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Volumn 262, Issue 1, 2007, Pages 26-43

Inhibition of HIV-1 entry by antibodies: Potential viral and cellular targets

Author keywords

Envelope glycoprotein; HIV 1; Incorporated proteins; Neutralizing antibodies; Receptors; Vaccine

Indexed keywords

12G5; 5A8; ANTIBODY; CD4 ANTIGEN; CD4 IMMUNOGLOBULIN G2; CELL PROTEIN; CELL RECEPTOR; CHEMOKINE RECEPTOR CCR5; CYANOVIRIN N; GLYCOPROTEIN GP 120; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HUMAN IMMUNODEFICIENCY VIRUS 1 VACCINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MAB 004; NEUTRALIZING ANTIBODY; PHOSPHORYL LIPID A; PRO 140; Q 425; TNX 355; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS RECEPTOR;

EID: 34347256384     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2007.01820.x     Document Type: Conference Paper
Times cited : (41)

References (154)
  • 1
    • 0025331727 scopus 로고
    • Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160
    • Berman PW, Gregory TJ, Riddle L et al. Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160. Nature 1990 345 : 622 5.
    • (1990) Nature , vol.345 , pp. 622-5
    • Berman, P.W.1    Gregory, T.J.2    Riddle, L.3
  • 2
    • 0037137509 scopus 로고    scopus 로고
    • Do not underestimate the power of antibodies - Lessons from adoptive transfer of antibodies against HIV
    • Ferrantelli F, Rasmussen RA, Hofmann-Lehmann R, Xu W, McClure HM, Ruprecht RM. Do not underestimate the power of antibodies - lessons from adoptive transfer of antibodies against HIV. Vaccine 2002 20 (Suppl. 4) : A61 5.
    • (2002) Vaccine , vol.20 , Issue.4
    • Ferrantelli, F.1    Rasmussen, R.A.2    Hofmann-Lehmann, R.3    Xu, W.4    McClure, H.M.5    Ruprecht, R.M.6
  • 3
    • 0034904087 scopus 로고    scopus 로고
    • Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge
    • Hofmann-Lehmann R, Vlasak J, Rasmussen RA et al. Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge. J Virol 2001 75 : 7470 80.
    • (2001) J Virol , vol.75 , pp. 7470-80
    • Hofmann-Lehmann, R.1    Vlasak, J.2    Rasmussen, R.A.3
  • 4
    • 0032947286 scopus 로고    scopus 로고
    • Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies
    • Mascola JR, Lewis MG, Stiegler G et al. Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies. J Virol 1999 73 : 4009 18.
    • (1999) J Virol , vol.73 , pp. 4009-18
    • Mascola, J.R.1    Lewis, M.G.2    Stiegler, G.3
  • 5
    • 0033951746 scopus 로고    scopus 로고
    • Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
    • Mascola JR, Stiegler G, VanCott TC et al. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med 2000 6 : 207 10.
    • (2000) Nat Med , vol.6 , pp. 207-10
    • Mascola, J.R.1    Stiegler, G.2    Vancott, T.C.3
  • 6
    • 0345471066 scopus 로고    scopus 로고
    • Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
    • Veazey RS, Shattock RJ, Pope M et al. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nat Med 2003 9 : 343 6.
    • (2003) Nat Med , vol.9 , pp. 343-6
    • Veazey, R.S.1    Shattock, R.J.2    Pope, M.3
  • 7
    • 0037849954 scopus 로고    scopus 로고
    • Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia
    • Lazzarin A, Clotet B, Cooper D et al. Efficacy of enfuvirtide in patients infected with drug-resistant HIV-1 in Europe and Australia. N Engl J Med 2003 348 : 2186 95.
    • (2003) N Engl J Med , vol.348 , pp. 2186-95
    • Lazzarin, A.1    Clotet, B.2    Cooper, D.3
  • 8
    • 3242769788 scopus 로고    scopus 로고
    • Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques
    • Hazuda DJ, Young SD, Guare JP et al. Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques. Science 2004 305 : 528 32.
    • (2004) Science , vol.305 , pp. 528-32
    • Hazuda, D.J.1    Young, S.D.2    Guare, J.P.3
  • 9
    • 28544434492 scopus 로고    scopus 로고
    • CCR5 antagonists: Host-targeted antivirals for the treatment of HIV infection
    • Westby M, van der Ryst E. CCR5 antagonists: host-targeted antivirals for the treatment of HIV infection. Antivir Chem Chemother 2005 16 : 339 54.
    • (2005) Antivir Chem Chemother , vol.16 , pp. 339-54
    • Westby, M.1    Van Der Ryst, E.2
  • 10
    • 9144236197 scopus 로고    scopus 로고
    • Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1
    • Kuritzkes DR, Jacobson J, Powderly WG et al. Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1. J Infect Dis 2004 189 : 286 91.
    • (2004) J Infect Dis , vol.189 , pp. 286-91
    • Kuritzkes, D.R.1    Jacobson, J.2    Powderly, W.G.3
  • 11
    • 0032902710 scopus 로고    scopus 로고
    • Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5
    • Olson WC, Rabut GE, Nagashima KA et al. Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5. J Virol 1999 73 : 4145 55.
    • (1999) J Virol , vol.73 , pp. 4145-55
    • Olson, W.C.1    Rabut, G.E.2    Nagashima, K.A.3
  • 12
    • 0033515588 scopus 로고    scopus 로고
    • Epitope mapping of CCRS reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function
    • Lee BM, Sharron C, Blanpain BJ et al. Epitope mapping of CCRS reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J Biol Chem 1999 274 : 9617 26.
    • (1999) J Biol Chem , vol.274 , pp. 9617-26
    • Lee, B.M.1    Sharron, C.2    Blanpain, B.J.3
  • 14
    • 0032577550 scopus 로고    scopus 로고
    • HIV entry and its inhibition
    • Chan DC, Kim PS. HIV entry and its inhibition. Cell 1998 93 : 681 4.
    • (1998) Cell , vol.93 , pp. 681-4
    • Chan, D.C.1    Kim, P.S.2
  • 15
    • 1242319460 scopus 로고    scopus 로고
    • Promoting trimerization of soluble human immunodeficiency virus type 1 (HIV-1) Env through the use of HIV-1/simian immunodeficiency virus chimeras
    • Center RJ, Lebowitz J, Leapman RD, Moss B. Promoting trimerization of soluble human immunodeficiency virus type 1 (HIV-1) Env through the use of HIV-1/simian immunodeficiency virus chimeras. J Virol 2004 78 : 2265 76.
    • (2004) J Virol , vol.78 , pp. 2265-76
    • Center, R.J.1    Lebowitz, J.2    Leapman, R.D.3    Moss, B.4
  • 16
    • 0035910036 scopus 로고    scopus 로고
    • Oligomeric structure of virion-associated and soluble forms of the simian immunodeficiency virus envelope protein in the prefusion activated conformation
    • Center RJ, Schuck P, Leapman RD et al. Oligomeric structure of virion-associated and soluble forms of the simian immunodeficiency virus envelope protein in the prefusion activated conformation. Proc Natl Acad Sci U S A 2001 98 : 14877 82.
    • (2001) Proc Natl Acad Sci U S a , vol.98 , pp. 14877-82
    • Center, R.J.1    Schuck, P.2    Leapman, R.D.3
  • 17
    • 0036091692 scopus 로고    scopus 로고
    • Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU). Is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus
    • Chertova E, Bess JW Jr., Crise BJ et al. Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU). Is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus. J Virol 2002 76 : 5315 25.
    • (2002) J Virol , vol.76 , pp. 5315-25
    • Chertova, E.1    Bess Jr., J.W.2    Crise, B.J.3
  • 18
    • 0032546844 scopus 로고    scopus 로고
    • The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens
    • Wyatt R, Sodroski J. The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. Science 1998 280 : 1884 8.
    • (1998) Science , vol.280 , pp. 1884-8
    • Wyatt, R.1    Sodroski, J.2
  • 19
    • 33748038359 scopus 로고    scopus 로고
    • Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ
    • Zanetti G, Briggs JA, Grunewald K, Sattentau QJ, Fuller SD. Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ. PLoS Pathog 2006 2 : e83.
    • (2006) PLoS Pathog , vol.2
    • Zanetti, G.1    Briggs, J.A.2    Grunewald, K.3    Sattentau, Q.J.4    Fuller, S.D.5
  • 20
    • 33745203490 scopus 로고    scopus 로고
    • Distribution and three-dimensional structure of AIDS virus envelope spikes
    • Zhu P, Liu J, Bess J Jr. et al. Distribution and three-dimensional structure of AIDS virus envelope spikes. Nature 2006 441 : 847 52.
    • (2006) Nature , vol.441 , pp. 847-52
    • Zhu, P.1    Liu, J.2    Bess Jr., J.3
  • 21
    • 9044241681 scopus 로고    scopus 로고
    • Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
    • Trkola A, Purtscher M, Muster T et al. Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1. J Virol 1996 70 : 1100 8.
    • (1996) J Virol , vol.70 , pp. 1100-8
    • Trkola, A.1    Purtscher, M.2    Muster, T.3
  • 22
    • 0037456827 scopus 로고    scopus 로고
    • Antibody neutralization and escape by HIV-1
    • Wei X, Decker JM, Wang S et al. Antibody neutralization and escape by HIV-1. Nature 2003 422 : 307 12.
    • (2003) Nature , vol.422 , pp. 307-12
    • Wei, X.1    Decker, J.M.2    Wang, S.3
  • 23
    • 0043080631 scopus 로고
    • Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees
    • Goudsmit J, Debouck C, Meloen RH et al. Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees. Proc Natl Acad Sci U S A 1988 85 : 4478 82.
    • (1988) Proc Natl Acad Sci U S a , vol.85 , pp. 4478-82
    • Goudsmit, J.1    Debouck, C.2    Meloen, R.H.3
  • 24
    • 0037069682 scopus 로고    scopus 로고
    • HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
    • Kwong PD, Doyle ML, Casper DJ et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites. Nature 2002 420 : 678 82.
    • (2002) Nature , vol.420 , pp. 678-82
    • Kwong, P.D.1    Doyle, M.L.2    Casper, D.J.3
  • 25
    • 0030043169 scopus 로고    scopus 로고
    • Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein
    • Moore JP, Sodroski J. Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein. J Virol 1996 70 : 1863 72.
    • (1996) J Virol , vol.70 , pp. 1863-72
    • Moore, J.P.1    Sodroski, J.2
  • 26
    • 0030730243 scopus 로고    scopus 로고
    • Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein
    • Wyatt R, Desjardin E, Olshevsky U et al. Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein. J Virol 1997 71 : 9722 31.
    • (1997) J Virol , vol.71 , pp. 9722-31
    • Wyatt, R.1    Desjardin, E.2    Olshevsky, U.3
  • 27
    • 1342332108 scopus 로고    scopus 로고
    • Public health. a sound rationale needed for phase III HIV-1 vaccine trials
    • Burton DR, Desrosiers RC, Doms RW et al. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science 2004 303 : 316.
    • (2004) Science , vol.303 , pp. 316
    • Burton, D.R.1    Desrosiers, R.C.2    Doms, R.W.3
  • 28
    • 13944262072 scopus 로고    scopus 로고
    • Lessons from failure - Preparing for future HIV-1 vaccine efficacy trials
    • Graham BS, Mascola JR. Lessons from failure - preparing for future HIV-1 vaccine efficacy trials. J Infect Dis 2005 191 : 647 9.
    • (2005) J Infect Dis , vol.191 , pp. 647-9
    • Graham, B.S.1    Mascola, J.R.2
  • 29
    • 0042127158 scopus 로고    scopus 로고
    • HIV gp120 vaccine - VaxGen; AIDSVAX, AIDSVAX B/B, AIDSVAX B/E, HIV gp120 vaccine - Genentech; HIV gp120 vaccine AIDSVAX - VaxGen; HIV vaccine AIDSVAX - VaxGen
    • Ltd, A. I.
    • Ltd, A. I. HIV gp120 vaccine - VaxGen; AIDSVAX, AIDSVAX B/B, AIDSVAX B/E, HIV gp120 vaccine - Genentech; HIV gp120 vaccine AIDSVAX - VaxGen; HIV vaccine AIDSVAX - VaxGen. Drugs R D 2003 4 : 249 53.
    • (2003) Drugs R D , vol.4 , pp. 249-53
  • 30
    • 33846172297 scopus 로고    scopus 로고
    • Rational modification of HIV-1 envelope glycoproteins for immunogen design
    • Phogat S, Wyatt R. Rational modification of HIV-1 envelope glycoproteins for immunogen design. Curr Pharm Des 2007 13 : 213 27.
    • (2007) Curr Pharm des , vol.13 , pp. 213-27
    • Phogat, S.1    Wyatt, R.2
  • 31
    • 0032543555 scopus 로고    scopus 로고
    • The antigenic structure of the HIV gp120 envelope glycoprotein
    • Wyatt R, Kwong PD, Desjardins E et al. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature 1998 393 : 705 11.
    • (1998) Nature , vol.393 , pp. 705-11
    • Wyatt, R.1    Kwong, P.D.2    Desjardins, E.3
  • 32
    • 1542317452 scopus 로고    scopus 로고
    • HIV vaccine design and the neutralizing antibody problem
    • Burton DR, Desrosiers RC, Doms RW et al. HIV vaccine design and the neutralizing antibody problem. Nat Immunol 2004 5 : 233 6.
    • (2004) Nat Immunol , vol.5 , pp. 233-6
    • Burton, D.R.1    Desrosiers, R.C.2    Doms, R.W.3
  • 33
    • 0027985431 scopus 로고
    • Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
    • Burton DR, Pyati J, Koduri R et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 1994 266 : 1024 7.
    • (1994) Science , vol.266 , pp. 1024-7
    • Burton, D.R.1    Pyati, J.2    Koduri, R.3
  • 34
    • 0027458347 scopus 로고
    • Neutralization of HIV-1 by F105, a human monoclonal antibody to the CD4 binding site of gp120
    • Posner MR, Cavacini LA, Emes CL, Power J, Byrn R. Neutralization of HIV-1 by F105, a human monoclonal antibody to the CD4 binding site of gp120. J Acquir Immune Defic Syndr 1993 6 : 7 14.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 7-14
    • Posner, M.R.1    Cavacini, L.A.2    Emes, C.L.3    Power, J.4    Byrn, R.5
  • 35
    • 34347231142 scopus 로고    scopus 로고
    • Functional constraints and antibody recognition of the CD4-binding site on HIV-1 gp120
    • Kwong PD, Zhou T, Xu L et al. Functional constraints and antibody recognition of the CD4-binding site on HIV-1 gp120. Antiviral Ther 2006 11 : 159.
    • (2006) Antiviral Ther , vol.11 , pp. 159
    • Kwong, P.D.1    Zhou, T.2    Xu, L.3
  • 36
    • 12444291017 scopus 로고    scopus 로고
    • Antibody domain exchange is an immunological solution to carbohydrate cluster recognition
    • Calarese DA, Scanlan CN, Zwick MB et al. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science 2003 300 : 2065 71.
    • (2003) Science , vol.300 , pp. 2065-71
    • Calarese, D.A.1    Scanlan, C.N.2    Zwick, M.B.3
  • 37
    • 0027378573 scopus 로고
    • A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
    • Muster T, Steindl F, Purtscher M et al. A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J Virol 1993 67 : 6642 7.
    • (1993) J Virol , vol.67 , pp. 6642-7
    • Muster, T.1    Steindl, F.2    Purtscher, M.3
  • 38
    • 0034759882 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
    • Zwick MB, Labrijn AF, Wang M et al. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J Virol 2001 75 : 10892 905.
    • (2001) J Virol , vol.75 , pp. 10892-905
    • Zwick, M.B.1    Labrijn, A.F.2    Wang, M.3
  • 39
    • 4544379899 scopus 로고    scopus 로고
    • Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
    • Ofek G, Tang M, Sambor A et al. Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope. J Virol 2004 78 : 10724 37.
    • (2004) J Virol , vol.78 , pp. 10724-37
    • Ofek, G.1    Tang, M.2    Sambor, A.3
  • 40
    • 13844255333 scopus 로고    scopus 로고
    • Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41
    • Cardoso RM, Zwick MB, Stanfield RL et al. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity 2005 22 : 163 73.
    • (2005) Immunity , vol.22 , pp. 163-73
    • Cardoso, R.M.1    Zwick, M.B.2    Stanfield, R.L.3
  • 41
    • 26844448487 scopus 로고    scopus 로고
    • A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope
    • Miller MD, Geleziunas R, Bianchi E et al. A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope. Proc Natl Acad Sci U S A 2005 102 : 14759 64.
    • (2005) Proc Natl Acad Sci U S a , vol.102 , pp. 14759-64
    • Miller, M.D.1    Geleziunas, R.2    Bianchi, E.3
  • 42
    • 21744447837 scopus 로고    scopus 로고
    • Immunology. Close to the edge: Neutralizing the HIV-1 envelope
    • Nabel GJ. Immunology. Close to the edge: neutralizing the HIV-1 envelope. Science 2005 308 : 1878 9.
    • (2005) Science , vol.308 , pp. 1878-9
    • Nabel, G.J.1
  • 43
    • 0033952103 scopus 로고    scopus 로고
    • Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
    • Baba TW, Liska V, Hofmann-Lehmann R et al. Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med 2000 6 : 200 6.
    • (2000) Nat Med , vol.6 , pp. 200-6
    • Baba, T.W.1    Liska, V.2    Hofmann-Lehmann, R.3
  • 44
    • 33646371737 scopus 로고    scopus 로고
    • This is no time to stop use of nevarapine to prevent mother-to-child transmission of HIV
    • Oleske JM. This is no time to stop use of nevarapine to prevent mother-to-child transmission of HIV. AIDS 2006 20 : 1059 60.
    • (2006) AIDS , vol.20 , pp. 1059-60
    • Oleske, J.M.1
  • 45
    • 20944446452 scopus 로고    scopus 로고
    • Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
    • Trkola A, Kuster H, Rusert P et al. Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat Med 2005 11 : 615 22.
    • (2005) Nat Med , vol.11 , pp. 615-22
    • Trkola, A.1    Kuster, H.2    Rusert, P.3
  • 46
    • 0345166103 scopus 로고    scopus 로고
    • Transfer of neutralizing IgG to macaques 6 h but not 24 h after SHIV infection confers sterilizing protection: Implications for HIV-1 vaccine development
    • Nishimura Y, Igarashi T, Haigwood NL et al. Transfer of neutralizing IgG to macaques 6 h but not 24 h after SHIV infection confers sterilizing protection: implications for HIV-1 vaccine development. Proc Natl Acad Sci U S A 2003 100 : 15131 6.
    • (2003) Proc Natl Acad Sci U S a , vol.100 , pp. 15131-6
    • Nishimura, Y.1    Igarashi, T.2    Haigwood, N.L.3
  • 47
    • 0036720793 scopus 로고    scopus 로고
    • Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades
    • Gorny MK, Williams C, Volsky B et al. Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades. J Virol 2002 76 : 9035 45.
    • (2002) J Virol , vol.76 , pp. 9035-45
    • Gorny, M.K.1    Williams, C.2    Volsky, B.3
  • 49
    • 27744597054 scopus 로고    scopus 로고
    • Structure of a V3-containing HIV-1 gp120 core
    • Huang CC, Tang M, Zhang MY et al. Structure of a V3-containing HIV-1 gp120 core. Science 2005 310 : 1025 8.
    • (2005) Science , vol.310 , pp. 1025-8
    • Huang, C.C.1    Tang, M.2    Zhang, M.Y.3
  • 50
    • 0027256814 scopus 로고
    • Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding
    • Thali M, Moore JP, Furman C et al. Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding. J Virol 1993 67 : 3978 88.
    • (1993) J Virol , vol.67 , pp. 3978-88
    • Thali, M.1    Moore, J.P.2    Furman, C.3
  • 51
    • 0037213286 scopus 로고    scopus 로고
    • CD4 binding site antibodies inhibit human immunodeficiency virus gp120 envelope glycoprotein interaction with CCR5
    • Raja A, Venturi M, Kwong P, Sodroski J. CD4 binding site antibodies inhibit human immunodeficiency virus gp120 envelope glycoprotein interaction with CCR5. J Virol 2003 77 : 713 8.
    • (2003) J Virol , vol.77 , pp. 713-8
    • Raja, A.1    Venturi, M.2    Kwong, P.3    Sodroski, J.4
  • 52
    • 0037076265 scopus 로고    scopus 로고
    • Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes
    • Moulard M, Phogat SK, Shu Y et al. Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes. Proc Natl Acad Sci U S A 2002 99 : 6913 8.
    • (2002) Proc Natl Acad Sci U S a , vol.99 , pp. 6913-8
    • Moulard, M.1    Phogat, S.K.2    Shu, Y.3
  • 53
    • 0141521564 scopus 로고    scopus 로고
    • Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1
    • Labrijn AF, Poignard P, Raja A et al. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1. J Virol 2003 77 : 10557 65.
    • (2003) J Virol , vol.77 , pp. 10557-65
    • Labrijn, A.F.1    Poignard, P.2    Raja, A.3
  • 54
    • 20844448731 scopus 로고    scopus 로고
    • Antigenic conservation and immunogenicity of the HIV coreceptor binding site
    • Decker JM, Bibollet-Ruche F, Wei X et al. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. J Exp Med 2005 201 : 1407 19.
    • (2005) J Exp Med , vol.201 , pp. 1407-19
    • Decker, J.M.1    Bibollet-Ruche, F.2    Wei, X.3
  • 55
    • 29244474887 scopus 로고    scopus 로고
    • HIV vaccine design: Insights from live attenuated SIV vaccines
    • Koff WC, Johnson PR, Watkins DI et al. HIV vaccine design: insights from live attenuated SIV vaccines. Nat Immunol 2006 7 : 19 23.
    • (2006) Nat Immunol , vol.7 , pp. 19-23
    • Koff, W.C.1    Johnson, P.R.2    Watkins, D.I.3
  • 57
    • 0034087050 scopus 로고    scopus 로고
    • Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins
    • Yang X, Farzan M, Wyatt R, Sodroski J. Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins. J Virol 2000 74 : 5716 25.
    • (2000) J Virol , vol.74 , pp. 5716-25
    • Yang, X.1    Farzan, M.2    Wyatt, R.3    Sodroski, J.4
  • 58
    • 0036231093 scopus 로고    scopus 로고
    • Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin
    • Yang X, Lee J, Mahony EM, Kwong PD, Wyatt R, Sodroski J. Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin. J Virol 2002 76 : 4634 42.
    • (2002) J Virol , vol.76 , pp. 4634-42
    • Yang, X.1    Lee, J.2    Mahony, E.M.3    Kwong, P.D.4    Wyatt, R.5    Sodroski, J.6
  • 59
    • 0033985999 scopus 로고    scopus 로고
    • A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure
    • Binley JM, Sanders RW, Clas B et al. A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure. J Virol 2000 74 : 627 43.
    • (2000) J Virol , vol.74 , pp. 627-43
    • Binley, J.M.1    Sanders, R.W.2    Clas, B.3
  • 60
    • 0037018921 scopus 로고    scopus 로고
    • Conserved structures exposed in HIV-1 envelope glycoproteins stabilized by flexible linkers as potent entry inhibitors and potential immunogens
    • Chow YH, Wei OL, Phogat S et al. Conserved structures exposed in HIV-1 envelope glycoproteins stabilized by flexible linkers as potent entry inhibitors and potential immunogens. Biochemistry 2002 41 : 7176 82.
    • (2002) Biochemistry , vol.41 , pp. 7176-82
    • Chow, Y.H.1    Wei, O.L.2    Phogat, S.3
  • 61
    • 0037321708 scopus 로고    scopus 로고
    • Changes in the immunogenic properties of soluble gp140 human immunodeficiency virus envelope constructs upon partial deletion of the second hypervariable region
    • Srivastava IK, VanDorsten K, Vojtech L, Barnett SW, Stamatatos L. Changes in the immunogenic properties of soluble gp140 human immunodeficiency virus envelope constructs upon partial deletion of the second hypervariable region. J Virol 2003 77 : 2310 20.
    • (2003) J Virol , vol.77 , pp. 2310-20
    • Srivastava, I.K.1    Vandorsten, K.2    Vojtech, L.3    Barnett, S.W.4    Stamatatos, L.5
  • 62
    • 0036096976 scopus 로고    scopus 로고
    • Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization
    • Chakrabarti BK, Kong WP, Wu BY et al. Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization. J Virol 2002 76 : 5357 68.
    • (2002) J Virol , vol.76 , pp. 5357-68
    • Chakrabarti, B.K.1    Kong, W.P.2    Wu, B.Y.3
  • 63
    • 0036121261 scopus 로고    scopus 로고
    • Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins
    • Grundner C, Mirzabekov T, Sodroski J, Wyatt R. Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins. J Virol 2002 76 : 3511 21.
    • (2002) J Virol , vol.76 , pp. 3511-21
    • Grundner, C.1    Mirzabekov, T.2    Sodroski, J.3    Wyatt, R.4
  • 64
    • 14844300825 scopus 로고    scopus 로고
    • Virus-like particles as HIV-1 vaccines
    • Doan LX, Li M, Chen C, Yao Q. Virus-like particles as HIV-1 vaccines. Rev Med Virol 2004 15 : 75 88.
    • (2004) Rev Med Virol , vol.15 , pp. 75-88
    • Doan, L.X.1    Li, M.2    Chen, C.3    Yao, Q.4
  • 65
    • 0037015043 scopus 로고    scopus 로고
    • Crosslinked HIV-1 envelope-CD4 receptor complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques
    • Fouts T, Godfrey K, Bobb K et al. Crosslinked HIV-1 envelope-CD4 receptor complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques. Proc Natl Acad Sci U S A 2002 99 : 11842 7.
    • (2002) Proc Natl Acad Sci U S a , vol.99 , pp. 11842-7
    • Fouts, T.1    Godfrey, K.2    Bobb, K.3
  • 66
    • 0038414622 scopus 로고    scopus 로고
    • Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design
    • Pantophlet R, Wilson IA, Burton DR. Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design. J Virol 2003 77 : 5889 901.
    • (2003) J Virol , vol.77 , pp. 5889-901
    • Pantophlet, R.1    Wilson, I.A.2    Burton, D.R.3
  • 67
    • 12444337649 scopus 로고    scopus 로고
    • Improved design of an antigen with enhanced specificity for the broadly HIV-neutralizing antibody b12
    • Pantophlet R, Wilson IA, Burton DR. Improved design of an antigen with enhanced specificity for the broadly HIV-neutralizing antibody b12. Protein Eng Des Sel 2004 17 : 749 58.
    • (2004) Protein Eng des Sel , vol.17 , pp. 749-58
    • Pantophlet, R.1    Wilson, I.A.2    Burton, D.R.3
  • 68
    • 32444436232 scopus 로고    scopus 로고
    • Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody
    • Brunel FM, Zwick MB, Cardoso RM et al. Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody. J Virol 2006 80 : 1680 7.
    • (2006) J Virol , vol.80 , pp. 1680-7
    • Brunel, F.M.1    Zwick, M.B.2    Cardoso, R.M.3
  • 69
    • 33847101745 scopus 로고    scopus 로고
    • Structural definition of a conserved neutralization epitope on HIV-1 gp120
    • Zhou T, Xu L, Dey B et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature 2007 445 : 732 37.
    • (2007) Nature , vol.445 , pp. 732-37
    • Zhou, T.1    Xu, L.2    Dey, B.3
  • 70
    • 31144451337 scopus 로고    scopus 로고
    • Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants
    • Li Y, Svehla K, Mathy NL, Voss G, Mascola JR, Wyatt R. Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants. J Virol 2006 80 : 1414 26.
    • (2006) J Virol , vol.80 , pp. 1414-26
    • Li, Y.1    Svehla, K.2    Mathy, N.L.3    Voss, G.4    Mascola, J.R.5    Wyatt, R.6
  • 71
    • 0033923205 scopus 로고    scopus 로고
    • Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity
    • Tighe H, Takabayashi K, Schwartz D et al. Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity. Eur J Immunol 2000 30 : 1939 47.
    • (2000) Eur J Immunol , vol.30 , pp. 1939-47
    • Tighe, H.1    Takabayashi, K.2    Schwartz, D.3
  • 72
    • 27244443079 scopus 로고    scopus 로고
    • HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates
    • Wille-Reece U, Flynn BJ, Lore K et al. HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates. Proc Natl Acad Sci U S A 2005 102 : 15190 4.
    • (2005) Proc Natl Acad Sci U S a , vol.102 , pp. 15190-4
    • Wille-Reece, U.1    Flynn, B.J.2    Lore, K.3
  • 73
    • 20444430129 scopus 로고    scopus 로고
    • Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses
    • Wille-Reece U, Wu CY, Flynn BJ, Kedl RM, Seder RA. Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses. J Immunol 2005 174 : 7676 83.
    • (2005) J Immunol , vol.174 , pp. 7676-83
    • Wille-Reece, U.1    Wu, C.Y.2    Flynn, B.J.3    Kedl, R.M.4    Seder, R.A.5
  • 74
    • 0034598905 scopus 로고    scopus 로고
    • DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
    • Geijtenbeek TB, Kwon DS, Torensma R et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 2000 100 : 587 97.
    • (2000) Cell , vol.100 , pp. 587-97
    • Geijtenbeek, T.B.1    Kwon, D.S.2    Torensma, R.3
  • 75
    • 34347255209 scopus 로고    scopus 로고
    • Dendritic cell-mediated trans-enhancement of HIV-1 infectivity is independent of DC-SIGN
    • Boggiano C, Manel N, Littman DR. Dendritic cell-mediated trans-enhancement of HIV-1 infectivity is independent of DC-SIGN. J Virol 2006 82 : 2519 23.
    • (2006) J Virol , vol.82 , pp. 2519-23
    • Boggiano, C.1    Manel, N.2    Littman, D.R.3
  • 76
    • 0030790094 scopus 로고    scopus 로고
    • Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: Potential applications to microbicide development
    • Boyd MR, Gustafson KR, McMahon JB et al. Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. Antimicrob Agents Chemother 1997 41 : 1521 30.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1521-30
    • Boyd, M.R.1    Gustafson, K.R.2    McMahon, J.B.3
  • 77
    • 0032921247 scopus 로고    scopus 로고
    • Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120
    • Esser MT, Mori T, Mondor I et al. Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120. J Virol 1999 73 : 4360 71.
    • (1999) J Virol , vol.73 , pp. 4360-71
    • Esser, M.T.1    Mori, T.2    Mondor, I.3
  • 78
    • 0002948385 scopus 로고
    • Vaccine protection against simian immunodeficiency virus infection
    • Desrosiers RC, Wyand MS, Kodama T et al. Vaccine protection against simian immunodeficiency virus infection. Proc Natl Acad Sci U S A 1989 86 : 6353 7.
    • (1989) Proc Natl Acad Sci U S a , vol.86 , pp. 6353-7
    • Desrosiers, R.C.1    Wyand, M.S.2    Kodama, T.3
  • 79
    • 0024844908 scopus 로고
    • A formalin-inactivated whole SIV vaccine confers protection in macaques
    • Murphey-Corb M, Martin LN, Davison-Fairburn B et al. A formalin-inactivated whole SIV vaccine confers protection in macaques. Science 1989 246 : 1293 7.
    • (1989) Science , vol.246 , pp. 1293-7
    • Murphey-Corb, M.1    Martin, L.N.2    Davison-Fairburn, B.3
  • 80
    • 0029012807 scopus 로고
    • Antibody to adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1
    • Gomez MB, Hildreth JE. Antibody to adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1. J Virol 1995 69 : 4628 32.
    • (1995) J Virol , vol.69 , pp. 4628-32
    • Gomez, M.B.1    Hildreth, J.E.2
  • 81
    • 0030962180 scopus 로고    scopus 로고
    • Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization
    • Rizzuto CD, Sodroski JG. Contribution of virion ICAM-1 to human immunodeficiency virus infectivity and sensitivity to neutralization. J Virol 1997 71 : 4847 51.
    • (1997) J Virol , vol.71 , pp. 4847-51
    • Rizzuto, C.D.1    Sodroski, J.G.2
  • 82
    • 0023878973 scopus 로고
    • The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4
    • Landau NR, Warton M, Littman DR. The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4. Nature 1988 334 : 159 62.
    • (1988) Nature , vol.334 , pp. 159-62
    • Landau, N.R.1    Warton, M.2    Littman, D.R.3
  • 83
    • 0025807938 scopus 로고
    • Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralization by soluble CD4 possess high affinity for the CD4 receptor
    • Brighty DW, Rosenberg M, Chen IS, Ivey-Hoyle M. Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralization by soluble CD4 possess high affinity for the CD4 receptor. Proc Natl Acad Sci U S A 1991 88 : 7802 5.
    • (1991) Proc Natl Acad Sci U S a , vol.88 , pp. 7802-5
    • Brighty, D.W.1    Rosenberg, M.2    Chen, I.S.3    Ivey-Hoyle, M.4
  • 84
    • 0025794308 scopus 로고
    • Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4
    • Daar ES, Ho DD. Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4. Am J Med 1991 90 : 22S 6.
    • (1991) Am J Med , vol.90
    • Daar, E.S.1    Ho, D.D.2
  • 85
    • 0029062687 scopus 로고
    • Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates
    • Allaway GP, Davis-Bruno KL, Beaudry GA et al. Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates. AIDS Res Hum Retroviruses 1995 11 : 533 9.
    • (1995) AIDS Res Hum Retroviruses , vol.11 , pp. 533-9
    • Allaway, G.P.1    Davis-Bruno, K.L.2    Beaudry, G.A.3
  • 86
    • 0034984290 scopus 로고    scopus 로고
    • Structural flexibility and functional valence of CD4-IgG2 (PRO 542): Potential for cross-linking human immunodeficiency virus type 1 envelope spikes
    • Zhu P, Olson WC, Roux KH. Structural flexibility and functional valence of CD4-IgG2 (PRO 542): potential for cross-linking human immunodeficiency virus type 1 envelope spikes. J Virol 2001 75 : 6682 6.
    • (2001) J Virol , vol.75 , pp. 6682-6
    • Zhu, P.1    Olson, W.C.2    Roux, K.H.3
  • 87
    • 18644369147 scopus 로고    scopus 로고
    • The appealing story of HIV entry inhibitors: From discovery of biological mechanisms to drug development
    • Castagna A, Biswas P, Beretta A, Lazzarin A. The appealing story of HIV entry inhibitors: from discovery of biological mechanisms to drug development. Drugs 2005 65 : 879 904.
    • (2005) Drugs , vol.65 , pp. 879-904
    • Castagna, A.1    Biswas, P.2    Beretta, A.3    Lazzarin, A.4
  • 88
    • 0031900546 scopus 로고    scopus 로고
    • CD4-immunoglobulin G2 protects Hu-PBL-SCID mice against challenge by primary human immunodeficiency virus type 1 isolates
    • Gauduin MC, Allaway GP, Olson WC, Weir R, Maddon PJ, Koup RA. CD4-immunoglobulin G2 protects Hu-PBL-SCID mice against challenge by primary human immunodeficiency virus type 1 isolates. J Virol 1998 72 : 3475 8.
    • (1998) J Virol , vol.72 , pp. 3475-8
    • Gauduin, M.C.1    Allaway, G.P.2    Olson, W.C.3    Weir, R.4    Maddon, P.J.5    Koup, R.A.6
  • 89
    • 9144250171 scopus 로고    scopus 로고
    • Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO 542
    • Jacobson JM, Israel RJ, Lowy I et al. Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO 542. Antimicrob Agents Chemother 2004 48 : 423 9.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 423-9
    • Jacobson, J.M.1    Israel, R.J.2    Lowy, I.3
  • 90
    • 0025176060 scopus 로고
    • Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding
    • Healey D, Dianda L, Moore JP et al. Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding. J Exp Med 1990 172 : 1233 42.
    • (1990) J Exp Med , vol.172 , pp. 1233-42
    • Healey, D.1    Dianda, L.2    Moore, J.P.3
  • 91
    • 0026654557 scopus 로고
    • A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells
    • Moore JP, Sattentau QJ, Klasse PJ, Burkly LC. A monoclonal antibody to CD4 domain 2 blocks soluble CD4-induced conformational changes in the envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) and HIV-1 infection of CD4+ cells. J Virol 1992 66 : 4784 93.
    • (1992) J Virol , vol.66 , pp. 4784-93
    • Moore, J.P.1    Sattentau, Q.J.2    Klasse, P.J.3    Burkly, L.C.4
  • 93
    • 0029075622 scopus 로고
    • Synergistic inhibition of human immunodeficiency virus type 1 envelope glycoprotein-mediated cell fusion and infection by an antibody to CD4 domain 2 in combination with anti-gp120 antibodies
    • Burkly L, Mulrey N, Blumenthal R, Dimitrov DS. Synergistic inhibition of human immunodeficiency virus type 1 envelope glycoprotein-mediated cell fusion and infection by an antibody to CD4 domain 2 in combination with anti-gp120 antibodies. J Virol 1995 69 : 4267 73.
    • (1995) J Virol , vol.69 , pp. 4267-73
    • Burkly, L.1    Mulrey, N.2    Blumenthal, R.3    Dimitrov, D.S.4
  • 94
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
    • Liu R, Paxton WA, Choe S et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996 86 : 367 77.
    • (1996) Cell , vol.86 , pp. 367-77
    • Liu, R.1    Paxton, W.A.2    Choe, S.3
  • 96
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
    • Dean M, Carrington M, Winkler C et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 1996 273 : 1856 62.
    • (1996) Science , vol.273 , pp. 1856-62
    • Dean, M.1    Carrington, M.2    Winkler, C.3
  • 97
    • 16044373004 scopus 로고    scopus 로고
    • Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
    • Samson M, Libert F, Doranz BJ et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996 382 : 722 5.
    • (1996) Nature , vol.382 , pp. 722-5
    • Samson, M.1    Libert, F.2    Doranz, B.J.3
  • 98
    • 0029986131 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of a new human CC-chemokine receptor gene
    • Samson M, Labbe O, Mollereau C, Vassart G, Parmentier M. Molecular cloning and functional expression of a new human CC-chemokine receptor gene. Biochemistry 1996 35 : 3362 7.
    • (1996) Biochemistry , vol.35 , pp. 3362-7
    • Samson, M.1    Labbe, O.2    Mollereau, C.3    Vassart, G.4    Parmentier, M.5
  • 99
    • 0030587441 scopus 로고    scopus 로고
    • The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3
    • Samson M, Soularue P, Vassart G, Parmentier M. The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3. Genomics 1996 36 : 522 6.
    • (1996) Genomics , vol.36 , pp. 522-6
    • Samson, M.1    Soularue, P.2    Vassart, G.3    Parmentier, M.4
  • 100
    • 0032522661 scopus 로고    scopus 로고
    • Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor
    • Zhou Y, Kurihara T, Ryseck RP et al. Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J Immunol 1998 160 : 4018 25.
    • (1998) J Immunol , vol.160 , pp. 4018-25
    • Zhou, Y.1    Kurihara, T.2    Ryseck, R.P.3
  • 101
    • 0034653980 scopus 로고    scopus 로고
    • CCR5-reactive antibodies in seronegative partners of HIV-seropositive individuals down-modulate surface CCR5 in vivo and neutralize the infectivity of R5 strains of HIV-1 in vitro
    • Lopalco L, Barassi C, Pastori C et al. CCR5-reactive antibodies in seronegative partners of HIV-seropositive individuals down-modulate surface CCR5 in vivo and neutralize the infectivity of R5 strains of HIV-1 in vitro. J Immunol 2000 164 : 3426 33.
    • (2000) J Immunol , vol.164 , pp. 3426-33
    • Lopalco, L.1    Barassi, C.2    Pastori, C.3
  • 102
    • 0033972247 scopus 로고    scopus 로고
    • Anti-cell antibodies in exposed seronegative individuals with HIV type 1-neutralizing activity
    • Lopalco L, Pastori C, Cosma A et al. Anti-cell antibodies in exposed seronegative individuals with HIV type 1-neutralizing activity. AIDS Res Hum Retroviruses 2000 16 : 109 15.
    • (2000) AIDS Res Hum Retroviruses , vol.16 , pp. 109-15
    • Lopalco, L.1    Pastori, C.2    Cosma, A.3
  • 103
    • 33745077706 scopus 로고    scopus 로고
    • Long-lasting CCR5 internalization by antibodies in a subset of long-term nonprogressors: A possible protective effect against disease progression
    • Pastori C, Weiser B, Barassi C et al. Long-lasting CCR5 internalization by antibodies in a subset of long-term nonprogressors: a possible protective effect against disease progression. Blood 2006 107 : 4825 33.
    • (2006) Blood , vol.107 , pp. 4825-33
    • Pastori, C.1    Weiser, B.2    Barassi, C.3
  • 104
    • 3042780489 scopus 로고    scopus 로고
    • Co-receptor antagonists as HIV-1 entry inhibitors
    • Shaheen F, Collman RG. Co-receptor antagonists as HIV-1 entry inhibitors. Curr Opin Infect Dis 2004 17 : 7 16.
    • (2004) Curr Opin Infect Dis , vol.17 , pp. 7-16
    • Shaheen, F.1    Collman, R.G.2
  • 105
    • 0034625144 scopus 로고    scopus 로고
    • A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
    • Dragic T, Trkola A, Thompson DA et al. A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5. Proc Natl Acad Sci U S A 2000 97 : 5639 44.
    • (2000) Proc Natl Acad Sci U S a , vol.97 , pp. 5639-44
    • Dragic, T.1    Trkola, A.2    Thompson, D.A.3
  • 106
    • 33846574670 scopus 로고    scopus 로고
    • Isolation and characterization of human immunodeficiency virus type 1 resistant to the small-molecule CCR5 antagonist TAK-652
    • Baba M, Miyake H, Wang X, Okamoto M, Takashima K. Isolation and characterization of human immunodeficiency virus type 1 resistant to the small-molecule CCR5 antagonist TAK-652. Antimicrob Agents Chemother 2007 51 : 707 15.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 707-15
    • Baba, M.1    Miyake, H.2    Wang, X.3    Okamoto, M.4    Takashima, K.5
  • 107
    • 20644453529 scopus 로고    scopus 로고
    • Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D)
    • Marozsan AJ, Kuhmann SE, Morgan T et al. Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D). Virology 2005 338 : 182 99.
    • (2005) Virology , vol.338 , pp. 182-99
    • Marozsan, A.J.1    Kuhmann, S.E.2    Morgan, T.3
  • 108
    • 0037039380 scopus 로고    scopus 로고
    • HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
    • Trkola A, Kuhmann SE, Strizki JM et al. HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use. Proc Natl Acad Sci U S A 2002 99 : 395 400.
    • (2002) Proc Natl Acad Sci U S a , vol.99 , pp. 395-400
    • Trkola, A.1    Kuhmann, S.E.2    Strizki, J.M.3
  • 109
    • 0033941573 scopus 로고    scopus 로고
    • Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1
    • Kuhmann SE, Platt EJ, Kozak SL, Kabat D. Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1. J Virol 2000 74 : 7005 15.
    • (2000) J Virol , vol.74 , pp. 7005-15
    • Kuhmann, S.E.1    Platt, E.J.2    Kozak, S.L.3    Kabat, D.4
  • 110
    • 0033515588 scopus 로고    scopus 로고
    • Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function
    • Lee B, Sharron M, Blanpain C et al. Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J Biol Chem 1999 274 : 9617 26.
    • (1999) J Biol Chem , vol.274 , pp. 9617-26
    • Lee, B.1    Sharron, M.2    Blanpain, C.3
  • 111
    • 16144365650 scopus 로고    scopus 로고
    • CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
    • Wu L, Gerard NP, Wyatt R et al. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature 1996 384 : 179 83.
    • (1996) Nature , vol.384 , pp. 179-83
    • Wu, L.1    Gerard, N.P.2    Wyatt, R.3
  • 112
    • 0031024664 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent
    • McKnight A, Wilkinson D, Simmons G et al. Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent. J Virol 1997 71 : 1692 6.
    • (1997) J Virol , vol.71 , pp. 1692-6
    • McKnight, A.1    Wilkinson, D.2    Simmons, G.3
  • 113
    • 0030946088 scopus 로고    scopus 로고
    • A monoclonal antibody (12G5) directed against CXCR-4 inhibits infection with the dual-tropic human immunodeficiency virus type 1 isolate HIV-1(89.6) but not the T-tropic isolate HIV-1(HxB)
    • Strizki JM, Turner JD, Collman RG, Hoxie J, Gonzalez-Scarano F. A monoclonal antibody (12G5) directed against CXCR-4 inhibits infection with the dual-tropic human immunodeficiency virus type 1 isolate HIV-1(89.6) but not the T-tropic isolate HIV-1(HxB). J Virol 1997 71 : 5678 83.
    • (1997) J Virol , vol.71 , pp. 5678-83
    • Strizki, J.M.1    Turner, J.D.2    Collman, R.G.3    Hoxie, J.4    Gonzalez-Scarano, F.5
  • 114
    • 0036521783 scopus 로고    scopus 로고
    • Trastuzumab: Hopes and realities
    • Leyland-Jones B. Trastuzumab: hopes and realities. Lancet Oncol 2002 3 : 137 44.
    • (2002) Lancet Oncol , vol.3 , pp. 137-44
    • Leyland-Jones, B.1
  • 115
    • 4344684305 scopus 로고    scopus 로고
    • Induction of immune responses and break of tolerance by DNA against the HIV-1 co-receptor CCR5 but no protections from SIV SM challenge
    • Zuber B, Hinkula J, Levi M, Lundholm P, Nilsson C, Wahren B. Induction of immune responses and break of tolerance by DNA against the HIV-1 co-receptor CCR5 but no protections from SIV SM challenge. Virology 2000 633 : 1 10.
    • (2000) Virology , vol.633 , pp. 1-10
    • Zuber, B.1    Hinkula, J.2    Levi, M.3    Lundholm, P.4    Nilsson, C.5    Wahren, B.6
  • 116
    • 1842431907 scopus 로고    scopus 로고
    • Induction of autoantibodies to CCR5 in macaques and subsequent effects upon challenge with an R5-tropic simian/human immunodeficiency virus
    • Chackerian B, Briglio L, Albert PS, Lowy DR, Schiller JT. Induction of autoantibodies to CCR5 in macaques and subsequent effects upon challenge with an R5-tropic simian/human immunodeficiency virus. J Virol 2004 78 : 4037 47.
    • (2004) J Virol , vol.78 , pp. 4037-47
    • Chackerian, B.1    Briglio, L.2    Albert, P.S.3    Lowy, D.R.4    Schiller, J.T.5
  • 117
    • 18744371874 scopus 로고    scopus 로고
    • Identification of a linear peptide recognized by monoclonal antibody 2D7 capable of generating CCR5-specific antibodies with human immunodeficiency virus-neutralizing activity
    • Khurana S, Kennedy M, King LR, Golding H. Identification of a linear peptide recognized by monoclonal antibody 2D7 capable of generating CCR5-specific antibodies with human immunodeficiency virus-neutralizing activity. J Virol 2005 79 : 6791 800.
    • (2005) J Virol , vol.79 , pp. 6791-800
    • Khurana, S.1    Kennedy, M.2    King, L.R.3    Golding, H.4
  • 118
    • 0034047889 scopus 로고    scopus 로고
    • Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5
    • Mirzabekov T, Kontos H, Farzan M, Marasco W, Sodroski J. Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5. Nat Biotechnol 2000 18 : 649 54.
    • (2000) Nat Biotechnol , vol.18 , pp. 649-54
    • Mirzabekov, T.1    Kontos, H.2    Farzan, M.3    Marasco, W.4    Sodroski, J.5
  • 119
    • 33646854560 scopus 로고    scopus 로고
    • A biosensor-based approach toward purification and crystallization of G protein-coupled receptors
    • Navratilova I, Pancera M, Wyatt RT, Myszka DG. A biosensor-based approach toward purification and crystallization of G protein-coupled receptors. Anal Biochem 2006 353 : 278 83.
    • (2006) Anal Biochem , vol.353 , pp. 278-83
    • Navratilova, I.1    Pancera, M.2    Wyatt, R.T.3    Myszka, D.G.4
  • 120
    • 15444376596 scopus 로고    scopus 로고
    • Solubilization, stabilization, and purification of chemokine receptors using biosensor technology
    • Navratilova I, Sodroski J, Myszka DG. Solubilization, stabilization, and purification of chemokine receptors using biosensor technology. Anal Biochem 2005 339 : 271 81.
    • (2005) Anal Biochem , vol.339 , pp. 271-81
    • Navratilova, I.1    Sodroski, J.2    Myszka, D.G.3
  • 121
    • 33947406436 scopus 로고    scopus 로고
    • Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities
    • Ji C, Brandt M, Dioszegi M et al. Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities. Antiviral Res 2006 74 : 125 37.
    • (2006) Antiviral Res , vol.74 , pp. 125-37
    • Ji, C.1    Brandt, M.2    Dioszegi, M.3
  • 122
    • 0034680852 scopus 로고    scopus 로고
    • Generation and characterization of a recombinant human CCR5-specific antibody. a phage display approach for rabbit antibody humanization
    • Steinberger P, Sutton JK, Rader C, Elia M, Barbas CF III. Generation and characterization of a recombinant human CCR5-specific antibody. A phage display approach for rabbit antibody humanization. J Biol Chem 2000 275 : 36073 8.
    • (2000) J Biol Chem , vol.275 , pp. 36073-8
    • Steinberger, P.1    Sutton, J.K.2    Rader, C.3    Elia, M.4    Barbas Iii., C.F.5
  • 123
    • 4744371116 scopus 로고    scopus 로고
    • Selection of active ScFv to G-protein-coupled receptor CCR5 using surface antigen-mimicking peptides
    • Zhang Y, Pool C, Sadler K et al. Selection of active ScFv to G-protein-coupled receptor CCR5 using surface antigen-mimicking peptides. Biochemistry 2004 43 : 12575 84.
    • (2004) Biochemistry , vol.43 , pp. 12575-84
    • Zhang, Y.1    Pool, C.2    Sadler, K.3
  • 124
  • 125
    • 0031812844 scopus 로고    scopus 로고
    • The acquisition of host-encoded proteins by nascent HIV-1
    • Tremblay MJ, Fortin JF, Cantin R. The acquisition of host-encoded proteins by nascent HIV-1. Immunol Today 1998 19 : 346 51.
    • (1998) Immunol Today , vol.19 , pp. 346-51
    • Tremblay, M.J.1    Fortin, J.F.2    Cantin, R.3
  • 126
    • 5644247983 scopus 로고    scopus 로고
    • Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
    • Lederman MM, Veazey RS, Offord R et al. Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5. Science 2004 306 : 485 7.
    • (2004) Science , vol.306 , pp. 485-7
    • Lederman, M.M.1    Veazey, R.S.2    Offord, R.3
  • 127
    • 27744571425 scopus 로고    scopus 로고
    • Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion
    • Veazey RS, Klasse PJ, Schader SM et al. Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion. Nature 2005 438 : 99 102.
    • (2005) Nature , vol.438 , pp. 99-102
    • Veazey, R.S.1    Klasse, P.J.2    Schader, S.M.3
  • 129
    • 0020556228 scopus 로고
    • Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor
    • Lando Z, Sarin P, Megson M et al. Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor. Nature 1983 305 : 733 6.
    • (1983) Nature , vol.305 , pp. 733-6
    • Lando, Z.1    Sarin, P.2    Megson, M.3
  • 130
    • 0025702622 scopus 로고
    • Efficient incorporation of human CD4 protein into avian leukosis virus particles
    • Young JA, Bates P, Willert K, Varmus HE. Efficient incorporation of human CD4 protein into avian leukosis virus particles. Science 1990 250 : 1421 3.
    • (1990) Science , vol.250 , pp. 1421-3
    • Young, J.A.1    Bates, P.2    Willert, K.3    Varmus, H.E.4
  • 131
    • 0025648199 scopus 로고
    • Preliminary report: Protection of cynomolgus macaques against simian immunodeficiency virus by fixed infected-cell vaccine
    • Stott EJ, Chan WL, Mills KH et al. Preliminary report: protection of cynomolgus macaques against simian immunodeficiency virus by fixed infected-cell vaccine. Lancet 1990 336 : 1538 41.
    • (1990) Lancet , vol.336 , pp. 1538-41
    • Stott, E.J.1    Chan, W.L.2    Mills, K.H.3
  • 132
    • 0025902165 scopus 로고
    • Anti-cell antibody in macaques
    • Stott EJ. Anti-cell antibody in macaques. Nature 1991 353 : 393.
    • (1991) Nature , vol.353 , pp. 393
    • Stott, E.J.1
  • 133
    • 0027049212 scopus 로고
    • Cellular proteins bound to immunodeficiency viruses: Implications for pathogenesis and vaccines
    • Arthur LO, Bess JW Jr., Sowder RC II. et al. Cellular proteins bound to immunodeficiency viruses: implications for pathogenesis and vaccines. Science 1992 258 : 1935 8.
    • (1992) Science , vol.258 , pp. 1935-8
    • Arthur, L.O.1    Bess Jr., J.W.2    Sowder, I.I.R.C.3
  • 134
    • 0034973233 scopus 로고    scopus 로고
    • Differential incorporation of CD45, CD80 (B7-1), CD86 (B7-2), and major histocompatibility complex class I and II molecules into human immunodeficiency virus type 1 virions and microvesicles: Implications for viral pathogenesis and immune regulation
    • Esser MT, Graham DR, Coren LV et al. Differential incorporation of CD45, CD80 (B7-1), CD86 (B7-2), and major histocompatibility complex class I and II molecules into human immunodeficiency virus type 1 virions and microvesicles: implications for viral pathogenesis and immune regulation. J Virol 2001 75 : 6173 82.
    • (2001) J Virol , vol.75 , pp. 6173-82
    • Esser, M.T.1    Graham, D.R.2    Coren, L.V.3
  • 135
    • 0029853890 scopus 로고    scopus 로고
    • Acquisition of host cell-surface-derived molecules by HIV-1
    • Frank I, Stoiber H, Godar S et al. Acquisition of host cell-surface-derived molecules by HIV-1. AIDS 1996 10 : 1611 20.
    • (1996) AIDS , vol.10 , pp. 1611-20
    • Frank, I.1    Stoiber, H.2    Godar, S.3
  • 136
    • 0027332763 scopus 로고
    • Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV
    • Orentas RJ, Hildreth JE. Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV. AIDS Res Hum Retroviruses 1993 9 : 1157 65.
    • (1993) AIDS Res Hum Retroviruses , vol.9 , pp. 1157-65
    • Orentas, R.J.1    Hildreth, J.E.2
  • 137
    • 0026731901 scopus 로고
    • Protection in simian immunodeficiency virus-vaccinated monkeys correlates with anti-HLA class I antibody response
    • Chan WL, Rodgers A, Hancock RD et al. Protection in simian immunodeficiency virus-vaccinated monkeys correlates with anti-HLA class I antibody response. J Exp Med 1992 176 : 1203 7.
    • (1992) J Exp Med , vol.176 , pp. 1203-7
    • Chan, W.L.1    Rodgers, A.2    Hancock, R.D.3
  • 138
    • 0028987483 scopus 로고
    • Macaques immunized with HLA-DR are protected from challenge with simian immunodeficiency virus
    • Arthur LO, Bess JW Jr., Urban RG et al. Macaques immunized with HLA-DR are protected from challenge with simian immunodeficiency virus. J Virol 1995 69 : 3117 24.
    • (1995) J Virol , vol.69 , pp. 3117-24
    • Arthur, L.O.1    Bess Jr., J.W.2    Urban, R.G.3
  • 140
    • 33846644063 scopus 로고    scopus 로고
    • Specificity of anti-human leukocyte antigen antibody responses after immunization with Remune, an inactivated HIV-1 vaccine
    • Page M, Ojugo A, Imami N, Hardy G, Gotch F, Almond N. Specificity of anti-human leukocyte antigen antibody responses after immunization with Remune, an inactivated HIV-1 vaccine. AIDS 2007 21 : 375 7.
    • (2007) AIDS , vol.21 , pp. 375-7
    • Page, M.1    Ojugo, A.2    Imami, N.3    Hardy, G.4    Gotch, F.5    Almond, N.6
  • 141
    • 33745961328 scopus 로고    scopus 로고
    • Innate and adaptive mucosal immunity in protection against HIV infection
    • Bergmeier LA, Lehner T Innate and adaptive mucosal immunity in protection against HIV infection. Adv Dent Res 2006 19 : 21 8.
    • (2006) Adv Dent Res , vol.19 , pp. 21-8
    • Bergmeier, L.A.1    Lehner, T.2
  • 142
    • 17344369061 scopus 로고    scopus 로고
    • Mother-child class I HLA concordance increases perinatal human immunodeficiency virus type 1 transmission
    • MacDonald KS, Embree J, Njenga S et al. Mother-child class I HLA concordance increases perinatal human immunodeficiency virus type 1 transmission. J Infect Dis 1998 177 : 551 6.
    • (1998) J Infect Dis , vol.177 , pp. 551-6
    • MacDonald, K.S.1    Embree, J.2    Njenga, S.3
  • 143
    • 0037423819 scopus 로고    scopus 로고
    • Recent observations on HIV type-1 infection in the genital tract of men and women
    • Coombs RW, Reichelderfer PS, Landay AL. Recent observations on HIV type-1 infection in the genital tract of men and women. AIDS 2003 17 : 455 80.
    • (2003) AIDS , vol.17 , pp. 455-80
    • Coombs, R.W.1    Reichelderfer, P.S.2    Landay, A.L.3
  • 144
    • 0034662387 scopus 로고    scopus 로고
    • Anti-major histocompatibility complex antibody responses in macaques via intradermal DNA immunizations
    • Dela Cruz CS, MacDonald KS, Barber BH. Anti-major histocompatibility complex antibody responses in macaques via intradermal DNA immunizations. Vaccine 2000 18 : 3152 65.
    • (2000) Vaccine , vol.18 , pp. 3152-65
    • Dela Cruz, C.S.1    MacDonald, K.S.2    Barber, B.H.3
  • 145
    • 0036694204 scopus 로고    scopus 로고
    • Whole inactivated SIV virion vaccines with functional envelope glycoproteins: Safety, immunogenicity, and activity against intrarectal challenge
    • Lifson JD, Piatak M Jr., Rossio JL et al. Whole inactivated SIV virion vaccines with functional envelope glycoproteins: safety, immunogenicity, and activity against intrarectal challenge. J Med Primatol 2002 31 : 205 16.
    • (2002) J Med Primatol , vol.31 , pp. 205-16
    • Lifson, J.D.1    Piatak Jr., M.2    Rossio, J.L.3
  • 146
    • 0029743737 scopus 로고    scopus 로고
    • Phenotypic analysis of antigen-specific T lymphocytes
    • Altman JD, Moss PA, Goulder PJ et al. Phenotypic analysis of antigen-specific T lymphocytes. Science 1996 274 : 94 6.
    • (1996) Science , vol.274 , pp. 94-6
    • Altman, J.D.1    Moss, P.A.2    Goulder, P.J.3
  • 147
    • 23744465597 scopus 로고    scopus 로고
    • Measuring Ag-specific immune responses: Understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer
    • Kern F, LiPira G, Gratama JW, Manca F, Roederer M. Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer. Trends Immunol 2005 26 : 477 84.
    • (2005) Trends Immunol , vol.26 , pp. 477-84
    • Kern, F.1    Lipira, G.2    Gratama, J.W.3    Manca, F.4    Roederer, M.5
  • 148
    • 0036222617 scopus 로고    scopus 로고
    • Class II peptide multimers: Promise for type 1A diabetes
    • Eisenbarth GS, Nepom GT. Class II peptide multimers: promise for type 1A diabetes Nat Immunol 2002 3 : 344 5.
    • (2002) Nat Immunol , vol.3 , pp. 344-5
    • Eisenbarth, G.S.1    Nepom, G.T.2
  • 149
    • 0033381821 scopus 로고    scopus 로고
    • The arrival of HLA class II tetramers
    • McMichael AJ, Kelleher A. The arrival of HLA class II tetramers. J Clin Invest 1999 104 : 1669 70.
    • (1999) J Clin Invest , vol.104 , pp. 1669-70
    • McMichael, A.J.1    Kelleher, A.2
  • 150
    • 29144488412 scopus 로고    scopus 로고
    • Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen- or tumour-derived synthetic peptides
    • Moro M, Cecconi V, Martinoli C et al. Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen- or tumour-derived synthetic peptides. BMC Immunol 2005 6 : 24.
    • (2005) BMC Immunol , vol.6 , pp. 24
    • Moro, M.1    Cecconi, V.2    Martinoli, C.3
  • 152
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodeficiency virus type 1 infection
    • Wei X, Ghosh SK, Taylor ME et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature 1995 373 : 117 22.
    • (1995) Nature , vol.373 , pp. 117-22
    • Wei, X.1    Ghosh, S.K.2    Taylor, M.E.3
  • 153
    • 0036147255 scopus 로고    scopus 로고
    • Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo
    • Bounou S, Leclerc JE, Tremblay MJ. Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo. J Virol 2002 76 : 1004 14.
    • (2002) J Virol , vol.76 , pp. 1004-14
    • Bounou, S.1    Leclerc, J.E.2    Tremblay, M.J.3
  • 154
    • 0030894767 scopus 로고    scopus 로고
    • Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity
    • Fortin JF, Cantin R, Lamontagne G, Tremblay M. Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity. J Virol 1997 71 : 3588 96.
    • (1997) J Virol , vol.71 , pp. 3588-96
    • Fortin, J.F.1    Cantin, R.2    Lamontagne, G.3    Tremblay, M.4


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