Replacement of the muscle-specific sarcoplasmic reticulum Ca2+-ATPase isoform SERCA2a by the nonmuscle SERCA2b homologue causes mild concentric hypertrophy and impairs contraction-relaxation of the heart

Circulation Research

Volumn 89, Issue 9, 2001, Pages 838-846

  Ver Heyen, Mark ^a   Heymans, Stephane ^a   Antoons, Gudrun ^a   Reed, Thomas ^a   Periasamy, Muthu ^a   Awede, Bonaventure ^a   Lebacq, Jean ^a   Vangheluwe, Peter ^a   Dewerchin, Mieke ^a   Collen, Desiré ^a   Sipido, Karin ^a   Carmeliet, Peter ^a   Wuytack, Frank ^a  

^a Campus Gathuisberg   (Belgium)

Author keywords

Alternative splicing; Ca2+ transporting ATPase; Cardiomegaly; Cardiovascular abnormalities; Gene targeting

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM);

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CARDIOMEGALY; EXCITATION CONTRACTION COUPLING; GENE TARGETING; HEART HYPERTROPHY; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE WALL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; SARCOPLASMIC RETICULUM; TISSUE SPECIFICITY;

EID: 0035955750     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh2101.098466     Document Type: Article

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