메뉴 건너뛰기




Volumn 24, Issue 18, 2004, Pages 8154-8166

Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages

Author keywords

[No Author keywords available]

Indexed keywords

26 HYDROXYCHOLESTEROL; CELL NUCLEUS RECEPTOR; CYTOCHROME P450; LIGAND; LIVER X RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RETINOIC ACID; RETINOID;

EID: 4444337443     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.18.8154-8166.2004     Document Type: Article
Times cited : (107)

References (49)
  • 1
    • 0024394549 scopus 로고
    • Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
    • Andersson, S., D. L. Davis, H. Dahlback, H. Jornvall, and D. W. Russell. 1989. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J. Biol. Chem. 264:8222-8229.
    • (1989) J. Biol. Chem. , vol.264 , pp. 8222-8229
    • Andersson, S.1    Davis, D.L.2    Dahlback, H.3    Jornvall, H.4    Russell, D.W.5
  • 2
    • 0032770376 scopus 로고    scopus 로고
    • Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: Evidence that most of this steroid in the circulation is of pulmonary origin
    • Babiker, A., O. Andersson, D. Lindblom, J. van der Linden, B. Wildund, D. Lutjohann, U. Diczfalusy, and I. Bjorkhem. 1999. Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: evidence that most of this steroid in the circulation is of pulmonary origin. J. Lipid Res. 40:1417-1425.
    • (1999) J. Lipid Res. , vol.40 , pp. 1417-1425
    • Babiker, A.1    Andersson, O.2    Lindblom, D.3    Van Der Linden, J.4    Wildund, B.5    Lutjohann, D.6    Diczfalusy, U.7    Bjorkhem, I.8
  • 3
    • 0030720329 scopus 로고    scopus 로고
    • Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport
    • Babiker, A., O. Andersson, E. Lund, R. J. Xiu, S. Deeb, A. Reshef, E. Leitersdorf, U. Diczfalusy, and I. Bjorkhem. 1997. Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport. J. Biol. Chem. 272:26253-26261.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26253-26261
    • Babiker, A.1    Andersson, O.2    Lund, E.3    Xiu, R.J.4    Deeb, S.5    Reshef, A.6    Leitersdorf, E.7    Diczfalusy, U.8    Bjorkhem, I.9
  • 4
    • 0242290172 scopus 로고    scopus 로고
    • Molecular determinants of the balance between co-repressor and co-activator recruitment to the retinoic acid receptor
    • Benko, S., J. D. Love, M. Beladi, J. W. Schwabe, and L. Nagy. 2003. Molecular determinants of the balance between co-repressor and co-activator recruitment to the retinoic acid receptor. J. Biol. Chem. 278:43797-43806.
    • (2003) J. Biol. Chem. , vol.278 , pp. 43797-43806
    • Benko, S.1    Love, J.D.2    Beladi, M.3    Schwabe, J.W.4    Nagy, L.5
  • 5
    • 0028068796 scopus 로고
    • Atherosclerosis and sterol 27-hydroxylase: Evidence for a role of this enzyme in elimination of cholesterol from human macrophages
    • Bjorkhem, I., O. Andersson, U. Diczfalusy, B. Sevastik, R. J. Xiu, C. Duan, and E. Lund. 1994. Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages. Proc. Natl. Acad. Sci. USA 91:8592-8596.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8592-8596
    • Bjorkhem, I.1    Andersson, O.2    Diczfalusy, U.3    Sevastik, B.4    Xiu, R.J.5    Duan, C.6    Lund, E.7
  • 6
    • 0343953577 scopus 로고    scopus 로고
    • Sterol 27-hydroxylase deficiency: A rare cause of xanthomas in normocholesterolemic humans
    • Bjorkhem, I., and E. Leitersdorf. 2000. Sterol 27-hydroxylase deficiency: a rare cause of xanthomas in normocholesterolemic humans. Trends Endocrinol. Metab. 11:180-183.
    • (2000) Trends Endocrinol. Metab. , vol.11 , pp. 180-183
    • Bjorkhem, I.1    Leitersdorf, E.2
  • 7
    • 0025914556 scopus 로고
    • Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis
    • Cali, J. J., C. L. Hsieh, U. Francke, and D. W. Russell. 1991. Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis. J. Biol. Chem. 266:7779-7783.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7779-7783
    • Cali, J.J.1    Hsieh, C.L.2    Francke, U.3    Russell, D.W.4
  • 8
    • 0025868097 scopus 로고
    • Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis
    • Cali, J. J., and D. W. Russell. 1991. Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis. J. Biol. Chem. 266:7774-7778.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7774-7778
    • Cali, J.J.1    Russell, D.W.2
  • 10
    • 0029097233 scopus 로고
    • A transcriptional co-repressor that interacts with nuclear hormone receptors
    • Chen, J. D., and R. M. Evans. 1995. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377:454-457.
    • (1995) Nature , vol.377 , pp. 454-457
    • Chen, J.D.1    Evans, R.M.2
  • 13
    • 0031576814 scopus 로고    scopus 로고
    • Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaques
    • Crisby, M., J. Nilsson, V. Kostulas, I. Bjorkhem, and U. Diczfalusy. 1997. Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaques. Biochim. Biophys. Acta 1344:278-285.
    • (1997) Biochim. Biophys. Acta , vol.1344 , pp. 278-285
    • Crisby, M.1    Nilsson, J.2    Kostulas, V.3    Bjorkhem, I.4    Diczfalusy, U.5
  • 14
    • 0021827570 scopus 로고
    • Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells
    • Davies, P. J., M. P. Murtaugh, W. T. Moore, Jr., G. S. Johnson, and D. Lucas. 1985. Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells. J. Biol. Chem. 260:5166-5174.
    • (1985) J. Biol. Chem. , vol.260 , pp. 5166-5174
    • Davies, P.J.1    Murtaugh, M.P.2    Moore Jr., W.T.3    Johnson, G.S.4    Lucas, D.5
  • 15
    • 0028816863 scopus 로고
    • Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry
    • Dzeletovic, S., O. Breuer, E. Lund, and U. Diczfalusy. 1995. Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry. Anal. Biochem. 225:73-80.
    • (1995) Anal. Biochem. , vol.225 , pp. 73-80
    • Dzeletovic, S.1    Breuer, O.2    Lund, E.3    Diczfalusy, U.4
  • 16
    • 0038175529 scopus 로고    scopus 로고
    • Expression of sterol 27-hydroxylase (CYP27A1) enhances cholesterol efflux
    • Escher, G., Z. Krozowski, K. D. Croft, and D. Sviridov. 2003. Expression of sterol 27-hydroxylase (CYP27A1) enhances cholesterol efflux. J. Biol. Chem. 278:11015-11019.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11015-11019
    • Escher, G.1    Krozowski, Z.2    Croft, K.D.3    Sviridov, D.4
  • 17
    • 0035914330 scopus 로고    scopus 로고
    • 27-Hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
    • Fu, X., J. G. Menke, Y. Chen, G. Zhou, K. L. MacNaul, S. D. Wright, C. P. Sparrow, and E. G. Lund. 2001. 27-Hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J. Biol. Chem. 276:38378-38387.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38378-38387
    • Fu, X.1    Menke, J.G.2    Chen, Y.3    Zhou, G.4    MacNaul, K.L.5    Wright, S.D.6    Sparrow, C.P.7    Lund, E.G.8
  • 18
    • 0037160511 scopus 로고    scopus 로고
    • Functional analysis of the promoter of human sterol 27-hydroxylase gene in HepG2 cells
    • Garuti, R., M. A. Croce, L. Piccinini, R. Tiozzo, S. Bertolini, and S. Calandra. 2002. Functional analysis of the promoter of human sterol 27-hydroxylase gene in HepG2 cells. Gene 283:133-143.
    • (2002) Gene , vol.283 , pp. 133-143
    • Garuti, R.1    Croce, M.A.2    Piccinini, L.3    Tiozzo, R.4    Bertolini, S.5    Calandra, S.6
  • 20
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis: The road ahead
    • Glass, C. K., and J. L. Witztum. 2001. Atherosclerosis: the road ahead. Cell 104:503-516.
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 21
    • 0026525053 scopus 로고
    • Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression
    • Graves, R. A., P. Tontonoz, and B. M. Spiegelman. 1992. Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression. Mol. Cell. Biol. 12:1202-1208.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1202-1208
    • Graves, R.A.1    Tontonoz, P.2    Spiegelman, B.M.3
  • 22
    • 12244297393 scopus 로고    scopus 로고
    • Marked induction of sterol 27-hydroxylase activity and mRNA levels during differentiation of human cultured monocytes into macrophages
    • Hansson, M., E. Ellis, M. C. Hunt, G. Schmitz, and A. Babiker. 2003. Marked induction of sterol 27-hydroxylase activity and mRNA levels during differentiation of human cultured monocytes into macrophages. Biochim. Biophys. Acta 1593:283-289.
    • (2003) Biochim. Biophys. Acta , vol.1593 , pp. 283-289
    • Hansson, M.1    Ellis, E.2    Hunt, M.C.3    Schmitz, G.4    Babiker, A.5
  • 23
    • 0030060474 scopus 로고    scopus 로고
    • Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages
    • Hulten, L. M., H. Lindmark, U. Diczfalusy, I. Bjorkhem, M. Ottosson, Y. Liu, G. Bondjers, and O. Wiklund. 1996. Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages. J. Clin. Investig. 97:461-468.
    • (1996) J. Clin. Investig. , vol.97 , pp. 461-468
    • Hulten, L.M.1    Lindmark, H.2    Diczfalusy, U.3    Bjorkhem, I.4    Ottosson, M.5    Liu, Y.6    Bondjers, G.7    Wiklund, O.8
  • 25
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
    • Janowski, B. A., P. J. Willy, T. R. Devi, J. R. Falck, and D. J. Mangelsdorf. 1996. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 383:728-731.
    • (1996) Nature , vol.383 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 26
    • 0347034082 scopus 로고    scopus 로고
    • Characterization of the human ABCG1 gene: Liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein
    • Kennedy, M. A., A. Venkateswaran, P. T. Tarr, I. Xenarios, J. Kudoh, N. Shimizu, and P. A. Edwards. 2001. Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. J. Biol. Chem. 276:39438-39447.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39438-39447
    • Kennedy, M.A.1    Venkateswaran, A.2    Tarr, P.T.3    Xenarios, I.4    Kudoh, J.5    Shimizu, N.6    Edwards, P.A.7
  • 27
    • 0033388858 scopus 로고    scopus 로고
    • In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment
    • Kuo, M. H., and C. D. Allis. 1999. In vivo cross-linking and immunoprecipitation for studying dynamic protein:DNA associations in a chromatin environment. Methods 19:425-433.
    • (1999) Methods , vol.19 , pp. 425-433
    • Kuo, M.H.1    Allis, C.D.2
  • 29
    • 0037372065 scopus 로고    scopus 로고
    • The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions
    • Laffitte, B. A., S. B. Joseph, M. Chen, A. Castrillo, J. Repa, D. Wilpitz, D. Mangelsdorf, and P. Tontonoz. 2003. The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions. Mol. Cell. Biol. 23:2182-2191.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2182-2191
    • Laffitte, B.A.1    Joseph, S.B.2    Chen, M.3    Castrillo, A.4    Repa, J.5    Wilpitz, D.6    Mangelsdorf, D.7    Tontonoz, P.8
  • 32
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis, A. J. 2000. Atherosclerosis. Nature 407:233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 33
    • 0036216339 scopus 로고    scopus 로고
    • Cerebrotendinous xanthomatosis: A rare disease with diverse manifestations
    • Moghadasian, M. H., G. Salen, J. J. Frohlich, and C. H. Scudamore. 2002. Cerebrotendinous xanthomatosis: a rare disease with diverse manifestations. Arch. Neurol. 59:527-529.
    • (2002) Arch. Neurol. , vol.59 , pp. 527-529
    • Moghadasian, M.H.1    Salen, G.2    Frohlich, J.J.3    Scudamore, C.H.4
  • 34
    • 0030051022 scopus 로고    scopus 로고
    • Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter
    • Nagy, L., M. Saydak, N. Shipley, S. Lu, J. P. Basilion, Z. H. Yan, P. Syka, R. A. Chandraratna, J. P. Stein, R. A. Heyman, and P. J. Davies. 1996. Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter. J. Biol. Chem. 271:4355-4365.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4355-4365
    • Nagy, L.1    Saydak, M.2    Shipley, N.3    Lu, S.4    Basilion, J.P.5    Yan, Z.H.6    Syka, P.7    Chandraratna, R.A.8    Stein, J.P.9    Heyman, R.A.10    Davies, P.J.11
  • 35
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy, L., P. Tontonoz, J. G. Alvarez, H. Chen, and R. M. Evans. 1998. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma, Cell 93:229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 37
    • 0032541028 scopus 로고    scopus 로고
    • Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways
    • Pikuleva, I. A., A. Babiker, M. R. Waterman, and I. Bjorkhem. 1998. Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways. J. Biol. Chem. 273:18153-18160.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18153-18160
    • Pikuleva, I.A.1    Babiker, A.2    Waterman, M.R.3    Bjorkhem, I.4
  • 38
    • 0034161266 scopus 로고    scopus 로고
    • Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1
    • Rastinejad, F., T. Wagner, Q. Zhao, and S. Khorasanizadeh. 2000. Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1. EMBO J. 19:1045-1054.
    • (2000) EMBO J. , vol.19 , pp. 1045-1054
    • Rastinejad, F.1    Wagner, T.2    Zhao, Q.3    Khorasanizadeh, S.4
  • 41
    • 0344413799 scopus 로고    scopus 로고
    • Automated solid-phase extraction and liquid chromatographic method for retinoid determination in biological samples
    • Ruhl, R., and F. J. Schweigert. 2003. Automated solid-phase extraction and liquid chromatographic method for retinoid determination in biological samples. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 798:309-316.
    • (2003) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.798 , pp. 309-316
    • Ruhl, R.1    Schweigert, F.J.2
  • 42
    • 0033612369 scopus 로고    scopus 로고
    • Nuclear orphan receptors control cholesterol catabolism
    • Russell, D. W. 1999. Nuclear orphan receptors control cholesterol catabolism. Cell 97:539-542.
    • (1999) Cell , vol.97 , pp. 539-542
    • Russell, D.W.1
  • 43
    • 0034672672 scopus 로고    scopus 로고
    • Oxysterol biosynthetic enzymes
    • Russell, D. W. 2000. Oxysterol biosynthetic enzymes. Biochim. Biophys. Acta 1529:126-135.
    • (2000) Biochim. Biophys. Acta , vol.1529 , pp. 126-135
    • Russell, D.W.1
  • 45
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz, P., L. Nagy, J. G. Alvarez, V. A. Thomazy, and R. M. Evans. 1998. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93:241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 46
    • 0026052251 scopus 로고
    • Functional characterization of a natural retinoic acid responsive element
    • Vivanco Ruiz, M. M., T. H. Bugge, P. Hirschmann, and H. G. Stunnenberg. 1991. Functional characterization of a natural retinoic acid responsive element. EMBO J. 10:3829-3838.
    • (1991) EMBO J. , vol.10 , pp. 3829-3838
    • Vivanco Ruiz, M.M.1    Bugge, T.H.2    Hirschmann, P.3    Stunnenberg, H.G.4
  • 47
    • 0031042762 scopus 로고    scopus 로고
    • Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR
    • Willy, P. J., and D. J. Mangelsdorf. 1997. Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR. Genes Dev. 11:289-298.
    • (1997) Genes Dev. , vol.11 , pp. 289-298
    • Willy, P.J.1    Mangelsdorf, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.