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Volumn 162, Issue 1, 2003, Pages 149-160

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan

Author keywords

Aging; Basal lamina; CRE loxP; ECM; Integrin receptors

Indexed keywords

FIBRONECTIN; GLYCOPROTEIN;

EID: 0038825157     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200212079     Document Type: Article
Times cited : (266)

References (60)
  • 1
    • 0034712281 scopus 로고    scopus 로고
    • Regulation of CS1 fibronectin expression and function by IL-1 in endothelial cells
    • Boyle, D.L., Y. Shi, S. Gay, and G.S. Firestein. 2000. Regulation of CS1 fibronectin expression and function by IL-1 in endothelial cells. Cell. Immunol. 200:1-7.
    • (2000) Cell. Immunol. , vol.200 , pp. 1-7
    • Boyle, D.L.1    Shi, Y.2    Gay, S.3    Firestein, G.S.4
  • 2
    • 0028232359 scopus 로고
    • A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon
    • Caputi, M., G. Casari, S. Guenzi, R. Tagliabue, A. Sidoli, C.A. Melo, and F.E. Baralle. 1994. A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon. Nucleic Acids Res. 22:1018-1022.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1018-1022
    • Caputi, M.1    Casari, G.2    Guenzi, S.3    Tagliabue, R.4    Sidoli, A.5    Melo, C.A.6    Baralle, F.E.7
  • 3
    • 0029086215 scopus 로고
    • Analysis of the linkage between fibronectin alternative spliced sites during ageing in rat tissues
    • Caputi, M., F.E. Baralle, and C.A. Melo. 1995. Analysis of the linkage between fibronectin alternative spliced sites during ageing in rat tissues. Biochim. Biophys. Acta. 1263:53-59.
    • (1995) Biochim. Biophys. Acta , vol.1263 , pp. 53-59
    • Caputi, M.1    Baralle, F.E.2    Melo, C.A.3
  • 4
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 5
    • 0020264236 scopus 로고
    • Fibronectin and fibrin provide a provisional matrix for epidermal cell migration during wound reepithelialization
    • Clark, R.A., J.M. Lanigan, P. DellaPelle, E. Manseau, H.F. Dvorak, and R.B. Colvin. 1982. Fibronectin and fibrin provide a provisional matrix for epidermal cell migration during wound reepithelialization. J. Invest. Dermatol. 79:264-269.
    • (1982) J. Invest. Dermatol. , vol.79 , pp. 264-269
    • Clark, R.A.1    Lanigan, J.M.2    DellaPelle, P.3    Manseau, E.4    Dvorak, H.F.5    Colvin, R.B.6
  • 6
    • 0020584786 scopus 로고
    • Fibronectin beneath reepithelializing epidermis in vivo: Sources and significance
    • Clark, R.A., H.J. Winn, H.F. Dvorak, and R.B. Colvin. 1983. Fibronectin beneath reepithelializing epidermis in vivo: sources and significance. J. Invest. Dermatol. 80:26s-30s.
    • (1983) J. Invest. Dermatol. , vol.80
    • Clark, R.A.1    Winn, H.J.2    Dvorak, H.F.3    Colvin, R.B.4
  • 7
    • 0026564757 scopus 로고
    • Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos
    • DeSimone, D.W., P.A. Norton, and R.O. Hynes. 1992. Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos. Dev. Biol. 149:357-369.
    • (1992) Dev. Biol. , vol.149 , pp. 357-369
    • DeSimone, D.W.1    Norton, P.A.2    Hynes, R.O.3
  • 8
    • 0035064152 scopus 로고    scopus 로고
    • Lysosomal acid lipase-deficient mice: Depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span
    • Du, H., M. Heur, M. Duanmu, G.A. Grabowski, D.Y. Hui, D.P. Witte, and J. Mishra. 2001. Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span. J. Lipid Res. 42:489-500.
    • (2001) J. Lipid Res. , vol.42 , pp. 489-500
    • Du, H.1    Heur, M.2    Duanmu, M.3    Grabowski, G.A.4    Hui, D.Y.5    Witte, D.P.6    Mishra, J.7
  • 9
    • 0031010393 scopus 로고    scopus 로고
    • HRS/SRp40-mediated inclusion of the fibronectin EIIIB exon, a possible cause of increased EIIIB expression in proliferating liver
    • Du, K., Y. Peng, L.E. Greenbaum, B.A. Haber, and R. Taub. 1997. HRS/SRp40-mediated inclusion of the fibronectin EIIIB exon, a possible cause of increased EIIIB expression in proliferating liver. Mol. Cell. Biol. 17:4096-4104.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4096-4104
    • Du, K.1    Peng, Y.2    Greenbaum, L.E.3    Haber, B.A.4    Taub, R.5
  • 10
    • 0028875886 scopus 로고
    • Alternative splicing of fibronectin - Many different proteins but few different functions
    • ffrench-Constant, C. 1995. Alternative splicing of fibronectin - many different proteins but few different functions. Exp. Cell Res. 221:261-271.
    • (1995) Exp. Cell Res. , vol.221 , pp. 261-271
    • Ffrench-Constant, C.1
  • 11
    • 0024406027 scopus 로고
    • Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo
    • ffrench-Constant, C., and R.O. Hynes. 1989. Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo. Development. 106:375-388.
    • (1989) Development , vol.106 , pp. 375-388
    • Ffrench-Constant, C.1    Hynes, R.O.2
  • 12
    • 0024344620 scopus 로고
    • Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat
    • ffrench-Constant, C., L. Van de Water, H.F. Dvorak, and R.O. Hynes. 1989. Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat. J. Cell Biol. 109:903-914.
    • (1989) J. Cell Biol. , vol.109 , pp. 903-914
    • Ffrench-Constant, C.1    Van de Water, L.2    Dvorak, H.F.3    Hynes, R.O.4
  • 13
    • 0036790091 scopus 로고    scopus 로고
    • Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro
    • Fukuda, T., N. Yoshida, Y. Kataoka, R. Manabe, Y. Mizuno-Horikawa, M. Sato, K. Kuriyama, N. Yasui, and K. Sekiguchi. 2002. Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro. Cancer Res. 62:5603-5610.
    • (2002) Cancer Res. , vol.62 , pp. 5603-5610
    • Fukuda, T.1    Yoshida, N.2    Kataoka, Y.3    Manabe, R.4    Mizuno-Horikawa, Y.5    Sato, M.6    Kuriyama, K.7    Yasui, N.8    Sekiguchi, K.9
  • 14
    • 0027379724 scopus 로고
    • Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin
    • George, E.L., E.N. Georges-Labouesse, R.S. Patel-King, H. Rayburn, and R.O. Hynes. 1993. Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development. 119:1079-1091.
    • (1993) Development , vol.119 , pp. 1079-1091
    • George, E.L.1    Georges-Labouesse, E.N.2    Patel-King, R.S.3    Rayburn, H.4    Hynes, R.O.5
  • 15
    • 0029804825 scopus 로고    scopus 로고
    • Mesodermal development in mouse embryos mutant for fibronectin
    • Georges-Labouesse, E.N., E.L. George, H. Rayburn, and R.O. Hynes. 1996. Mesodermal development in mouse embryos mutant for fibronectin. Dev. Dyn. 207:145-156.
    • (1996) Dev. Dyn. , vol.207 , pp. 145-156
    • Georges-Labouesse, E.N.1    George, E.L.2    Rayburn, H.3    Hynes, R.O.4
  • 16
    • 0032487578 scopus 로고    scopus 로고
    • Cre-loxP-mediated inactivation of the α6A integrin splice variant in vivo: Evidence for a specific functional role of α6A in lymphocyte migration but not in heart development
    • Gimond, C., C. Baudoin, R. van der Neut, D. Kramer, J. Calafat, and A. Sonnenberg. 1998. Cre-loxP-mediated inactivation of the α6A integrin splice variant in vivo: evidence for a specific functional role of α6A in lymphocyte migration but not in heart development. J. Cell Biol. 143:253-266.
    • (1998) J. Cell Biol. , vol.143 , pp. 253-266
    • Gimond, C.1    Baudoin, C.2    Van der Neut, R.3    Kramer, D.4    Calafat, J.5    Sonnenberg, A.6
  • 17
    • 0016815109 scopus 로고
    • Life-span and the inheritance of longevity of inbred mice
    • Goodrick, C.L. 1975. Life-span and the inheritance of longevity of inbred mice. J. Gerontol. 30:257-263.
    • (1975) J. Gerontol. , vol.30 , pp. 257-263
    • Goodrick, C.L.1
  • 18
    • 0021742978 scopus 로고
    • Fibronectin and wound healing
    • Grinnell, F. 1984. Fibronectin and wound healing. J. Cell. Biochem. 26:107-116.
    • (1984) J. Cell. Biochem. , vol.26 , pp. 107-116
    • Grinnell, F.1
  • 19
    • 0025266739 scopus 로고
    • Retroviral expression of alternatively spliced forms of rat fibronectin
    • Guan, J.L., J.E. Trevithick, and R.O. Hynes. 1990. Retroviral expression of alternatively spliced forms of rat fibronectin. J. Cell Biol. 110:833-847.
    • (1990) J. Cell Biol. , vol.110 , pp. 833-847
    • Guan, J.L.1    Trevithick, J.E.2    Hynes, R.O.3
  • 20
    • 0006457649 scopus 로고
    • Identification of a third region of cell-specific alternative splicing in human fibronectin mRNA
    • Gutman, A., and A.R. Kornblihtt. 1987. Identification of a third region of cell-specific alternative splicing in human fibronectin mRNA. Proc. Natl. Acad. Sci. USA. 84:7179-7182.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7179-7182
    • Gutman, A.1    Kornblihtt, A.R.2
  • 23
    • 0004043397 scopus 로고
    • Springer-Verlag New York Inc., New York. 544 pp.
    • Hynes, R.O. 1990. Fibronectins. Springer-Verlag New York Inc., New York. 544 pp.
    • (1990) Fibronectins
    • Hynes, R.O.1
  • 24
    • 0028596335 scopus 로고
    • Expression of variant fibronectins in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis
    • Jarnagin, W.R., D.C. Rockey, V.E. Koteliansky, S.S. Wang, and D.M. Bissell. 1994. Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J. CelI Biol. 127:2037-2048.
    • (1994) J. CelI Biol. , vol.127 , pp. 2037-2048
    • Jarnagin, W.R.1    Rockey, D.C.2    Koteliansky, V.E.3    Wang, S.S.4    Bissell, D.M.5
  • 25
    • 0024114948 scopus 로고
    • Molecular biology of the extracellular matrix proteins
    • Kornblihtt, A.R., and A. Gutman. 1988. Molecular biology of the extracellular matrix proteins. Biol. Rev. Camb. Philos. Soc. 63:465-507.
    • (1988) Biol. Rev. Camb. Philos. Soc. , vol.63 , pp. 465-507
    • Kornblihtt, A.R.1    Gutman, A.2
  • 26
    • 0007600705 scopus 로고
    • Isolation and characterization of cDNA clones for human and bovine fibronectins
    • Kornblihtt, A.R., K. Vibe-Pedersen, and F.E. Baralle. 1983. Isolation and characterization of cDNA clones for human and bovine fibronectins. Proc. Natl. Acad. Sci. USA. 80:3218-3222.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 3218-3222
    • Kornblihtt, A.R.1    Vibe-Pedersen, K.2    Baralle, F.E.3
  • 27
    • 0021299234 scopus 로고
    • Human fibronectin: Molecular cloning evidence for two mRNA species differing by an internal segment coding for a structural domain
    • Kornblihtt, A.R., K. Vibe-Pedersen, and F.E. Baralle. 1984. Human fibronectin: molecular cloning evidence for two mRNA species differing by an internal segment coding for a structural domain. EMBO J. 3:221-226.
    • (1984) EMBO J. , vol.3 , pp. 221-226
    • Kornblihtt, A.R.1    Vibe-Pedersen, K.2    Baralle, F.E.3
  • 29
    • 0016680125 scopus 로고
    • Gerontological data of C57BL/6J mice. I. Sex differences in survival curves
    • Kunstyr, I., and H.G. Leuenberger. 1975. Gerontological data of C57BL/6J mice. I. Sex differences in survival curves. J. Gerontol. 30:157-162.
    • (1975) J. Gerontol. , vol.30 , pp. 157-162
    • Kunstyr, I.1    Leuenberger, H.G.2
  • 30
    • 0035826797 scopus 로고    scopus 로고
    • Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan
    • Kwan, K.Y., and J.C. Wang. 2001. Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan. Proc. Natl. Acad. Sci. USA. 98:5717-5721.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5717-5721
    • Kwan, K.Y.1    Wang, J.C.2
  • 31
    • 0027143943 scopus 로고
    • A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding
    • Lavigueur, A., H. La Branche, A.R. Kornblihtt, and B. Chabot. 1993. A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding. Genes Dev. 7:2405-2417.
    • (1993) Genes Dev. , vol.7 , pp. 2405-2417
    • Lavigueur, A.1    La Branche, H.2    Kornblihtt, A.R.3    Chabot, B.4
  • 32
    • 0035491607 scopus 로고    scopus 로고
    • Conditional control of gene expression in the mouse
    • Lewandoski, M. 2001. Conditional control of gene expression in the mouse. Nat. Rev. Genet. 2:743-755.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 743-755
    • Lewandoski, M.1
  • 33
    • 0037177894 scopus 로고    scopus 로고
    • The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing
    • Liao, Y.F., P.J. Gotwals, V.E. Koteliansky, D. Sheppard, and L. Van De Water. 2002. The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing. J. Biol. Chem. 277:14467-14474.
    • (2002) J. Biol. Chem. , vol.277 , pp. 14467-14474
    • Liao, Y.F.1    Gotwals, P.J.2    Koteliansky, V.E.3    Sheppard, D.4    Van De Water, L.5
  • 34
    • 0031806710 scopus 로고    scopus 로고
    • Alternative splicing of the fibronectin EIIIB exon depends on specific TGCATG repeats
    • Lim, L.P., and P.A. Sharp. 1998. Alternative splicing of the fibronectin EIIIB exon depends on specific TGCATG repeats. Mol. Cell. Biol. 18:3900-3906.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 3900-3906
    • Lim, L.P.1    Sharp, P.A.2
  • 36
    • 0033605295 scopus 로고    scopus 로고
    • Alternatively spliced EDA segment regulates fibronectin-dependent cell cycle progression and mitogenic signal transduction
    • Manabe, R., N. Oh-e, and K. Sekiguchi. 1999. Alternatively spliced EDA segment regulates fibronectin-dependent cell cycle progression and mitogenic signal transduction. J. Biol. Chem. 274:5919-5924.
    • (1999) J. Biol. Chem. , vol.274 , pp. 5919-5924
    • Manabe, R.1    Oh-e, N.2    Sekiguchi, K.3
  • 37
    • 0030753274 scopus 로고    scopus 로고
    • Modulation of cell-adhesive activity of fibronectin by the alternatively spliced EDA segment
    • Manabe, R., N. Ohe, T. Maeda, T. Fukuda, and K. Sekiguchi. 1997. Modulation of cell-adhesive activity of fibronectin by the alternatively spliced EDA segment. J. Cell Biol. 139:295-307.
    • (1997) J. Cell Biol. , vol.139 , pp. 295-307
    • Manabe, R.1    Ohe, N.2    Maeda, T.3    Fukuda, T.4    Sekiguchi, K.5
  • 38
    • 0023652077 scopus 로고
    • A role for exon sequences in alternative splicing of the human fibronectin gene
    • Mardon, H.J., G. Sebastio, and F.E. Baralle. 1987. A role for exon sequences in alternative splicing of the human fibronectin gene. Nucleic Acids Res. 15:7725-7733.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 7725-7733
    • Mardon, H.J.1    Sebastio, G.2    Baralle, F.E.3
  • 39
    • 0032538413 scopus 로고    scopus 로고
    • Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5′ splicing site
    • Muro, A.F., A. Iaconcig, and F.E. Baralle. 1998. Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5′ splicing site. FEBS Lett. 437:137-141.
    • (1998) FEBS Lett. , vol.437 , pp. 137-141
    • Muro, A.F.1    Iaconcig, A.2    Baralle, F.E.3
  • 40
    • 0032913877 scopus 로고    scopus 로고
    • Regulation of fibronectin EDA exon alternative splicing: Possible role of RNA secondary structure for enhancer display
    • Muro, A.F., M. Caputi, R. Pariyarath, F. Pagani, E. Buratti, and F.E. Baralle. 1999. Regulation of fibronectin EDA exon alternative splicing: possible role of RNA secondary structure for enhancer display. Mol. Cell. Biol. 19:2657-2671.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2657-2671
    • Muro, A.F.1    Caputi, M.2    Pariyarath, R.3    Pagani, F.4    Buratti, E.5    Baralle, F.E.6
  • 42
    • 0024550609 scopus 로고
    • Patterns of alternative splicing of fibronectin pre-mRNA in human adult and fetal tissues
    • Oyama, F., Y. Murata, N. Suganuma, T. Kimura, K. Titani, and K. Sekiguchi. 1989. Patterns of alternative splicing of fibronectin pre-mRNA in human adult and fetal tissues. Biochemistry. 28:1428-1434.
    • (1989) Biochemistry , vol.28 , pp. 1428-1434
    • Oyama, F.1    Murata, Y.2    Suganuma, N.3    Kimura, T.4    Titani, K.5    Sekiguchi, K.6
  • 43
    • 0025718766 scopus 로고
    • Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat
    • Pagani, F., L. Zagato, C. Vergani, G. Casari, A. Sidoli, and F.E. Baralle. 1991. Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat. J. Cell Biol. 113:1223-1229.
    • (1991) J. Cell Biol. , vol.113 , pp. 1223-1229
    • Pagani, F.1    Zagato, L.2    Vergani, C.3    Casari, G.4    Sidoli, A.5    Baralle, F.E.6
  • 44
    • 0025372344 scopus 로고
    • Coassembly of plasma and cellular fibronectins into fibrils in human fibroblast cultures
    • Peters, D.M., L.M. Portz, J. Fullenwider, and D.F. Mosher. 1990. Coassembly of plasma and cellular fibronectins into fibrils in human fibroblast cultures. J. Cell Biol. 111:249-256.
    • (1990) J. Cell Biol. , vol.111 , pp. 249-256
    • Peters, D.M.1    Portz, L.M.2    Fullenwider, J.3    Mosher, D.F.4
  • 46
    • 0035099411 scopus 로고    scopus 로고
    • Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis
    • Sakai, T., K.J. Johnson, M. Murozono, K. Sakai, M.A. Magnuson, T. Wieloch, T. Cronberg, A. Isshiki, H.P. Erickson, and R. Fassler. 2001. Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. Nat. Med. 7:324-330.
    • (2001) Nat. Med. , vol.7 , pp. 324-330
    • Sakai, T.1    Johnson, K.J.2    Murozono, M.3    Sakai, K.4    Magnuson, M.A.5    Wieloch, T.6    Cronberg, T.7    Isshiki, A.8    Erickson, H.P.9    Fassler, R.10
  • 48
    • 0021042241 scopus 로고
    • Three different fibronectin mRNAs arise by alternative splicing within the coding region
    • Schwarzbauer, J.E., J.W. Tamkun, I.R. Lemischka, and R.O. Hynes. 1983. Three different fibronectin mRNAs arise by alternative splicing within the coding region. Cell. 35:421-431.
    • (1983) Cell , vol.35 , pp. 421-431
    • Schwarzbauer, J.E.1    Tamkun, J.W.2    Lemischka, I.R.3    Hynes, R.O.4
  • 49
    • 0023409308 scopus 로고
    • Multiple sites of alternative splicing of the rat fibronectin gene transcript
    • Schwarzbauer, J.E., R.S. Patel, D. Fonda, and R.O. Hynes. 1987. Multiple sites of alternative splicing of the rat fibronectin gene transcript. EMBO J. 6:2573-2580.
    • (1987) EMBO J. , vol.6 , pp. 2573-2580
    • Schwarzbauer, J.E.1    Patel, R.S.2    Fonda, D.3    Hynes, R.O.4
  • 50
    • 0024804591 scopus 로고
    • Selective secretion of alternatively spliced fibronectin variants
    • Schwarzbauer, J.E., C.S. Spencer, and C.L. Wilson. 1989. Selective secretion of alternatively spliced fibronectin variants. J. Cell Biol. 109:3445-3453.
    • (1989) J. Cell Biol. , vol.109 , pp. 3445-3453
    • Schwarzbauer, J.E.1    Spencer, C.S.2    Wilson, C.L.3
  • 52
    • 0015788469 scopus 로고
    • Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1 hybrids
    • Smith, G.S., R.L. Walford, and M.R. Mickey. 1973. Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1 hybrids. J. Natl. Cancer Inst. 50:1195-1213.
    • (1973) J. Natl. Cancer Inst. , vol.50 , pp. 1195-1213
    • Smith, G.S.1    Walford, R.L.2    Mickey, M.R.3
  • 53
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteinases regulate cell behavior
    • Sternlicht, M.D., and Z. Werb. 2001. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 17:463-516.
    • (2001) Annu. Rev. Cell Dev. Biol. , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 54
    • 0020569136 scopus 로고
    • Plasma fibronectin is synthesized and secreted by hepatocytes
    • Tamkun, J.W., and R.O. Hynes. 1983. Plasma fibronectin is synthesized and secreted by hepatocytes. J. Biol. Chem. 258:4641-4647.
    • (1983) J. Biol. Chem. , vol.258 , pp. 4641-4647
    • Tamkun, J.W.1    Hynes, R.O.2
  • 56
    • 0026091202 scopus 로고
    • Polarized regulation of fibronectin secretion and alternative splicing by transforming growth factor
    • Wang, A., D.S. Cohen, E. Palmer, and D. Sheppard. 1991. Polarized regulation of fibronectin secretion and alternative splicing by transforming growth factor. J. Biol. Chem. 266:15598-15601.
    • (1991) J. Biol. Chem. , vol.266 , pp. 15598-15601
    • Wang, A.1    Cohen, D.S.2    Palmer, E.3    Sheppard, D.4
  • 57
    • 0034668907 scopus 로고    scopus 로고
    • Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions
    • Wang, Y., R. Xu, T. Sasaoka, S. Tonegawa, M.P. Kung, and E.B. Sankoorikal. 2000. Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions. J. Neurosci. 20:8305-8314.
    • (2000) J. Neurosci. , vol.20 , pp. 8305-8314
    • Wang, Y.1    Xu, R.2    Sasaoka, T.3    Tonegawa, S.4    Kung, M.P.5    Sankoorikal, E.B.6
  • 58
    • 0028903879 scopus 로고
    • Adhesion activity in fibronectin's alternatively spliced domain EDa (EIIIA): Complementarity to plasma fibronectin functions
    • Xia, P., and L.A. Culp. 1995. Adhesion activity in fibronectin's alternatively spliced domain EDa (EIIIA): complementarity to plasma fibronectin functions. Exp. Cell Res. 217:517-527.
    • (1995) Exp. Cell Res. , vol.217 , pp. 517-527
    • Xia, P.1    Culp, L.A.2
  • 59
    • 0036008472 scopus 로고    scopus 로고
    • Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock
    • Yoo, J.Y., D.L. Huso, D. Nathans, and S. Desiderio. 2002. Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock. Cell. 108:331-344.
    • (2002) Cell , vol.108 , pp. 331-344
    • Yoo, J.Y.1    Huso, D.L.2    Nathans, D.3    Desiderio, S.4
  • 60
    • 0023392493 scopus 로고
    • Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon
    • Zardi, L., B. Carnemolla, A. Siri, T.E. Petersen, G. Paolella, G. Sebastio, and F.E. Baralle. 1987. Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon. EMBO J. 6:2337-2342.
    • (1987) EMBO J. , vol.6 , pp. 2337-2342
    • Zardi, L.1    Carnemolla, B.2    Siri, A.3    Petersen, T.E.4    Paolella, G.5    Sebastio, G.6    Baralle, F.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.