Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: Possible risk factors in the Alzheimer's-type neurodegenerative pathways

Journal of Neurochemistry

Volumn 76, Issue 5, 2001, Pages 1509-1520

  White, Anthony R ^a   Huang, Xudong ^b   Jobling, Michael F ^c   Barrow, Colin J ^a   Beyreuther, Konrad ^d   Masters, Colin L ^a   Bush, Ashley I ^a   Cappai, Roberto ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cell culture; Dementia; Folate deficiency; Neurodegeneration; Transition metals

Indexed keywords

AMYLOID BETA PROTEIN; COPPER; HOMOCYSTEINE; HYDROGEN PEROXIDE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL LOSS; CELL MEMBRANE PERMEABILITY; ENDOTHELIUM CELL; FOLIC ACID DEFICIENCY; HYPERHOMOCYSTEINEMIA; MOLECULAR INTERACTION; MOUSE; NERVE CELL CULTURE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RISK FACTOR;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; HOMOCYSTEINE; HUMANS; KINETICS; MICE; MICE, INBRED STRAINS; NEURONS; NEUROTOXINS; RISK FACTORS;

ANIMALIA;

EID: 0035093878     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00178.x     Document Type: Article

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