-
1
-
-
0031951973
-
Meta-analysis of linkage data under worst-case conditions: A demonstration using the human OB region
-
Allison DB, Heo M (1998) Meta-analysis of linkage data under worst-case conditions: a demonstration using the human OB region. Genetics 148:859-865
-
(1998)
Genetics
, vol.148
, pp. 859-865
-
-
Allison, D.B.1
Heo, M.2
-
3
-
-
0036208832
-
Patterns of linkage disequilibrium in the human genome
-
Ardlie KG, Kruglyak L, Seielstad M (2002) Patterns of linkage disequilibrium in the human genome. Nat Rev Genet 3:299-309
-
(2002)
Nat Rev Genet
, vol.3
, pp. 299-309
-
-
Ardlie, K.G.1
Kruglyak, L.2
Seielstad, M.3
-
4
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc Ser B 57:289-300
-
(1995)
J Roy Stat Soc Ser B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
5
-
-
0346882609
-
SNP subset selection for genetic association studies
-
Byng MC, Whittaker JC, Cuthbert AP, Mathew CG, Lewis CM (2003) SNP subset selection for genetic association studies. Ann Hum Genet 67:543-556
-
(2003)
Ann Hum Genet
, vol.67
, pp. 543-556
-
-
Byng, M.C.1
Whittaker, J.C.2
Cuthbert, A.P.3
Mathew, C.G.4
Lewis, C.M.5
-
6
-
-
0035257236
-
Association study designs for complex diseases
-
Cardon LR, Bell JI (2001) Association study designs for complex diseases. Nat Rev Genet 2:91-99
-
(2001)
Nat Rev Genet
, vol.2
, pp. 91-99
-
-
Cardon, L.R.1
Bell, J.I.2
-
7
-
-
84984932946
-
Population genetics: Making sense out of sequence
-
Chakravarti A (1999) Population genetics: making sense out of sequence. Nat Genet Suppl 21:56-60
-
(1999)
Nat Genet Suppl
, vol.21
, pp. 56-60
-
-
Chakravarti, A.1
-
8
-
-
0344033602
-
Detecting disease associations due to linkage disequilibrium using haplotype tags: A class of tests and the determinants of statistical power
-
Chapman JM, Cooper JD, Todd JA, Clayton DG (2003) Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power. Hum Hered 56:18-31
-
(2003)
Hum Hered
, vol.56
, pp. 18-31
-
-
Chapman, J.M.1
Cooper, J.D.2
Todd, J.A.3
Clayton, D.G.4
-
9
-
-
0035922669
-
Epidemiological methods for studying genes and environmental factors in complex diseases
-
Clayton D, McKeigue PM (2001) Epidemiological methods for studying genes and environmental factors in complex diseases. Lancet 358:1356-1360
-
(2001)
Lancet
, vol.358
, pp. 1356-1360
-
-
Clayton, D.1
McKeigue, P.M.2
-
10
-
-
0037426052
-
Problems of reporting genetic associations with complex outcomes
-
Colhoun HM, McKeigue PM, Davey Smith G (2003) Problems of reporting genetic associations with complex outcomes. Lancet 361:865-872
-
(2003)
Lancet
, vol.361
, pp. 865-872
-
-
Colhoun, H.M.1
McKeigue, P.M.2
Davey Smith, G.3
-
11
-
-
0030688004
-
Variations on a theme: Cataloguing human DNA sequence variation
-
Collins FS, Guyer MS, Charkravarti A (1997) Variations on a theme: cataloguing human DNA sequence variation. Science 278:1580-1581
-
(1997)
Science
, vol.278
, pp. 1580-1581
-
-
Collins, F.S.1
Guyer, M.S.2
Charkravarti, A.3
-
12
-
-
0037165976
-
Genomics: New mapping project splits the community
-
Couzin J (2002) Genomics: new mapping project splits the community. Science 296:1391-1393
-
(2002)
Science
, vol.296
, pp. 1391-1393
-
-
Couzin, J.1
-
13
-
-
1842435261
-
Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations
-
Crawford DC, Carlson CS, Rieder MJ, Carrington DP, Yi Q, Smith JD, Eberle MA, Kruglyak L, Nickerson DA (2004) Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations. Am J Hum Genet 74:610-622
-
(2004)
Am J Hum Genet
, vol.74
, pp. 610-622
-
-
Crawford, D.C.1
Carlson, C.S.2
Rieder, M.J.3
Carrington, D.P.4
Yi, Q.5
Smith, J.D.6
Eberle, M.A.7
Kruglyak, L.8
Nickerson, D.A.9
-
14
-
-
0034791035
-
High-resolution haplotype structure in the human genome
-
Daly MJ, Rioux JD, Schaffner SF, Hudson TJ, Lander ES (2001) High-resolution haplotype structure in the human genome. Nat Genet 29:229-232
-
(2001)
Nat Genet
, vol.29
, pp. 229-232
-
-
Daly, M.J.1
Rioux, J.D.2
Schaffner, S.F.3
Hudson, T.J.4
Lander, E.S.5
-
16
-
-
12144285594
-
Assessing the impact of population stratification on genetic association studies
-
Freedman ML, Reich D, Penney KL, McDonald GJ, Mignault AA, Patterson N, Gabriel SB, Topol EJ, Smoller JW, Pato CN, Pato MT, Petryshen TL, Kolonel LN, Lander ES, Sklar P, Henderson B, Hirschhorn JN, Altshuler D (2004) Assessing the impact of population stratification on genetic association studies. Nat Genet 36:388-393
-
(2004)
Nat Genet
, vol.36
, pp. 388-393
-
-
Freedman, M.L.1
Reich, D.2
Penney, K.L.3
McDonald, G.J.4
Mignault, A.A.5
Patterson, N.6
Gabriel, S.B.7
Topol, E.J.8
Smoller, J.W.9
Pato, C.N.10
Pato, M.T.11
Petryshen, T.L.12
Kolonel, L.N.13
Lander, E.S.14
Sklar, P.15
Henderson, B.16
Hirschhorn, J.N.17
Altshuler, D.18
-
17
-
-
18444369013
-
The structure of haplotype blocks in the human genome
-
Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D (2002) The structure of haplotype blocks in the human genome. Science 296:2225-2229
-
(2002)
Science
, vol.296
, pp. 2225-2229
-
-
Gabriel, S.B.1
Schaffner, S.F.2
Nguyen, H.3
Moore, J.M.4
Roy, J.5
Blumenstiel, B.6
Higgins, J.7
DeFelice, M.8
Lochner, A.9
Faggart, M.10
Liu-Cordero, S.N.11
Rotimi, C.12
Adeyemo, A.13
Cooper, R.14
Ward, R.15
Lander, E.S.16
Daly, M.J.17
Altshuler, D.18
-
18
-
-
85030828808
-
Power and sample size estimation in high dimensional biology
-
in press
-
Gadbury GL, Page GP, Edwards J, Kayo T, Prolla TA, Weindruch R, Permana PA, Mountz J, Allison DB. Power and sample size estimation in high dimensional biology. Stat Meth Med Res (in press)
-
Stat Meth Med Res
-
-
Gadbury, G.L.1
Page, G.P.2
Edwards, J.3
Kayo, T.4
Prolla, T.A.5
Weindruch, R.6
Permana, P.A.7
Mountz, J.8
Allison, D.B.9
-
19
-
-
0026609541
-
Distribution of ADH2 and ALDH2 genotypes in different populations
-
Goedde HW, Agarwal DP, Fritze G, Meier-Tackmann D, Singh S, Beckman G, Bhatia K, Chen LZ (1992) Distribution of ADH2 and ALDH2 genotypes in different populations. Hum Genet 88:344-346
-
(1992)
Hum Genet
, vol.88
, pp. 344-346
-
-
Goedde, H.W.1
Agarwal, D.P.2
Fritze, G.3
Meier-Tackmann, D.4
Singh, S.5
Beckman, G.6
Bhatia, K.7
Chen, L.Z.8
-
20
-
-
0025893282
-
Empirical-Bayes adjustments for multiple comparisons are sometimes useful
-
Greenland S, Robins JM (1991) Empirical-Bayes adjustments for multiple comparisons are sometimes useful. Epidemiology 2:244-251
-
(1991)
Epidemiology
, vol.2
, pp. 244-251
-
-
Greenland, S.1
Robins, J.M.2
-
21
-
-
0005350530
-
Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese
-
Harada S, Agarwal DP, Goedde HW (1981) Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese. Lancet 2:982
-
(1981)
Lancet
, vol.2
, pp. 982
-
-
Harada, S.1
Agarwal, D.P.2
Goedde, H.W.3
-
22
-
-
0035958749
-
Genome research: Map of the human genome 3.0
-
Helmuth L (2001) Genome research: map of the human genome 3.0. Science 293:583-585
-
(2001)
Science
, vol.293
, pp. 583-585
-
-
Helmuth, L.1
-
24
-
-
0038813649
-
Genetic associations: False or true?
-
Ioannidis JP (2003) Genetic associations: false or true? Trends Mol Med 9:135-138
-
(2003)
Trends Mol Med
, vol.9
, pp. 135-138
-
-
Ioannidis, J.P.1
-
26
-
-
0034789532
-
Haplotype tagging for the identification of common disease genes
-
Johnson GC, Esposito L, Barratt BJ, Smith AN, Heward J, Di Genova G, Ueda H, Cordell HJ, Eaves IA, Dudbridge F, Twells RC, Payne F, Hughes W, Nutland S, Stevens H, Carr P, Tuomilehto-Wolf E, Tuomilehto J, Gough SC, Clayton DG, Todd JA (2001) Haplotype tagging for the identification of common disease genes. Nat Genet 29:233-237
-
(2001)
Nat Genet
, vol.29
, pp. 233-237
-
-
Johnson, G.C.1
Esposito, L.2
Barratt, B.J.3
Smith, A.N.4
Heward, J.5
Di Genova, G.6
Ueda, H.7
Cordell, H.J.8
Eaves, I.A.9
Dudbridge, F.10
Twells, R.C.11
Payne, F.12
Hughes, W.13
Nutland, S.14
Stevens, H.15
Carr, P.16
Tuomilehto-Wolf, E.17
Tuomilehto, J.18
Gough, S.C.19
Clayton, D.G.20
Todd, J.A.21
more..
-
27
-
-
0028877463
-
Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
-
Lander E, Kruglyak L (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247
-
(1995)
Nat Genet
, vol.11
, pp. 241-247
-
-
Lander, E.1
Kruglyak, L.2
-
28
-
-
0028090414
-
Genetic dissection of complex traits
-
Lander ES, Schork NJ (1994) Genetic dissection of complex traits. Science 265:2037-2048
-
(1994)
Science
, vol.265
, pp. 2037-2048
-
-
Lander, E.S.1
Schork, N.J.2
-
29
-
-
0036597746
-
Genetic association studies: Design, analysis and interpretation
-
Lewis CM (2002) Genetic association studies: design, analysis and interpretation. Brief Bioinform 3:146-153
-
(2002)
Brief Bioinform
, vol.3
, pp. 146-153
-
-
Lewis, C.M.1
-
30
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33:177-182
-
(2003)
Nat Genet
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
-
31
-
-
3242768295
-
Cost-effective analysis of candidate genes using htSNPs: A staged approach
-
Lowe CE, Cooper JD, Chapman JM, Barratt BJ, Twells RC, Green EA, Savage DA, Guja C, Ionescu-Tirgoviste C, Tuomilehto-Wolf E, Tuomilehto J, Todd JA, Clayton DG (2004) Cost-effective analysis of candidate genes using htSNPs: a staged approach. Genes Immun 5:301-305
-
(2004)
Genes Immun
, vol.5
, pp. 301-305
-
-
Lowe, C.E.1
Cooper, J.D.2
Chapman, J.M.3
Barratt, B.J.4
Twells, R.C.5
Green, E.A.6
Savage, D.A.7
Guja, C.8
Ionescu-Tirgoviste, C.9
Tuomilehto-Wolf, E.10
Tuomilehto, J.11
Todd, J.A.12
Clayton, D.G.13
-
32
-
-
0037395091
-
No evidence for association of the dysbindin gene [DTNBP1] with schizophrenia in an Irish population-based study
-
Morris DW, McGhee KA, Schwaiger S, Scully P, Quinn J, Meagher D, Waddington JL, Gill M, Corvin AP (2003) No evidence for association of the dysbindin gene [DTNBP1] with schizophrenia in an Irish population-based study. Schizophr Res 60:167-172
-
(2003)
Schizophr Res
, vol.60
, pp. 167-172
-
-
Morris, D.W.1
McGhee, K.A.2
Schwaiger, S.3
Scully, P.4
Quinn, J.5
Meagher, D.6
Waddington, J.L.7
Gill, M.8
Corvin, A.P.9
-
33
-
-
0043048571
-
Sequential tests for the detection of linkage
-
Morton NE (1955) Sequential tests for the detection of linkage. Am J Hum Genet 7:277-318
-
(1955)
Am J Hum Genet
, vol.7
, pp. 277-318
-
-
Morton, N.E.1
-
34
-
-
0032530165
-
Tests and estimates of allelic association in complex inheritance
-
Morton NE, Collins A (1998) Tests and estimates of allelic association in complex inheritance. Proc Natl Acad Sci USA 95:11389-11393
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11389-11393
-
-
Morton, N.E.1
Collins, A.2
-
35
-
-
0031594566
-
Association of the ADH2*2 allele with reduced ethanol consumption in Jewish men in Israel: A pilot study
-
Neumark YD, Friedlander Y, Thomasson HR, Li T-K (1998) Association of the ADH2*2 allele with reduced ethanol consumption in Jewish men in Israel: a pilot study. J Stud Alcohol 59:133-139
-
(1998)
J Stud Alcohol
, vol.59
, pp. 133-139
-
-
Neumark, Y.D.1
Friedlander, Y.2
Thomasson, H.R.3
Li, T.-K.4
-
36
-
-
1542330229
-
Assessing optimal neural network architecture for identifying disease-associated multi-marker genotypes using a permutation test, and application to calpain 10 polymorphisms associated with diabetes
-
North BV, Curtis D, Cassell PG, Hitman GA, Sham PC (2003) Assessing optimal neural network architecture for identifying disease-associated multi-marker genotypes using a permutation test, and application to calpain 10 polymorphisms associated with diabetes. Ann Hum Genet 67:348-356
-
(2003)
Ann Hum Genet
, vol.67
, pp. 348-356
-
-
North, B.V.1
Curtis, D.2
Cassell, P.G.3
Hitman, G.A.4
Sham, P.C.5
-
37
-
-
18444412585
-
A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity
-
Osier MV, Pakstis AJ, Soodyall H, Comas D, Goldman D, Odunsi A, Okonofua F, Parnas J, Schulz LO, Bertranpetit J, Bonne-Tamir B, Lu R-B, Kidd JR, Kidd KK (2002) A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am J Hum Genet 71:84-99
-
(2002)
Am J Hum Genet
, vol.71
, pp. 84-99
-
-
Osier, M.V.1
Pakstis, A.J.2
Soodyall, H.3
Comas, D.4
Goldman, D.5
Odunsi, A.6
Okonofua, F.7
Parnas, J.8
Schulz, L.O.9
Bertranpetit, J.10
Bonne-Tamir, B.11
Lu, R.-B.12
Kidd, J.R.13
Kidd, K.K.14
-
38
-
-
0142059667
-
"Are we there yet?": Deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits
-
Page GP, George V, Go RC, Page PZ, Allison DB (2003) "Are we there yet?": deciding when one has demonstrated specific genetic causation in complex diseases and quantitative traits. Am J Hum Genet 73:711-719
-
(2003)
Am J Hum Genet
, vol.73
, pp. 711-719
-
-
Page, G.P.1
George, V.2
Go, R.C.3
Page, P.Z.4
Allison, D.B.5
-
39
-
-
0035941029
-
Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21
-
Patil N, Berno AJ, Hinds DA, Barrett WA, Doshi JM, Hacker CR, Kautzer CR, Lee DH, Marjoribanks C, McDonough DP, Nguyen BT, Norris MC, Sheehan JB, Shen N, Stern D, Stokowski RP, Thomas DJ, Trulson MO, Vyas KR, Frazer KA, Fodor SP, Cox DR (2001) Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science 294:1719-1723
-
(2001)
Science
, vol.294
, pp. 1719-1723
-
-
Patil, N.1
Berno, A.J.2
Hinds, D.A.3
Barrett, W.A.4
Doshi, J.M.5
Hacker, C.R.6
Kautzer, C.R.7
Lee, D.H.8
Marjoribanks, C.9
McDonough, D.P.10
Nguyen, B.T.11
Norris, M.C.12
Sheehan, J.B.13
Shen, N.14
Stern, D.15
Stokowski, R.P.16
Thomas, D.J.17
Trulson, M.O.18
Vyas, K.R.19
Frazer, K.A.20
Fodor, S.P.21
Cox, D.R.22
more..
-
40
-
-
0033007695
-
Nucleotide sequence diversity in non-coding regions of ALDH2 as revealed by restriction enzyme and SSCP analysis
-
Peterson RJ, Goldman D, Long JC (1999) Nucleotide sequence diversity in non-coding regions of ALDH2 as revealed by restriction enzyme and SSCP analysis. Hum Genet 104:177-187
-
(1999)
Hum Genet
, vol.104
, pp. 177-187
-
-
Peterson, R.J.1
Goldman, D.2
Long, J.C.3
-
41
-
-
0034969437
-
Are rare variants responsible for susceptibility to complex diseases?
-
Pritchard JK (2001) Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet 69:124-137
-
(2001)
Am J Hum Genet
, vol.69
, pp. 124-137
-
-
Pritchard, J.K.1
-
42
-
-
0034977045
-
Linkage disequilibrium in humans: Models and data
-
Pritchard JK, Przeworski M (2001) Linkage disequilibrium in humans: models and data. Am J Hum Genet 69:1-14
-
(2001)
Am J Hum Genet
, vol.69
, pp. 1-14
-
-
Pritchard, J.K.1
Przeworski, M.2
-
44
-
-
0035451780
-
On the allelic spectrum of human disease
-
Reich DE, Lander ES (2001) On the allelic spectrum of human disease. Trends Genet 17:502-510
-
(2001)
Trends Genet
, vol.17
, pp. 502-510
-
-
Reich, D.E.1
Lander, E.S.2
-
45
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N, Merikangas K (1996) The future of genetic studies of complex human diseases. Science 273:1516-1517
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
46
-
-
0034660559
-
Searching for genetic determinants in the new millennium
-
Risch NJ (2000) Searching for genetic determinants in the new millennium. Nature 405:847-856
-
(2000)
Nature
, vol.405
, pp. 847-856
-
-
Risch, N.J.1
-
47
-
-
0036155283
-
Score tests for association between traits and haplotypes when linkage phase is ambiguous
-
Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA (2002) Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70:425-434
-
(2002)
Am J Hum Genet
, vol.70
, pp. 425-434
-
-
Schaid, D.J.1
Rowland, C.M.2
Tines, D.E.3
Jacobson, R.M.4
Poland, G.A.5
-
48
-
-
0033810469
-
Single nucleotide polymorphisms and the future of genetic epidemiology
-
Schork NJ, Fallin D, Lanchbury JS (2000) Single nucleotide polymorphisms and the future of genetic epidemiology. Clin Genet 58:250-264
-
(2000)
Clin Genet
, vol.58
, pp. 250-264
-
-
Schork, N.J.1
Fallin, D.2
Lanchbury, J.S.3
-
49
-
-
0037222276
-
Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families
-
Schwab SG, Knapp M, Mondabon S, Hallmayer J, Borrmann-Hassenbach M, Albus M, Lerer B, Rietschel M, Trixler M, Maier W, Wildenauer DB (2003) Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families. Am J Hum Genet 72:185-190
-
(2003)
Am J Hum Genet
, vol.72
, pp. 185-190
-
-
Schwab, S.G.1
Knapp, M.2
Mondabon, S.3
Hallmayer, J.4
Borrmann-Hassenbach, M.5
Albus, M.6
Lerer, B.7
Rietschel, M.8
Trixler, M.9
Maier, W.10
Wildenauer, D.B.11
-
50
-
-
0038449167
-
Evolutionary-based association analysis using haplotype data
-
Seltman H, Roeder K, Devlin B (2003) Evolutionary-based association analysis using haplotype data. Genet Epidemiol 25:48-58
-
(2003)
Genet Epidemiol
, vol.25
, pp. 48-58
-
-
Seltman, H.1
Roeder, K.2
Devlin, B.3
-
51
-
-
0036844881
-
DNA pooling: A tool for large-scale association studies
-
Sham P, Bader JS, Craig I, O'Donovan M, Owen M (2002) DNA Pooling: a tool for large-scale association studies. Nat Rev Genet 3:862-871
-
(2002)
Nat Rev Genet
, vol.3
, pp. 862-871
-
-
Sham, P.1
Bader, J.S.2
Craig, I.3
O'Donovan, M.4
Owen, M.5
-
52
-
-
1442332571
-
Haplotype association analysis of discrete and continuous traits using mixture of regression models
-
Sham PC, Rijsdijk FV, Knight J, Makoff A, North B, Curtis D (2004) Haplotype association analysis of discrete and continuous traits using mixture of regression models. Behav Genet 34:207-214
-
(2004)
Behav Genet
, vol.34
, pp. 207-214
-
-
Sham, P.C.1
Rijsdijk, F.V.2
Knight, J.3
Makoff, A.4
North, B.5
Curtis, D.6
-
53
-
-
0033915978
-
The effect of marker characteristics on the power to detect linkage disequilibrium due to single or multiple ancestral mutations
-
Sham PC, Zhao JH, Curtis D (2000) The effect of marker characteristics on the power to detect linkage disequilibrium due to single or multiple ancestral mutations. Ann Hum Genet 64:161-169
-
(2000)
Ann Hum Genet
, vol.64
, pp. 161-169
-
-
Sham, P.C.1
Zhao, J.H.2
Curtis, D.3
-
55
-
-
0027377799
-
Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
-
Spielman RS, McGinnis RE, Ewens WJ (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516
-
(1993)
Am J Hum Genet
, vol.52
, pp. 506-516
-
-
Spielman, R.S.1
McGinnis, R.E.2
Ewens, W.J.3
-
56
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey JD, Tibshirani R (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci USA 100:9440-9445
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
57
-
-
18444364206
-
Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia
-
Straub RE, Jiang Y, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, O'Neill FA, Walsh D, Kendler KS (2002) Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia. Am J Hum Genet 71:337-348
-
(2002)
Am J Hum Genet
, vol.71
, pp. 337-348
-
-
Straub, R.E.1
Jiang, Y.2
MacLean, C.J.3
Ma, Y.4
Webb, B.T.5
Myakishev, M.V.6
Harris-Kerr, C.7
Wormley, B.8
Sadek, H.9
Kadambi, B.10
O'Neill, F.A.11
Walsh, D.12
Kendler, K.S.13
-
58
-
-
0037425607
-
Demography, recombination hotspot intensity, and the block structure of linkage disequilibrium
-
Stumpf MP, Goldstein DB (2003) Demography, recombination hotspot intensity, and the block structure of linkage disequilibrium. Curr Biol 13:1-8
-
(2003)
Curr Biol
, vol.13
, pp. 1-8
-
-
Stumpf, M.P.1
Goldstein, D.B.2
-
59
-
-
0141993288
-
Estimation of multilocus haplotype effects using weighted penalised log-likelihood: Analysis of five sequence variations at the cholesteryl ester transfer protein gene locus
-
Tanck MW, Klerkx AH, Jukema JW, De Knijff P, Kastelein JJ, Zwinderman AH (2003) Estimation of multilocus haplotype effects using weighted penalised log-likelihood: analysis of five sequence variations at the cholesteryl ester transfer protein gene locus. Ann Hum Genet 67:175-184
-
(2003)
Ann Hum Genet
, vol.67
, pp. 175-184
-
-
Tanck, M.W.1
Klerkx, A.H.2
Jukema, J.W.3
De Knijff, P.4
Kastelein, J.J.5
Zwinderman, A.H.6
-
60
-
-
0032403973
-
Linkage disequilibrium mapping of complex disease: Fantasy or reality?
-
Terwilliger JD, Weiss KM (1998) Linkage disequilibrium mapping of complex disease: fantasy or reality? Curr Opin Biotechnol 9:578-594
-
(1998)
Curr Opin Biotechnol
, vol.9
, pp. 578-594
-
-
Terwilliger, J.D.1
Weiss, K.M.2
-
62
-
-
0344395013
-
Bayesian spatial modeling of haplotype associations
-
Thomas DC, Stram DO, Conti D, Molitor J, Marjoram P (2003) Bayesian spatial modeling of haplotype associations. Hum Hered 56:32-40
-
(2003)
Hum Hered
, vol.56
, pp. 32-40
-
-
Thomas, D.C.1
Stram, D.O.2
Conti, D.3
Molitor, J.4
Marjoram, P.5
-
63
-
-
0036277684
-
Point: Population stratification: A problem for case-control studies of candidate-gene associations?
-
Thomas DC, Witte JS (2002) Point: population stratification: a problem for case-control studies of candidate-gene associations? Cancer Epidemiol Biomarkers Prev 11:505-512
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 505-512
-
-
Thomas, D.C.1
Witte, J.S.2
-
64
-
-
0028278450
-
Low frequency of the ADH2*2 allele among Atayal natives of Taiwan with alcohol use disorders
-
Thomasson HR, Crabb DW, Edenberg HJ, Li T-K, Hwu H-G, Chen C-C, Yeh E-K, Yin S-J (1994) Low frequency of the ADH2*2 allele among Atayal natives of Taiwan with alcohol use disorders. Alcohol Clin Exp Res 18:640-643
-
(1994)
Alcohol Clin Exp Res
, vol.18
, pp. 640-643
-
-
Thomasson, H.R.1
Crabb, D.W.2
Edenberg, H.J.3
Li, T.-K.4
Hwu, H.-G.5
Chen, C.-C.6
Yeh, E.-K.7
Yin, S.-J.8
-
65
-
-
9144267763
-
The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease
-
Van Den Bogaett A, Schumacher J, Schulze TG, Otte AC, Ohlraun S, Kovalenko S, Becker T, Fteudenberg J, Jönsson EG, Mattila-Evenden M, Sedvall GC, Czerski PM, Kapelski P, Hauser J, Maier W, Rietschel M, Propping P, Nöthen MM, Cichon S (2003) The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease. Am J Hum Genet 73:1438-1443
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1438-1443
-
-
Van Den Bogaett, A.1
Schumacher, J.2
Schulze, T.G.3
Otte, A.C.4
Ohlraun, S.5
Kovalenko, S.6
Becker, T.7
Fteudenberg, J.8
Jönsson, E.G.9
Mattila-Evenden, M.10
Sedvall, G.C.11
Czerski, P.M.12
Kapelski, P.13
Hauser, J.14
Maier, W.15
Rietschel, M.16
Propping, P.17
Nöthen, M.M.18
Cichon, S.19
-
66
-
-
1942534046
-
Will baplotype maps be useful for finding genes?
-
van den Oord EJ, Neale BM (2003) Will baplotype maps be useful for finding genes? Mol Psychiatry 9:227-236
-
(2003)
Mol Psychiatry
, vol.9
, pp. 227-236
-
-
Van Den Oord, E.J.1
Neale, B.M.2
-
67
-
-
0141450364
-
False discoveries and models for gene discovery
-
van den Oord EJ, Sullivan PF (2003) False discoveries and models for gene discovery. Trends Genet 19:537-542
-
(2003)
Trends Genet
, vol.19
, pp. 537-542
-
-
Van Den Oord, E.J.1
Sullivan, P.F.2
-
68
-
-
1642295096
-
Assessing the probability of false-positive reports in molecular epidemiology studies
-
Wacholder S, Chanock S, Garcia-Closas M, Elghormli L, Rothman N (2004) Assessing the probability of false-positive reports in molecular epidemiology studies. J Natl Cancer Inst 96:434-442
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 434-442
-
-
Wacholder, S.1
Chanock, S.2
Garcia-Closas, M.3
Elghormli, L.4
Rothman, N.5
-
69
-
-
0042387804
-
Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCNIA: Implications for linkage-disequilibrium gene mapping
-
Weale ME, Depondt C, Macdonald SJ, Smith A, Lai PS, Shorvon SD, Wood NW, Goldstein DB (2003) Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCNIA: implications for linkage-disequilibrium gene mapping. Am J Hum Genet 73:551-565
-
(2003)
Am J Hum Genet
, vol.73
, pp. 551-565
-
-
Weale, M.E.1
Depondt, C.2
Macdonald, S.J.3
Smith, A.4
Lai, P.S.5
Shorvon, S.D.6
Wood, N.W.7
Goldstein, D.B.8
-
70
-
-
0036137130
-
Linkage disequilibrium and the mapping of complex human traits
-
Weiss KM, Clark AG (2002) Linkage disequilibrium and the mapping of complex human traits. Trends Genet 18:19-24
-
(2002)
Trends Genet
, vol.18
, pp. 19-24
-
-
Weiss, K.M.1
Clark, A.G.2
-
71
-
-
11144356974
-
Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1)
-
Williams NM, Preece A, Morris DW, Spurlock G, Bray NJ, Stephens M, Norton N, Williams H, Clement M, Dwyer S, Curran C, Wilkinson J, Moskvina V, Waddington JL, Gill M, Corvin AP, Zammit S, Kirov G, Owen MJ, O'Donovan MC (2004) Identification in 2 independent samples of a novel schizophrenia risk haplotype of the dystrobrevin binding protein gene (DTNBP1). Arch Gen Psychiatry 61:336-344
-
(2004)
Arch Gen Psychiatry
, vol.61
, pp. 336-344
-
-
Williams, N.M.1
Preece, A.2
Morris, D.W.3
Spurlock, G.4
Bray, N.J.5
Stephens, M.6
Norton, N.7
Williams, H.8
Clement, M.9
Dwyer, S.10
Curran, C.11
Wilkinson, J.12
Moskvina, V.13
Waddington, J.L.14
Gill, M.15
Corvin, A.P.16
Zammit, S.17
Kirov, G.18
Owen, M.J.19
O'Donovan, M.C.20
more..
-
72
-
-
0036284203
-
Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals
-
Zaykin DV, Westfall PH, Young SS, Katnoub MA, Wagner MJ, Ehm MG (2002) Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals. Hum Hered 53:79-91
-
(2002)
Hum Hered
, vol.53
, pp. 79-91
-
-
Zaykin, D.V.1
Westfall, P.H.2
Young, S.S.3
Katnoub, M.A.4
Wagner, M.J.5
Ehm, M.G.6
-
73
-
-
0036918575
-
Haplotype block structure and its applications to association studies: Power and study designs
-
Zhang K, Calabrese P, Nordborg M, Sun F (2002a) Haplotype block structure and its applications to association studies: power and study designs. Am J Hum Genet 71:1386-1394
-
(2002)
Am J Hum Genet
, vol.71
, pp. 1386-1394
-
-
Zhang, K.1
Calabrese, P.2
Nordborg, M.3
Sun, F.4
-
74
-
-
2442658957
-
Haplotype block partitioning and tag SNP selection using genotype data and their applications to association studies
-
Zhang K, Qin ZS, Liu JS, Chen T, Waterman MS, Sun F (2004) Haplotype block partitioning and tag SNP selection using genotype data and their applications to association studies. Genome Res 14:908-916
-
(2004)
Genome Res
, vol.14
, pp. 908-916
-
-
Zhang, K.1
Qin, Z.S.2
Liu, J.S.3
Chen, T.4
Waterman, M.S.5
Sun, F.6
-
75
-
-
0041385677
-
Transmission/disequilibrium test based on haplotype sharing for rightly linked markers
-
Zhang S, Sha Q, Chen H-S, Dong J, Jiang R (2003) Transmission/ disequilibrium test based on haplotype sharing for rightly linked markers. Am J Hum Genet 73:566-579
-
(2003)
Am J Hum Genet
, vol.73
, pp. 566-579
-
-
Zhang, S.1
Sha, Q.2
Chen, H.-S.3
Dong, J.4
Jiang, R.5
-
76
-
-
0036563040
-
Mapping quantitative effects of oligogenes by allelic association
-
Zhang W, Collins A, Abecasis GR, Cardon LR, Morton NE (2002b) Mapping quantitative effects of oligogenes by allelic association. Ann Hum Genet 66:211-221
-
(2002)
Ann Hum Genet
, vol.66
, pp. 211-221
-
-
Zhang, W.1
Collins, A.2
Abecasis, G.R.3
Cardon, L.R.4
Morton, N.E.5
-
77
-
-
0038406155
-
A method for the assessment of disease associations with single-nucleotide polymorphism haplotypes and environmental variables in case-control studies
-
Zhao LP, Li SS, Khalid N (2003) A method for the assessment of disease associations with single-nucleotide polymorphism haplotypes and environmental variables in case-control studies. Am J Hum Genet 72:1231-1250
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1231-1250
-
-
Zhao, L.P.1
Li, S.S.2
Khalid, N.3
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