.