메뉴 건너뛰기




Volumn 2, Issue 2, 2007, Pages 129-143

Potential utilization of bystander/abscopal-mediated signal transduction events in the treatment of solid tumors

Author keywords

Abscopal; Bystander; Cancer therapeutics; Carcinogenesis; Radiation; Signal transduction

Indexed keywords

ADENOVIRUS VECTOR; CARMUSTINE; CLUSTERIN; CYCLOPHOSPHAMIDE; CYTARABINE; EARLY GROWTH RESPONSE FACTOR 1; EPIDERMAL GROWTH FACTOR RECEPTOR; FAS LIGAND; FLT3 LIGAND; FLUDARABINE PHOSPHATE; GANCICLOVIR; GAP JUNCTION PROTEIN; GEMCITABINE; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; IRINOTECAN; MITOMYCIN C; MYC PROTEIN; NUCLEAR RECEPTOR NUR77; NUCLEIC ACID; PROTEIN BAX; PROTEIN P53; RETINOIC ACID; SINGLET OXYGEN; SOMATOMEDIN C; THYMIDINE KINASE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNINDEXED DRUG;

EID: 34249284167     PISSN: 15743624     EISSN: None     Source Type: Journal    
DOI: 10.2174/157436207780619509     Document Type: Review
Times cited : (28)

References (155)
  • 1
    • 0242658588 scopus 로고    scopus 로고
    • Genomic instability and bystander effects: A historical perspective
    • Little JB. Genomic instability and bystander effects: A historical perspective. Oncogene 2003; 22: 6978-87.
    • (2003) Oncogene , vol.22 , pp. 6978-6987
    • Little, J.B.1
  • 3
    • 1642304957 scopus 로고    scopus 로고
    • A theoretical approach to the role and critical issues associated with bystander effect in risk estimation
    • Nikjoo H, Khvostunov IK. A theoretical approach to the role and critical issues associated with bystander effect in risk estimation. Hum Exp Toxicol 2004; 23: 81-6.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 81-86
    • Nikjoo, H.1    Khvostunov, I.K.2
  • 4
    • 1642347163 scopus 로고    scopus 로고
    • Classical radiation biology dogma, bystander effects and paradigm shifts
    • Waldren CA. Classical radiation biology dogma, bystander effects and paradigm shifts. Hum Exp Toxicol 2004; 23: 95-100.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 95-100
    • Waldren, C.A.1
  • 5
    • 0345269096 scopus 로고    scopus 로고
    • Radiation abscopad antitumor effect is mediated through p53
    • Camphausen K, Moses MA, Menard C, et al. Radiation abscopad antitumor effect is mediated through p53. Cancer Res 2003; 63: 1990-3.
    • (2003) Cancer Res , vol.63 , pp. 1990-1993
    • Camphausen, K.1    Moses, M.A.2    Menard, C.3
  • 7
    • 0028898695 scopus 로고
    • The abscopal effect and chronic lymphocytic leukemia
    • Sham RL. The abscopal effect and chronic lymphocytic leukemia. Am J Med 1995; 98: 307-8.
    • (1995) Am J Med , vol.98 , pp. 307-308
    • Sham, R.L.1
  • 8
    • 0014558950 scopus 로고
    • The abscopal effect in malignant lymphoma and its relationship to lymphocyte circulation
    • Nobler MP. The abscopal effect in malignant lymphoma and its relationship to lymphocyte circulation. Radiology 1969; 93: 410-2.
    • (1969) Radiology , vol.93 , pp. 410-412
    • Nobler, M.P.1
  • 9
    • 0016816906 scopus 로고
    • An interesting case of possible abscopal effect in malignant melanoma
    • Kingsley DP. An interesting case of possible abscopal effect in malignant melanoma. Br J Radiol 1975; 48: 863-6.
    • (1975) Br J Radiol , vol.48 , pp. 863-866
    • Kingsley, D.P.1
  • 10
    • 0020657530 scopus 로고
    • Abscopal regression following radiotherapy for adenocarcinoma
    • Rees GJ, Ross CM. Abscopal regression following radiotherapy for adenocarcinoma. Br J Radiol 1983; 56: 63-6.
    • (1983) Br J Radiol , vol.56 , pp. 63-66
    • Rees, G.J.1    Ross, C.M.2
  • 13
    • 0026454677 scopus 로고
    • Induction of sister chromatid exchanges by extremely low doses of alpha-particles
    • Nagasawa H, Little JB. Induction of sister chromatid exchanges by extremely low doses of alpha-particles. Cancer Res 1992; 52: 6394-6.
    • (1992) Cancer Res , vol.52 , pp. 6394-6396
    • Nagasawa, H.1    Little, J.B.2
  • 15
    • 1642360160 scopus 로고    scopus 로고
    • Review of radiation-induced bystander effects
    • Snyder AR. Review of radiation-induced bystander effects. Hum Exp Toxicol 2004; 23: 87-9.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 87-89
    • Snyder, A.R.1
  • 17
    • 0035895240 scopus 로고    scopus 로고
    • Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha-particle irradiated to nonirradiated cells
    • Azzam EI, de Toledo SM, Little JB. Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha-particle irradiated to nonirradiated cells. Proc Natl Acad Sci USA 2001; 98: 473-8.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 473-478
    • Azzam, E.I.1    de Toledo, S.M.2    Little, J.B.3
  • 18
    • 0031936163 scopus 로고    scopus 로고
    • Cell-cell contact during gamma irradiation is not required to induce a bystander effect in normal human keratinocytes: Evidence for release during irradiation of a signal controlling survival into the medium
    • Mothersill C, Seymour CB, Cell-cell contact during gamma irradiation is not required to induce a bystander effect in normal human keratinocytes: Evidence for release during irradiation of a signal controlling survival into the medium. Radiat Res 1998; 149: 256-62.
    • (1998) Radiat Res , vol.149 , pp. 256-262
    • Mothersill, C.1    Seymour, C.B.2
  • 19
    • 1642293481 scopus 로고    scopus 로고
    • Commentary on radiation-induced bystander effects
    • Wright EG. Commentary on radiation-induced bystander effects. Hum Exp Toxicol 2004; 23: 91-4.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 91-94
    • Wright, E.G.1
  • 20
    • 1242315588 scopus 로고    scopus 로고
    • Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated
    • Demaria S, Ng B, Devitt ML, et al. Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. Int J Radiat Oncol Biol Phys 2004; 58: 862-70.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 862-870
    • Demaria, S.1    Ng, B.2    Devitt, M.L.3
  • 21
    • 0026510329 scopus 로고
    • Tumor eradication by adoptive transfer of cytotoxic t lymphocytes
    • Melief CJ. Tumor eradication by adoptive transfer of cytotoxic t lymphocytes. Adv Cancer Res 1992; 58: 143-75.
    • (1992) Adv Cancer Res , vol.58 , pp. 143-175
    • Melief, C.J.1
  • 22
    • 0033572416 scopus 로고    scopus 로고
    • Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer
    • Chakravarty PK, Alfieri A, Thomas EK, et al. Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer. Cancer Res 1999; 59: 6028-32.
    • (1999) Cancer Res , vol.59 , pp. 6028-6032
    • Chakravarty, P.K.1    Alfieri, A.2    Thomas, E.K.3
  • 24
    • 20444380697 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase accelerates postoperative tumor growth by inhibiting apoptosis and enhancing resistance to chemotherapy-induced apoptosis. Novel role for an old enemy
    • Coffey JC, Wang JH, Smith MJ, et al. Phosphoinositide 3-kinase accelerates postoperative tumor growth by inhibiting apoptosis and enhancing resistance to chemotherapy-induced apoptosis. Novel role for an old enemy. J Biol Chem 2005; 280: 20968-77.
    • (2005) J Biol Chem , vol.280 , pp. 20968-20977
    • Coffey, J.C.1    Wang, J.H.2    Smith, M.J.3
  • 25
    • 0028951043 scopus 로고
    • Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
    • Holmgren L, O'Reilly MS, Folkman J. Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression. Nat Med 1995; 1: 149-53.
    • (1995) Nat Med , vol.1 , pp. 149-153
    • Holmgren, L.1    O'Reilly, M.S.2    Folkman, J.3
  • 26
    • 0032713893 scopus 로고    scopus 로고
    • The role of endotoxin/lipopolysaccharide in surgically induced tumour growth in a murine model of metastatic disease
    • Pidgeon GP, Harmey JH, Kay E, Da Costa M, Redmond HP, Bouchier-Hayes DJ. The role of endotoxin/lipopolysaccharide in surgically induced tumour growth in a murine model of metastatic disease. Br J Cancer 1999; 81: 1311-7.
    • (1999) Br J Cancer , vol.81 , pp. 1311-1317
    • Pidgeon, G.P.1    Harmey, J.H.2    Kay, E.3    Da Costa, M.4    Redmond, H.P.5    Bouchier-Hayes, D.J.6
  • 27
    • 18044402671 scopus 로고    scopus 로고
    • Phase i study of gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas
    • Gururangan S, Cokgor L, Rich JN, et al. Phase i study of gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas. Neuro-oncol 2001; 3: 246-50.
    • (2001) Neuro-oncol , vol.3 , pp. 246-250
    • Gururangan, S.1    Cokgor, L.2    Rich, J.N.3
  • 28
    • 1342308418 scopus 로고    scopus 로고
    • Pattern of recurrence following local chemotherapy with biodegradable carmustine (bcnu) implants in patients with glioblastoma
    • Giese A, Kucinski T, Knepp U, et al. Pattern of recurrence following local chemotherapy with biodegradable carmustine (bcnu) implants in patients with glioblastoma. J Neurooncol 2004; 66: 351-60.
    • (2004) J Neurooncol , vol.66 , pp. 351-360
    • Giese, A.1    Kucinski, T.2    Knepp, U.3
  • 29
    • 0036310748 scopus 로고    scopus 로고
    • Pharmacokinetics of the carmustine implant
    • Fleming AB, Saltzman WM. Pharmacokinetics of the carmustine implant. Clin Pharmacokinet 2002; 41: 403-19.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 403-419
    • Fleming, A.B.1    Saltzman, W.M.2
  • 31
    • 0034086660 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene therapy for human cancer
    • Fujiwara T, Kataoka M, Tanaka N. Adenovirus-mediated p53 gene therapy for human cancer. Mol Urol 2000; 4: 51-4.
    • (2000) Mol Urol , vol.4 , pp. 51-54
    • Fujiwara, T.1    Kataoka, M.2    Tanaka, N.3
  • 32
    • 25444474137 scopus 로고    scopus 로고
    • Introduction to the background, principles, and state of the art in suicide gene therapy
    • Niculescu-Duvaz I, Springer CJ. Introduction to the background, principles, and state of the art in suicide gene therapy. Mol Biotechnol 2005; 30: 71-88.
    • (2005) Mol Biotechnol , vol.30 , pp. 71-88
    • Niculescu-Duvaz, I.1    Springer, C.J.2
  • 33
    • 8644280287 scopus 로고    scopus 로고
    • Tumor-activated prodrugs-a new approach to cancer therapy
    • Denny WA. Tumor-activated prodrugs-a new approach to cancer therapy. Cancer Invest 2004; 22: 604-19.
    • (2004) Cancer Invest , vol.22 , pp. 604-619
    • Denny, W.A.1
  • 35
    • 0036674989 scopus 로고    scopus 로고
    • Adenoviral mediated suicide gene transfer in the treatment of pancreatic cancer
    • Pan X, Li Z, Xu G, et al. Adenoviral mediated suicide gene transfer in the treatment of pancreatic cancer. Clin Med J (Engl) 2002; 115: 1205-8.
    • (2002) Clin Med J (Engl) , vol.115 , pp. 1205-1208
    • Pan, X.1    Li, Z.2    Xu, G.3
  • 36
    • 34249292429 scopus 로고    scopus 로고
    • Cancer gene therapy; adenoviral-mediated delivery of herpes simplex virus thymidine kinase gene selectively sensitizes human ovarian carcinoma cells to ganciclovir
    • Curiel DT, Michael, SI. Cancer gene therapy; "adenoviral-mediated delivery of herpes simplex virus thymidine kinase gene selectively sensitizes human ovarian carcinoma cells to ganciclovir. Cancer Biotechnology Weekly 1996; 22.
    • (1996) Cancer Biotechnology Weekly , pp. 22
    • Curiel, D.T.1    Michael, S.I.2
  • 37
    • 0030668915 scopus 로고    scopus 로고
    • A "distant" bystander effect of suicide gene therapy: Regression of nontransduced tumors together with a distant transduced tumor
    • Kianmanesh AR, Perrin H, Paris Y, et al. A "distant" bystander effect of suicide gene therapy: Regression of nontransduced tumors together with a distant transduced tumor. Hum Gene Ther 1997; 8: 1807-14.
    • (1997) Hum Gene Ther , vol.8 , pp. 1807-1814
    • Kianmanesh, A.R.1    Perrin, H.2    Paris, Y.3
  • 38
    • 0029159918 scopus 로고
    • Spatial and temporal control of gene therapy using ionizing radiation
    • Hallahan DE, Mauceri HJ, Seung LP, et al. Spatial and temporal control of gene therapy using ionizing radiation. Nat Med 1995; 1: 786-91.
    • (1995) Nat Med , vol.1 , pp. 786-791
    • Hallahan, D.E.1    Mauceri, H.J.2    Seung, L.P.3
  • 39
    • 18644363002 scopus 로고    scopus 로고
    • Combining radiotherapy with gene therapy (from the bench to the bedside): A novel treatment strategy for prostate cancer
    • Teh BS, Aguilar-Cordova E, Vlachaki MT, et al. Combining radiotherapy with gene therapy (from the bench to the bedside): A novel treatment strategy for prostate cancer. Oncologist 2002; 7: 458-66.
    • (2002) Oncologist , vol.7 , pp. 458-466
    • Teh, B.S.1    Aguilar-Cordova, E.2    Vlachaki, M.T.3
  • 40
    • 0031951530 scopus 로고    scopus 로고
    • Adenoviral tnf-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft
    • Staba MJ, Mauceri HJ, Kufe DW, Hallahan DE, Weichselbaum RR. Adenoviral tnf-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft. Gene Ther 1998; 5: 293-300.
    • (1998) Gene Ther , vol.5 , pp. 293-300
    • Staba, M.J.1    Mauceri, H.J.2    Kufe, D.W.3    Hallahan, D.E.4    Weichselbaum, R.R.5
  • 41
    • 0035324310 scopus 로고    scopus 로고
    • Bystander effects in cell death induced by photodynamic treatment uva radiation and inhibitors of atp synthesis
    • Dahle J, Angell-Petersen E, Steen HB, Moan J. Bystander effects in cell death induced by photodynamic treatment uva radiation and inhibitors of atp synthesis. Photochem Photobiol 2001; 73: 378-87.
    • (2001) Photochem Photobiol , vol.73 , pp. 378-387
    • Dahle, J.1    Angell-Petersen, E.2    Steen, H.B.3    Moan, J.4
  • 43
    • 0033822193 scopus 로고    scopus 로고
    • Gap junctional intercellular communication is not a major mediator in the bystander effect in photodynamic, treatment of mdck ii cells
    • Dable J, Mikalsen SO, Rivedal E, Steen HB. Gap junctional intercellular communication is not a major mediator in the bystander effect in photodynamic, treatment of mdck ii cells. Radiat Res 2000; 154: 331-41.
    • (2000) Radiat Res , vol.154 , pp. 331-341
    • Dable, J.1    Mikalsen, S.O.2    Rivedal, E.3    Steen, H.B.4
  • 44
    • 5644280149 scopus 로고    scopus 로고
    • Modulation of gene expression in human central nervous system tumors under methionine deprivation-induced stress
    • Kokkinakis DM, Liu X, Chada S, et al. Modulation of gene expression in human central nervous system tumors under methionine deprivation-induced stress. Cancer Res 2004; 64: 7513-25.
    • (2004) Cancer Res , vol.64 , pp. 7513-7525
    • Kokkinakis, D.M.1    Liu, X.2    Chada, S.3
  • 45
    • 0042803052 scopus 로고
    • The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture
    • Halpern BC, Clark BF, Hardy DN, Halpern RM, Smith RM. The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture. Proc Natl Acad Sci USA 1974; 71: 1133-6.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 1133-1136
    • Halpern, B.C.1    Clark, B.F.2    Hardy, D.N.3    Halpern, R.M.4    Smith, R.M.5
  • 47
    • 0037083273 scopus 로고    scopus 로고
    • Loss of mda-7 expression with progression of melanoma
    • Ellerhorst JA, Prieto VG, Ekmekcioglu S, et al. Loss of mda-7 expression with progression of melanoma. J Clin Oncol 2002; 20: 1069-74.
    • (2002) J Clin Oncol , vol.20 , pp. 1069-1074
    • Ellerhorst, J.A.1    Prieto, V.G.2    Ekmekcioglu, S.3
  • 48
    • 0037162507 scopus 로고    scopus 로고
    • Mda-7 (il-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the gadd family of genes by means of p38 mapk
    • Sarkar D, Su ZZ, Lebedeva IV, et al. Mda-7 (il-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the gadd family of genes by means of p38 mapk. Proc Natl Acad Sci USA 2002; 99: 10054-9.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10054-10059
    • Sarkar, D.1    Su, Z.Z.2    Lebedeva, I.V.3
  • 49
    • 0035793568 scopus 로고    scopus 로고
    • Ionizing radiation down-regulates p53 protein in primary egr-1 -/- mouse embryonic fibroblast cells causing enhanced resistance to apoptosis
    • Das A, Chendil D, Dey S, et al. Ionizing radiation down-regulates p53 protein in primary egr-1 -/- mouse embryonic fibroblast cells causing enhanced resistance to apoptosis. J Biol Chem 2001; 276: 3279-86.
    • (2001) J Biol Chem , vol.276 , pp. 3279-3286
    • Das, A.1    Chendil, D.2    Dey, S.3
  • 50
    • 1542514781 scopus 로고    scopus 로고
    • Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors
    • Ahmed MM. Regulation of radiation-induced apoptosis by early growth response-1 gene in solid tumors. Curr Cancer Drug Targets 2004; 4: 43-52.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 43-52
    • Ahmed, M.M.1
  • 51
    • 0141706537 scopus 로고    scopus 로고
    • Egr-1 target genes in human endothelial cells identified by microarray analysis
    • Fu M, Zhu X, Zhang J, et al. Egr-1 target genes in human endothelial cells identified by microarray analysis. Gene 2003; 315: 33-41.
    • (2003) Gene , vol.315 , pp. 33-41
    • Fu, M.1    Zhu, X.2    Zhang, J.3
  • 52
    • 0028938688 scopus 로고
    • Sensitization of human renal cell carcinoma cells to cis-diamminedichloroplatinum(ii) by anti-interleukin 6 monoclonal antibody or anti-interleukin 6 receptor monoclonal antibody
    • Mizutani Y, Bonavida B, Koishihara Y, Akamatsu K, Ohsugi Y, Yoshida O. Sensitization of human renal cell carcinoma cells to cis-diamminedichloroplatinum(ii) by anti-interleukin 6 monoclonal antibody or anti-interleukin 6 receptor monoclonal antibody. Cancer Res 1995; 55: 590-6.
    • (1995) Cancer Res , vol.55 , pp. 590-596
    • Mizutani, Y.1    Bonavida, B.2    Koishihara, Y.3    Akamatsu, K.4    Ohsugi, Y.5    Yoshida, O.6
  • 53
    • 0024386426 scopus 로고
    • Interleukin-6 (il-6) Inactions as an in vitro autocrine growth factor in renal cell carcinomas
    • Miki S, Iwano M, Miki Y, et al. Interleukin-6 (il-6) Inactions as an in vitro autocrine growth factor in renal cell carcinomas. FEBS Lett 1989; 250: 607-10.
    • (1989) FEBS Lett , vol.250 , pp. 607-610
    • Miki, S.1    Iwano, M.2    Miki, Y.3
  • 54
    • 25444510834 scopus 로고    scopus 로고
    • Interleukin-6 activates serum and glucocorticoid kinase via a p38 {alpha} mitogen activated protein kinase pathway
    • Meng F, Yamagiwa Y, Taffetani S, Han J, Patel T. Interleukin-6 activates serum and glucocorticoid kinase via a p38 {alpha} mitogen activated protein kinase pathway. Am J Physiol Cell Physiol 2005; 289: C971-81.
    • (2005) Am J Physiol Cell Physiol , vol.289
    • Meng, F.1    Yamagiwa, Y.2    Taffetani, S.3    Han, J.4    Patel, T.5
  • 55
    • 0038235872 scopus 로고    scopus 로고
    • Interleukin-6, cd45 and the src-kinases in myeloma cell proliferation
    • Ishikawa H, Tsuyama N, Abroun S, et al. Interleukin-6, cd45 and the src-kinases in myeloma cell proliferation. Leuk Lymphoma 2003; 44: 1477-81.
    • (2003) Leuk Lymphoma , vol.44 , pp. 1477-1481
    • Ishikawa, H.1    Tsuyama, N.2    Abroun, S.3
  • 56
    • 17044384183 scopus 로고    scopus 로고
    • Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma
    • Moran DM, Mayes N, Koniaris LG, Cahill PA, McKillop IH. Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma. Liver Int 2005; 25: 445-57.
    • (2005) Liver Int , vol.25 , pp. 445-457
    • Moran, D.M.1    Mayes, N.2    Koniaris, L.G.3    Cahill, P.A.4    McKillop, I.H.5
  • 57
    • 19344377123 scopus 로고    scopus 로고
    • Uv induced bystander signaling leading to apoptosis
    • Banerjee G, Gupta N, Kapoor A, Raman G. Uv induced bystander signaling leading to apoptosis. Cancer Lett 2005; 223: 275-94.
    • (2005) Cancer Lett , vol.223 , pp. 275-294
    • Banerjee, G.1    Gupta, N.2    Kapoor, A.3    Raman, G.4
  • 58
    • 7644238657 scopus 로고    scopus 로고
    • Ir-inducible clusterin gene expression: A protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects
    • Klokov D, Criswell T, Leskov KS, Araki S, Mayo L, Boothman DA. Ir-inducible clusterin gene expression: A protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects. Mutat Res 2004; 568: 97-110.
    • (2004) Mutat Res , vol.568 , pp. 97-110
    • Klokov, D.1    Criswell, T.2    Leskov, K.S.3    Araki, S.4    Mayo, L.5    Boothman, D.A.6
  • 59
    • 0036675428 scopus 로고    scopus 로고
    • Radiation-induced effects in unirradiated cells: A review and implications in cancer
    • Goldberg Z, Lehnert BE. Radiation-induced effects in unirradiated cells: A review and implications in cancer. Int J Oncol 2002; 21: 337-49.
    • (2002) Int J Oncol , vol.21 , pp. 337-349
    • Goldberg, Z.1    Lehnert, B.E.2
  • 60
    • 1642319697 scopus 로고    scopus 로고
    • The radiation-induced bystander effect: Evidence and significance
    • Azzam EI, Little JB. The radiation-induced bystander effect: Evidence and significance. Hum Exp Toxicol 2004; 23: 61-5.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 61-65
    • Azzam, E.I.1    Little, J.B.2
  • 61
    • 0034161938 scopus 로고    scopus 로고
    • Factors underlying the cell growth-related bystander responses to alpha particles
    • Iyer R, Lehnert BE, Svensson R. Factors underlying the cell growth-related bystander responses to alpha particles. Cancer Res 2000; 60: 1290-8.
    • (2000) Cancer Res , vol.60 , pp. 1290-1298
    • Iyer, R.1    Lehnert, B.E.2    Svensson, R.3
  • 62
    • 0036736438 scopus 로고    scopus 로고
    • Nitric oxide-mediated bystander effect induced by heavy-ions in human salivary gland tumour cells
    • Shao C, Furusawa, Y, Aoki M, Matsumoto H, Ando K. Nitric oxide-mediated bystander effect induced by heavy-ions in human salivary gland tumour cells. Int J Radiat Biol 2002; 78: 837-44.
    • (2002) Int J Radiat Biol , vol.78 , pp. 837-844
    • Shao, C.1    Furusawa, Y.2    Aoki, M.3    Matsumoto, H.4    Ando, K.5
  • 64
    • 0346725840 scopus 로고    scopus 로고
    • Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes
    • Valdes F, Murillo MM, Valverde AM, et al. Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes. Exp Cell Res 2004; 292: 209-18.
    • (2004) Exp Cell Res , vol.292 , pp. 209-218
    • Valdes, F.1    Murillo, M.M.2    Valverde, A.M.3
  • 65
    • 0035196587 scopus 로고    scopus 로고
    • Transforming growth factor beta enhances epithelial cell survival via akt-dependent regulation of fkhrll
    • Shin I, Bakin AV, Rodeck U, Brunet A, Arteaga CL. Transforming growth factor beta enhances epithelial cell survival via akt-dependent regulation of fkhrll. Mod Biol Cell 2001; 12: 3328-39.
    • (2001) Mod Biol Cell , vol.12 , pp. 3328-3339
    • Shin, I.1    Bakin, A.V.2    Rodeck, U.3    Brunet, A.4    Arteaga, C.L.5
  • 66
    • 0034791087 scopus 로고    scopus 로고
    • Transforming growth factor betal (tgf-beta1) promotes endothelial cell survival during in vitro angiogencsis via an autocrine mechanism implicating tgf-alpha signaling
    • Vitals F, Pouyssegur J. Transforming growth factor betal (tgf-beta1) promotes endothelial cell survival during in vitro angiogencsis via an autocrine mechanism implicating tgf-alpha signaling. Mol Cell Biol 2001; 21: 7218-30.
    • (2001) Mol Cell Biol , vol.21 , pp. 7218-7230
    • Vitals, F.1    Pouyssegur, J.2
  • 67
    • 4344664011 scopus 로고    scopus 로고
    • A sustained activation of pi3k/nf-kappab pathway is critical for the survival of chronic lymphocytic leukemia b cells
    • Cuni S, Perez-Aciego P, Perez-Chacon G, et al. A sustained activation of pi3k/nf-kappab pathway is critical for the survival of chronic lymphocytic leukemia b cells. Leukemia 2004; 18: 1391-400.
    • (2004) Leukemia , vol.18 , pp. 1391-1400
    • Cuni, S.1    Perez-Aciego, P.2    Perez-Chacon, G.3
  • 68
    • 0034909730 scopus 로고    scopus 로고
    • Use of antisense oligonucleotides targeting the antiapoptotic gene, clusterin/ testosterone-repressed prostate message 2, to enhance androgen sensitivity and chemosensitivity in prostate cancer
    • Gleave ME, Miyake H, Zellweger T, et al. Use of antisense oligonucleotides targeting the antiapoptotic gene, clusterin/ testosterone-repressed prostate message 2, to enhance androgen sensitivity and chemosensitivity in prostate cancer. Urology 2001; 58: 39-49.
    • (2001) Urology , vol.58 , pp. 39-49
    • Gleave, M.E.1    Miyake, H.2    Zellweger, T.3
  • 69
    • 0034705103 scopus 로고    scopus 로고
    • Nuclear clusterin/ xip8, an xray-induced ku70-binding protein that signals cell death
    • Yang CR, Leskov K, Hosley-Eberlein K, et al. Nuclear clusterin/ xip8, an xray-induced ku70-binding protein that signals cell death. Proc Natl Acad Sci USA 2000; 97: 5907-12.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5907-5912
    • Yang, C.R.1    Leskov, K.2    Hosley-Eberlein, K.3
  • 70
    • 0033565594 scopus 로고    scopus 로고
    • Transforming growth factor beta regulates clusterin gene expression via modulation of transcription factor c-fos
    • Jin G, Howe PH. Transforming growth factor beta regulates clusterin gene expression via modulation of transcription factor c-fos. Eur J Biochem 1999; 263: 534-42.
    • (1999) Eur J Biochem , vol.263 , pp. 534-542
    • Jin, G.1    Howe, P.H.2
  • 71
    • 2342566706 scopus 로고    scopus 로고
    • Repression of irinducible clusterin expression by the p53 tumor suppressor protein
    • Criswell T, Klokov D, Beman M, Lavik JP, Boothman DA. Repression of irinducible clusterin expression by the p53 tumor suppressor protein. Cancer Biol Ther 2003; 2: 372-80.
    • (2003) Cancer Biol Ther , vol.2 , pp. 372-380
    • Criswell, T.1    Klokov, D.2    Beman, M.3    Lavik, J.P.4    Boothman, D.A.5
  • 72
    • 0029018581 scopus 로고
    • Identification of glycoprotein 330 as an endocytie receptor for apolipoprotein j/ clusterin
    • Kounnas MZ, Loukinova EB, Stefansson S, et al. Identification of glycoprotein 330 as an endocytie receptor for apolipoprotein j/ clusterin. J Biol Chem 1995; 270: 13070-5.
    • (1995) J Biol Chem , vol.270 , pp. 13070-13075
    • Kounnas, M.Z.1    Loukinova, E.B.2    Stefansson, S.3
  • 73
    • 0035890306 scopus 로고    scopus 로고
    • Multiple receptors mediate apoj-dependent clearance of cellular debris into nonprofessional phagocytes
    • Bartl MM, Luckenbach T, Bergner O, Ullrich O, Koch-Brandt C. Multiple receptors mediate apoj-dependent clearance of cellular debris into nonprofessional phagocytes. Exp Cell Res 2001; 271: 130-41.
    • (2001) Exp Cell Res , vol.271 , pp. 130-141
    • Bartl, M.M.1    Luckenbach, T.2    Bergner, O.3    Ullrich, O.4    Koch-Brandt, C.5
  • 74
    • 0035102484 scopus 로고    scopus 로고
    • Induction of radioresistance by a nitric oxide-mediated bystander effect
    • Matsumoto H, Hayashi S, Hatashita M, et al. Induction of radioresistance by a nitric oxide-mediated bystander effect. Radiat Res 2001; 155: 387-96.
    • (2001) Radiat Res , vol.155 , pp. 387-396
    • Matsumoto, H.1    Hayashi, S.2    Hatashita, M.3
  • 75
    • 0036149168 scopus 로고    scopus 로고
    • Alpha-particle-induced increases in the radio-resistance of normal human bystander cells
    • Iyer R, Lehnert BE. Alpha-particle-induced increases in the radio-resistance of normal human bystander cells. Radiat Res 2002; 157: 3-7.
    • (2002) Radiat Res , vol.157 , pp. 3-7
    • Iyer, R.1    Lehnert, B.E.2
  • 76
    • 0037134767 scopus 로고    scopus 로고
    • Low dose, low-let ionizing radiation-induced radioadapration and associated early responses in unirradiated cells
    • Iyer R, Lehnert BE. Low dose, low-let ionizing radiation-induced radioadapration and associated early responses in unirradiated cells. Mutat Res 2002; 503: 1-9.
    • (2002) Mutat Res , vol.503 , pp. 1-9
    • Iyer, R.1    Lehnert, B.E.2
  • 77
    • 0028277737 scopus 로고
    • In vivo radiation protection by nitric oxide modulation
    • Liebmann J, DeLuca AM, Coffin D, et al. In vivo radiation protection by nitric oxide modulation. Cancer Res 1994; 54: 3365-8.
    • (1994) Cancer Res , vol.54 , pp. 3365-3368
    • Liebmann, J.1    DeLuca, A.M.2    Coffin, D.3
  • 79
    • 9244232804 scopus 로고    scopus 로고
    • Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53
    • Forrester K, Ambs S, Lupold SE, et al. Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. Proc Natl Acad Sci USA 1996; 93: 2442-7.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2442-2447
    • Forrester, K.1    Ambs, S.2    Lupold, S.E.3
  • 80
    • 0029079360 scopus 로고
    • Binding between wild-type p53 and hsp72 accumulated after uv and gamma-ray irradiation
    • Matsumoto H, Wang X, Ohnishi T. Binding between wild-type p53 and hsp72 accumulated after uv and gamma-ray irradiation. Cancer Lett 1995; 92: 127-33.
    • (1995) Cancer Lett , vol.92 , pp. 127-133
    • Matsumoto, H.1    Wang, X.2    Ohnishi, T.3
  • 81
    • 0031808112 scopus 로고    scopus 로고
    • Low-dose irradiation induces expression of heat shock protein 70 mma and thermo- and radio-resistance in myeloid leukemia cell line
    • Ibuki Y, Hayashi A, Suzuki A, Goto R. Low-dose irradiation induces expression of heat shock protein 70 mma and thermo- and radio-resistance in myeloid leukemia cell line. Biol Pharm Bull 1998; 21: 434-9.
    • (1998) Biol Pharm Bull , vol.21 , pp. 434-439
    • Ibuki, Y.1    Hayashi, A.2    Suzuki, A.3    Goto, R.4
  • 82
    • 0030869505 scopus 로고    scopus 로고
    • P53-dependent induction of waf1 by a low-ph culture condition in human glioblastoma cells
    • Ohtsubo T, Wang X, Takahashi A, et al. P53-dependent induction of waf1 by a low-ph culture condition in human glioblastoma cells. Cancer Res 1997; 57: 3910-3.
    • (1997) Cancer Res , vol.57 , pp. 3910-3913
    • Ohtsubo, T.1    Wang, X.2    Takahashi, A.3
  • 83
    • 0028242807 scopus 로고
    • Cytokine-induced modulation of tumor suppressor gene expression in ovarian cancer cells: Up-regulation of p53 gene expression and induction of apoptosis by tumor necrosis factor-alpha
    • discussion 8-30
    • Gotlieb WH, Watson JM, Rezai A, Johnson M, Martinez-Maza O, Berek JS. Cytokine-induced modulation of tumor suppressor gene expression in ovarian cancer cells: Up-regulation of p53 gene expression and induction of apoptosis by tumor necrosis factor-alpha. Am J Obstet Gynecol 1994; 170: 1121-8; discussion 8-30.
    • (1994) Am J Obstet Gynecol , vol.170 , pp. 1121-1128
    • Gotlieb, W.H.1    Watson, J.M.2    Rezai, A.3    Johnson, M.4    Martinez-Maza, O.5    Berek, J.S.6
  • 85
    • 0031868114 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in human pancreatic carcinoma cell lines is associated with a g1-arrest and an increase ofthe cyclin-dependent kinase inhibitor p21 waf1/cip1
    • Gansauge S, Nussler AK, Beger HG, Gansauge F. Nitric oxide-induced apoptosis in human pancreatic carcinoma cell lines is associated with a g1-arrest and an increase ofthe cyclin-dependent kinase inhibitor p21 waf1/cip1. Cell Growth Differ 1998; 9: 611-7.
    • (1998) Cell Growth Differ , vol.9 , pp. 611-617
    • Gansauge, S.1    Nussler, A.K.2    Beger, H.G.3    Gansauge, F.4
  • 86
    • 0242658550 scopus 로고    scopus 로고
    • Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect
    • Azzam EI, de Toledo SM, Little JB. Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect. Oncogene 2003; 22: 7050-7.
    • (2003) Oncogene , vol.22 , pp. 7050-7057
    • Azzam, E.I.1    de Toledo, S.M.2    Little, J.B.3
  • 87
    • 20444490003 scopus 로고    scopus 로고
    • Bystander signaling between glioma cells and fibroblasts targeted with counted particles
    • Shao C, Folkard M, Michael BD, Prise KM. Bystander signaling between glioma cells and fibroblasts targeted with counted particles. Int J Cancer 2005; 116: 45-51.
    • (2005) Int J Cancer , vol.116 , pp. 45-51
    • Shao, C.1    Folkard, M.2    Michael, B.D.3    Prise, K.M.4
  • 89
    • 0036286183 scopus 로고    scopus 로고
    • Hematologic consequences of exposure to ionizing radiation
    • Dainiak N. Hematologic consequences of exposure to ionizing radiation. Exp Hematol 2002; 30: 513-28.
    • (2002) Exp Hematol , vol.30 , pp. 513-528
    • Dainiak, N.1
  • 90
    • 12844280474 scopus 로고    scopus 로고
    • Abdominal radiation exposure elicits inflammatory responses and abscopal effects in the lungs of mice
    • Van der Meeren A, Monti P, Vandamme M, Squiban C, Wysocki J, Griffiths N. Abdominal radiation exposure elicits inflammatory responses and abscopal effects in the lungs of mice. Radiat Res 2005; 163: 144-52.
    • (2005) Radiat Res , vol.163 , pp. 144-152
    • Van der Meeren, A.1    Monti, P.2    Vandamme, M.3    Squiban, C.4    Wysocki, J.5    Griffiths, N.6
  • 91
    • 0017126775 scopus 로고
    • Cross-priming for a secondary cytotoxic response to minor h antigens with h-2 congenic cells which do not cross-react in the cytotoxic assay
    • Bevan MJ. Cross-priming for a secondary cytotoxic response to minor h antigens with h-2 congenic cells which do not cross-react in the cytotoxic assay. J Exp Med 1976; 143: 1283-8.
    • (1976) J Exp Med , vol.143 , pp. 1283-1288
    • Bevan, M.J.1
  • 92
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting mhc class i-restricted tumor antigens
    • Huang AY, Golumbek P, Ahmadzadeh M, Jaffee E, Pardoll D, Levitsky H. Role of bone marrow-derived cells in presenting mhc class i-restricted tumor antigens. Science 1994; 264: 961-5.
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.Y.1    Golumbek, P.2    Ahmadzadeh, M.3    Jaffee, E.4    Pardoll, D.5    Levitsky, H.6
  • 93
    • 0029661945 scopus 로고    scopus 로고
    • Dramatic increase in the numbers of functionally mature dendritic cells in flt3 ligand-treated mice: Multiple dendritic cell subpopulations identified
    • Maraskovsky E, Brasel K, Teepe M, et al. Dramatic increase in the numbers of functionally mature dendritic cells in flt3 ligand-treated mice: Multiple dendritic cell subpopulations identified. J Exp Med 1996; 184: 1953-62.
    • (1996) J Exp Med , vol.184 , pp. 1953-1962
    • Maraskovsky, E.1    Brasel, K.2    Teepe, M.3
  • 94
    • 0033658372 scopus 로고    scopus 로고
    • Regulation of tnfrsf6 (fas) expression in ataxia telangiectasia cells by ionizing radiation
    • Albanese J, Dainiak N. Regulation of tnfrsf6 (fas) expression in ataxia telangiectasia cells by ionizing radiation. Radial Res 2000; 154: 616-24.
    • (2000) Radial Res , vol.154 , pp. 616-624
    • Albanese, J.1    Dainiak, N.2
  • 95
    • 25444482596 scopus 로고    scopus 로고
    • Relationship between the expression of connexin43 and bystander effect of suicide gene therapy in ovarian cancer
    • Zhang A, Wang Q, Han Z, et al. Relationship between the expression of connexin43 and bystander effect of suicide gene therapy in ovarian cancer. J Huazhong Univ Sci Technolog Med Sci 2004; 24: 476-9.
    • (2004) J Huazhong Univ Sci Technolog Med Sci , vol.24 , pp. 476-479
    • Zhang, A.1    Wang, Q.2    Han, Z.3
  • 96
    • 0036023759 scopus 로고    scopus 로고
    • Early events in the apoptotic cascade initiated in cells treated with medium from the progeny of irradiated cells
    • Lyng FM, Seymour CB, Mothersill C. Early events in the apoptotic cascade initiated in cells treated with medium from the progeny of irradiated cells. Radiat Prot Dosimetry 2002; 99: 169-72.
    • (2002) Radiat Prot Dosimetry , vol.99 , pp. 169-172
    • Lyng, F.M.1    Seymour, C.B.2    Mothersill, C.3
  • 97
    • 14344266100 scopus 로고    scopus 로고
    • The death-inducing effect and genomic instability
    • Nagar S, Morgan WF. The death-inducing effect and genomic instability. Radiat Res 2005; 163: 316-23.
    • (2005) Radiat Res , vol.163 , pp. 316-323
    • Nagar, S.1    Morgan, W.F.2
  • 98
    • 0036210491 scopus 로고    scopus 로고
    • Initiation of apoptosis in cells exposed to medium from the progeny of irradiated cells: A possible mechanism for bystander-induced genomic instability?
    • Lyng FM, Seymour CB, Mothersill C. Initiation of apoptosis in cells exposed to medium from the progeny of irradiated cells: A possible mechanism for bystander-induced genomic instability? Radiat Res 2002; 157; 365-70.
    • (2002) Radiat Res , vol.157 , pp. 365-370
    • Lyng, F.M.1    Seymour, C.B.2    Mothersill, C.3
  • 99
    • 15544365506 scopus 로고    scopus 로고
    • Medium from irradiated cells induces dose-dependent mitochondrial changes and bcl2 responses in unirradiated human keratinocytes
    • Maguire P, Mothersill, C, Seymour C, Lyng FM. Medium from irradiated cells induces dose-dependent mitochondrial changes and bcl2 responses in unirradiated human keratinocytes. Radiat Res 2005; 163: 384-90.
    • (2005) Radiat Res , vol.163 , pp. 384-390
    • Maguire, P.1    Mothersill, C.2    Seymour, C.3    Lyng, F.M.4
  • 100
    • 0036032079 scopus 로고    scopus 로고
    • Surgery for gastric cancer increases plasma levels of vascular endothelial growth factor and von willebrand factor
    • Ikeda M, Furukawa H, Immarum H, et al. Surgery for gastric cancer increases plasma levels of vascular endothelial growth factor and von willebrand factor. Gastric Cancer 2002; 5: 137-41.
    • (2002) Gastric Cancer , vol.5 , pp. 137-141
    • Ikeda, M.1    Furukawa, H.2    Immarum, H.3
  • 101
    • 0032252634 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increased by pulmonary surgery accelerates the growth of micrometastases in metastatic lung cancer
    • Maniwa Y, Okada M, Ishii N, Kiyooka K. Vascular endothelial growth factor increased by pulmonary surgery accelerates the growth of micrometastases in metastatic lung cancer. Chest 1998; 114: 1668-75.
    • (1998) Chest , vol.114 , pp. 1668-1675
    • Maniwa, Y.1    Okada, M.2    Ishii, N.3    Kiyooka, K.4
  • 102
    • 0028829267 scopus 로고
    • Adhesive receptors expressed by tumor cells and platelets: Novel targets for therapeutic anti-metastatic strategies
    • Olcksowicz L, Dutcher JP. Adhesive receptors expressed by tumor cells and platelets: Novel targets for therapeutic anti-metastatic strategies. Med Oncol 1995; 12: 95-102.
    • (1995) Med Oncol , vol.12 , pp. 95-102
    • Olcksowicz, L.1    Dutcher, J.P.2
  • 103
    • 4644284921 scopus 로고    scopus 로고
    • Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylasc gene
    • Hong JS, Waud WR, Levasseur ON, et al. Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylasc gene. Cancer Res 2004; 64: 6610-5.
    • (2004) Cancer Res , vol.64 , pp. 6610-6615
    • Hong, J.S.1    Waud, W.R.2    Levasseur, O.N.3
  • 105
    • 17044398835 scopus 로고    scopus 로고
    • Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma
    • Stefani AL, Barzon L, Castagliuolo I, et al. Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma. J Hepatol 2005; 42: 728-35.
    • (2005) J Hepatol , vol.42 , pp. 728-735
    • Stefani, A.L.1    Barzon, L.2    Castagliuolo, I.3
  • 106
    • 0043130148 scopus 로고    scopus 로고
    • Cell to cell contact required for bystander effect of the tnf-related apoptosis-inducing ligand (trail) gene
    • Huang X, Lin T, Gu J, et al. Cell to cell contact required for bystander effect of the tnf-related apoptosis-inducing ligand (trail) gene. Int J Oncol 2003; 22: 1241-5.
    • (2003) Int J Oncol , vol.22 , pp. 1241-1245
    • Huang, X.1    Lin, T.2    Gu, J.3
  • 108
    • 0036097227 scopus 로고    scopus 로고
    • Viral-mediated gene transfer for cancer treatment
    • Wilson DR. Viral-mediated gene transfer for cancer treatment. Curr Pharm Biotechnol 2002; 3: 151-64.
    • (2002) Curr Pharm Biotechnol , vol.3 , pp. 151-164
    • Wilson, D.R.1
  • 109
    • 0024853567 scopus 로고
    • Herpes simplex virus type 1 and human DNA polymerase interactions with 2′-deoxyguanosine 5′-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition
    • Reardon JE. Herpes simplex virus type 1 and human DNA polymerase interactions with 2′-deoxyguanosine 5′-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition. J Biol Chem 1989; 264: 19039-44.
    • (1989) J Biol Chem , vol.264 , pp. 19039-19044
    • Reardon, J.E.1
  • 110
    • 0024041143 scopus 로고
    • Antiviral activity and mechanism of action of ganciclovir
    • Matthews T, Boehme R. Antiviral activity and mechanism of action of ganciclovir. Rev Infect Dis 1988; 10(Suppl 3): S490-4.
    • (1988) Rev Infect Dis , vol.10 , Issue.SUPPL. 3
    • Matthews, T.1    Boehme, R.2
  • 111
    • 0029884088 scopus 로고    scopus 로고
    • Cytogenetic genotoxicity of antiherpes virostatics in chinese hamster v79-e cells. I. Purine nucleoside analogues
    • Thust R, Schacke M, Wutzler P. Cytogenetic genotoxicity of antiherpes virostatics in chinese hamster v79-e cells. I. Purine nucleoside analogues. Antiviral Res 1996; 31: 105-13.
    • (1996) Antiviral Res , vol.31 , pp. 105-113
    • Thust, R.1    Schacke, M.2    Wutzler, P.3
  • 112
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW, Ram Z, Wallbridge S, Ishii H, Oldfield EH, Blaese RM. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992; 256: 1550-2.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 113
    • 0142259327 scopus 로고    scopus 로고
    • All-trans retinoic acid augments the bystander effect of herpes simplex virus thymidine kinase/ganciclovir system in the treatment of tongue carcinoma cell line]
    • Wang AX, Huang HZ. [All-trans retinoic acid augments the bystander effect of herpes simplex virus thymidine kinase/ganciclovir system in the treatment of tongue carcinoma cell line]. Zhonghua Kou Qiang Yi Xue Za Zhi 2003; 38: 24-6.
    • (2003) Zhonghua Kou Qiang Yi Xue Za Zhi , vol.38 , pp. 24-26
    • Wang, A.X.1    Huang, H.Z.2
  • 114
    • 0036196733 scopus 로고    scopus 로고
    • The effect of all-trans retinoic acid on gap junctional intercellular communication and connexin 43 gene expression in glioma cells
    • Zhang X, Ren Z, Zuo J, et al. The effect of all-trans retinoic acid on gap junctional intercellular communication and connexin 43 gene expression in glioma cells. Chin Med Sci J 2002; 17: 22-6.
    • (2002) Chin Med Sci J , vol.17 , pp. 22-26
    • Zhang, X.1    Ren, Z.2    Zuo, J.3
  • 115
    • 0027483695 scopus 로고
    • The "bystander effect": Tumor regression when a fraction of the tumor mass is genetically modified
    • Freeman SM, Abboud CN, Whartenby KA, et al. The "bystander effect": Tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993; 53: 5274-83.
    • (1993) Cancer Res , vol.53 , pp. 5274-5283
    • Freeman, S.M.1    Abboud, C.N.2    Whartenby, K.A.3
  • 116
    • 0033532533 scopus 로고    scopus 로고
    • Tentative novel mechanism of the bystander effect in glioma gene therapy with hsv-dc/gcv system
    • Bai S, Du L, Liu W, Whittle IR, He L. Tentative novel mechanism of the bystander effect in glioma gene therapy with hsv-dc/gcv system. Biochem Biophys Res Commun 1999; 259: 455-9.
    • (1999) Biochem Biophys Res Commun , vol.259 , pp. 455-459
    • Bai, S.1    Du, L.2    Liu, W.3    Whittle, I.R.4    He, L.5
  • 117
    • 0035106088 scopus 로고    scopus 로고
    • Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis
    • Agard C, Ligeza C, Dupas B, et al. Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis. Cancer Gene Ther 2001; 8: 128-36.
    • (2001) Cancer Gene Ther , vol.8 , pp. 128-136
    • Agard, C.1    Ligeza, C.2    Dupas, B.3
  • 118
    • 10344230407 scopus 로고    scopus 로고
    • Bystander activity of ad-mda7: Human mda-7 protein kills melanoma cells via an il-20 receptor-dependent but stat3-independent mechanism
    • Chada S, Mhashilkar AM, Ramesh R, et al. Bystander activity of ad-mda7: Human mda-7 protein kills melanoma cells via an il-20 receptor-dependent but stat3-independent mechanism. Mol Ther 2004; 10: 1085-95.
    • (2004) Mol Ther , vol.10 , pp. 1085-1095
    • Chada, S.1    Mhashilkar, A.M.2    Ramesh, R.3
  • 119
    • 0035317682 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene-7 (mda-7): A novel anti-tumor gene for cancer gene therapy
    • Mhashilkar AM, Schrock RD, Hindi M, et al. Melanoma differentiation associated gene-7 (mda-7): A novel anti-tumor gene for cancer gene therapy. Mol Med 2001; 7: 271-82.
    • (2001) Mol Med , vol.7 , pp. 271-282
    • Mhashilkar, A.M.1    Schrock, R.D.2    Hindi, M.3
  • 120
    • 0037097637 scopus 로고    scopus 로고
    • The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory, activity and is designated il-24
    • Caudell EG, Mumm JB, Poindexter N, et al. The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory, activity and is designated il-24. J Immunol 2002; 168: 6041-6.
    • (2002) J Immunol , vol.168 , pp. 6041-6046
    • Caudell, E.G.1    Mumm, J.B.2    Poindexter, N.3
  • 121
    • 3042856164 scopus 로고    scopus 로고
    • Adenovirus-mediated mda-7 (il24) gene therapy suppresses angiogenesis and sensitizes nsclc xenograft tumors to radiation
    • Nishikawa T, Ramesh R, Munshi A, Chada S, Meyn RE. Adenovirus-mediated mda-7 (il24) gene therapy suppresses angiogenesis and sensitizes nsclc xenograft tumors to radiation. Mol Ther 2004; 9: 818-28.
    • (2004) Mol Ther , vol.9 , pp. 818-828
    • Nishikawa, T.1    Ramesh, R.2    Munshi, A.3    Chada, S.4    Meyn, R.E.5
  • 122
    • 0041513362 scopus 로고    scopus 로고
    • Melanoma differentiation-associated gene 7/interleukin (il)-24 is a novel ligand that regulates angiogenesis via the il-22 receptor
    • Ramesh R, Mhashilkar AM, Tanaka F, et al. Melanoma differentiation-associated gene 7/interleukin (il)-24 is a novel ligand that regulates angiogenesis via the il-22 receptor. Cancer Res 2003; 63: 5105-13.
    • (2003) Cancer Res , vol.63 , pp. 5105-5113
    • Ramesh, R.1    Mhashilkar, A.M.2    Tanaka, F.3
  • 123
    • 0041854247 scopus 로고    scopus 로고
    • Induction of chromosomal instability by chronic oxidative stress
    • Limoli CL, Giedzinski E. Induction of chromosomal instability by chronic oxidative stress. Neoplasia 2003; 5: 339-46.
    • (2003) Neoplasia , vol.5 , pp. 339-346
    • Limoli, C.L.1    Giedzinski, E.2
  • 125
    • 0034991065 scopus 로고    scopus 로고
    • Enhanced therapeutic effect of hsv-tk+gev gene therapy and ionizing radiation for prostate cancer
    • Chhikara M, Huang H, Vlachaki MT, et al. Enhanced therapeutic effect of hsv-tk+gev gene therapy and ionizing radiation for prostate cancer. Mol Ther 2001; 3: 536-42.
    • (2001) Mol Ther , vol.3 , pp. 536-542
    • Chhikara, M.1    Huang, H.2    Vlachaki, M.T.3
  • 127
    • 16644399070 scopus 로고    scopus 로고
    • Potential use of mda-7 as a biological adjuvant for radiation therapy
    • Sharcef MM, Kokkinakis DM, Ahmed MM. Potential use of mda-7 as a biological adjuvant for radiation therapy. Cancer Biol Ther 2004; 3: 752-4.
    • (2004) Cancer Biol Ther , vol.3 , pp. 752-754
    • Sharcef, M.M.1    Kokkinakis, D.M.2    Ahmed, M.M.3
  • 128
    • 13244294142 scopus 로고    scopus 로고
    • Mda-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells
    • Yacoub A, Mitchell C, Hong Y, et al. Mda-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells. Cancer Biol Ther 2004; 3: 739-51.
    • (2004) Cancer Biol Ther , vol.3 , pp. 739-751
    • Yacoub, A.1    Mitchell, C.2    Hong, Y.3
  • 129
    • 24644434502 scopus 로고    scopus 로고
    • Bystander effects, genomic instability, adaptive response, and cancer risk assessment for radiation and chemical exposures
    • Preston RJ. Bystander effects, genomic instability, adaptive response, and cancer risk assessment for radiation and chemical exposures. Toxicol Appl Pharmacol 2005; 207: 550-6.
    • (2005) Toxicol Appl Pharmacol , vol.207 , pp. 550-556
    • Preston, R.J.1
  • 131
    • 7644234070 scopus 로고    scopus 로고
    • Interrelationships amongst radiation-induced genomic instability, bystander effects, and the adaptive response
    • Kadhim MA, Moore SR, Goodwin EH. Interrelationships amongst radiation-induced genomic instability, bystander effects, and the adaptive response. Mutat Res 2004; 568: 21-32.
    • (2004) Mutat Res , vol.568 , pp. 21-32
    • Kadhim, M.A.1    Moore, S.R.2    Goodwin, E.H.3
  • 132
    • 0038640479 scopus 로고    scopus 로고
    • Non-targeted and delayed effects of exposure to ionizing radiation: Ii. Radiation-inducad genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects
    • Morgan WF. Non-targeted and delayed effects of exposure to ionizing radiation: Ii. Radiation-inducad genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiat Res 2003; 159: 581-96.
    • (2003) Radiat Res , vol.159 , pp. 581-596
    • Morgan, W.F.1
  • 133
    • 0038679329 scopus 로고    scopus 로고
    • Spontaneous regression of pulmonary metastases from renal cell carcinoma after radio frequency ablation of primary tumor: An in situ tumor vaccine?
    • Sanchez-Ortiz RF, Tannir N, Ahrar K, Wood CG. Spontaneous regression of pulmonary metastases from renal cell carcinoma after radio frequency ablation of primary tumor: An in situ tumor vaccine? J Urol 2003; 170: 178-9.
    • (2003) J Urol , vol.170 , pp. 178-179
    • Sanchez-Ortiz, R.F.1    Tannir, N.2    Ahrar, K.3    Wood, C.G.4
  • 134
    • 20344385768 scopus 로고    scopus 로고
    • Combination therapy with interleukin-6 receptor superantagonist sant7 and dexamethasone induces antitumor effects in a novel scid-hu in vivo model of human multiple myeloma
    • Tassone P, Neri P, Burger R, et al. Combination therapy with interleukin-6 receptor superantagonist sant7 and dexamethasone induces antitumor effects in a novel scid-hu in vivo model of human multiple myeloma. Clin Cancer Res 2005; 11: 4251-8.
    • (2005) Clin Cancer Res , vol.11 , pp. 4251-4258
    • Tassone, P.1    Neri, P.2    Burger, R.3
  • 135
    • 0029812490 scopus 로고    scopus 로고
    • Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death
    • Demartis A, Bernassola F, Savino R, Melino G, Ciliberto G. Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death. Cancer Res 1996; 56: 4213-8.
    • (1996) Cancer Res , vol.56 , pp. 4213-4218
    • Demartis, A.1    Bernassola, F.2    Savino, R.3    Melino, G.4    Ciliberto, G.5
  • 136
    • 9744240196 scopus 로고    scopus 로고
    • Molecular targeting: PI3 kinase pathway
    • Dancey JE. Molecular targeting: PI3 kinase pathway. Ann Oncol 2004; 15(Suppl 4): iv233-9.
    • (2004) Ann Oncol , vol.15 , Issue.SUPPL. 4
    • Dancey, J.E.1
  • 137
    • 0035744033 scopus 로고    scopus 로고
    • Mechanisms of resistance to rapamycins
    • Huang S, Houghton PJ. Mechanisms of resistance to rapamycins. Drug Resist Updat 2001; 4: 378-91.
    • (2001) Drug Resist Updat , vol.4 , pp. 378-391
    • Huang, S.1    Houghton, P.J.2
  • 138
    • 0141596941 scopus 로고    scopus 로고
    • Overview: Translating hsp90 biology into hsp90 drugs
    • Workman P. Overview: Translating hsp90 biology into hsp90 drugs. Curr Cancer Drug Targets 2003; 3: 297-300.
    • (2003) Curr Cancer Drug Targets , vol.3 , pp. 297-300
    • Workman, P.1
  • 140
    • 0036830256 scopus 로고    scopus 로고
    • Inhibitors of mtor reverse doxorubicin resistance conferred by pten status in prostate cancer cells
    • Grunwald V, DeGraffenried L, Russel D, Friedrichs WE, Ray RB, Hidalgo M. Inhibitors of mtor reverse doxorubicin resistance conferred by pten status in prostate cancer cells. Cancer Res 2002; 62: 6141-5.
    • (2002) Cancer Res , vol.62 , pp. 6141-6145
    • Grunwald, V.1    DeGraffenried, L.2    Russel, D.3    Friedrichs, W.E.4    Ray, R.B.5    Hidalgo, M.6
  • 141
    • 0031755688 scopus 로고    scopus 로고
    • Studies on the mechanism of resistance to rapamycin in human cancer cells
    • Hosoi H, Dilling MB, Liu LN, et al. Studies on the mechanism of resistance to rapamycin in human cancer cells. Mol Pharmacol 1998; 54: 815-24.
    • (1998) Mol Pharmacol , vol.54 , pp. 815-824
    • Hosoi, H.1    Dilling, M.B.2    Liu, L.N.3
  • 142
    • 1642535431 scopus 로고    scopus 로고
    • Akt activity determines sensitivity to mammalian target of rapamycin (mtor) inhibitors by regulating cyclin d1 and c-myc expression
    • Gera JF, Mellinghoff IK, Shi Y, et al. Akt activity determines sensitivity to mammalian target of rapamycin (mtor) inhibitors by regulating cyclin d1 and c-myc expression. J Biol Chem 2004; 279: 2737-46.
    • (2004) J Biol Chem , vol.279 , pp. 2737-2746
    • Gera, J.F.1    Mellinghoff, I.K.2    Shi, Y.3
  • 143
    • 14844293486 scopus 로고    scopus 로고
    • Synergistic antitumor effect of combined use of adenoviral-mediated p53 gene transfer and antisense oligodeoxynucleotide targeting clusterin gene in an androgen-independent human prostate cancer model
    • Yamanaka K, Gleave ME, Hara I, Muramaki M, Miyake H. Synergistic antitumor effect of combined use of adenoviral-mediated p53 gene transfer and antisense oligodeoxynucleotide targeting clusterin gene in an androgen-independent human prostate cancer model. Mol Cancer Ther 2005; 4: 187-95.
    • (2005) Mol Cancer Ther , vol.4 , pp. 187-195
    • Yamanaka, K.1    Gleave, M.E.2    Hara, I.3    Muramaki, M.4    Miyake, H.5
  • 144
    • 0034870685 scopus 로고    scopus 로고
    • Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the antiapoptotic gene clusterin
    • Zellweger T, Miyake H, July LV, Akbari M, Kiyama S, Gleave ME. Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the antiapoptotic gene clusterin. Neoplasia 2001; 3: 360-7.
    • (2001) Neoplasia , vol.3 , pp. 360-367
    • Zellweger, T.1    Miyake, H.2    July, L.V.3    Akbari, M.4    Kiyama, S.5    Gleave, M.E.6
  • 145
    • 15944390264 scopus 로고    scopus 로고
    • Use of antisense oligonucleotides targeting the cytoprotective gene, clusterin, to enhance androgen- and chemo-sensitivity in prostate cancer
    • Gleave M, Miyake H. Use of antisense oligonucleotides targeting the cytoprotective gene, clusterin, to enhance androgen- and chemo-sensitivity in prostate cancer. World J Urol 2005; 23: 38-46.
    • (2005) World J Urol , vol.23 , pp. 38-46
    • Gleave, M.1    Miyake, H.2
  • 146
    • 20344402686 scopus 로고    scopus 로고
    • Antisense clusterin oligodeoxynucleotides increase the response of her-2 gene amplified breast cancer cells to trastuzumab
    • Biroccio A, D'Angelo C, Jansen B, Gleave ME, Zupi G. Antisense clusterin oligodeoxynucleotides increase the response of her-2 gene amplified breast cancer cells to trastuzumab. J Cell Physiol 2005; 204: 463-9.
    • (2005) J Cell Physiol , vol.204 , pp. 463-469
    • Biroccio, A.1    D'Angelo, C.2    Jansen, B.3    Gleave, M.E.4    Zupi, G.5
  • 147
    • 2442565896 scopus 로고    scopus 로고
    • Synergistic antitumor activity by combined treatment with gemcitabine and antisense oligode-oxynucleotide targeting clusterin gene in an intravesical administration model against human bladder cancer kotcc-1 cells
    • Miyake H, Eto H, Hara I, So A, Li D, Gleave ME. Synergistic antitumor activity by combined treatment with gemcitabine and antisense oligode-oxynucleotide targeting clusterin gene in an intravesical administration model against human bladder cancer kotcc-1 cells. J Urol 2004; 171: 2477-81.
    • (2004) J Urol , vol.171 , pp. 2477-2481
    • Miyake, H.1    Eto, H.2    Hara, I.3    So, A.4    Li, D.5    Gleave, M.E.6
  • 148
    • 0031858774 scopus 로고    scopus 로고
    • Tumor volume: A basic and specific response predictor in radiotherapy
    • Dubben HH, Thames HD, Bcck-Bornholdt HP. Tumor volume: A basic and specific response predictor in radiotherapy. Radiother Oncol 1998; 47: 167-74.
    • (1998) Radiother Oncol , vol.47 , pp. 167-174
    • Dubben, H.H.1    Thames, H.D.2    Bcck-Bornholdt, H.P.3
  • 149
    • 0037992480 scopus 로고    scopus 로고
    • The impact of tnf-alpha induction on therapeutic efficacy following high dose spatially fractionated (grid) radiation
    • Sathishkumar S, Dey S, Meigooni AS, et al. The impact of tnf-alpha induction on therapeutic efficacy following high dose spatially fractionated (grid) radiation. Technol Cancer Res Treat 2002; 1: 141-7.
    • (2002) Technol Cancer Res Treat , vol.1 , pp. 141-147
    • Sathishkumar, S.1    Dey, S.2    Meigooni, A.S.3
  • 150
    • 27744607641 scopus 로고    scopus 로고
    • Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: Implications for endothelial apoptosis
    • Sathishkumar S, Boyanovsky B, Karakashian AA, et al. Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: Implications for endothelial apoptosis. Cancer Biol Ther 2005; 4: 979-86.
    • (2005) Cancer Biol Ther , vol.4 , pp. 979-986
    • Sathishkumar, S.1    Boyanovsky, B.2    Karakashian, A.A.3
  • 151
    • 2342499799 scopus 로고    scopus 로고
    • Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery
    • Wei J, Blum S, Unger M, et al. Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery. Cancer Cell 2004; 5: 477-88.
    • (2004) Cancer Cell , vol.5 , pp. 477-488
    • Wei, J.1    Blum, S.2    Unger, M.3
  • 152
    • 0034813202 scopus 로고    scopus 로고
    • Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice
    • Davidoff AM, Ng CY, Brown P, et al. Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice. Clin Cancer Res 2001; 7: 2870-9.
    • (2001) Clin Cancer Res , vol.7 , pp. 2870-2879
    • Davidoff, A.M.1    Ng, C.Y.2    Brown, P.3
  • 153
    • 0031965353 scopus 로고    scopus 로고
    • Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor
    • Lin P, Sankar S, Shan S, et al. Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ 1998; 9: 49-58.
    • (1998) Cell Growth Differ , vol.9 , pp. 49-58
    • Lin, P.1    Sankar, S.2    Shan, S.3
  • 154
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-ncgafive flk-1 mutant
    • Millauer B, Shawver LK, Plate KH, Risau W, Ullrich A. Glioblastoma growth inhibited in vivo by a dominant-ncgafive flk-1 mutant Nature 1994; 367: 576-9.
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 155
    • 0036844379 scopus 로고    scopus 로고
    • Bystander and delayed effects after fractionated radiation exposure
    • Mothersill C, Seymour CB. Bystander and delayed effects after fractionated radiation exposure. Radiat Res 2002; 158: 626-33.
    • (2002) Radiat Res , vol.158 , pp. 626-633
    • Mothersill, C.1    Seymour, C.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.