Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy

Molecular Cell

Volumn 10, Issue 1, 2002, Pages 35-44

  Mankodi, Ami ^a   Takahashi, Masanori P ^b   Jiang, Hong ^a   Beck, Carol L ^c   Bowers, William J ^a   Moxley, Richard T ^a   Cannon, Stephen C ^b   Thornton, Charles A ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; MESSENGER RNA PRECURSOR; PROTEIN; PROTEIN CIC 1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MEMBRANE DEPOLARIZATION; MOUSE; MUSCLE ACTION POTENTIAL; MUSCLE ATROPHY; MUSCLE EXCITATION; MYOTONIA; MYOTONIC DYSTROPHY; NONHUMAN; PATHOGENESIS; RNA PROCESSING; RNA SPLICING; SKELETAL MUSCLE; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0036347525     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00563-4     Document Type: Article

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