Bacteriocins from lactic acid bacteria: Purification, properties and use as biopreservatives

Brazilian Archives of Biology and Technology

Volumn 50, Issue 3, 2007, Pages 521-542

  Parada, José Luis ^a   Caron, Carolina Ricoy ^a   Medeiros, Adriane Bianchi P ^a   Soccol, Carlos Ricardo ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

Bacteriocins; Food preservation; Lactic acid bacteria; Purification

Indexed keywords

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 34547628199     PISSN: 15168913     EISSN: 15168913     Source Type: Journal    
DOI: 10.1590/s1516-89132007000300018     Document Type: Article

References (122)

1. Abee, T. (1995), Pore-forming bacteriocins of Gram-positive bacteria and selfprotection mechanisms of producer organisms. FEMS Microbiol. Lett., 129, 1-10.
2. Aslim, P.; Yuksekdag, Z. N.; Sarikaya, E. and Beyatli, Y. (2005), Determination of the bacteriocin-like substances produced by some lactic acid bacteria isolated from Turkish dairy products. LWT - Food Sci. Technol., 38, 691-694.
3. Barefoot, S. F. and Klaenhammer, T. R. (1984), Purification and characterization of the Lactobacillus acidophilus bacteriocin lactacin B. Antimicrob. Agents Chemother., 26, 328-334.
4. Belkum, M. J.; Hayema, B. J.; Geis, A.; Kok, J. and Venema, G. (1989), Cloning of two bacteriocin genes from a lactococcal bacteriocin plasmid. Appl. Environ. Microbiol., 55, 1187-1191.
5. Bhunia, A. K.; Johnson, M. C. and Ray, B. (1987), Direct detection of an antimicrobial peptide of Pediococcus acidilactici in sodium dodecyl sulfatepolyacrylamide gel-electrophoresis. J. Ind. Microbiol., 2, 319-322.
6. Bouttefroy, A. and Milliere, J. (2000), Nisin-curvaticin 13 combinations for avoiding the regrowth of bacteriocin resistant cells of bacteriocin resistant cells of Listeria monocytogenes ATCC 15313. Int. J. Food Microbiol., 62, 65-75.
7. Broadbent, J. R.; Chou, C.; Guillies, K. and Kondo, J. K. (1989), Nisin inhibits several gram-positive, mastitis-causing pathogens. J. Dairy Sci., 72, 3342-3345.
8. Bruno, M. E. C. and Montville, T. J. (1993), Common mechanistic action of bacteriocins from lactic-acid bacteria. Appl. Environ. Microbiol., 59, 3003-3010.
9. Buchman, G.; Banerjee, S. and Hansen, J. (1998), Structure, expression and evolution of gene encoding the precursor of nisin, a small protein antibiotic. J. Biol. Chem., 263, 16260-16266.
10. Burlanek, L. L. and Yousef, A. E. (2000), Solvent extraction of bacteriocins from liquid cultures. L. Appl. Microbiol., 31, 193-197.
11. Caplice, E. and Fitzgerald, G. F.. (1999), Food fermentation: role of microorganisms in food production and preservation. Int. J. Food Microbiol., 50, 131-149.
12. Caridi, A. (2002), Selection of Escherichia coli-inhibiting strains of Lactobacillus paracasei subsp. paracasei. J. Ind. Microbiol. Biotechnol., 29, 303-308.
13. Carr, F.J.; Hill, D. and Maida, N. (2002), The lactic acid bacteria: A literature survey. Crit. Rev. Microbiol., 28, 281-370.
14. Castellano, P.; FaríE.; Holzapfel, W. and Vignolo, G. (2001), Sensitivity variations of Listeria strains to the bacteriocins, lactocin 705, enterocin CRL35 and nisin. Biotechnol. Lett., 23, 605-608.
15. Castellano, P.; Raya, R. and Vignolo, G. (2003), Mode of action of lactocin 705, a two-component bacteriocin from Lactobacillus casei CRL705. Int. J. Food Microbiol., 85, 35-43.
16. Castellano, P. and Vignolo, G. (2006), Inhibition of Listeria innocua and Brochothrix thermosphacta in vacuum-packaged meat by addition of bacteriocinogenic Lactobacillus curvatus CRL705 and its bacteriocins. Lett. Appl. Microbiol., 43, 194-199.
17. Cheigh, C.; Kook, M.; Kim, S.; Hong, Y. and Pyun, Y. (2004), Simple one-step purification of nisin Z from unclarified culture broth of Lactococcus lactis subsp. lactis A164 using expanded bed ion exchange chromatography. Biotechnol. Lett., 26, 1341-1345.
18. Chopra, I.; Hodgson, J.; Metcalf, B. and Poste, G. (1998), The search for antimicrobial agents effective against bacteria resistant to multiple antibiotics. Antimicrob. Agents Chemoter., 41, 497-503.
19. Chumchalova, J. Stiles, J.; Josephsen, J. and Plocková, M. (2004), Characterization and purification of acidocin CH5, a bacteriocin produced by Lactobacillus acidophilus CH5. J. Appl. Microbiol., 96, 1082-1089.
20. Chung, K.; Dickson, J. and Creouse, J. (1989), Effects of nisin on growth of bacteria attached to meat. Appl. Environ. Microbiol., 55, 1329-1333.
21. Cintas, L. M.; Herranz, C.; Hernández, P. E.; Casaus, M. P. and Nes, L. F. (2001), Review: Bacteriocins of lactic acid bacteria. Food Sci. Tech. Int., 1, 281-305.
22. Contreras, B. G. L.; De Vuyst, L.; Devreese, B.; Busanyova, K.; Raymaeckers, J.; Bosman, F.; Sablon, E. and Vandamme, E. J. (1997), Isolation, purification, and amino acid sequence of lactobin A, one of the two bacteriocins produced by Lactobacillus amylovorus LMG P-13139. Appl. Environ. Microbiol., 63, 13-20.
23. Coughlin, R. T. and Crabb, J. H. (2002), Method of purifying lantibiotics. United States Patent 6794181.
24. Coventry, M. J.; Gordon, J. B.; Alexander, M.; Hickey, M. W. and Wan, J. (1996), A food-grade process for isolation and partial purification of bacteriocins of lactic acid bacteria that uses diatomite calcium silicate. Appl. Environ. Microbiol., 62, 1764-1769.
25. Cuozzo, S. A.; Castellano, P.; Sesma, F. J. M.; Vignolo, G. M. and Raya, R. R. (2001), Differential roles of the two-component peptides of lactocin 705 in antimicrobial activity. Current Microbiol., 46, 180-183.
26. Cuozzo, S. A.; Sesma, F.; Palacios, J. M.; De Ruiz Holgado, A. P. and Raya, R. R. (2000), Identification and nucleotide sequence of genes involved in the synthesis of lactocin 705, a two-peptide bacteriocin from Lactobacillus casei CRL 705. FEMS Microbiol. Lett., 185, 157-161.
27. Daba, H.; Pandian, S.; Gosselin, J. F.; Simard, R. E.; Huang, J. and Lacroix, C. (1991), Detection and activity of bacteriocin produced by Leuconostoc mesenteroides. Appl. Environ. Microbiol., 57, 3450-3455.
28. Deegan, L. H.; Cotter, P. D.; Hill, C. and Ross, P. (2006), Bacteriocins: Biological tools for biopreservation and shelf-life extension. Int. Dairy J., 16, 1058-1071.
29. Dellaglio, F. ; De Roissart, H.; Curk, M. C. and Janssens, D. (1994), Caractéristiques générales des bactéries latiques. In-Bactéries Latiques, H. De Roissart and F. M. Luquet, Lorica.
30. De Martinis, E. C. P. ; Públio, M. R. P.; Santarosa, P. R. and Freitas, F. Z. (2001), Antilisterial activity of lactic acid bacteria isolated from vacuum-packaged Brazilian meat and meat products. Braz. J. Microbiol., 32, 32-37.
31. De Martinis, E. C. P.; Alves, V. F. and Franco, B. D. G. De M. (2002), Bioconservação de alimentos. Biotecnologia, Ciência and Desenvolvimento, 29, 114-119.
32. De Martinis, E. C. P., Satarosa, P. R. and Freitas, F. Z. (2003), Preliminary characterization of bacteriocins produced by six lactic acid bacteria strains isolated from vacuum-packaged meat products. Clênc. Tecnol. Aliment., 23, 195-199, 2003.
33. De Vuyst, L. and Vandamme, E. J. (1992), Influence of the carbon source on nisin production in Lactococcus lactis subsp. Lactis batch fermentations. J. Gen. Microbiol., 138, 571-578.
34. De Vuyst L. (1994), Nisin production variability between natural Lactococcus lactis subsp. lactis strains. Biotechnol. Lett., 16, 287-292.
35. De Vuyst, L. (1995), Nutritional factors affecting nisin production by Lactococcus lactis subsp. lactis NIZO 22186 in a synthetic medium. J. Appl. Bacteriol., 78, 28-33.
36. Deraz, S. F.; Karlsson, E. N.; Hedstrom, M.; Andersson, M. M. and Mattiasson, B. (2005), Purification and characterisation of acidocin D20079, a bacteriocin produced by Lactobacillus acidophilus DSM 20079.7. Biotechnol., 117, 343-354.
37. Eijsink, V. G. H.; Skeie, M.; Middelhoven, P. H.; Brurberg, M. B. and Nes, I. F. (1998), Comparative studies of class IIa bacteriocins of lactic acid bacteria. Appl. Environ. Microbiol., 64, 3275-3281.
38. Engelke, G.; Gutowski-Eckel, Z; Hammelman, M, and Entian, K. D. (1992), Biosynthesis of the lantibiotic nisin: genomic organization and membrane localization of the nisb protein. Appl. Environ. Microbiol., 58, 3730-3743.
39. Engelke, G.; Gutowskieckel, Z.; Kiesau, P.; Siegers, K.; Hammelman, M. and Eltian, K. D. (1994), Regulation of nisin byosinthesis and immunity in Lactococcus lactis 6F3. Appl. Environ. Microbiol., 60, 814-825.
40. Ennahar, S.; Sashihara, T.; Sonomoto, K. and Ishizaki, A. (2000), Class Iia bacteriocins: biosynthesis, structure and activity. FEMS Microbiol. Rev., 24, 85-106.
41. Fisher, J. F.; Meroueh, S. O. and Mobashery, S. (2005), Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity. Chem. Rev., 105, 395-424.
42. Fuller, R. (1989), Probiotics in man and animals. J. Appl. Bacteriol., 66, 365-378.
43. Galvin, M.; Hill, C. and Ross, R. P. (1999), Lacticin 3147 displays activity in buffer against Gram-positive pathogens which appear insensitive in standard plate assays. Lett. Appl. Microbiol., 28, 355-358.
44. Garrity, G. M. (1984), Bergey's manual of sistematic bacteriology, vol. 2: the proteobacteria, Williams and Wilkins, New York.
45. Geisen, R.; Becker, B. and Holzapfel, W. H. (1993), Bacteriocin production of Leuconostoc carnosum LA54A at different combinations of pH and temperature. J. ind. Microbiol., 12, 337-340.
46. González-Martínez, B. E.; Gómez-Treviño, M. and Jiménez-Salas, Z. (2003), Bacteriocinas de probióticos. Rev. Salud Pública y Nutrición, 4.
47. Gross, E. and Morell, J. L. (1971), Structure of nisin. J. Am. Chem. Soc., 93, 4634-4635.
48. Guder, A.; Wiedemann, I. and Sahl, H. G. (2000), Posttranslationally modified bacteriocins: the lantibiotics. Biopoolymers, 55, 62-73.
49. Guinane, C.M.; Cotter, P. D.; Hill, C. and Ross, R. P. (2005), Microbial solutions to microbial problems; lactococcal bacteriocins for the control of undesirable biota in food. J. Appl. Microbiol., 8, 1316-1323.
50. Guinane, C. M.; Cotter, P. D.; Hill, C. and Ross, R. P. (2006), Spontaneous resistance in Lactococcus lactis IL1403 to the lantibiotic lacticin 3147. FEMS Microbiol. Lett., 260, 77-83.
51. Guyonnet, D.; Fremaux, C.; Cenatiempo, Y. and Berjeaud, J. M. (2000), Method for rapid purification of class IIa bacteriocins and comparison of their activities. Appl. Environ. Microbiol., 66, 1744-1748.
52. Haller, D.; Colbus, H.; Gänzle, M. G.; Scherenbacher, P.; Bode, C. and Hammes, W. P. (2001), Metabolic and functional properties of lactic acid bacteria in the gastro-intestinal ecosystem: a comparative in vitro study between bacteria of intestinal and fermented food origin. System. Appl. Microbiol., 24, 218-226.
53. Hastings, J. W.; Sailer, M.; Johnson, K.; Roy, K. L.; Vederas, J. C. and Stiles, M. E. (1991), Characterization of leucocin A-UAL 187 and cloning of the bacteriocin gene from Leuconostoc gelidum. J. Bacteriol., 173, 7491-7500.
54. Hernández, D.; Cardell, E. and Zárate, V. (2005), Antimicrobial activity of lactic acid bacteria isolated from Tenerife cheese: initial characterization of plantaricin TF711, a bacteriocin-like substance produced by Lactobacillus plantarum TF711. J. Appl. Microbiol., 99, 77-84.
55. Ivanova, I.; Miteva, V.; Stefanova, T. S.; Pantev, A.; Budakov, I.; Danova, S.; Moncheva, P.; Nikolova, I.; Dousset, X. and Boyaval, P. (1998), Characterization of a bacteriocin produced by Streptococcus thermophilus 81. Int. J. Food microbiol., 42, 147-158.
56. Jack, R. W.; Tagg, J. R. and Ray, B. (1995), Bacteriocins of Gram-positive bacteria. Microbiol. Rev., 59, 171-200.
57. Joerger, M. C. and Klaenhammer, T. R. (1986), Characterization and purification of helveticin J and evidence for a choromosomally determined bacteriocin produced by Lactobacillus helveticus 481. J. Bacteriol., 167, 439-446.
58. Kaletta, C. and Entian, K. D. (1989), Nisin, a peptide antibiotic: cloning and sequencing of the nis A gene and posttraductional processing of its peptide product. J. Bacteriol., 171, 1597-1601.
59. Kapil, A. (2005), The challenge of antibiotic resistance: need to contemplate. Indian J. Med. Res. 121, 83-91.
60. Kim, W. S.; Hall, R. J. and Dunn, N. W. (1997), The effect of nisin concentration and nutrient depletion on nisin production of Lactococcus lactis. Appl. Microbiol. Biotechnol., 48, 449-453.
61. Kim, W. S.; Hall, R. J. and Dunn, N. W. (1998), Improving nisin production by increasing nisin immunity/resistance genes in the producer organism Lactococcus lactis. Appl. Microbiol Biotechnol., 50, 429-433.
62. Klaenhammer, T. R.; Fremaux, C. and Hechard, Y. (1994), activité antimicrobienne des bactéries lactiques. In-Bactéries Latiques, H. De Roissart and F. M. Luquet, Lorica.
63. Koponen, O. (2004), Studies of producer self-protection and nisin biosynthesis of Lactococcus lactis. PhD Thesis, University of Helsinki, Helsinki, Finland.
64. Kuipers, O. P.; Beerthuyzen, M. M.; Siezen, R. J. and Devos, W. M. (1993), Characterization of the nisin gene-cluster nisABTCIPR of Lactococcus lactis-requirement of expression of the nisA and nisI genes for development of immunity. Eur. J. Biochem., 216, 281-291.
65. Kumar, A. and Schweiser, H. P. (2005), Bacterial resistance to antibiotics: active efflux and reduced uptake. Adv. Drug Deliv. Rev., 57, 1486-1513.
66. Lade, H. S.; Chitanand, M. P.; Gyananath, G. and Kadam, T. A. (2006), Studies on some properties of bacteriocins produced by Lactobacillus species isolated from agro-based waste. The Internet J. Microbiol., 2(1).
67. Lipsitch, M.; Bergstrom, C. T. and Levin, B. R. (2000), The epidemiology of antibiotic resistance in hospitals: paradoxes and prescriptions. Proc. Natl. Acad. Sci. USA, 97, 1938-1943.
68. Liserre, A. M.; Landgraf, M.; Destro, M. T. and Franco, B. D. G. M. (2002), Inhibition of Listeria monocytogenes by a bacteriocinogenic Lactobacillus sake strain in modified atmosphere-packaged Brazilian sausage. Meat Sci., 61, 449-455.
69. Lv, W.; Zhang, X. and Cong, W. (2005), Modelling the production of nisin by Lactococcus lactis in fed-batch culture. Appl. Microbiol. Biotechnol., 68, 322-326.
70. Mackay, V. C.; Arenose, G. and Hastings, J. W. (1997), Purification of bacteriocins of lactic acid bacteria: problems and pointers. J. Food Microbiol., 34, 1-16.
71. Martinez, R. C. R. and De Martinis, E. C. P. (2005), Antilisterial activity of a crude preparation of Lactobacillus sakei 1 bacteriocin and its lack of influence on Listeria monocytogenes haemolytic activity. Food Control, 16, 429-433.
72. Martinez, R. C. R. and De Martinis, E. C. P. (2005), Evaluation of bacteriocin-producing Lactobacillus sakei 1 against Listeria monocytogenes 1/2a growth and haemolytic activity. Braz. J. Microbiol., 36, 83-87.
73. Martinez, R. C. R. and De Martinis, E. C. P. (2006), Effect of Leuconosoc mesenteroides 11 bacteriocin in the multiplication control of Listeria monocytogenes. Ciênc. Tecnol. Aliment., 26, 52-55.
74. McAuliffe, O.; Ryan, M. P.; Ross, R. P.; Hill, C.; Breeuwer, P. and Abee, T. (1998), Lacticin 3147, a broad-spectrum bacteriocin which selectively dissipates the membrane potential. Appl. Environ. Microbiol., 64, 439-445.
75. Messi, P.; Bondi, M; Sabia, C.; Battini, R. and Manicardi, G. (2001), Detection and preliminary characterization of a bacteriocin (plantaricin 35d) produced by a Lactobacillus plantarum strain. Int. J. Food Microbiol., 64, 193-8.
76. Minahk, C. J.; Farias, M. E.; Sesma, F. and Morero, R. D. (2000), Effect of enterocin CRL35 on Listeria monocytogenes cell membrane. FEMS Microbiol. Lett., 192, 79-83.
77. Moreno, I.; Lerayer, A. S. L. and Leitão, M. F. F. (1999), Detection and characterization of bacteriocin-producing Lactococcus lactis strains. Rev. Microbiol. 30, 130-136.
78. Moreno, I.; Lerayer, A S. L.; Baldini, V. L. S. and Leitão, M. F. de F. (2000), Characterization of bacteriocins produced by Lactococcus lactis strains. Braz. J. Microbiol., 31, 184-192.
79. Morisset, D.; Berjeaud, J. M.; Marion, D.; Lacombe, C. and Frère, J. (2004), Mutational analysis of mesentericin Y105, an anti-Listeria bacteriocin, for determination of impact on bactericidal activity, in vitro secondary structure, and membrane interaction. Appl Environ. Microbiol., 70, 4672-4680.
80. Muriana, P. M. and Klaenhammer, T.R. (1991), Purification and partial characterization of lactacin F, a bacteriocin produced by Lactobacillus acidophilus 11088. Appl Environ. Microbiol., 57, 114-121.
81. Mørtvedt, C. I.; Nissen-Meyer, J.; Sletten, K. and Nes, I. F. (1991), Purification and amino acid sequence of lactocin S, a bacteriocin produced by Lactobacillus sake L45. Appl Environ. Microbiol., 57, 1829-1834.
82. Ohmomo, S.; Murata, S.; Katayaman, N.; Nitisinprasart, S.; Kobayashi, M.; Nakajima, T.; Yajima, M. and Nakanishi, K. (2000), Purification and some characteristics of enterocin ON-157, a bacteriocin produced by Enterococcus faecium NIAI 157. J. Appl. Microbiol., 88, 81-89.
83. Osmanagaoglu, Ö.; Gündüz, U.; Beyatli, Y. and Çökmüs, C. (1998), Purification and characterization of pediocin F, a bacteriocin produced by Pediococcus acidilactici F. Tr. J. Biol., 22, 217-228.
84. Pancheniak, E. de F. R. (2005), Isolamento, seleção, caracterização bioquímica e molecular, otimizaç ão de bioprocesso para produção e avaliação do potencial probiótico de Lactobacillus reuten LPB no desempenho de leitões desmamados. PhD Thesis, Universidade Federal do Paraná, Curitiba, Brazil.
85. Pancheniak, E. de F. R.; Parada, J. L. and Soccol, C. R. (2006), Inibição de Escherichia coli hemolítica suina por Lactobacillus reuteri, produtor de reuterina. Paper presented at XX Congresso Brasileiro de Ciência e Tecnologia de Alimentos, 8-11 Oct, Curitiba, Paraná.
86. Parada, J. L.; Gaón, D. and Chekherdemian, M. (1980), Enfoque bioquímico y genético de la resistencia a los antibióticos. Ars Curandi, 4, 240-245.
87. Parada, J. L. (1984), Bacterias Lácticas y el mejoramiento de microorganismos de uso industrial. La Alimentación Latinoamericana, 146, 93-102.
88. Parada J. L. (1985), Genética microbiana para o melhoramento de bacterias lácticas utilizadas na industria láctea. In-Genética de Microorganismos en Biotecnología e Engenharia Genética. Ed. J. L. Acevedo. FEALQ. Brasil.
89. Parada, J. L. (2000), Probióticos y Prebióticos. Reseña Farm Bioquim,. 3, 3-7.
90. Parada, J. L.; Sambucetti, M. E.; Zuleta, A. and Rio, M. E. (2003), Lactic acid fermented products as vehicles for probiotics. In-New Horizons in Biotechnology. Kluwer Academc Publishers, Boston, Londres, pp. 335-351.
91. Piva, A. and Headon, D. R. (1994), Pediocin A, a bacteriocin produced by Pediococcus pentosaceus FBB61. Microbiol., 140, 697-702.
92. Quiao, M.; Omaetxebarria, M. J.; Ra, R.; Oruetxebarria, I. and Saris, P. E. J. (1997), Isolation of a Lactococcus lactis strain with high resistance to nisin and increased nisin production. Biotech. Lett., 19, 199-202.
93. Rao, G. G. (1998), Risk factors for the spread of antibiotic-resistant bacteria. Aids Int., 55, 323-330.
94. Rasch, M. and Knochel, S. (1998), Variations in tolerance of Listeria monocytogenes to nisin, pediocin PA-! and bavaricin A. Lett. Appl. Microbiol., 27, 275-278.
95. Rekhif, N.; Atrih, A. and Lefebvre, G. (1994), Selection and properties of spontaneous mutants of Listeria monocytogenes ATCC 15313 resistant to different bacteriocins produced by lactic acid bacteria strains. Current Microbiol., 28, 237-241.
96. Rodríguez, E.; Arqués, J. L.; Rodríguez, R.; Nuñez, M. and Medina, M. (2003), Reuterin production by lactobacilli isolated from pig faeces and evaluation of probiotic traits. Lett. Appl. Microbiol., 37, 259-263.
97. Rodriguez, J. M. (1996), Review: Antimicrobial spectrum, structure, properties and mode of action of nisin, a bacteriocin produced by Lactococcus lactis. Food Sci. Technol. Int., 2, 61-68.
98. Ross, P. R.; Galvin, M.; McAuliffe, O.; Morgan, S. M.; Ryan, M. P.; Twomey, D. P.; Meaney, W. J. and Hill, C. (1999), Developing applications for lactococcal bacteriocins. Antonie van Leeuwenhoek, 76, 337-346.
99. Roy, P. H. (1997), Dissemination of antibiotic resistance. Med. Sci., 13, 927-933.
100. Ryan, M. P.; Meaney, W. J.; Ross, R. P. and Hill, C. (1998), Evaluation of lacticin 3147 and a teat seal containing this bacteriocin for inhibition of mastitis pathogens. Appl. Environ. Microbiol., 64, 2287-2290.
101. Saavedra, L.; Minahk, C.; Holgado, A. P. De R. and Sesma, F. (2004), Enhancement of the enterocin CRL35 activity by a synthetic peptide derived from the NH2-terminal sequence. Antimicrob. Agents Chemother., 48, 2778-2781.
102. Sahl, H. G. and Bierbaum, G. (1998), LANTIBIOTICS: Biosynthesis and biological activities of uniquely modified peptides from Gram-positive bacteria. Annu. Rev. Microbiol., 52, 41-79.
103. Schöbitz, R.; Zaror, T.; León, O. and Costa, M. (1999), A bacteriocin from Carnobacterium piscicola for the control of Listeria monocytogenes in vacuum-packaged meat. Food Microbiol., 16, 249-255.
104. Schöbitz, R.; Suazo, V.; Costa, M. and Ciampi, L. (2003), Effects of a bacteriocin-like inhibitory substance from Carnobacterium piscicola against human and salmon isolates of Listeria monocytogenes. Int. J. Food Microbiol., 84, 237-244.
105. Schöbitz, R. P.; Bórquez, P. A.; Costa, M. E.; Ciampi, L. R. and Brito, C. S. (2006), Bacteriocin like substance production by Carnobacterium piscicola in a continuous system with three culture brooms, study of antagonism against Listeria monocytogees in vacuum packaged salmon. Braz. J. Microbiol., 37, 52-57.
106. Schillinger, U.; Becker, B.; Vignolo, G. and Holzapfel, W. H. (2001), Efficacy of nisin in combination with protective cultures against Listeria monocytogenes Scott A in tofu. Int. J. Food Microbiol., 71, 159-168.
107. Sobrino, O. J.; Rodriguez, J. M.; Moreira, W. L.; Cintas, L. M.; Fernandez, M. F.; Sanz, B. and Hernandez, P. E. (1992), Sakacin M, a bacteriocin-like substance from Lactobacillus sake 148. Int. J. Food Microiol., 16, 215-25.
108. Stevens, K. A.; Sheldon, B. W.; Klapes, N. A. and Klaenhammer, T. R. (1991), Nisin treatment for inactivation of Salmonella species and other Gram-negative bacteria. Appl. Environ. Microbiol., 57, 3613-3615.
109. Suarez, A. M.; Azcona, J. I.; Rodríguez, J. M.; Sanz, B. and Hernández P. E. (1997), One-step purification of nisin A by immunoaffinity chromatography. Appl. Environ. Microbiol., 63, 4990-4992.
110. Toro, C. R. (2005), Uso de bactérias láticas probióticas na alimentação de camarões Litopenaeus vannamei como inibidoras de microrganismos patogênicos e estimulantes do sistema imune. PhD Theses, Universidade Federal do Paraná, Curitiba, Brazil.
111. Torodov, S. D. and Dicks, L. M. T. (2004), Effect of medium components on bacteriocin production by Lactobacillus pentosus ST151BR, a strain isolated from beer produced by the fermentation of maize, barley and soy flour. World J. Micobiol. Biotechnol., 20, 643-650.
112. Torodov, S. D. and Dicks, L. M. T. (2005), Lactobacillus plantarum isolated from molasses produces bacteriocins active against Gram-negative bacteria. Enzyme and Microbiol. Technol., 36, 318-326.
113. Vandermeer, J. R.; Polman, J.; Beerthuyzen, M. M.; Siezen, R. J.; Kuipers, O. P. and Devos, W. M. (1993), Characterization of the Lactococcus-lactis nisin-a operon genes nisP, encoding a subtilisin-like serine protease involved in precursor processing, and nisR, encoding a regulatory protein involved in nisin biosynthesis. J. Bacteriol., 175, 2578-2588.
114. Vaughan, E. E.; Daly, C. and Fitzgerald, G. F. (1992), Identification and characterization of helveticin V-1829, a bacteriocin produced by Lactobacillus helveticus 1829. J. Appl. Bacteriol., 73, 299-308.
115. Venema, K.; Chikindas, M. L.; Seegers, J. F. M. I.; Haandrikman, A. J.; Leenhouts, K. J.; Venema, G. and Kok, J. (1997), Rapid and efficient purification method for small, hydrophobic, cationic Bacteriocins: purification of lactococcin B and pediocin PA-1. Appl. Environ. Microbiol., 63, 305-309.
116. Vignolo, G.; Fadda, S.; De Kairuz, M. N.; De Ruiz Holgado, A. A. and Oliver, G. (1996), Control of Listeria monocytogenes in ground beef by lactocin 705, a bacteriocin produced by Lactobacillus casei CRL 705. Food Microbiol., 29, 397-402.
117. Vignolo, G.; Fadda, S.; Dekairuz, M. N.; Holgado, A. P. D. and Oliver, G. (1998), Effects of curing additives on the control of Listeria monocytogenes by lactocin 705 in meat slurry. Food Microbiol., 15, 259-264.
118. Vignolo, G.; Palacios, J.; Farías, M. E.; Sesma, F.; Schillinger, U.; Holzapfel, W. and Olliver, G. (2000), Combined effect of bacteriocins on the survival of various Listeria species in broth and meat system. Current Microbiol., 41, 410-416.
119. Xiraphi, N.; Georgalaki, M.; Van-Driessche, G.; Devreese, B.; Van-Beeumen, J.; Tsakalidou, E.; Metaxopoulos, J. and Drosinos, E. H. (2006), Purification and characterization of curvaticin L442, a bacteriocin produced by Lactobacillus curvatus L442. Antonie Van Leeuwenhoek, 89, 19-26.
120. Yang, R.; Johnson, M. C. and Ray, B. (1992), Novel method to extract large amounts of bacteriocins from lactic acid bacteria. Appl. Environ. Microbiol., 58, 3355-3359.
121. Yang, R. and Ray, B. (1994), Factors influencing production of bacteriocins by lactic acid bacteria. Food Microbiol., 11, 281-291.
122. Yoneyama, H. and Katsumata, R. (2006), Antibiotic Resistance in Bacteria and Its Future for Novel Antibiotic Development. Biosci. Biotechnol. Biochem., 70, 1060-1075.