Abdominal radiation exposure elicits inflammatory responses and abscopal effects in the lungs of mice

Radiation Research

Volumn 163, Issue 2, 2005, Pages 144-152

  Van Der Meeren, A ^b   Monti, P ^a   Vandamme, M ^a   Squiban, C ^a   Wysocki, J ^a   Griffiths, N ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^b CEA DIF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE; CYTOKINE; ENROFLOXACIN; FIBRINOGEN; INTERLEUKIN 6; MESSENGER RNA; PADGEM PROTEIN; PROSTAGLANDIN E2; THROMBOMODULIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA; VON WILLEBRAND FACTOR;

ABDOMEN; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINE; LUNG; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION SICKNESS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WHOLE BODY RADIATION; X IRRADIATION;

ABDOMEN; ANIMALS; ENTERITIS; INTESTINES; JEJUNUM; LUNG; MALE; MICE; MICE, INBRED C57BL; RADIATION INJURIES; RADIATION PNEUMONITIS; WHOLE-BODY IRRADIATION;

EID: 12844280474     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR3293     Document Type: Article

References (49)

1. P. Rubin, C. J. Johnston, J. P. Williams, S. McDonald and J. N. Finkelstein, A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis. Int. J. Radiat. Oncol. Biol. Phys. 33, 99-109 (1995).
2. M. G. Buell and R. K. Harding, Proinflammatory effects of local abdominal irradiation on rat gastrointestinal tract. Digestive Dis. Sci. 345, 390-399 (1989).
3. Y. Ikeda, M. Ito, M. Matsuu, K. Shichijo, E. Fukuda, T. Nakayama, M. Nakashima, S. Naito and I. Sekine, Expression of ICAM-1 and acute inflammatory cell infiltration in the early phase of radiation colitis in rats. J. Radiat. Res. 41, 279-291 (2000).
4. C. W. Langberg, M. Hauer-Jensen, C. C. Sung and C. J. M. Kane, Expression of fibrogenic cytokines in rat small intestine after fractionnated irradiation. Radiother. Oncol. 32, 29-36 (1994).
5. C. Linard, A. Ropenga, M. C. Vozenin-Brotons, A. Chapel and D. Mathe, Abdominal irradiation increases inflammatory cytokine expression and activates NF-KB in rat ileal muscularis layer. Am. J. Physiol. Gastrointest. Liver Physiol. 285, G556-G565 (2003).
6. A. V. K. Indaram, V. Visvalingam, M. Locke and S. Bank, Mucosal cytokine production in radiation-induced proctosigmoiditis compared with inflammatory bowel disease. Am. J. Gastroenterol. 95, 1221-1225 (2000).
7. A. Van der Meeren, M. Vandamme, C. Squiban, M. H. Gaugler and M. A. Mouthon, Inflammatory reaction and changes in expression of coagulation proteins on lung endothelial cells after total-body irradiation in mice. Radiat. Res. 160, 637-646 (2003).
8. D. E. Hallahan and S. Virudachalam, Ionizing radiation mediates expression of cell adhesion molecules in distinct histological patterns within the lung. Cancer Res. 57, 2096-2099 (1997).
9. J. Panès, D. C. Anderson, M. Miyasaka and D. N. Granger, Role of leukocyte-endothelial cell adhesion in radiation-induced microvascular dysfunction in rats. Gastroenterology 108, 1761-1769 (1995).
10. M. Molla, M. Gironella, R. Miquel, V. Tovar, P. Engel, A. Biete, J. M. Pique and J. Panes, Relative roles of ICAM-1 and VCAM-1 in the pathogenesis of experimental radiation-induced intestinal inflammation. Int. J. Radiat. Oncol. Biol. Phys. 57, 264-273 (2003).
11. M. Molla, M. Gironella, A. Salas, R. Miquel, S. Perez-del-Pulgar, C. Conill, P. Engel, A. Biete, J. M. Pique and J. Panes, Role of P-selectin in radiation-induced intestinal inflammatory damage. Int. J. Cancer 96, 99-109 (2001).
12. D. E. Hallahan and S. Virudachalam, Accumulation of P-selectin in the lumen of irradiated blood vessels. Radiat. Res. 152, 6-13 (1999).
13. D. L. Garden, J. A. Young and D. N. Granger, Pulmonary microvascular injury after intestinal ischemia-reperfusion: Role of P-selectin. J. Appl. Physiol. 75, 2529-2534 (1993).
14. C. A. Salkowski, G. Detore, A. Francks, M. C. Falk and S. N. Vogel, Pulmonary and hepatic gene expression following cecal ligation and puncture: Morphosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine and neutrophil infiltration. Infect. Immun. 66, 3569-3578 (1998).
15. B. Neumann, N. Zantl, A. Veihelmann, E. K. Pfeffer, C. D. Heidecke and B. Holzmann, Mechanisms of acute inflammatory lung injury induced by abdominal sepsis. Int. Immunol. 11, 217-227 (1999).
16. E. A. Deitch, D. Xu, L. Franko, A. Ayala and I. H. Chaudry, Evidence favoring the role of the gut as a cytokine-generating organ in rats subjected to hemorrhagic shock. Shock 1, 141-145 (1994).
17. W. F. Morgan, Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiat. Res. 159, 581-596 (2003).
18. K. Ohba, K. Omagari, T. Nakamura, N. Ikuno, S. Saeki, I. Matsuo, I. Kinoshita, J. Masuda, H. Hazama and S. Kohno, Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis. Gut 43, 575-577 (1998).
19. K. Camphausen, M. A. Moses, C. Ménard, M. Sproull, W-D. Beecken, J. Folkman and M. S. O'Reilly, Radiation abscopal antitumor effect is mediated through p53. Cancer Res. 63, 1990-1993 (2003).
20. A. Francois, F. Milliat, M. C. Vozenin-Brotons, D. Mathe and N. M. Griffiths, 'In-field' and 'out-of-field' functional impairment during subacute and chronic phases of experimental radiation enteropathy in the rat. Int. J. Radiat. Biol. 79, 437-450 (2003).
21. M. A. Khan, J. Van Dyk, I. W. Yeung and R. P. Hill, Partial volume rat lung irradiation; Assessment of early DNA damage in different lung regions and effect of radical scavengers. Radiother. Oncol. 66, 95-102 (2003).
22. I. Brook and G. D. Ledney, Quinolone therapy in the management of infection after irradiation. Crit. Rev. Microbiol. 18, 235-246 (1992).
23. A. Van der Meeren, M. A. Mouthon, M. H. Gaugler, M. Vandamme and P. Gourmelon, Administration of recombinant human IL11 after supralethal radiation exposure promotes survival in mice: Interactive effect with thrombopoietin. Radiat. Res. 157, 642-649 (2002).
24. C. M. Leutenegger, C. N. Mislin, B. Sigrist, M. U. Ehrengruber, R. Hofmann-Lehmann and H. Lutz, Quantitative real-time PCR for the measurement of feline cytokine mRNA. Vet. Immunol. Immunopathol. 71, 291-305 (1999).
25. V. Eisen and D. I. Walker, Effect of ionizing radiation on prostaglandin-like activity in tissues. Br. J. Pharmacol. 57, 527-532 (1976).
26. T. Kishimoto, The biology of interleukin-6. Blood 74, 1-10 (1989).
27. S. A. Lira, P. Zalamea, J. N. Heinrich, M. E. Fuentes, D. Carrasco, A. C. Lewin, D. S. Barton, S. Durham and R. Bravo, Expression of the chemokine N51/KC in the thymus and epidermis of transgenic mice results in marked infiltration of a single class of inflammatory cells. J. Exp. Med. 180, 2039-2048 (1994).
28. A. Van der Meeren, P. Monti, L. Lebaron-Jacobs, C. Marquette and P. Gourmelon, Characterization of the acute inflammatory response after irradiation in mice and its regulation by interleukin 4. Radiat. Res. 155, 858-865 (2001).
29. M. S. Anscher, F. M. Kong, K. Andrews, R. Clough, L. B. Marks, G. Bentel and R. L. Jirtle, Plasma transforming growth factor beta1 as a predictor of radiation pneumonitis. Int. J. Radiat. Oncol. Biol. Phys. 41, 1029-1035 (1998).
30. U. Hockerfelt, L. Franzen, U. Kjörell and S. Forsgren, Parallel increase in substance P and VIP in rat duodenum in response to irradiation. Peptides 21, 271-281 (2000).
31. H. Seno, M. Sawada, H. Fukuzawa, Y. Morita-Fujisawa, S. Takaishi, H. Hiai and T. Chiba, Involvement of tumor necrosis factor alpha in intestinal epithelial cell proliferation following Paneth cell destruction. Scand. J. Gastroenterol. 37, 154-160 (2002).
32. A. Tailor, A. Tomlinson, A. Salas, J. Panes, D. N. Granger, R. J. Flower and M. Peretti, Dexamethasone inhibition of leucucyte adhesion to rat mesenteric postcapillary venules: Role of intercellular adhesion molecule 1 and KC. Gut 45, 705-712 (1999).
33. F. Song, K. Ito, T. Denning, D. Kuninger, J. Papaconstantinou, W. Gourley, G. Kumpel, E. Balish, J. Hokanson and P. Ernst, Expression of the neutrophil chemokine KC in the colon of mice with enterocolitis and by intestinal epithelial cell lines: Effects of flora and proinflammatory cytokines. J. Immunol. 162, 2275-2280 (1999).
34. A. François, B. Ksas, J. Aigueperse and N. M. Griffiths, The recovery of the neurally evoked secretory response of rat colonic mucosa after irradiation is independent of mast cells. Radiat. Res. 157, 266-274 (2002).
35. S. L. Freeman, M. Hossain and W. K. MacNaughton, Radiation-induced acute intestinal inflammation differs following total-body versus abdominopelvic irradiation in the ferret. Int. J. Radiat. Biol. 77, 389-395 (2001).
36. L. J. Magnotti, D-Z. Xu, Q. Lu and E. A. Deitch, Gut-derived mesenteric lymph: A link between burn and lung injury. Arch. Surg. 134, 1333-1341 (1999).
37. P. Monti, A. Van der Meeren, J. Wysocki and N. M. Griffiths, Abdominal irradiation: A model of severe trauma and inflammation. Shock 21, 154-613A (2004). [abstract]
38. IAEA, The Radiological Accident at the Irradiation Facility in Nesvizh, pp. 46-65. International Atomic Energy Agency, Vienna, 1996.
39. T. Ishii, S. Futami, M. Nishida, T. Suzuki, T. Sakamoto, N. Suzuki and K. Maekawa, Brief note and evaluation of acute-radiation syndrome and treatment of a Tokai-mura criticality accident patient. J. Radiat. Res. (Tokyo) 42 (Suppl.), S167-S182 (2001).
40. IAEA, Diagnosis and Treatment of Radiation Injuries, pp. 41-48. International Atomic Energy Agency, Vienna, 1998.
41. T. Hirama, S. Tanosaki, S. Kandatsu, N. Kuroiwa, T. Kamada, H. Tsuji, S. Yamada, H. Katoh, N. Yamamoto and M. Akashi, Initial medical management of patients severely irradiated in the Tokai-mura criticality accident. Br. J. Radiat. 76, 246-253 (2003).
42. E. A. Deitch, Role of the gut lymphatic system in multiple organ failure. Curr. Opin. Crit. Care 7, 92-98 (2001).
43. S. Kushimoto, K. Okajima, M. Uchiba, K. Murakami, H. Okabe and K. Takatsuki, Pulmonary vascular injury induced by hemorrhagic shock is mediated by P-selectin in rats. Thromb. Res. 82, 97-106 (1996).
44. K. Tsujino, A. Kodama, N. Kanaoka, T. Maruta and M. Kono, Expression of pulmonary mRNA encoding ICAM-1, VCAM-1, and P-selectin following thoracic irradiation in mice. Radiat. Med. 17, 283-287 (1999).
45. C. W. Frevert, S. Huang, H. Danaee, J. D. Paulauskis and L. Kobzik, Functional characterization of the rat chemokine KC and its importance in neutrophil recruitment in a rat model of pulmonary inflammation. J. Immunol. 154, 335-344 (1995).
46. L. Milas and W. R. Hanson, Eicosanoids and radiation. Eur. J. Cancer 31A, 1580-1585 (1995).
47. M. H. Gaugler, C. Squiban, M. A. Mouthon, P. Gourmelon and A. Van der Meeren, Irradiation enhances the support of hematopoietic cell transmigration and differentiation by endothelial cells. Br. J. Haematol. 113, 940-950 (2001).
48. S. Quarmby, R. D. Hunter and S. Kumar, Irradiation induced expression of CD31, ICAM-1 and VCAM-1 in human microvascular endothelial cells. Anticancer Res. 20, 3375-3381 (2000).
49. S. M. Watt, S. E. Gschmeissner and P. A. Bates, PECAM-1: Its expression and function as a cell adhesion molecule on hematopoietic and endothelial cells. Leukemia Lymphoma 17, 229-244 (1995).