-
1
-
-
0024327898
-
The leukocyte common antigen family
-
Thomas, M. L. 1989. The leukocyte common antigen family. Annu. Rev. Immunol. 7:339.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 339
-
-
Thomas, M.L.1
-
2
-
-
0031570545
-
Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-ζ and ZAP-70
-
Stone, J. D., L. A. Conroy, K. F. Byth, R. A. Hederer, S. Howlett, Y. Takemoto, N. Holmes, and D. R. Alexander. 1997. Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-ζ and ZAP-70. J. Immunol. 158:5773.
-
(1997)
J. Immunol.
, vol.158
, pp. 5773
-
-
Stone, J.D.1
Conroy, L.A.2
Byth, K.F.3
Hederer, R.A.4
Howlett, S.5
Takemoto, Y.6
Holmes, N.7
Alexander, D.R.8
-
3
-
-
0030023652
-
Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45
-
Cyster, J. G., J. I. Healy, K. Kishihara, T. W. Mak, M. L. Thomas, and C. C. Goodnow. 1996. Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45. Nature 381:325.
-
(1996)
Nature
, vol.381
, pp. 325
-
-
Cyster, J.G.1
Healy, J.I.2
Kishihara, K.3
Mak, T.W.4
Thomas, M.L.5
Goodnow, C.C.6
-
4
-
-
0033794973
-
The CD45 tyrosine phosphatase: A positive and negative regulator of immune cell function
-
Alexander, D. R. 2000. The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell function. Semin. Immunol. 12:349.
-
(2000)
Semin. Immunol.
, vol.12
, pp. 349
-
-
Alexander, D.R.1
-
5
-
-
0029864147
-
+ thymocytes, and in B-cell maturation
-
+ thymocytes, and in B-cell maturation. J. Exp. Med. 183:1707.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1707
-
-
Byth, K.F.1
Conroy, L.A.2
Howlett, S.3
Smith, A.J.H.4
May, J.5
Alexander, D.R.6
Holmes, N.7
-
6
-
-
0027296521
-
Normal B lymphocyte development but impaired T cell maturation in CD45-exon 6 protein tyrosine phosphatase deficient mice
-
Kishihara, K., J. Penninger, V. A. Wallace, T. M. Kundig, K. Kawai, D. Wakeham, E. Timms, K. Pfeffer, P. Ohashi, M. L. Thomas, et al. 1993. Normal B lymphocyte development but impaired T cell maturation in CD45-exon 6 protein tyrosine phosphatase deficient mice. Cell 74:143.
-
(1993)
Cell
, vol.74
, pp. 143
-
-
Kishihara, K.1
Penninger, J.2
Wallace, V.A.3
Kundig, T.M.4
Kawai, K.5
Wakeham, D.6
Timms, E.7
Pfeffer, K.8
Ohashi, P.9
Thomas, M.L.10
-
7
-
-
0033399264
-
Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice
-
Mee, P. J., M. Turner, M. A. Basson, P. S. Costello, R. Zamoyska, and V. L. J. Tybulewicz. 1999. Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase-deficient mice. Eur. J. Immunol. 29:2923.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 2923
-
-
Mee, P.J.1
Turner, M.2
Basson, M.A.3
Costello, P.S.4
Zamoyska, R.5
Tybulewicz, V.L.J.6
-
8
-
-
0031172246
-
CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion
-
Roach, T., S. Slater, M. Koval, L. White, E. D. Cahir-McFarland, M. Okumura, M. Thomas, and E. Brown. 1997. CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion. Curr. Biol. 7:408.
-
(1997)
Curr. Biol.
, vol.7
, pp. 408
-
-
Roach, T.1
Slater, S.2
Koval, M.3
White, L.4
Cahir-McFarland, E.D.5
Okumura, M.6
Thomas, M.7
Brown, E.8
-
9
-
-
0034711317
-
CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway
-
Tan, J., T. Town, and M. Mullan. 2000. CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway. J. Biol. Chem. 275:372.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 372
-
-
Tan, J.1
Town, T.2
Mullan, M.3
-
10
-
-
0035905767
-
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
-
Irie-Sasaki, J., T. Sasaki, W. Matsumoto, A. Opavsky, M. Cheng, G. Welstead, E. Griffiths, C. Krawczyk, C. D. Richardson, K. Aitken, et al. 2001. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature 409:349.
-
(2001)
Nature
, vol.409
, pp. 349
-
-
Irie-Sasaki, J.1
Sasaki, T.2
Matsumoto, W.3
Opavsky, A.4
Cheng, M.5
Welstead, G.6
Griffiths, E.7
Krawczyk, C.8
Richardson, C.D.9
Aitken, K.10
-
11
-
-
0028346560
-
CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development
-
Trowbridge, I. S., and M. L. Thomas. 1994. CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 12:85.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 85
-
-
Trowbridge, I.S.1
Thomas, M.L.2
-
12
-
-
0033151580
-
Biochemical association of CD45 with the T cell receptor complex: Regulation by CD45 isoform and during T cell activation
-
Leitenberg, D., Y. Boutin, D. D. Lu, and K. Bottomly. 1999. Biochemical association of CD45 with the T cell receptor complex: regulation by CD45 isoform and during T cell activation. Immunity. 10:701.
-
(1999)
Immunity
, vol.10
, pp. 701
-
-
Leitenberg, D.1
Boutin, Y.2
Lu, D.D.3
Bottomly, K.4
-
13
-
-
18544371851
-
lck tyrosine kinase in T cell antigen receptor signal transduction
-
lck tyrosine kinase in T cell antigen receptor signal transduction. J. Biol. Chem. 277:1912.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1912
-
-
Dornan, S.1
Sebestyen, Z.2
Gamble, J.3
Nagy, P.4
Bodnar, A.5
Alldridge, L.6
Doe, S.7
Holmes, N.8
Goff, L.K.9
Beverley, P.10
-
14
-
-
0036346992
-
Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms
-
Xu, Z., and A. Weiss. 2002. Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms. Nat. Immunol. 3:764.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 764
-
-
Xu, Z.1
Weiss, A.2
-
15
-
-
0030586604
-
Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains
-
Okumura, M., R. J. Matthews, B. Robb, G. W. Litman, P. Bork, and M. L. Thomas. 1996. Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains. J. Immunol. 157:1569.
-
(1996)
J. Immunol.
, vol.157
, pp. 1569
-
-
Okumura, M.1
Matthews, R.J.2
Robb, B.3
Litman, G.W.4
Bork, P.5
Thomas, M.L.6
-
16
-
-
0029597765
-
Characterization of lineage restricted forms of a Xenopus CD45 homologue
-
Barritt, L. C., and J. B. Turpen. 1995. Characterization of lineage restricted forms of a Xenopus CD45 homologue. Dev. Comp. Immunol. 19:525.
-
(1995)
Dev. Comp. Immunol.
, vol.19
, pp. 525
-
-
Barritt, L.C.1
Turpen, J.B.2
-
17
-
-
0035889895
-
CD45 modulates galectin-1-induced T cell death: Regulation by expression of core 2 O-glycans
-
Nguyen, J. T., D. P. Evans, M. Galvan, K. E. Pace, D. Leitenberg, T. N. Bui, and L. G. Baum. 2001. CD45 modulates galectin-1-induced T cell death: regulation by expression of core 2 O-glycans. J. Immunol. 167:5697.
-
(2001)
J. Immunol.
, vol.167
, pp. 5697
-
-
Nguyen, J.T.1
Evans, D.P.2
Galvan, M.3
Pace, K.E.4
Leitenberg, D.5
Bui, T.N.6
Baum, L.G.7
-
18
-
-
0041031355
-
Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor
-
Martínez-Pomares, L., P. R. Crocker, R. Da Silva, N. Holmes, C. Colominas, P. Rudd, R. Dwek, and S. Gordon. 1999. Cell-specific glycoforms of sialoadhesin and CD45 are counter-receptors for the cysteine-rich domain of the mannose receptor. J. Biol. Chem. 274:35211.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 35211
-
-
Martínez-Pomares, L.1
Crocker, P.R.2
Da Silva, R.3
Holmes, N.4
Colominas, C.5
Rudd, P.6
Dwek, R.7
Gordon, S.8
-
19
-
-
0029918134
-
Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22
-
Van der Merwe, P. A., P. R. Crocker, M. Vinson, A. N. Barclay, R. Schauer, and S. Kelm. 1996. Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22. J. Biol. Chem. 271:9273.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9273
-
-
Van der Merwe, P.A.1
Crocker, P.R.2
Vinson, M.3
Barclay, A.N.4
Schauer, R.5
Kelm, S.6
-
20
-
-
0030070341
-
The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation
-
Leitenberg, D., T. J. Novak, D. Farber, B. R. Smith, and K. Bottomly. 1996. The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation. J. Exp. Med. 183:249.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 249
-
-
Leitenberg, D.1
Novak, T.J.2
Farber, D.3
Smith, B.R.4
Bottomly, K.5
-
21
-
-
0029759927
-
Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization
-
Bilwes, A. M., J. den Hertog, T. Hunter, and J. P. Noel. 1996. Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization. Nature 382:555.
-
(1996)
Nature
, vol.382
, pp. 555
-
-
Bilwes, A.M.1
Den Hertog, J.2
Hunter, T.3
Noel, J.P.4
-
22
-
-
0032472226
-
Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge
-
Majeti, R., A. M. Bilwes, J. P. Noel, T. Hunter, and A. Weiss. 1998. Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge. Science 279:88.
-
(1998)
Science
, vol.279
, pp. 88
-
-
Majeti, R.1
Bilwes, A.M.2
Noel, J.P.3
Hunter, T.4
Weiss, A.5
-
23
-
-
0031962758
-
Transcriptional regulation of vav, a gene expressed throughout the hematopoietic compartment
-
Ogilvy, S., A. G. Elefanty, J. Visvader, M. L. Bath, A. W. Harris, and J. M. Adams. 1998. Transcriptional regulation of vav, a gene expressed throughout the hematopoietic compartment. Blood 91:419.
-
(1998)
Blood
, vol.91
, pp. 419
-
-
Ogilvy, S.1
Elefanty, A.G.2
Visvader, J.3
Bath, M.L.4
Harris, A.W.5
Adams, J.M.6
-
24
-
-
0033593038
-
Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival
-
Ogilvy, S., D. Metcalf, C. G. Print, M. L. Bath, A. W. Harris, and J. M. Adams. 1999. Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival. Proc. Natl. Acad. Sci. USA 96:14943.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14943
-
-
Ogilvy, S.1
Metcalf, D.2
Print, C.G.3
Bath, M.L.4
Harris, A.W.5
Adams, J.M.6
-
25
-
-
0033567901
-
Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment
-
Ogilvy, S., D. Metcalf, D. Gibson, M. L. Bath, A. W. Harris, and J. M. Adams. 1999. Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment. Blood 94:1855.
-
(1999)
Blood
, vol.94
, pp. 1855
-
-
Ogilvy, S.1
Metcalf, D.2
Gibson, D.3
Bath, M.L.4
Harris, A.W.5
Adams, J.M.6
-
26
-
-
1842340099
-
Sequences of Ly-5 cDNA: Isoform-related diversity of Ly-5 mRNA
-
Saga, Y., J. S. Tung, F. W. Shen, and E. A. Boyse. 1986. Sequences of Ly-5 cDNA: isoform-related diversity of Ly-5 mRNA. Proc. Natl. Acad. Sci. USA 83:6940.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 6940
-
-
Saga, Y.1
Tung, J.S.2
Shen, F.W.3
Boyse, E.A.4
-
28
-
-
0030963615
-
Structure and function of the pre-T cell receptor
-
von Boehmer, H., and H. J. Fehling. 1997. Structure and function of the pre-T cell receptor. Annu. Rev. Immunol. 15:432.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 432
-
-
Von Boehmer, H.1
Fehling, H.J.2
-
30
-
-
0036498795
-
Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development
-
Su, T. T., and D. J. Rawlings. 2002. Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development. J. Immunol. 168:2101.
-
(2002)
J. Immunol.
, vol.168
, pp. 2101
-
-
Su, T.T.1
Rawlings, D.J.2
-
31
-
-
0029912235
-
Locus control region function and heterochromatin-induced position effect variegation
-
Festenstein, R., M. Tolaini, P. Corbella, C. Mamalaki, J. Parrington, M. Fox, A. Miliou, M. Jones, and D. Kioussis. 1996. Locus control region function and heterochromatin-induced position effect variegation. Science 27:1123.
-
(1996)
Science
, vol.27
, pp. 1123
-
-
Festenstein, R.1
Tolaini, M.2
Corbella, P.3
Mamalaki, C.4
Parrington, J.5
Fox, M.6
Miliou, A.7
Jones, M.8
Kioussis, D.9
-
32
-
-
0031112267
-
T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45
-
Kozieradzki, I., T. Kundig, K. Kishihara, C. J. Ong, D. Chiu, V. A. Wallace, K. Kawai, E. Timms, J. Ionescu, P. Ohashi, et al. 1997. T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45. J. Immunol. 158:3.130.
-
(1997)
J. Immunol.
, vol.158
, Issue.3
, pp. 130
-
-
Kozieradzki, I.1
Kundig, T.2
Kishihara, K.3
Ong, C.J.4
Chiu, D.5
Wallace, V.A.6
Kawai, K.7
Timms, E.8
Ionescu, J.9
Ohashi, P.10
-
33
-
-
0026536583
-
Expression of variable exon A-specific, B-specific and C-specific CD45 determinants on peripheral and thymic T cell populations
-
Hatheock, K. S., G. Laszlo, H. B. Dickler, S. O. Sharrow, P. Johnson, I. S. Trowbridge, and R. J. Hodes. 1992. Expression of variable exon A-specific, B-specific and C-specific CD45 determinants on peripheral and thymic T cell populations. J. Immunol. 148:19.
-
(1992)
J. Immunol.
, vol.148
, pp. 19
-
-
Hatheock, K.S.1
Laszlo, G.2
Dickler, H.B.3
Sharrow, S.O.4
Johnson, P.5
Trowbridge, I.S.6
Hodes, R.J.7
-
34
-
-
0029561333
-
Differential requirements of CD45 for lymphocyte development and function
-
Kong, Y. Y., K. Kishihara, H. Sumichika, T. Nakamura, M. Kaneko, and K. Nomoto. 1995. Differential requirements of CD45 for lymphocyte development and function. Eur. J. Immunol. 25:3431.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 3431
-
-
Kong, Y.Y.1
Kishihara, K.2
Sumichika, H.3
Nakamura, T.4
Kaneko, M.5
Nomoto, K.6
-
35
-
-
2242446203
-
Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling
-
Petro, J. B., R. M. Gerstein, J. Lowe, R. S. Carter, N. Shinners, and W. N. Khan. 2002. Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling. J. Biol. Chem. 277:48009.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48009
-
-
Petro, J.B.1
Gerstein, R.M.2
Lowe, J.3
Carter, R.S.4
Shinners, N.5
Khan, W.N.6
-
36
-
-
0035378223
-
Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation
-
Doody, G. M., S. E. Bell, E. Vigorito, E. Clayton, S. McAdam, R. Tooze, C. Fernandez, I. J. Lee, and M. Turner. 2001. Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation. Nat. Immunol. 2:542.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 542
-
-
Doody, G.M.1
Bell, S.E.2
Vigorito, E.3
Clayton, E.4
McAdam, S.5
Tooze, R.6
Fernandez, C.7
Lee, I.J.8
Turner, M.9
-
37
-
-
0033624638
-
Phospholipase Cy2 is essential in the functions of B cell and several Fc receptors
-
Wang, D., J. Feng, R. Wen, J.-C. Marine, M. Y. Sangster, E. Parganas, A. Hoffmeyer, C. W. Jackson, J. L. Cleveland, P. J. Murray, and J. M. Ihle. 2000. Phospholipase Cy2 is essential in the functions of B cell and several Fc receptors. Immunity 13:25.
-
(2000)
Immunity
, vol.13
, pp. 25
-
-
Wang, D.1
Feng, J.2
Wen, R.3
Marine, J.-C.4
Sangster, M.Y.5
Parganas, E.6
Hoffmeyer, A.7
Jackson, C.W.8
Cleveland, J.L.9
Murray, P.J.10
Ihle, J.M.11
-
38
-
-
0033712984
-
Xid-like phenotypes: A B cell signalosome takes shape
-
Fruhman, D. A., A. B. Satterthwaite, and O. N. Witte. 2000. Xid-like phenotypes: a B cell signalosome takes shape. Immunity 13:1.
-
(2000)
Immunity
, vol.13
, pp. 1
-
-
Fruhman, D.A.1
Satterthwaite, A.B.2
Witte, O.N.3
-
39
-
-
0036232606
-
The tyrosine kinase Lyn is required for B cell development beyond the T1 stage in the spleen: Rescue by over-expression of Bcl-2
-
Meade, J., C. Fernandez, and M. Turner. 2002. The tyrosine kinase Lyn is required for B cell development beyond the T1 stage in the spleen: rescue by over-expression of Bcl-2. Eur. J. Immunol. 32:1029.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1029
-
-
Meade, J.1
Fernandez, C.2
Turner, M.3
-
40
-
-
0026706364
-
CD45 expression by B cells: Expression of different CD45 isoforms by subpopulations of activated B cells
-
Hathcock, K. S., H. Hirano, S. Murakami, and R. J. Hodes. 1992. CD45 expression by B cells: expression of different CD45 isoforms by subpopulations of activated B cells. J. Immunol. 149:2286.
-
(1992)
J. Immunol.
, vol.149
, pp. 2286
-
-
Hathcock, K.S.1
Hirano, H.2
Murakami, S.3
Hodes, R.J.4
-
41
-
-
0037307651
-
A CD45 minigene restores regulated isoform expression and immune function in CD45 deficient mice: Therapeutic implications for human CD45-null severe combined immunodeficiency
-
Virts, E. L., O. Diago, and W. C. Raschke. 2003. A CD45 minigene restores regulated isoform expression and immune function in CD45 deficient mice: therapeutic implications for human CD45-null severe combined immunodeficiency. Blood 101:849.
-
(2003)
Blood
, vol.101
, pp. 849
-
-
Virts, E.L.1
Diago, O.2
Raschke, W.C.3
|