Apolipoprotein Eε4 modifies Alzheimer's disease onset in an E280A PS1 kindred

Annals of Neurology

Volumn 54, Issue 2, 2003, Pages 163-169

  Pastor, Pau ^a   Roe, Catherine M ^a   Villegas, Andrés ^b   Bedoya, Gabriel ^b   Chakraverty, Sumi ^a   García, Gloria ^b   Tirado, Victoria ^b   Norton, Joanne ^a   Ríos, Silvia ^b   Martínez, Maribel ^a   Kosik, Kenneth S ^c   Lopera, Francisco ^b   Goate, Alison M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSIDAD DE ANTIOQUIA   (Colombia)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E EPSILON4; APOLIPOPROTEIN E4; PRESENILIN 1; PRESENILIN 1 E280A; UNCLASSIFIED DRUG; APOLIPOPROTEIN E; DNA; MEMBRANE PROTEIN; PSEN1 PROTEIN, HUMAN;

ADULT; ALLELE; ALZHEIMER DISEASE; APOE GENE; ARTICLE; COLOMBIA; CONFIDENCE INTERVAL; CONTROLLED STUDY; COX PROPORTIONAL HAZARD MODEL; DISEASE ASSOCIATION; DISEASE DURATION; DNA DETERMINATION; EDUCATION; ENVIRONMENTAL FACTOR; FAMILIAL DISEASE; FEMALE; GENE MUTATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HETEROZYGOTE; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RURAL AREA; STATISTICAL ANALYSIS; STATISTICAL MODEL; AGED; ENVIRONMENT; GENETICS; MIDDLE AGED; MUTATION; NON-PROGRAMMATIC; PATHOLOGY; PEDIGREE; PHYSIOLOGY; RURAL POPULATION; SURVIVAL;

NON-PROGRAMMATIC;

ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; COLOMBIA; DNA; EDUCATION; ENVIRONMENT; FEMALE; HETEROZYGOTE; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION; PEDIGREE; PHENOTYPE; POLYMORPHISM, GENETIC; PRESENILIN-1; PROMOTER REGIONS (GENETICS); RURAL POPULATION; SURVIVAL ANALYSIS;

EID: 0041865226     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.10636     Document Type: Article

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