Gene-modified PA1-STK cells home to tumor sites in patients with malignant pleural mesothelioma

Annals of Thoracic Surgery

Volumn 70, Issue 2, 2000, Pages 407-411

  Harrison Jr , Lynn H ^a   Schwarzenberger, Paul O ^a   Byrne, Patrick S ^a   Marrogi, Aizen J ^a   Kolls, Jay K ^a   McCarthy, Kevin E ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TECHNETIUM 99M; THYMIDINE KINASE;

ARTICLE; CANCER CELL CULTURE; CASE REPORT; CELL ADHESION; CELL LABELING; CELL MIGRATION; CELL TRANSPORT; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DNA MODIFICATION; GENE EXPRESSION; GENE THERAPY; HUMAN; HUMAN CELL; ISOTOPE LABELING; PLEURA MESOTHELIOMA; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SUICIDE GENE;

FEMALE; GENE THERAPY; HUMANS; MESOTHELIOMA; OVARIAN NEOPLASMS; PLEURAL NEOPLASMS; RADIOPHARMACEUTICALS; SIMPLEXVIRUS; TECHNETIUM COMPOUNDS; THYMIDINE KINASE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0033836342     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(00)01557-5     Document Type: Article

References (11)

1. The 'by-stander effect': Tumor regression when a fraction of the tumor mass is genetically modified
2. Treatment of ovarian cancer using gene-modified vaccine
3. Antitumor activity with the HSV-tk-gene-modified cell line PA1-STK in malignant mesothelioma
4. The treatment of malignant mesothelioma with a gene-modified cancer cell line: Phase I study
5. Randomized Phase II trial of cisplatin with mitomycin or doxorubicin for malignant mesothelioma by the Cancer and Leukemia Group B
6. The treatment of malignant mesothelioma of the pleura: Review of a 5-year experience with special reference to radiotherapy
7. Intrapleural photodynamic therapy: Results of Phase I trial
8. Multimodality management of malignant pleural mesothelioma
9. Tumor necrosis factor induces hemorrhagic necrosis of a sarcoma
10. Enhanced tumor recognition and killing using the HSV-tk suicide gene