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Volumn 58, Issue 3, 2004, Pages 862-870

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

Author keywords

Antitumor immunity; Breast cancer; Dendritic cells; Flt3 Ligand; Ionizing radiation

Indexed keywords

CELLS; IONIZING RADIATION; RADIOTHERAPY; TUMORS;

EID: 1242315588     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2003.09.012     Document Type: Article
Times cited : (1151)

References (59)
  • 1
    • 0026510329 scopus 로고
    • Tumor eradication by adoptive transfer of cytotoxic T lymphocytes
    • Melief C.J.M. Tumor eradication by adoptive transfer of cytotoxic T lymphocytes. Adv Cancer Res. 58:1992;143-175.
    • (1992) Adv Cancer Res , vol.58 , pp. 143-175
    • Melief, C.J.M.1
  • 3
    • 0027078670 scopus 로고
    • Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
    • Chen L., Ashe S., Brady W.A., et al. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell. 71:1992;1093-1102.
    • (1992) Cell , vol.71 , pp. 1093-1102
    • Chen, L.1    Ashe, S.2    Brady, W.A.3
  • 4
    • 0027392843 scopus 로고
    • + T cells by B7-transfected melanoma cells
    • + T cells by B7-transfected melanoma cells. Science. 259:1993;368-370.
    • (1993) Science , vol.259 , pp. 368-370
    • Townsend, S.E.1    Allison, J.P.2
  • 5
    • 0017126775 scopus 로고
    • Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay
    • Bevan M.J. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J Exp Med. 143:1976;1283-1288.
    • (1976) J Exp Med , vol.143 , pp. 1283-1288
    • Bevan, M.J.1
  • 6
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
    • Huang A., Golumbek P., Ahmadzadeh M., et al. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science. 264:1994;961-965.
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.1    Golumbek, P.2    Ahmadzadeh, M.3
  • 7
    • 0036668249 scopus 로고    scopus 로고
    • Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses
    • Fonteneau J.F., Larsson M., Bhardwaj N. Interactions between dead cells and dendritic cells in the induction of antiviral CTL responses. Curr Opin Immunol. 14:2002;471-477.
    • (2002) Curr Opin Immunol , vol.14 , pp. 471-477
    • Fonteneau, J.F.1    Larsson, M.2    Bhardwaj, N.3
  • 8
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • Sauter B., Albert M.L., Francisco L., et al. Consequences of cell death Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells . J Exp Med. 191:2000;423-433.
    • (2000) J Exp Med , vol.191 , pp. 423-433
    • Sauter, B.1    Albert, M.L.2    Francisco, L.3
  • 9
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: Specialized and regulated antigen processing machines
    • Mellman I., Steinman R.M. Dendritic cells Specialized and regulated antigen processing machines . Cell. 106:2001;255-258.
    • (2001) Cell , vol.106 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 10
    • 0033010852 scopus 로고    scopus 로고
    • Molecular mechanisms of ionizing radiation-induced apoptosis
    • Watters D. Molecular mechanisms of ionizing radiation-induced apoptosis. Immunol Cell Biol. 77:1999;263-271.
    • (1999) Immunol Cell Biol , vol.77 , pp. 263-271
    • Watters, D.1
  • 11
    • 0028840285 scopus 로고
    • Induction of acute phase gene expression by brain irradiation
    • Hong J.H., Chiang C.S., Campbell I.L., et al. Induction of acute phase gene expression by brain irradiation. Int J Radiat Oncol Biol Phys. 33:1995;619-626.
    • (1995) Int J Radiat Oncol Biol Phys , vol.33 , pp. 619-626
    • Hong, J.H.1    Chiang, C.S.2    Campbell, I.L.3
  • 12
    • 0032726778 scopus 로고    scopus 로고
    • Rapid induction of cytokine gene expression in the lung after single and fractionated doses of radiation
    • Hong J.H., Chiang C.S., Tsao C.Y., et al. Rapid induction of cytokine gene expression in the lung after single and fractionated doses of radiation. Int J Radiat Biol. 75:1999;1421-1427.
    • (1999) Int J Radiat Biol , vol.75 , pp. 1421-1427
    • Hong, J.H.1    Chiang, C.S.2    Tsao, C.Y.3
  • 13
    • 0032969290 scopus 로고    scopus 로고
    • Radiation-induced normal tissue injury: Role of adhesion molecules in leukocyte-endothelial cell interactions
    • Quarmby S., Kumar P., Kumar S. Radiation-induced normal tissue injury Role of adhesion molecules in leukocyte-endothelial cell interactions . Int J Cancer. 82:1999;385-395.
    • (1999) Int J Cancer , vol.82 , pp. 385-395
    • Quarmby, S.1    Kumar, P.2    Kumar, S.3
  • 14
    • 0033828752 scopus 로고    scopus 로고
    • Radiation induces upregulation of cyclooxygenase-2 (COX-2) protein in PC-3 cells
    • Steinauer K.K., Gibbs I., Ning S., et al. Radiation induces upregulation of cyclooxygenase-2 (COX-2) protein in PC-3 cells. Int J Radiat Oncol Biol Phys. 48:2000;325-328.
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 325-328
    • Steinauer, K.K.1    Gibbs, I.2    Ning, S.3
  • 15
    • 0035892360 scopus 로고    scopus 로고
    • Combination of gamma-irradiation and dendritic cell administration induces a potent antitumor response in tumor-bearing mice: Approach to treatment of advanced stage cancer
    • Nikitina E.Y., Gabrilovich D.I. Combination of gamma-irradiation and dendritic cell administration induces a potent antitumor response in tumor-bearing mice Approach to treatment of advanced stage cancer . Int J Cancer. 94:2001;825-833.
    • (2001) Int J Cancer , vol.94 , pp. 825-833
    • Nikitina, E.Y.1    Gabrilovich, D.I.2
  • 16
    • 0036494443 scopus 로고    scopus 로고
    • Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication
    • Ganss R., Ryschich E., Klar E., et al. Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer Res. 62:2002;1462-1470.
    • (2002) Cancer Res , vol.62 , pp. 1462-1470
    • Ganss, R.1    Ryschich, E.2    Klar, E.3
  • 17
    • 0014558950 scopus 로고
    • The abscopal effect in malignant lymphoma and its relationship to lymphocyte circulation
    • Nobler M.P. The abscopal effect in malignant lymphoma and its relationship to lymphocyte circulation. Radiology. 93:1969;410-412.
    • (1969) Radiology , vol.93 , pp. 410-412
    • Nobler, M.P.1
  • 18
    • 0015598767 scopus 로고
    • Abscopal effect of radiation in papillary adenocarcinoma
    • Ehlers G., Fridman M. Abscopal effect of radiation in papillary adenocarcinoma. Br J Radiol. 46:1973;220-222.
    • (1973) Br J Radiol , vol.46 , pp. 220-222
    • Ehlers, G.1    Fridman, M.2
  • 19
    • 0016816906 scopus 로고
    • An interesting case of possible abscopal effect in malignant melanoma
    • Kingsley D.P. An interesting case of possible abscopal effect in malignant melanoma. Br J Radiol. 48:1975;863-866.
    • (1975) Br J Radiol , vol.48 , pp. 863-866
    • Kingsley, D.P.1
  • 20
    • 0017365178 scopus 로고
    • Lymphangiographic demonstration of the abscopal effect in patients with malignant lymphomas
    • Antoniades J., Brady L.W., Lightfoot D.A. Lymphangiographic demonstration of the abscopal effect in patients with malignant lymphomas. Int J Radiat Oncol Biol Phys. 2:1977;141-147.
    • (1977) Int J Radiat Oncol Biol Phys , vol.2 , pp. 141-147
    • Antoniades, J.1    Brady, L.W.2    Lightfoot, D.A.3
  • 21
    • 0019409515 scopus 로고
    • Abscopal regression in lymphoma: A mechanism in common with total body irradation?
    • Rees G.J. Abscopal regression in lymphoma A mechanism in common with total body irradation? Clin Radiol. 32:1981;475-480.
    • (1981) Clin Radiol , vol.32 , pp. 475-480
    • Rees, G.J.1
  • 22
    • 0028898695 scopus 로고
    • The abscopal effect and chronic lymphocytic leukemia
    • Sham R.L. The abscopal effect and chronic lymphocytic leukemia. Am J Med. 98:1995;307-308.
    • (1995) Am J Med , vol.98 , pp. 307-308
    • Sham, R.L.1
  • 23
    • 7344232177 scopus 로고    scopus 로고
    • Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis
    • Ohba K., Omagari K., Nakamura T., et al. Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis. Gut. 43:1998;575-577.
    • (1998) Gut , vol.43 , pp. 575-577
    • Ohba, K.1    Omagari, K.2    Nakamura, T.3
  • 24
    • 0013071190 scopus 로고
    • Whole body irradiation - Radiology or medicine?
    • Mole R.J. Whole body irradiation - radiology or medicine? Br J Radiol. 26:1953;234-241.
    • (1953) Br J Radiol , vol.26 , pp. 234-241
    • Mole, R.J.1
  • 25
    • 0024811559 scopus 로고
    • Effects of X-ray irradiation on natural killer (NK) cell system. I. Elevation of sensitivity of tumor cells and lytic function of NK cells
    • Uchida A., Mizutani Y., Nagamuta M., et al. Effects of X-ray irradiation on natural killer (NK) cell system. I. Elevation of sensitivity of tumor cells and lytic function of NK cells. Immunopharmacol Immunotoxicol. 11:1989;507-519.
    • (1989) Immunopharmacol Immunotoxicol , vol.11 , pp. 507-519
    • Uchida, A.1    Mizutani, Y.2    Nagamuta, M.3
  • 26
    • 0026542746 scopus 로고
    • Lymphoid irradiation results in long-term increases in natural killer cells in patients treated for Hodgkin's disease
    • Macklis R.M., Mauch P.M., Burakoff S.J., et al. Lymphoid irradiation results in long-term increases in natural killer cells in patients treated for Hodgkin's disease. Cancer. 69:1992;778-783.
    • (1992) Cancer , vol.69 , pp. 778-783
    • MacKlis, R.M.1    Mauch, P.M.2    Burakoff, S.J.3
  • 27
    • 0036301973 scopus 로고    scopus 로고
    • Immature myeloid cells and cancer-associated immune suppression
    • Kusmartsev S., Gabrilovich D.I. Immature myeloid cells and cancer-associated immune suppression. Cancer Immunol Immunother. 51:2002;293-298.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 293-298
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 28
    • 0025246123 scopus 로고
    • Radiosensitive barrier to T-cell-mediated adoptive immunotherapy of established tumors
    • Awwad M., North R.J. Radiosensitive barrier to T-cell-mediated adoptive immunotherapy of established tumors. Cancer Res. 50:1990;2228-2233.
    • (1990) Cancer Res , vol.50 , pp. 2228-2233
    • Awwad, M.1    North, R.J.2
  • 29
    • 0025058972 scopus 로고
    • Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action
    • Cameron R.B., Spiess P.J., Rosenberg S.A. Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action. J Exp Med. 171:1990;249-263.
    • (1990) J Exp Med , vol.171 , pp. 249-263
    • Cameron, R.B.1    Spiess, P.J.2    Rosenberg, S.A.3
  • 30
    • 0026757759 scopus 로고
    • Synergy of radiation therapy and immunotherapy in murine renal cell carcinoma
    • Dybal E.J., Haas G.P., Maughan R.L., et al. Synergy of radiation therapy and immunotherapy in murine renal cell carcinoma. J Urol. 148:1992;1331-1337.
    • (1992) J Urol , vol.148 , pp. 1331-1337
    • Dybal, E.J.1    Haas, G.P.2    Maughan, R.L.3
  • 31
    • 0029004324 scopus 로고
    • Radiation-induced effects on murine kidney tumor cells: Role in the interaction of local irradiation and immunotherapy
    • Younes E., Haas G.P., Dezso B., et al. Radiation-induced effects on murine kidney tumor cells Role in the interaction of local irradiation and immunotherapy . J Urol. 153:1995;2029-2033.
    • (1995) J Urol , vol.153 , pp. 2029-2033
    • Younes, E.1    Haas, G.P.2    Dezso, B.3
  • 32
    • 1842376251 scopus 로고    scopus 로고
    • Effects of IL-3 gene expression on tumor response to irradiation in vitro and in vivo
    • Chiang C.S., Syljuasen R.G., Hong J.H., et al. Effects of IL-3 gene expression on tumor response to irradiation in vitro and in vivo. Cancer Res. 57:1997;3899-3903.
    • (1997) Cancer Res , vol.57 , pp. 3899-3903
    • Chiang, C.S.1    Syljuasen, R.G.2    Hong, J.H.3
  • 33
    • 0029661945 scopus 로고    scopus 로고
    • Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: Multiple dendritic cell subpopulations identified
    • Maraskovsky E., Brasel K., Teepe M., et al. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice Multiple dendritic cell subpopulations identified . J Exp Med. 184:1996;1953-1962.
    • (1996) J Exp Med , vol.184 , pp. 1953-1962
    • Maraskovsky, E.1    Brasel, K.2    Teepe, M.3
  • 34
    • 0030952766 scopus 로고    scopus 로고
    • Flt3 ligand induces tumor regression and anti-tumor immune responses in vivo
    • Lynch D.H., Andreasen A., Maraskovsky E., et al. Flt3 ligand induces tumor regression and anti-tumor immune responses in vivo. Nat Med. 3:1997;625-631.
    • (1997) Nat Med , vol.3 , pp. 625-631
    • Lynch, D.H.1    Andreasen, A.2    Maraskovsky, E.3
  • 35
    • 0033572416 scopus 로고    scopus 로고
    • Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer
    • Chakravarty P.K., Alfieri A., Thomas E.K., et al. Flt3-ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer. Cancer Res. 59:1999;6028-6032.
    • (1999) Cancer Res , vol.59 , pp. 6028-6032
    • Chakravarty, P.K.1    Alfieri, A.2    Thomas, E.K.3
  • 36
    • 0031947875 scopus 로고    scopus 로고
    • Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase III randomized Intergroup study 0099
    • Al-Sarraf M., LeBlanc M., Giri P.G., et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer Phase III randomized Intergroup study 0099 . J Clin Oncol. 16:1998;1310-1317.
    • (1998) J Clin Oncol , vol.16 , pp. 1310-1317
    • Al-Sarraf, M.1    Leblanc, M.2    Giri, P.G.3
  • 37
    • 0032858243 scopus 로고    scopus 로고
    • Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer
    • Furuse K., Fukuoka M., Kawahara M., et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. J Clin Oncol. 17:1999;2692-2699.
    • (1999) J Clin Oncol , vol.17 , pp. 2692-2699
    • Furuse, K.1    Fukuoka, M.2    Kawahara, M.3
  • 38
    • 0012658014 scopus 로고    scopus 로고
    • Concurrent chemo-radiation for cervical cancer
    • Washington DC
    • National Cancer Institute. Concurrent chemo-radiation for cervical cancer. Clinical announcement. Washington DC; 1999.
    • (1999) Clinical Announcement
  • 39
    • 1242266434 scopus 로고    scopus 로고
    • Clinical course of locally advanced breast cancer (LABC) patients with pathological response to primary concurrent 5-fluorouracil and radiation (FU/RT)
    • Formenti S.C., Cohen D., Tsao-Wei D.D., et al. Clinical course of locally advanced breast cancer (LABC) patients with pathological response to primary concurrent 5-fluorouracil and radiation (FU/RT). Int J Radiat Oncol Biol Phys. 51:2001;195-196.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 195-196
    • Formenti, S.C.1    Cohen, D.2    Tsao-Wei, D.D.3
  • 40
    • 0026503190 scopus 로고
    • Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor
    • Aslakson C.J., Miller F.R. Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res. 52:1992;1399-1405.
    • (1992) Cancer Res , vol.52 , pp. 1399-1405
    • Aslakson, C.J.1    Miller, F.R.2
  • 41
    • 0018388062 scopus 로고
    • Establishment and characterization of BALB/c lymphoma lines with B cell properties
    • Kim K.J., Kanellopoulos-Langevin C., Merwin R.M., et al. Establishment and characterization of BALB/c lymphoma lines with B cell properties. J Immunol. 122:1979;549-554.
    • (1979) J Immunol , vol.122 , pp. 549-554
    • Kim, K.J.1    Kanellopoulos-Langevin, C.2    Merwin, R.M.3
  • 42
    • 0033012030 scopus 로고    scopus 로고
    • An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
    • Lutz M.B., Kukutsch N., Ogilvie A.L.J., et al. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods. 223:1999;77-92.
    • (1999) J Immunol Methods , vol.223 , pp. 77-92
    • Lutz, M.B.1    Kukutsch, N.2    Ogilvie, A.L.J.3
  • 43
    • 0345269096 scopus 로고    scopus 로고
    • Radiation abscopal antitumor effect is mediated through p53
    • Camphausen K., Moses M.A., Menard C., et al. Radiation abscopal antitumor effect is mediated through p53. Cancer Res. 63:2003;1990-1993.
    • (2003) Cancer Res , vol.63 , pp. 1990-1993
    • Camphausen, K.1    Moses, M.A.2    Menard, C.3
  • 44
    • 0027982995 scopus 로고
    • Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity
    • Chen L., McGowan P., Ashe S., et al. Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity. J Exp Med. 179:1994;523-532.
    • (1994) J Exp Med , vol.179 , pp. 523-532
    • Chen, L.1    McGowan, P.2    Ashe, S.3
  • 45
    • 9444225462 scopus 로고    scopus 로고
    • Heterogeneous effects of B7-1 and B7-2 in the induction of both protective and therapeutic anti-tumor immunity against different mouse tumors
    • Martin-Fontecha A., Cavallo F., Bellone M., et al. Heterogeneous effects of B7-1 and B7-2 in the induction of both protective and therapeutic anti-tumor immunity against different mouse tumors. Eur J Immunol. 26:1996;1851-1859.
    • (1996) Eur J Immunol , vol.26 , pp. 1851-1859
    • Martin-Fontecha, A.1    Cavallo, F.2    Bellone, M.3
  • 46
    • 0025937123 scopus 로고
    • Radiation enhances tumor necrosis factor alpha production by murine brain cells
    • Chiang C.S., McBride W.H. Radiation enhances tumor necrosis factor alpha production by murine brain cells. Brain Res. 566:1991;265-269.
    • (1991) Brain Res , vol.566 , pp. 265-269
    • Chiang, C.S.1    McBride, W.H.2
  • 47
    • 0032720264 scopus 로고    scopus 로고
    • Differential regulation by IL-4 and IL-10 of radiation-induced IL-6 and IL-8 production and ICAM-1 expression by human endothelial cells
    • Van Der Meeren A., Squiban C., Gourmelon P., et al. Differential regulation by IL-4 and IL-10 of radiation-induced IL-6 and IL-8 production and ICAM-1 expression by human endothelial cells. Cytokine. 11:1999;831-838.
    • (1999) Cytokine , vol.11 , pp. 831-838
    • Van Der Meeren, A.1    Squiban, C.2    Gourmelon, P.3
  • 48
    • 0036785631 scopus 로고    scopus 로고
    • Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model
    • Heckelsmiller K., Rall K., Beck S., et al. Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model. J Immunol. 169:2002;3892-3899.
    • (2002) J Immunol , vol.169 , pp. 3892-3899
    • Heckelsmiller, K.1    Rall, K.2    Beck, S.3
  • 49
    • 0037428675 scopus 로고    scopus 로고
    • Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18
    • Hashimoto W., Tanaka F., Robbins P.D., et al. Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18. Int J Cancer. 103:2003;508-513.
    • (2003) Int J Cancer , vol.103 , pp. 508-513
    • Hashimoto, W.1    Tanaka, F.2    Robbins, P.D.3
  • 50
    • 18644375874 scopus 로고    scopus 로고
    • In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens
    • Jung S., Unutmaz D., Wong P., et al. In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity. 17:2002;211-220.
    • (2002) Immunity , vol.17 , pp. 211-220
    • Jung, S.1    Unutmaz, D.2    Wong, P.3
  • 51
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • Gabrilovich D.I., Chen H.L., Girgis K.R., et al. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med. 2:1996;1096-1103.
    • (1996) Nat Med , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3
  • 52
    • 0030934973 scopus 로고    scopus 로고
    • Decreased antigen presentation by dendritic cells in patients with breast cancer
    • Gabrilovich D.I., Corak J., Ciernik I.F., et al. Decreased antigen presentation by dendritic cells in patients with breast cancer. Clin Cancer Res. 3:1997;483-490.
    • (1997) Clin Cancer Res , vol.3 , pp. 483-490
    • Gabrilovich, D.I.1    Corak, J.2    Ciernik, I.F.3
  • 53
    • 0035339932 scopus 로고    scopus 로고
    • Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells
    • Gabrilovich D.I., Velders M.P., Sotomayor E.M., et al. Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells. J Immunol. 166:2001;5398-5406.
    • (2001) J Immunol , vol.166 , pp. 5398-5406
    • Gabrilovich, D.I.1    Velders, M.P.2    Sotomayor, E.M.3
  • 54
    • 0141456030 scopus 로고    scopus 로고
    • Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity
    • 15
    • Melani C, Chiodoni C, Forni G, et al. Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity. Blood 2003;May 15; [epub ahead of print].
    • (2003) Blood
    • Melani, C.1    Chiodoni, C.2    Forni, G.3
  • 55
    • 0035164478 scopus 로고    scopus 로고
    • Increased production of immature myeloid cells in cancer patients as a mechanism of immunosuppression in cancer
    • Almand B., Clark J., Nikitina E.Y., et al. Increased production of immature myeloid cells in cancer patients as a mechanism of immunosuppression in cancer. J Immunol. 166:2001;678-689.
    • (2001) J Immunol , vol.166 , pp. 678-689
    • Almand, B.1    Clark, J.2    Nikitina, E.Y.3
  • 56
    • 0034125451 scopus 로고    scopus 로고
    • Clinical significance of defective dendritic cell differentiation in cancer
    • Almand B., Resser J., Lindman B., et al. Clinical significance of defective dendritic cell differentiation in cancer. Clin Cancer Res. 6:2000;1755-1766.
    • (2000) Clin Cancer Res , vol.6 , pp. 1755-1766
    • Almand, B.1    Resser, J.2    Lindman, B.3
  • 57
    • 0033562982 scopus 로고    scopus 로고
    • Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation
    • Bronte V., Chappell D.B., Apolloni E., et al. Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation. J Immunol. 162:1999;5728-5737.
    • (1999) J Immunol , vol.162 , pp. 5728-5737
    • Bronte, V.1    Chappell, D.B.2    Apolloni, E.3
  • 58
    • 0034235748 scopus 로고    scopus 로고
    • Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo
    • Pulendran B., Banchereau J., Burkeholder S., et al. Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo. J Immunol. 165:2000;566-572.
    • (2000) J Immunol , vol.165 , pp. 566-572
    • Pulendran, B.1    Banchereau, J.2    Burkeholder, S.3
  • 59
    • 0033818096 scopus 로고    scopus 로고
    • The dendritic cell and human cancer vaccines
    • Dallal R.M., Lotze M.T. The dendritic cell and human cancer vaccines. Curr Opin Immunol. 12:2000;583-588.
    • (2000) Curr Opin Immunol , vol.12 , pp. 583-588
    • Dallal, R.M.1    Lotze, M.T.2


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