메뉴 건너뛰기




Volumn 67, Issue 3, 1996, Pages 1328-1331

Brain S-adenosylmethionine levels are severely decreased in Alzheimer's disease

Author keywords

Alzheimer's disease; Brain; S Adenosylhomocysteine; S Adenosylmethionine

Indexed keywords

METHIONINE ADENOSYLTRANSFERASE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

EID: 0029799427     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67031328.x     Document Type: Article
Times cited : (250)

References (21)
  • 1
    • 0028961549 scopus 로고
    • Increased immunostaining for L-ornithine decarboxylase occurs in neocortical neurons of Alzheimer's disease patients
    • Bernstein H.-G. and Muller M. (1995) Increased immunostaining for L-ornithine decarboxylase occurs in neocortical neurons of Alzheimer's disease patients. Neurosci. Lett. 186, 123-126.
    • (1995) Neurosci. Lett. , vol.186 , pp. 123-126
    • Bernstein, H.-G.1    Muller, M.2
  • 2
    • 0025606597 scopus 로고
    • Cerebrospinal fluid S-adenosylmethionine in depression and dementia: Effects of treatment with parenteral and oral S-adenosylmethionine
    • Bottiglieri T., Godfrey P., Flynn T., Carney M. W. P., Toone B. K., and Reynolds E. H. (1990) Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine. J. Neurol. Neurosurg. Psychiatry 53, 1096-1098.
    • (1990) J. Neurol. Neurosurg. Psychiatry , vol.53 , pp. 1096-1098
    • Bottiglieri, T.1    Godfrey, P.2    Flynn, T.3    Carney, M.W.P.4    Toone, B.K.5    Reynolds, E.H.6
  • 3
    • 0028102526 scopus 로고
    • The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders
    • Bottiglieri T., Hyland K., and Reynolds E. H. (1994) The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders. Drugs 48, 137-152.
    • (1994) Drugs , vol.48 , pp. 137-152
    • Bottiglieri, T.1    Hyland, K.2    Reynolds, E.H.3
  • 5
    • 0027269678 scopus 로고
    • Folates and psychiatric disorders
    • Crelin R., Bottiglieri T., and Reynolds E. H. (1993) Folates and psychiatric disorders. Drugs 45, 623-636.
    • (1993) Drugs , vol.45 , pp. 623-636
    • Crelin, R.1    Bottiglieri, T.2    Reynolds, E.H.3
  • 6
    • 0023614366 scopus 로고
    • S-Adenosylmethionine in the treatment of osteoarthritis: Review of the clinical studies
    • Di Padova C. (1987) S-Adenosylmethionine in the treatment of osteoarthritis: review of the clinical studies. Am. J. Med. 83 (Suppl. 5), 60-65.
    • (1987) Am. J. Med. , vol.83 , Issue.5 SUPPL. , pp. 60-65
    • Di Padova, C.1
  • 7
    • 0024342257 scopus 로고
    • 5-Adenosyl-L-methionine: A review of its pharmacological properties and therapeutic potential in liver dysfunction and affective disorders in relation to its physiological role in cell metabolism
    • Friedel H. A., Goa K. L., and Benfield P. (1989) 5-Adenosyl-L-methionine: a review of its pharmacological properties and therapeutic potential in liver dysfunction and affective disorders in relation to its physiological role in cell metabolism. Drugs 38, 389-416.
    • (1989) Drugs , vol.38 , pp. 389-416
    • Friedel, H.A.1    Goa, K.L.2    Benfield, P.3
  • 8
    • 0025312343 scopus 로고
    • Oral S-adenosylmethionine in depression: A randomized, double-blind, placebo-controlled trial
    • Kagan B. L., Sultzer D. L., Rosenlicht N., and Gerner R. H. (1990) Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am. J. Psychiatry 147, 591-595.
    • (1990) Am. J. Psychiatry , vol.147 , pp. 591-595
    • Kagan, B.L.1    Sultzer, D.L.2    Rosenlicht, N.3    Gerner, R.H.4
  • 9
    • 0025805370 scopus 로고
    • Evidence of brain methyltransferase inhibition and early brain involvement in HIV-positive patients
    • Keating J. N., Trimble K. C., Mulcahy F., Scott J. M., and Weir D. G. (1991) Evidence of brain methyltransferase inhibition and early brain involvement in HIV-positive patients. Lancet 337, 935-939.
    • (1991) Lancet , vol.337 , pp. 935-939
    • Keating, J.N.1    Trimble, K.C.2    Mulcahy, F.3    Scott, J.M.4    Weir, D.G.5
  • 10
    • 0024494558 scopus 로고
    • S-Adenosyl-L-methionine ameliorates ischemic brain metabolism in spontaneously hypertensive rats
    • Kozuka M. and Iwata N. (1989) S-Adenosyl-L-methionine ameliorates ischemic brain metabolism in spontaneously hypertensive rats. Jpn. J. Pharmacol 49, 173-179.
    • (1989) Jpn. J. Pharmacol , vol.49 , pp. 173-179
    • Kozuka, M.1    Iwata, N.2
  • 11
    • 0023905830 scopus 로고
    • Modulation of polyamine-biosynthetic activity by S-adenosylmethionine depletion
    • Kramer D. L., Sufrin J. R., and Porter C. W. (1988) Modulation of polyamine-biosynthetic activity by S-adenosylmethionine depletion. Biochem. J. 249, 581-586.
    • (1988) Biochem. J. , vol.249 , pp. 581-586
    • Kramer, D.L.1    Sufrin, J.R.2    Porter, C.W.3
  • 12
    • 0028894129 scopus 로고
    • An abnormal methylation ratio induces hypomethylation in vitro in the brain of the pig and man, but not in the rat
    • McKeever M., Molloy A., Young P., Kennedy S., Kennedy D. G., Scott J. M., and Weir D. G. (1995a) An abnormal methylation ratio induces hypomethylation in vitro in the brain of the pig and man, but not in the rat. Clin. Sci. 88, 73-79.
    • (1995) Clin. Sci. , vol.88 , pp. 73-79
    • McKeever, M.1    Molloy, A.2    Young, P.3    Kennedy, S.4    Kennedy, D.G.5    Scott, J.M.6    Weir, D.G.7
  • 14
    • 0027447346 scopus 로고
    • Pathogenesis of cobalamin neuropathy: Deficiency of nervous system 5-adenosylmethionine
    • Metz J. (1993) Pathogenesis of cobalamin neuropathy: deficiency of nervous system 5-adenosylmethionine. Nutr. Rev. 51, 12-15.
    • (1993) Nutr. Rev. , vol.51 , pp. 12-15
    • Metz, J.1
  • 15
    • 0029051691 scopus 로고
    • Brain polyamine levels are altered in Alzheimer's disease
    • Morrison L. D. and Kish S. J. (1995) Brain polyamine levels are altered in Alzheimer's disease. Neurosci. Lett. 197, 5-8.
    • (1995) Neurosci. Lett. , vol.197 , pp. 5-8
    • Morrison, L.D.1    Kish, S.J.2
  • 16
    • 0027254187 scopus 로고
    • Brain S-adenosylmethionine decarboxylase activity is increased in Alzheimer's disease
    • Morrison L. D., Bergeron C., and Kish S. J. (1993) Brain S-adenosylmethionine decarboxylase activity is increased in Alzheimer's disease. Neurosci. Lett. 154, 141-144.
    • (1993) Neurosci. Lett. , vol.154 , pp. 141-144
    • Morrison, L.D.1    Bergeron, C.2    Kish, S.J.3
  • 18
    • 0023863363 scopus 로고
    • 5-Adenosyl-L-methionine protects the hippocampal CA1 neurons from the ischemic neuronal death in rat
    • Sato H., Hariyama H., and Moriguchi K. (1988) 5-Adenosyl-L-methionine protects the hippocampal CA1 neurons from the ischemic neuronal death in rat. Biochem. Biophys. Res. Commun. 150, 491-496.
    • (1988) Biochem. Biophys. Res. Commun. , vol.150 , pp. 491-496
    • Sato, H.1    Hariyama, H.2    Moriguchi, K.3
  • 20
    • 0028657637 scopus 로고
    • Brain ATP:L-methionine S-adenosyltransferase (MAT), S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH): Regional distribution and age-related changes
    • Troliin C. G., Lofberg C., Trolin G., and Oreland L. (1994) Brain ATP:L-methionine S-adenosyltransferase (MAT), S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH): regional distribution and age-related changes. Eur. Neuropsychopharmacol. 4, 469-477.
    • (1994) Eur. Neuropsychopharmacol. , vol.4 , pp. 469-477
    • Troliin, C.G.1    Lofberg, C.2    Trolin, G.3    Oreland, L.4
  • 21
    • 0025011401 scopus 로고
    • Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias
    • Yates C. M., Butterworth J., Tennant M. C., and Gordon A. (1990) Enzyme activities in relation to pH and lactate in postmortem brain in Alzheimer-type and other dementias. J. Neurochem. 55, 1624-1630.
    • (1990) J. Neurochem. , vol.55 , pp. 1624-1630
    • Yates, C.M.1    Butterworth, J.2    Tennant, M.C.3    Gordon, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.