-
1
-
-
0029664297
-
Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
-
Raz, E., Tighe, H., Sato, Y., Corr, M., Dudler, J. A., Roman, M., Swain, S. L., Spiegelberg, H. L. and Carson, D. A., Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc. Natl. Acad. Sci. USA 1996. 93: 5141-5145.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5141-5145
-
-
Raz, E.1
Tighe, H.2
Sato, Y.3
Corr, M.4
Dudler, J.A.5
Roman, M.6
Swain, S.L.7
Spiegelberg, H.L.8
Carson, D.A.9
-
2
-
-
0023671911
-
Isotype regulation by helper T cells and lymphokines
-
Coffman, R. L. and Mosmann, T. R., Isotype regulation by helper T cells and lymphokines. Monogr. Allergy 1988. 24: 96-103.
-
(1988)
Monogr. Allergy
, vol.24
, pp. 96-103
-
-
Coffman, R.L.1
Mosmann, T.R.2
-
3
-
-
0030973578
-
DNA vaccines
-
Donnelly, J. J., Ulmer, J. B., Shiver, J. W. and Liu, M. A., DNA vaccines. Annu. Rev. Immunol. 1997. 15: 617-648.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 617-648
-
-
Donnelly, J.J.1
Ulmer, J.B.2
Shiver, J.W.3
Liu, M.A.4
-
4
-
-
0028060149
-
Intradermal gene immunization: The possible role of DNA uptake in the induction of cellular immunity to viruses
-
Raz, E., Carson, D. A., Parker, S. E. et al., Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses. Proc. Natl. Acad. Sci. USA 1994. 91: 9519-9523.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9519-9523
-
-
Raz, E.1
Carson, D.A.2
Parker, S.E.3
-
5
-
-
0029617572
-
Induction of protective immunity against herpes simplex virus with DNA encoding the immediate early protein ICP 27
-
Manickan, E., Yu, Z., Rouse, R. J., Wire, W. S. and Rouse, B. T., Induction of protective immunity against herpes simplex virus with DNA encoding the immediate early protein ICP 27. Viral Immunol. 1995. 8: 53-61.
-
(1995)
Viral Immunol.
, vol.8
, pp. 53-61
-
-
Manickan, E.1
Yu, Z.2
Rouse, R.J.3
Wire, W.S.4
Rouse, B.T.5
-
6
-
-
0027411456
-
Heterologous protection against influenza by injection of DNA encoding a viral protein
-
Ulmer, J. B., Donnelly, J. J., Parker, S. E. et al., Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993. 259: 1745-1749.
-
(1993)
Science
, vol.259
, pp. 1745-1749
-
-
Ulmer, J.B.1
Donnelly, J.J.2
Parker, S.E.3
-
7
-
-
0030764558
-
Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants
-
Roman, M., Martin-Orozco, E., Goodman, J. S., Nguyen, M. D., Sato, Y., Ronaghy, A., Kornbluth, R. S., Richman, D. D., Carson, D. A. and Raz, E., Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nat. Med. 1997. 3: 849-854.
-
(1997)
Nat. Med.
, vol.3
, pp. 849-854
-
-
Roman, M.1
Martin-Orozco, E.2
Goodman, J.S.3
Nguyen, M.D.4
Sato, Y.5
Ronaghy, A.6
Kornbluth, R.S.7
Richman, D.D.8
Carson, D.A.9
Raz, E.10
-
8
-
-
8944253295
-
Immunostimulatory DNA sequences necessary for effective intradermal gene immunization
-
Sato, Y., Roman, M., Tighe, H., Lee, D., Corr, M., Nguyen, M. D., Silverman, G. J., Lotz, M., Carson, D. A. and Raz, E., Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 1996. 273: 352-354.
-
(1996)
Science
, vol.273
, pp. 352-354
-
-
Sato, Y.1
Roman, M.2
Tighe, H.3
Lee, D.4
Corr, M.5
Nguyen, M.D.6
Silverman, G.J.7
Lotz, M.8
Carson, D.A.9
Raz, E.10
-
9
-
-
0031569601
-
Contribution of CpG motifs to the immunogenicity of DNA vaccines
-
Klinman, D. M., Yamshchikov, G. and Ishigatsubo, Y., Contribution of CpG motifs to the immunogenicity of DNA vaccines. J. Immunol. 1997. 158: 3635-3639.
-
(1997)
J. Immunol.
, vol.158
, pp. 3635-3639
-
-
Klinman, D.M.1
Yamshchikov, G.2
Ishigatsubo, Y.3
-
10
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird, A. P., CpG-rich islands and the function of DNA methylation. Nature 1986. 321: 209-213.
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
11
-
-
0029984358
-
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
-
Klinman, D. M., Yi, A. K., Beaucage, S. L., Conover, J. and Krieg, A. M., CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma. Proc. Natl. Acad. Sci. USA 1996. 93: 2879-2883.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2879-2883
-
-
Klinman, D.M.1
Yi, A.K.2
Beaucage, S.L.3
Conover, J.4
Krieg, A.M.5
-
12
-
-
0030028722
-
Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha
-
Halpern, M. D., Kurlander, J. J. and Pisetsky, D. S., Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha. Cell. Immunol. 1996. 167: 72-78.
-
(1996)
Cell. Immunol.
, vol.167
, pp. 72-78
-
-
Halpern, M.D.1
Kurlander, J.J.2
Pisetsky, D.S.3
-
13
-
-
0029934754
-
Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides
-
Cowdery, J. S., Chace, J. H., Yi, A. K. and Krieg, A. M., Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides. J. Immunol. 1996. 156: 4570-4575.
-
(1996)
J. Immunol.
, vol.156
, pp. 4570-4575
-
-
Cowdery, J.S.1
Chace, J.H.2
Yi, A.K.3
Krieg, A.M.4
-
14
-
-
0026625208
-
Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN and augment IFN-mediated natural killer activity
-
Yamamoto, S., Yamamoto, T., Kataoka, T., Kuramoto, E., Yano, O. and Tokunaga, T., Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN and augment IFN-mediated natural killer activity. J. Immunol. 1992. 148: 4072-4076.
-
(1992)
J. Immunol.
, vol.148
, pp. 4072-4076
-
-
Yamamoto, S.1
Yamamoto, T.2
Kataoka, T.3
Kuramoto, E.4
Yano, O.5
Tokunaga, T.6
-
16
-
-
0030586560
-
A direct role for IFN-gamma in regulation of Th1 cell development
-
Bradley, L. M., Dalton, D. K. and Croft, M., A direct role for IFN-gamma in regulation of Th1 cell development. J. Immunol. 1996. 157: 1350-1358.
-
(1996)
J. Immunol.
, vol.157
, pp. 1350-1358
-
-
Bradley, L.M.1
Dalton, D.K.2
Croft, M.3
-
17
-
-
0028845730
-
Cloning of a new cytokine that induces IFN-gamma production by T cells
-
Okamura, H., Tsutsi, H., Komatsu, T. et al., Cloning of a new cytokine that induces IFN-gamma production by T cells. Nature 1995. 378: 88-91.
-
(1995)
Nature
, vol.378
, pp. 88-91
-
-
Okamura, H.1
Tsutsi, H.2
Komatsu, T.3
-
18
-
-
0028970060
-
Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
-
Trinchieri, G., Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 1995. 13: 251-276.
-
(1995)
Annu. Rev. Immunol.
, vol.13
, pp. 251-276
-
-
Trinchieri, G.1
-
19
-
-
0028918544
-
Interferon beta, a cofactor in the interferon gamma production induced by gram-negative bacteria in mice
-
Yaegashi, Y., Nielsen, P., Sing, A., Galanos, C. and Freudenberg, M. A., Interferon beta, a cofactor in the interferon gamma production induced by gram-negative bacteria in mice. J. Exp. Med. 1995. 181: 953-960.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 953-960
-
-
Yaegashi, Y.1
Nielsen, P.2
Sing, A.3
Galanos, C.4
Freudenberg, M.A.5
-
20
-
-
0032531036
-
Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: A role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA
-
Jakob, T., Walker, P. S., Krieg, A. M., Udey, M. C. and Vogel, J. C., Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA. J. Immunol. 1998. 161: 3042-3049.
-
(1998)
J. Immunol.
, vol.161
, pp. 3042-3049
-
-
Jakob, T.1
Walker, P.S.2
Krieg, A.M.3
Udey, M.C.4
Vogel, J.C.5
-
21
-
-
0032775793
-
Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences
-
Martin-Orozco, E., Kobayashi, H., Van Uden, J., Nguyan, M.-D., Kornbluth, R. S. and Raz, E., Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences. Int. Immunol. 1999. 11: 1111-1118.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1111-1118
-
-
Martin-Orozco, E.1
Kobayashi, H.2
Van Uden, J.3
Nguyan, M.-D.4
Kornbluth, R.S.5
Raz, E.6
-
22
-
-
0031964257
-
DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
-
Davis, H. L., Weeranta, R., Waldschmidt, T. J., Tygrett, L., Schorr, J. and Krieg, A. M., DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J. Immunol. 1998. 160: 870-876.
-
(1998)
J. Immunol.
, vol.160
, pp. 870-876
-
-
Davis, H.L.1
Weeranta, R.2
Waldschmidt, T.J.3
Tygrett, L.4
Schorr, J.5
Krieg, A.M.6
-
23
-
-
0030613651
-
CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity
-
Chu, R. S., Targoni, O. S., Krieg, A. M., Lehmann, P. V. and Harding, C. V., CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J. Exp. Med. 1997. 186: 1623-1631.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1623-1631
-
-
Chu, R.S.1
Targoni, O.S.2
Krieg, A.M.3
Lehmann, P.V.4
Harding, C.V.5
-
24
-
-
0030850462
-
CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: A new class of vaccine adjuvants
-
Lipford, G. B., Bauer, M., Blank, C., Reiter, R., Wagner, H. and Heeg, K., CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants. Eur. J. Immunol. 1997. 27: 2340-2344.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 2340-2344
-
-
Lipford, G.B.1
Bauer, M.2
Blank, C.3
Reiter, R.4
Wagner, H.5
Heeg, K.6
-
25
-
-
0029091006
-
Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo
-
Bohm, W., Schirmbeck, R., Elbe, A., Melber, K., Diminky, D., Kraal, G., van Rooijen, N., Barenholz, Y. and Reimann, J., Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo. J. Immunol. 1995. 155: 3313-3321.
-
(1995)
J. Immunol.
, vol.155
, pp. 3313-3321
-
-
Bohm, W.1
Schirmbeck, R.2
Elbe, A.3
Melber, K.4
Diminky, D.5
Kraal, G.6
Van Rooijen, N.7
Barenholz, Y.8
Reimann, J.9
-
26
-
-
0028910938
-
A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules
-
Kovacsovics-Bankowski, M. and Rock, K. L., A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science 1995. 267: 243-246.
-
(1995)
Science
, vol.267
, pp. 243-246
-
-
Kovacsovics-Bankowski, M.1
Rock, K.L.2
-
27
-
-
0028821994
-
Sensitization of MHC class I-restricted T cells to exogenous proteins: Evidence for an alternative class I-restricted antigen presentation pathway
-
Martinez-Kinader, B., Lipford, G. B., Wagner, H. and Heeg, K., Sensitization of MHC class I-restricted T cells to exogenous proteins: evidence for an alternative class I-restricted antigen presentation pathway. Immunology 1995. 86: 287-295.
-
(1995)
Immunology
, vol.86
, pp. 287-295
-
-
Martinez-Kinader, B.1
Lipford, G.B.2
Wagner, H.3
Heeg, K.4
-
28
-
-
0029149603
-
Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis
-
Reis e Sousa, C. and Germain, R. N., Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis. J. Exp. Med. 1995. 182: 841-851.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 841-851
-
-
Reis E Sousa, C.1
Germain, R.N.2
-
29
-
-
0034116281
-
Immunostimulatory sequence oligodeoxynucleotides: A novel mucosal adjuvant
-
Horner, A. A. and Raz, E., Immunostimulatory sequence oligodeoxynucleotides: a novel mucosal adjuvant. Clin. Immunol. 2000. 95: S19-S29.
-
(2000)
Clin. Immunol.
, vol.95
-
-
Horner, A.A.1
Raz, E.2
-
30
-
-
0017126775
-
Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay
-
Bevan, M. J., Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 1976. 143: 1283-1288.
-
(1976)
J. Exp. Med.
, vol.143
, pp. 1283-1288
-
-
Bevan, M.J.1
-
31
-
-
0030763047
-
Presentation of exogenous protein antigen on major histocompatibility complex class I molecules by dendritic cells: Pathway of presentation and regulation by cytokines
-
Brossart, P. and Bevan, M. J., Presentation of exogenous protein antigen on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines. Blood 1997. 90: 1594-1599.
-
(1997)
Blood
, vol.90
, pp. 1594-1599
-
-
Brossart, P.1
Bevan, M.J.2
-
32
-
-
0030028770
-
Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo
-
Paglia, P., Chiodoni, C., Rodolfo, M. and Colombo, M. P., Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo. J. Exp. Med. 1996. 183: 317-322.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 317-322
-
-
Paglia, P.1
Chiodoni, C.2
Rodolfo, M.3
Colombo, M.P.4
-
33
-
-
0031867535
-
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
-
Sparwasser, T., Koch, E. S., Vabulas, R. M., Heeg, K., Lipford, G. B., Ellwart, J. W. and Wagner, H., Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol. 1998. 28: 2045-2054.
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2045-2054
-
-
Sparwasser, T.1
Koch, E.S.2
Vabulas, R.M.3
Heeg, K.4
Lipford, G.B.5
Ellwart, J.W.6
Wagner, H.7
-
34
-
-
0028096083
-
Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-gamma in vivo
-
Gately, M. K., Warrier, R. R., Honasoge, S., Carvajal, D. M., Faherty, D. A., Connaughton, S. E., Anderson, T. D., Sarmiento, U., Hubbard, B. R. and Murphy, M., Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-gamma in vivo. Int. Immunol. 1994. 6: 157-167.
-
(1994)
Int. Immunol.
, vol.6
, pp. 157-167
-
-
Gately, M.K.1
Warrier, R.R.2
Honasoge, S.3
Carvajal, D.M.4
Faherty, D.A.5
Connaughton, S.E.6
Anderson, T.D.7
Sarmiento, U.8
Hubbard, B.R.9
Murphy, M.10
-
35
-
-
0028593449
-
Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors
-
Chouaib, S., Chehimi, J., Bani, L., Genetet, N., Tursz, T., Gay, F., Trinchieri, G. and Mami-Chouaib, F., Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors. Proc. Natl. Acad. Sci. USA 1994. 91: 12659-12663.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12659-12663
-
-
Chouaib, S.1
Chehimi, J.2
Bani, L.3
Genetet, N.4
Tursz, T.5
Gay, F.6
Trinchieri, G.7
Mami-Chouaib, F.8
-
36
-
-
0027491655
-
+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming
-
+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 1993. 90: 10188-10192.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10188-10192
-
-
Seder, R.A.1
Gazzinelli, R.2
Sher, A.3
Paul, W.E.4
-
38
-
-
0027409793
-
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells
-
Manetti, R., Parronchi, P., Giudizi, M. G., Piccinni, M. P., Maggi, E., Trinchieri, G. and Romagnani, S., Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J. Exp. Med. 1993. 177: 1199-1204.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1199-1204
-
-
Manetti, R.1
Parronchi, P.2
Giudizi, M.G.3
Piccinni, M.P.4
Maggi, E.5
Trinchieri, G.6
Romagnani, S.7
-
39
-
-
0022338699
-
DNA binding to human leukocytes. Evidence for a receptor-mediated association, internalization and degradation of DNA
-
Bennett, R. M., Gabor, G. T. and Merritt, M. M., DNA binding to human leukocytes. Evidence for a receptor-mediated association, internalization and degradation of DNA. J. Clin. Invest. 1985. 76: 2182-2190.
-
(1985)
J. Clin. Invest.
, vol.76
, pp. 2182-2190
-
-
Bennett, R.M.1
Gabor, G.T.2
Merritt, M.M.3
|