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Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 10, 2002, Pages 6913-6918

Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes

(13) Moulard, Maxime a,e Phogat, Sanjay K b Shu, Yuuei b Labrijn, Aran F a Xiao, Dong b Binley, James M a Zhang, Mei Yun b Sidorov, Igor A b Broder, Christopher C c Robinson, James d Parren, Paul W H I a,f Burton, Dennis R a Dimitrov, Dimiter S b

a SCRIPPS RESEARCH INSTITUTE (United States)

b NATIONAL CANCER INSTITUTE (United States)

c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES (United States)

d TULANE UNIVERSITY SCHOOL OF MEDICINE (United States)

e Biocytex (France)

f GENMAB (Netherlands)

Author keywords

AIDS; Antibody; Inhibitors; Vaccines

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CROSS REACTING ANTIBODY; EPITOPE; EPITOPE X5; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VACCINE; VIRUS ENVELOPE PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL CELL; ANTIBODY TITER; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; CELL FUSION; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MONONUCLEAR CELL; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIGENS, CD4; BINDING, COMPETITIVE; CELL FUSION; CELL LINE; CELL MEMBRANE; CROSS REACTIONS; GENE PRODUCTS, ENV; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; NEUTRALIZATION TESTS; PEPTIDE LIBRARY; RECEPTORS, CCR5;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037076265 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.102562599 Document Type: Article

Times cited : (204)

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