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Volumn 23, Issue 20, 2004, Pages 4116-4125

Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells

Author keywords

Cell cycle; Proliferation; Self renewal; Stem cells; Zinc finger transcription factor

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GFI1; UNCLASSIFIED DRUG;

EID: 8144220648     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600419     Document Type: Article
Times cited : (251)

References (50)
  • 2
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K, Traver D, Miyamoto T, Weissman IL (2000) A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404: 193-197
    • (2000) Nature , vol.404 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 3
    • 0035227358 scopus 로고    scopus 로고
    • Analysis of hematopoietic phenotypes in knockout mouse models
    • Bertoncello I, Williams B (2001) Analysis of hematopoietic phenotypes in knockout mouse models. Methods Mol Biol 158: 181-203
    • (2001) Methods Mol Biol , vol.158 , pp. 181-203
    • Bertoncello, I.1    Williams, B.2
  • 5
    • 0030914867 scopus 로고    scopus 로고
    • Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment
    • Bradford GB, Williams B, Rossi R, Bertoncello I (1997) Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment. Exp Hematol 25: 445-453
    • (1997) Exp Hematol , vol.25 , pp. 445-453
    • Bradford, G.B.1    Williams, B.2    Rossi, R.3    Bertoncello, I.4
  • 6
    • 0030846533 scopus 로고    scopus 로고
    • Stem cell factor and hematopoiesis
    • Broudy VC (1997) Stem cell factor and hematopoiesis. Blood 90: 1345-1364
    • (1997) Blood , vol.90 , pp. 1345-1364
    • Broudy, V.C.1
  • 8
    • 0032980506 scopus 로고    scopus 로고
    • In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
    • Cheshier SH, Morrison SJ, Liao X, Weissman IL (1999) In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci USA 96: 3120-3125
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3120-3125
    • Cheshier, S.H.1    Morrison, S.J.2    Liao, X.3    Weissman, I.L.4
  • 9
    • 0035807964 scopus 로고    scopus 로고
    • Flk-2 is a marker in hematopoietic stem cell differentiation, a simple method to isolate long-term stem cells
    • Christensen JL, Weissman IL (2001) Flk-2 is a marker in hematopoietic stem cell differentiation, a simple method to isolate long-term stem cells. Proc Nad Acad Sci USA 98: 14541-14546
    • (2001) Proc Nad Acad Sci USA , vol.98 , pp. 14541-14546
    • Christensen, J.L.1    Weissman, I.L.2
  • 10
    • 0037687417 scopus 로고    scopus 로고
    • Targets of the transcriptional repressor oncoprotein Gf11
    • Duan Z, Horwitz M (2003) Targets of the transcriptional repressor oncoprotein Gf11. Proc Natl Acad Sci USA 100: 5932-5937
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5932-5937
    • Duan, Z.1    Horwitz, M.2
  • 12
    • 0027462484 scopus 로고
    • Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein
    • Gilks CB, Bear SE, Grimes HL, Tsichlis PN (1993) Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein. Mol Cell Biol 13: 1759-1768
    • (1993) Mol Cell Biol , vol.13 , pp. 1759-1768
    • Gilks, C.B.1    Bear, S.E.2    Grimes, H.L.3    Tsichlis, P.N.4
  • 14
    • 0029806268 scopus 로고    scopus 로고
    • The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal
    • Grimes HL, Chan TO, Zweidler-McKay PA, Tong B, Tsichlis PN (1996) The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal. Mol Cell Biol 16: 6263-6272
    • (1996) Mol Cell Biol , vol.16 , pp. 6263-6272
    • Grimes, H.L.1    Chan, T.O.2    Zweidler-McKay, P.A.3    Tong, B.4    Tsichlis, P.N.5
  • 15
    • 0035228050 scopus 로고    scopus 로고
    • Distinct classes of human stem cells that differ in proliferative and self-renewal potential
    • Guenechea G, Can OI, Dorrell C, Dick JE (2001) Distinct classes of human stem cells that differ in proliferative and self-renewal potential. Nat Immunol 2: 75-82
    • (2001) Nat Immunol , vol.2 , pp. 75-82
    • Guenechea, G.1    Can, O.I.2    Dorrell, C.3    Dick, J.E.4
  • 16
  • 17
    • 0034613734 scopus 로고    scopus 로고
    • The Notch ligand Jagged-1 represents a novel growth factor of human hematopoietic stem cells
    • Karanu FN, Murdoch B, Gallacher L, Wu DM, Koremoto M, Sakano S, Bhatia M (2000) The Notch ligand Jagged-1 represents a novel growth factor of human hematopoietic stem cells. J Exp Med 192: 1365-1372
    • (2000) J Exp Med , vol.192 , pp. 1365-1372
    • Karanu, F.N.1    Murdoch, B.2    Gallacher, L.3    Wu, D.M.4    Koremoto, M.5    Sakano, S.6    Bhatia, M.7
  • 18
    • 85047697279 scopus 로고    scopus 로고
    • High levels of the onco-protein Gfi-1 accelerate T-cell proliferation and inhibit activation induced T-cell death in Jurkat T-cells
    • Karsunky H, Mende I, Schmidt T, Möröy T (2002a) High levels of the onco-protein Gfi-1 accelerate T-cell proliferation and inhibit activation induced T-cell death in Jurkat T-cells. Oncogene 21: 1571-1579
    • (2002) Oncogene , vol.21 , pp. 1571-1579
    • Karsunky, H.1    Mende, I.2    Schmidt, T.3    Möröy, T.4
  • 20
    • 0032477741 scopus 로고    scopus 로고
    • Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin
    • Kimura S, Roberts AW, Metcalf D, Alexander WS (1998) Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin. Proc Natl Acad Sci USA 95: 1195-1200
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1195-1200
    • Kimura, S.1    Roberts, A.W.2    Metcalf, D.3    Alexander, W.S.4
  • 21
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo M, Weissman IL, Akashi K (1997) Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91: 661-672
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 23
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G (2003) Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423: 255-260
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 24
    • 0032528354 scopus 로고    scopus 로고
    • Lineage commitment and maturation in hematopoietic cells. The case for extrinsic regulation
    • Metcalf D (1998) Lineage commitment and maturation in hematopoietic cells. The case for extrinsic regulation. Blood 92: 345-352
    • (1998) Blood , vol.92 , pp. 345-352
    • Metcalf, D.1
  • 25
    • 0028534860 scopus 로고
    • The long-term repopulating subsets of hematopoietic stem cells is deterministic and isolatable by phenotype
    • Morrison SJ, Weissman IL (1994) The long-term repopulating subsets of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1: 661-673
    • (1994) Immunity , vol.1 , pp. 661-673
    • Morrison, S.J.1    Weissman, I.L.2
  • 26
    • 0036081059 scopus 로고    scopus 로고
    • Myeloid erythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of Day 8 CFU-S
    • Nakorn TN, Miyamoto T, Weissman IL (2002) Myeloid erythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of Day 8 CFU-S. J Clin Invest 109: 1579-1585
    • (2002) J Clin Invest , vol.109 , pp. 1579-1585
    • Nakorn, T.N.1    Miyamoto, T.2    Weissman, I.L.3
  • 28
    • 0037130481 scopus 로고    scopus 로고
    • Overexpression of a dominant negative form of STAT3 selectively impairs hematopoietic stem cell activity
    • Oh IH, Eaves CJ (2002) Overexpression of a dominant negative form of STAT3 selectively impairs hematopoietic stem cell activity. Oncogene 21: 4778-4787
    • (2002) Oncogene , vol.21 , pp. 4778-4787
    • Oh, I.H.1    Eaves, C.J.2
  • 31
    • 0030051967 scopus 로고    scopus 로고
    • Ex vivo expansion of murine marrow cells with interleukin-3: Interleukin-6: Interleukin-11: And stem cell factor leads to impaired engraftment in irradiated hosts
    • Peters SO, Kittler ELW, Ramshaw HS, Quesenberry PJ (1996) Ex vivo expansion of murine marrow cells with interleukin-3: interleukin-6: interleukin-11: and stem cell factor leads to impaired engraftment in irradiated hosts. Blood 87: 30-37
    • (1996) Blood , vol.87 , pp. 30-37
    • Peters, S.O.1    Kittler, E.L.W.2    Ramshaw, H.S.3    Quesenberry, P.J.4
  • 34
    • 0031060318 scopus 로고    scopus 로고
    • Characterization of pal-1: A common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice
    • Scheijen B, Jonkers J, Acton D, Berns A (1997) Characterization of pal-1: a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice. J Virol 71: 9-16
    • (1997) J Virol , vol.71 , pp. 9-16
    • Scheijen, B.1    Jonkers, J.2    Acton, D.3    Berns, A.4
  • 35
    • 0032547947 scopus 로고    scopus 로고
    • Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis
    • Schmidt T, Karsunky H, Gau E, Zevnik B, Elsässer HP, Möröy T (1998a) Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis. Oncogene 17: 2661-2667
    • (1998) Oncogene , vol.17 , pp. 2661-2667
    • Schmidt, T.1    Karsunky, H.2    Gau, E.3    Zevnik, B.4    Elsässer, H.P.5    Möröy, T.6
  • 36
    • 0032531041 scopus 로고    scopus 로고
    • Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection
    • Schmidt T, Karsunky H, Rödel B, Zevnik B, Elsässer HP, Möröy T (1998b) Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection. EMBO J 17: 5349-5359
    • (1998) EMBO J , vol.17 , pp. 5349-5359
    • Schmidt, T.1    Karsunky, H.2    Rödel, B.3    Zevnik, B.4    Elsässer, H.P.5    Möröy, T.6
  • 37
    • 0029883328 scopus 로고    scopus 로고
    • MoMuLV proviral integrations identified by Sup-F selection in tumors from infected myc/pim bitransgenic mice correlate with activation of the gfi-1 gene
    • Schmidt T, Zörnig M, Beneke R, Möröy T (1996) MoMuLV proviral integrations identified by Sup-F selection in tumors from infected myc/pim bitransgenic mice correlate with activation of the gfi-1 gene. Nucleic Acids Res 24: 2528-2534
    • (1996) Nucleic Acids Res , vol.24 , pp. 2528-2534
    • Schmidt, T.1    Zörnig, M.2    Beneke, R.3    Möröy, T.4
  • 38
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude GJ, Heimfeld S, Weissman IL (1988) Purification and characterization of mouse hematopoietic stem cells. Science 241: 58-62
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 39
    • 0036529989 scopus 로고    scopus 로고
    • Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome
    • Stier S, Cheng T, Dombkowski D, Carlesso N, Scadden DT (2002) Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood 99: 2369-2378
    • (2002) Blood , vol.99 , pp. 2369-2378
    • Stier, S.1    Cheng, T.2    Dombkowski, D.3    Carlesso, N.4    Scadden, D.T.5
  • 42
    • 0037232661 scopus 로고    scopus 로고
    • The zinc finger transcription factor Gfi1: Implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival
    • Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ (2003) The zinc finger transcription factor Gfi1: implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development 130: 221-232
    • (2003) Development , vol.130 , pp. 221-232
    • Wallis, D.1    Hamblen, M.2    Zhou, Y.3    Venken, K.J.4    Schumacher, A.5    Grimes, H.L.6    Zoghbi, H.Y.7    Orkin, S.H.8    Bellen, H.J.9
  • 43
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells, unit of development, unit of regeneration, and its evolution
    • Weissman IL (2000) Stem cells, unit of development, unit of regeneration, and its evolution. Cell 100: 157-168
    • (2000) Cell , vol.100 , pp. 157-168
    • Weissman, I.L.1
  • 46
    • 4644272644 scopus 로고    scopus 로고
    • Gfi1:GFP knock-in mutant reveals differential expression and autoregulation of the gene growth factor independence 1 (Gfi1) during lymphocyte development
    • Jul 13 [Epub ahead of print]
    • Yücel R, Kosan C, Heyd F, Möröy T (2004) Gfi1:GFP knock-in mutant reveals differential expression and autoregulation of the gene growth factor independence 1 (Gfi1) during lymphocyte development. J Biol Chem, Jul 13 [Epub ahead of print]
    • (2004) J Biol Chem
    • Yücel, R.1    Kosan, C.2    Heyd, F.3    Möröy, T.4
  • 47
    • 0034332097 scopus 로고    scopus 로고
    • Murine hematopoietic stem cell characterization and its regulation in BM transplantation
    • Zhao Y, Lin Y, Zhan Y, Yang G, Louie J, Harrison DE, Anderson WF (2000) Murine hematopoietic stem cell characterization and its regulation in BM transplantation. Blood 96: 3016-3022
    • (2000) Blood , vol.96 , pp. 3016-3022
    • Zhao, Y.1    Lin, Y.2    Zhan, Y.3    Yang, G.4    Louie, J.5    Harrison, D.E.6    Anderson, W.F.7
  • 49
    • 0029991422 scopus 로고    scopus 로고
    • Zinc finger protein GFI-1 cooperates with myc and pim-1 in T-cell lymphomagenesis by reducing the requirements for IL-2
    • Zörnig M, Schmidt T, Karsunky H, Grzeschiczek A, Möröy T (1996) Zinc finger protein GFI-1 cooperates with myc and pim-1 in T-cell lymphomagenesis by reducing the requirements for IL-2. Oncogene 12: 1789-1801
    • (1996) Oncogene , vol.12 , pp. 1789-1801
    • Zörnig, M.1    Schmidt, T.2    Karsunky, H.3    Grzeschiczek, A.4    Möröy, T.5
  • 50
    • 0029897536 scopus 로고    scopus 로고
    • Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor
    • Zweidler-Mckay PA, Grimes HL, Flubacher MM, Tsichlis PN (1996) Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor. Mol Cell Biol 16: 4024-4034
    • (1996) Mol Cell Biol , vol.16 , pp. 4024-4034
    • Zweidler-Mckay, P.A.1    Grimes, H.L.2    Flubacher, M.M.3    Tsichlis, P.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.