-
1
-
-
0029815716
-
Gene-directed enzyme prodrug therapy with a mustard prodrug/ carboxypeptidase G2 combination
-
Marais, R., Spooner, R. A., Light, Y., Martin, J., and Springer, C. J. (1996) Gene-directed enzyme prodrug therapy with a mustard prodrug/ carboxypeptidase G2 combination. Cancer Res. 56, 4735-4742.
-
(1996)
Cancer Res.
, vol.56
, pp. 4735-4742
-
-
Marais, R.1
Spooner, R.A.2
Light, Y.3
Martin, J.4
Springer, C.J.5
-
2
-
-
0029609610
-
Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954
-
Bridgewater, G., Springer, C. J., Knox, R., Minton, N., Michael, P., and Collins, M. (1995) Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954. Eur. J. Cancer 31A, 2362-2370.
-
(1995)
Eur. J. Cancer
, vol.31 A
, pp. 2362-2370
-
-
Bridgewater, G.1
Springer, C.J.2
Knox, R.3
Minton, N.4
Michael, P.5
Collins, M.6
-
3
-
-
0029637158
-
VDEPT; an enzyme/prodrug gene therapy approach for the treatment of metastatic colorectal cancer
-
Huber, B. E., Richards, C. A., and Austin, E. A. (1995) VDEPT; an enzyme/prodrug gene therapy approach for the treatment of metastatic colorectal cancer. Adv. Drug Delivery Rev. 17, 279-292.
-
(1995)
Adv. Drug Delivery Rev.
, vol.17
, pp. 279-292
-
-
Huber, B.E.1
Richards, C.A.2
Austin, E.A.3
-
4
-
-
0035038479
-
Genetic prodrug activation therapy (GPAT) in two rat prostate models generates an immune bystander effect and can be monitored by magnetic resonance techniques
-
Eaton, J. L., Perry, M. J. A., Todryk, S. M., et al. (2001) Genetic prodrug activation therapy (GPAT) in two rat prostate models generates an immune bystander effect and can be monitored by magnetic resonance techniques. Gene Ther. 8, 557-567.
-
(2001)
Gene Ther.
, vol.8
, pp. 557-567
-
-
Eaton, J.L.1
Perry, M.J.A.2
Todryk, S.M.3
-
5
-
-
0034022622
-
Gene-delivery from replication-selective viruses: Arming guided missiles in the war against cancer
-
Hermiston, T. (2000) Gene-delivery from replication-selective viruses: arming guided missiles in the war against cancer. J. Clin. Invest. 105, 1169-1172.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1169-1172
-
-
Hermiston, T.1
-
6
-
-
0031025998
-
Gene therapy for cancer: What have we done and where are we going?
-
Roth, J. A. and Cristiano, R. G. (1997) Gene therapy for cancer: what have we done and where are we going? J. Natl. Cancer Inst. 89, 21-30.
-
(1997)
J. Natl. Cancer Inst.
, vol.89
, pp. 21-30
-
-
Roth, J.A.1
Cristiano, R.G.2
-
7
-
-
0031983448
-
Gene-directed enzyme prodrug therapy
-
Niculescu-Duvaz, I., Spooner, R., Marais, R., and Springer, C. J. (1998) Gene-directed enzyme prodrug therapy. Bioconj. Chem. 9, 4-22.
-
(1998)
Bioconj. Chem.
, vol.9
, pp. 4-22
-
-
Niculescu-Duvaz, I.1
Spooner, R.2
Marais, R.3
Springer, C.J.4
-
8
-
-
0032879929
-
Patent property of prodrug involving gene therapy (1996-1999)
-
Springer, C. J. and Niculescu-Duvaz, I. (1999) Patent property of prodrug involving gene therapy (1996-1999). Exp. Opin. Ther. Patents 9, 1381-1388.
-
(1999)
Exp. Opin. Ther. Patents
, vol.9
, pp. 1381-1388
-
-
Springer, C.J.1
Niculescu-Duvaz, I.2
-
9
-
-
0031771465
-
Improving adenoviral vectors for cancer gene therapy
-
Bilbao, G., Contreras, J. L., Gómez-Navarro, J., and Curiel, D. T. (1998) Improving adenoviral vectors for cancer gene therapy. Tumor Target. 3, 59-79.
-
(1998)
Tumor Target.
, vol.3
, pp. 59-79
-
-
Bilbao, G.1
Contreras, J.L.2
Gómez-Navarro, J.3
Curiel, D.T.4
-
10
-
-
0032535405
-
Adeno-associated virus-mediated delivery of antiangiogenic factors as an antitumor stratergy
-
Nguyen, J. T., Wu, P., Clouse, M. E., Hlatky, L., and Terwilliger, E. F. (1998) Adeno-associated virus-mediated delivery of antiangiogenic factors as an antitumor stratergy. Cancer Res. 58, 5673-5677.
-
(1998)
Cancer Res.
, vol.58
, pp. 5673-5677
-
-
Nguyen, J.T.1
Wu, P.2
Clouse, M.E.3
Hlatky, L.4
Terwilliger, E.F.5
-
11
-
-
0031770243
-
Viral vectors for gene therapy
-
Robbins, P. D. and Ghivizzani, S. C. (1998) Viral vectors for gene therapy. Pharm. Ther. 80, 35-47.
-
(1998)
Pharm. Ther.
, vol.80
, pp. 35-47
-
-
Robbins, P.D.1
Ghivizzani, S.C.2
-
12
-
-
0033088695
-
Development and application of adenoviral vectors for gene therapy of cancer
-
Zhang, W. W. (1999) Development and application of adenoviral vectors for gene therapy of cancer. Cancer Gene Ther. 7, 113-138.
-
(1999)
Cancer Gene Ther.
, vol.7
, pp. 113-138
-
-
Zhang, W.W.1
-
13
-
-
0033845884
-
Progress in cancer gene therapy
-
Curiel, D. T., Gerritsen, W. R. and Krul, M. R. (2000) Progress in cancer gene therapy. Cancer Gene Ther. 7, 1197-1199.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1197-1199
-
-
Curiel, D.T.1
Gerritsen, W.R.2
Krul, M.R.3
-
14
-
-
0034490393
-
Toward the optimal vector for prostate cancer gene therapy; a CaPCURE meeting report
-
Roth, M. G. and Curiel, D. T. (2000) Toward the optimal vector for prostate cancer gene therapy; a CaPCURE meeting report. Cancer Gene Ther. 7, 1507-1510.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1507-1510
-
-
Roth, M.G.1
Curiel, D.T.2
-
15
-
-
0035134629
-
Clinical research results with di 1520 (ONYX-015), a replication selective adenovirus for the treatment of cancer: What have we learned?
-
Kirn, D. (2001) Clinical research results with dI 1520 (ONYX-015), a replication selective adenovirus for the treatment of cancer: what have we learned? Gene Ther. 8, 89-98.
-
(2001)
Gene Ther.
, vol.8
, pp. 89-98
-
-
Kirn, D.1
-
16
-
-
0032479769
-
Cationic liposomes for gene therapy
-
Miller, A. D. (1998) Cationic liposomes for gene therapy. Angew. Chem. Int. Ed. 37, 1768-1785.
-
(1998)
Angew. Chem. Int. Ed.
, vol.37
, pp. 1768-1785
-
-
Miller, A.D.1
-
17
-
-
0034997403
-
Non-viral vectors in cancer gene therapy: Principles and progress
-
Schatzlein, A. G. (2001) Non-viral vectors in cancer gene therapy: principles and progress. Anti-Cancer Drug Des. 12, 275-304.
-
(2001)
Anti-Cancer Drug Des.
, vol.12
, pp. 275-304
-
-
Schatzlein, A.G.1
-
18
-
-
0034105702
-
Prodrug-activating systems in suicide gene therapy
-
Springer, C. J. and Niculescu-Duvaz, I. (2000) Prodrug-activating systems in suicide gene therapy. J. Clin. Investig. 105, 1161-1167.
-
(2000)
J. Clin. Investig.
, vol.105
, pp. 1161-1167
-
-
Springer, C.J.1
Niculescu-Duvaz, I.2
-
19
-
-
0032966050
-
Improving enzymes for gene therapy
-
Encell, L. P., Landis, D. M. and Loeb, L. A. (1999) Improving enzymes for gene therapy. Nature Biotechnol. 17, 143-147.
-
(1999)
Nature Biotechnol.
, vol.17
, pp. 143-147
-
-
Encell, L.P.1
Landis, D.M.2
Loeb, L.A.3
-
20
-
-
0033900009
-
Bystander effect in herpes simplex virus-thymidine kinase/ganciclovir cancer gene therapy: Role of gap-junctional intercellular communications
-
Mesnil, M. and Yamasachi, H. (2000) Bystander effect in herpes simplex virus-thymidine kinase/ganciclovir cancer gene therapy: role of gap-junctional intercellular communications. Cancer Res. 60, 3989-3999.
-
(2000)
Cancer Res.
, vol.60
, pp. 3989-3999
-
-
Mesnil, M.1
Yamasachi, H.2
-
21
-
-
0031956262
-
The design of selectively-activated anti-cancer prodrugs for use in antibody-directed and gene-directed enzyme prodrugs therapies
-
Denny, W. A. and Wilson, W. R. (1998) The design of selectively-activated anti-cancer prodrugs for use in antibody-directed and gene-directed enzyme prodrugs therapies. J. Pharm. Pharmacol. 50, 387-394.
-
(1998)
J. Pharm. Pharmacol.
, vol.50
, pp. 387-394
-
-
Denny, W.A.1
Wilson, W.R.2
-
22
-
-
0033502650
-
Prodrugs for antibody- and gene-directed enzyme prodrug therapies (ADEPT and GDEPT)
-
Niculescu-Duvaz, I., Friedlos, F., Niculescu-Duvaz, D., Davies, L., and Springer, C. J. (1999) Prodrugs for antibody- and gene-directed enzyme prodrug therapies (ADEPT and GDEPT). Anticancer Drug Des. 14, 517-538.
-
(1999)
Anticancer Drug Des.
, vol.14
, pp. 517-538
-
-
Niculescu-Duvaz, I.1
Friedlos, F.2
Niculescu-Duvaz, D.3
Davies, L.4
Springer, C.J.5
-
23
-
-
2342467196
-
Gene-directed enzyme prodrug therapy
-
(Baguley, B., ed.). Academic, New York
-
Springer, C. J. and Niculescu-Duvaz, I. (2002) Gene-directed enzyme prodrug therapy. In: Anticancer Drug Development (Baguley, B., ed.). Academic, New York, pp. 137-135.
-
(2002)
Anticancer Drug Development
, pp. 137-1135
-
-
Springer, C.J.1
Niculescu-Duvaz, I.2
-
24
-
-
0031437780
-
A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy
-
Marais, R., Spooner, R. A., Stribbling, S. M., Light, Y., Martin, J., and Springer, C. J. (1997) A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy. Nature Biotechnol. 15, 1373-1377.
-
(1997)
Nature Biotechnol.
, vol.15
, pp. 1373-1377
-
-
Marais, R.1
Spooner, R.A.2
Stribbling, S.M.3
Light, Y.4
Martin, J.5
Springer, C.J.6
-
25
-
-
0035100085
-
Human prostate carcinoma cells as target for herpes simplex virus thymidine kinase-mediated suicide gene therapy
-
Loimas, S., Toppinen, M.-R., Visakorpi, T., Janne, J., and Wahlfors, D. (2001) Human prostate carcinoma cells as target for herpes simplex virus thymidine kinase-mediated suicide gene therapy. Cancer Gene Ther. 8, 137-144.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 137-144
-
-
Loimas, S.1
Toppinen, M.-R.2
Visakorpi, T.3
Janne, J.4
Wahlfors, D.5
-
26
-
-
0034490547
-
Combined suicide and granulocyte-macrophage colony-stimulating factor gene therapy induces complete tumor regression and generates antitumor immunity
-
Jones, R. K., Pope, I. M., Kinsella, A. R., Watson, A. J. M., and Christmas, S. E. (2000) Combined suicide and granulocyte-macrophage colony-stimulating factor gene therapy induces complete tumor regression and generates antitumor immunity. Cancer Gene Ther. 7, 1519-1528.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1519-1528
-
-
Jones, R.K.1
Pope, I.M.2
Kinsella, A.R.3
Watson, A.J.M.4
Christmas, S.E.5
-
27
-
-
0034072458
-
Bystander-mediated regression of osteosarcoma via retroviral transfer of the herpes simplex virus thymidine kinase and human interleukin-2 genes
-
Walling, H. W., Swarthout, G. T., and Culver, K. W. (2000) Bystander-mediated regression of osteosarcoma via retroviral transfer of the herpes simplex virus thymidine kinase and human interleukin-2 genes. Cancer Gene Ther. 7, 187-196.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 187-196
-
-
Walling, H.W.1
Swarthout, G.T.2
Culver, K.W.3
-
28
-
-
0033920755
-
Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir
-
Howard, B. D., Boenicke, L., Schniewind, B., Henne-Bruns, D., and Kalthoff, H. (2000) Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir. Cancer Gene Ther. 7, 927-938.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 927-938
-
-
Howard, B.D.1
Boenicke, L.2
Schniewind, B.3
Henne-Bruns, D.4
Kalthoff, H.5
-
29
-
-
0034128036
-
Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: Effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reac­tions
-
Sandmair, A.-M., Turunen, M., Tyynela, K., et al. (2000) Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reac­tions. Cancer Gene Ther. 7, 413-421.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 413-421
-
-
Sandmair, A.-M.1
Turunen, M.2
Tyynela, K.3
-
30
-
-
0033980574
-
Purified herpes simplex thymidine kinase retroviral particles. II. Influence of clinical parameters and bystander killing mechanisms
-
Kruse, C. A., Lamb, C., Hogan, S., Russell Smiley, W., Kleinschmidt-DeMasters, B., and Burrows, F. G. (2000) Purified herpes simplex thymidine kinase retroviral particles. II. Influence of clinical parameters and bystander killing mechanisms. Cancer Gene Ther. 7, 118-127.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 118-127
-
-
Kruse, C.A.1
Lamb, C.2
Hogan, S.3
Russell Smiley, W.4
Kleinschmidt-DeMasters, B.5
Burrows, F.G.6
-
31
-
-
0034922609
-
E-5-(2-bromovinyl)-2′-deoxyuridine potentiates ganciclovir-mediated cytotoxicity on herpes simplex virus-thymidine kinase-expressing cells
-
Hamel, W., Zirkel, D., Mehdorn, H. M., Westphal, M., and Israel, M. A. (2001) E-5-(2-bromovinyl)-2′-deoxyuridine potentiates ganciclovir-mediated cytotoxicity on herpes simplex virus-thymidine kinase-expressing cells. Cancer Gene Ther. 8, 388-396.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 388-396
-
-
Hamel, W.1
Zirkel, D.2
Mehdorn, H.M.3
Westphal, M.4
Israel, M.A.5
-
32
-
-
0034033272
-
Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2′-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-β-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase
-
Grignet-Debrus, C., Cool, V., Baudson, N., et al. (2000) Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2′- deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1- β-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase. Cancer Gene Ther. 7, 215-223.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 215-223
-
-
Grignet-Debrus, C.1
Cool, V.2
Baudson, N.3
-
33
-
-
0034660858
-
In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene
-
Erbs, P., Regulier, E., Kintz, J., et al. (2000) In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene. Cancer Res. 60, 3813-3822.
-
(2000)
Cancer Res.
, vol.60
, pp. 3813-3822
-
-
Erbs, P.1
Regulier, E.2
Kintz, J.3
-
34
-
-
0033950759
-
Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis
-
Bentires-Alj, M., Helin, A.-C., Lechanteur, C., et al. (2000) Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis. Cancer Gene Ther. 7, 20-26.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 20-26
-
-
Bentires-Alj, M.1
Helin, A.-C.2
Lechanteur, C.3
-
35
-
-
0035399802
-
Appropriate subcellular location of prodrug-activating enzymes has important consequences for suicide gene therapy
-
Spooner, R. A., Maycroft, K. A., Paterson, H., Friedlos, F., Springer, C. J., and Marais, R. (2001) Appropriate subcellular location of prodrug-activating enzymes has important consequences for suicide gene therapy. Int. J. Cancer 93, 123-130.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 123-130
-
-
Spooner, R.A.1
Maycroft, K.A.2
Paterson, H.3
Friedlos, F.4
Springer, C.J.5
Marais, R.6
-
36
-
-
0033981131
-
The nitroreductase/CB1954 combination in Epstein-Barr virus-positive B cell lines: Induction of bystander killing in vitro and in vivo
-
Westphal, E.-M., Ge, J., Catchpole, J. R., Ford, M., and Kennedy, S. C. (2000) The nitroreductase/CB1954 combination in Epstein-Barr virus-positive B cell lines: induction of bystander killing in vitro and in vivo. Cancer Gene Ther. 7, 97-106.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 97-106
-
-
Westphal, E.-M.1
Ge, J.2
Catchpole, J.R.3
Ford, M.4
Kennedy, S.C.5
-
37
-
-
0034032741
-
The potential of acetaminophen as a prodrug in gene-directed enzyme therapy
-
Tatcher, N. J., Edwards, R. J., Lemoine, N. R., Doehmer, J., and Davies, D. S. (2000) The potential of acetaminophen as a prodrug in gene-directed enzyme therapy. Cancer Gene Ther. 7, 521-525.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 521-525
-
-
Tatcher, N.J.1
Edwards, R.J.2
Lemoine, N.R.3
Doehmer, J.4
Davies, D.S.5
-
38
-
-
0034947012
-
Cell surface display of a lysosomal enzyme for extra-cellular gene-directed enzyme prodrug therapy
-
Heine, D., Muller, R., and Brusselbach, S. (2001) Cell surface display of a lysosomal enzyme for extra-cellular gene-directed enzyme prodrug therapy. Gene Ther. 8, 1005-1010.
-
(2001)
Gene Ther.
, vol.8
, pp. 1005-1010
-
-
Heine, D.1
Muller, R.2
Brusselbach, S.3
-
39
-
-
0033961881
-
Expression of endogenously activated secreted or cell surface carboxypeptidase A sensitizes tumor cells to methotrexate-_-peptide prodrugs
-
Hamstra, D. A., Page, M., Maybaum, J., and Rehemtulla, A. (2000) Expression of endogenously activated secreted or cell surface carboxypeptidase A sensitizes tumor cells to methotrexate-_-peptide prodrugs. Cancer Res. 60, 657-665.
-
(2000)
Cancer Res.
, vol.60
, pp. 657-665
-
-
Hamstra, D.A.1
Page, M.2
Maybaum, J.3
Rehemtulla, A.4
-
40
-
-
0034688260
-
Regressions of established breast cancer xenografts by carboxypeptidase G2 suicide gene therapy and the prodrug CMDA are due to a bystander effect
-
Stribbling, S. M., Friedlos, F., Martin, J., et al. (2000) Regressions of established breast cancer xenografts by carboxypeptidase G2 suicide gene therapy and the prodrug CMDA are due to a bystander effect. Hum. Gene Ther. 11, 285-292.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 285-292
-
-
Stribbling, S.M.1
Friedlos, F.2
Martin, J.3
-
41
-
-
0033664464
-
Development of a novel enzyme/prodrug combination for gene therapy of cancer: Horseradish per-oxidase/indole-3-acetic acid
-
Greco, O., Folkes, L. K., Wardman, P., Tozer, G. M., and Dachs, G. U. (2000) Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish per-oxidase/indole-3-acetic acid. Cancer Gene Ther. 7, 1414-1420.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1414-1420
-
-
Greco, O.1
Folkes, L.K.2
Wardman, P.3
Tozer, G.M.4
Dachs, G.U.5
-
42
-
-
0034541169
-
Tyrosinase mutants are capable of prodrug activation in transfected non-melanotic cells
-
Simonova, M., Wall, A., Weissleder, R., and Bogdanov, A. (2000). Tyrosinase mutants are capable of prodrug activation in transfected non-melanotic cells. Cancer Res. 60, 6656-6662.
-
(2000)
Cancer Res.
, vol.60
, pp. 6656-6662
-
-
Simonova, M.1
Wall, A.2
Weissleder, R.3
Bogdanov, A.4
-
43
-
-
0034087221
-
Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5-fluorouracil and induces protective immunity
-
Kawamura, K., Tasaki, K., Hamada, H., Takenaga, K., Sakiyama, S., and Tagawa, M. (2000) Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5-fluorouracil and induces protective immunity. Cancer Gene Ther. 7, 637-643.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 637-643
-
-
Kawamura, K.1
Tasaki, K.2
Hamada, H.3
Takenaga, K.4
Sakiyama, S.5
Tagawa, M.6
-
44
-
-
0035875466
-
Fluoropyrimidine sensitivity of human MCF-7 breast cancer cells stably transfected with human uridine phosphorylase
-
Cuq, P., Rouquet, C., Evrard, A., Ciccolini, J., Vian, L., and Cano, J.-P. (2001) Fluoropyrimidine sensitivity of human MCF-7 breast cancer cells stably transfected with human uridine phosphorylase. Br. J. Cancer 84, 1677-1680.
-
(2001)
Br. J. Cancer
, vol.84
, pp. 1677-1680
-
-
Cuq, P.1
Rouquet, C.2
Evrard, A.3
Ciccolini, J.4
Vian, L.5
Cano, J.-P.6
-
45
-
-
0033993506
-
Secreted human _-glucuronidase: A novel tool for gene-directed enzyme prodrug therapy
-
Weyel, D., Sedlacek, H. H., Muller, R., and Brusselbach, S. (2000) Secreted human _-glucuronidase: a novel tool for gene-directed enzyme prodrug therapy. Gene Ther. 7, 224-231.
-
(2000)
Gene Ther.
, vol.7
, pp. 224-231
-
-
Weyel, D.1
Sedlacek, H.H.2
Muller, R.3
Brusselbach, S.4
-
46
-
-
0029883624
-
Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy
-
Black, M. E., Newcomb, T. G., Wilson, H. M., and Loeb, L. A. (1996) Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy. Proc. Natl. Acad. Sci. USA 93, 3525-3529.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3525-3529
-
-
Black, M.E.1
Newcomb, T.G.2
Wilson, H.M.3
Loeb, L.A.4
-
47
-
-
0035300565
-
Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing
-
Black, M., Kokoris, M. S., and Sabo, P. (2001) Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing. Cancer Res. 61, 3022-3026.
-
(2001)
Cancer Res.
, vol.61
, pp. 3022-3026
-
-
Black, M.1
Kokoris, M.S.2
Sabo, P.3
-
48
-
-
26244435639
-
-
Enzymes Combinations for Destroying Proliferative Cells, US Patent W09735024, Rhone-Poulenc Roerer, p. 1-61
-
Blanche, F., Cameron, B., Couder, M., and Crouzet, J. (1997). Enzymes Combinations for Destroying Proliferative Cells, US Patent W09735024, Rhone-Poulenc Roerer, p. 1-61.
-
(1997)
-
-
Blanche, F.1
Cameron, B.2
Couder, M.3
Crouzet, J.4
-
49
-
-
0030810198
-
Potentiation of cytochrome P450/cyclo-phosphamide-based cancer gene therapy by coexpression of the P450 reductase gene
-
Chen, L., Yu, L. J., and Waxman, D. J. (1997) Potentiation of cytochrome P450/cyclo-phosphamide-based cancer gene therapy by coexpression of the P450 reductase gene. Cancer Res. 57, 4830-4837.
-
(1997)
Cancer Res.
, vol.57
, pp. 4830-4837
-
-
Chen, L.1
Yu, L.J.2
Waxman, D.J.3
-
50
-
-
0040717056
-
Ganciclovir-mediated cell killing and bystander effect is enhanced in cells with two copies of the herpes simplex virus thymidine kinase
-
Kim, Y. G., Bi, W., Feliciano, E. S., Drake, R. R., and Stambrook, P. J. (2000) Ganciclovir-mediated cell killing and bystander effect is enhanced in cells with two copies of the herpes simplex virus thymidine kinase. Cancer Gene Ther. 7, 240-246.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 240-246
-
-
Kim, Y.G.1
Bi, W.2
Feliciano, E.S.3
Drake, R.R.4
Stambrook, P.J.5
-
51
-
-
0034115137
-
Combined chemotherapy of murine mammary tumors by local activation of the prodrug ifosfamide and 5-fluorocytosine
-
Kammertoens, T., Gelbmann, W., Karle, P., et al. (2000) Combined chemotherapy of murine mammary tumors by local activation of the prodrug ifosfamide and 5-fluorocytosine. Cancer Gene Ther. 7, 629-636.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 629-636
-
-
Kammertoens, T.1
Gelbmann, W.2
Karle, P.3
-
52
-
-
0033984339
-
Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization
-
Rogulski, K. R., Wing, M. S., Paielli, D. L., Gilbert, J. D., Kim J. H., and Freytag, S. O. (2000) Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization. Hum. Gene Ther. 11, 67-76.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 67-76
-
-
Rogulski, K.R.1
Wing, M.S.2
Paielli, D.L.3
Gilbert, J.D.4
Kim, J.H.5
Freytag, S.O.6
-
53
-
-
0035076462
-
Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine
-
Toda, M., Martuza, R. L., and Rabkin, S. D. (2001) Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine. Gene Ther. 8, 332-339.
-
(2001)
Gene Ther.
, vol.8
, pp. 332-339
-
-
Toda, M.1
Martuza, R.L.2
Rabkin, S.D.3
-
54
-
-
0034034314
-
Use of a herpes thymidine kinase/neomycin phosphotransferase chimeric gene for metabolic suicide gene therapy
-
Candotti, F., Agbaria, R., Mullen, C. A., et al. (2000) Use of a herpes thymidine kinase/neomycin phosphotransferase chimeric gene for metabolic suicide gene therapy. Cancer Gene Ther. 7, 574-580.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 574-580
-
-
Candotti, F.1
Agbaria, R.2
Mullen, C.A.3
-
55
-
-
0033974798
-
Comparison of the genotoxic and apoptosis-inducing properties of ganciclovir and penciclovir in Chinese hamster ovary cells transfected with the thymidine kinase gene of herpes simplex virus-1: Implication for gene therapeutic approaches
-
Thust, R., Tomicic, M., Klocking, R., Voutilainen, N., Wutzler, P., and Kaina, B. (2000) Comparison of the genotoxic and apoptosis-inducing properties of ganciclovir and penciclovir in Chinese hamster ovary cells transfected with the thymidine kinase gene of herpes simplex virus-1: implication for gene therapeutic approaches. Cancer Gene Ther. 7, 107-117.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 107-117
-
-
Thust, R.1
Tomicic, M.2
Klocking, R.3
Voutilainen, N.4
Wutzler, P.5
Kaina, B.6
-
56
-
-
0034039073
-
Avoidance of bone marrow suppression using A-5021 as a nucleoside analog for retrovirus-mediated herpes simplex virus type I thymidine kinase gene therapy
-
Hasegawa, Y., Nishiyama, Y., Imaizumi, K., et al. (2000) Avoidance of bone marrow suppression using A-5021 as a nucleoside analog for retrovirus-mediated herpes simplex virus type I thymidine kinase gene therapy. Cancer Gene Ther. 7, 557-562.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 557-562
-
-
Hasegawa, Y.1
Nishiyama, Y.2
Imaizumi, K.3
-
57
-
-
0033951472
-
Potentiation of ganciclovir toxicity in the herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin
-
Hayashi, K., Hayashi, T., Sun, H.-D., and Takeda, I. (2000) Potentiation of ganciclovir toxicity in the herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin. Cancer Gene Ther. 7, 45-42.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 45-142
-
-
Hayashi, K.1
Hayashi, T.2
Sun, H.-D.3
Takeda, I.4
-
58
-
-
0034085228
-
Two-drug combinations that increase apoptosis and modulate Bak and Bcl-XL expression in human colon tumor cell lines transduced with herpes simplex virus thymidine kinase
-
McMasters, R. A., Wilbert, T. N., Jones, K. E., et al. (2000) Two-drug combinations that increase apoptosis and modulate Bak and Bcl-XL expression in human colon tumor cell lines transduced with herpes simplex virus thymidine kinase. Cancer Gene Ther. 7, 563-573.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 563-573
-
-
McMasters, R.A.1
Wilbert, T.N.2
Jones, K.E.3
-
59
-
-
0032169967
-
Superior cytotoxicity with gancyclovir compared with acyclovir and 1-β-D-arabinofuranosylthymine in herpes simplex virus-thymidine kinase-expressing-cells: A novel paradigm for cell killing
-
Rubsam, L. Z., Davidson, L., and Shewach, D. S. (1998) Superior cytotoxicity with gancyclovir compared with acyclovir and 1-β-D- arabinofuranosylthymine in herpes simplex virus-thymidine kinase-expressing- cells: a novel paradigm for cell killing. Cancer Res. 58, 3873-3882.
-
(1998)
Cancer Res.
, vol.58
, pp. 3873-3882
-
-
Rubsam, L.Z.1
Davidson, L.2
Shewach, D.S.3
-
60
-
-
0034654516
-
Synergistic enhancement of herpes simplex virus thymidine kinase/ganciclovir mediated cytotoxicity by hydroxyurea
-
Boucher, P. D., Ostruszka, L. J., and Shewach, D. S. (2000) Synergistic enhancement of herpes simplex virus thymidine kinase/ganciclovir mediated cytotoxicity by hydroxyurea. Cancer Res. 60, 1631-1636.
-
(2000)
Cancer Res.
, vol.60
, pp. 1631-1636
-
-
Boucher, P.D.1
Ostruszka, L.J.2
Shewach, D.S.3
-
61
-
-
0033943812
-
Impact of liver P450 reductase suppression on cyclophosphamide activation, pharmacokinetics and antitumoral activity in a cytochrom P450-based cancer gene therapy model
-
Huang, Z., Raychowdhury, K., and Waxman, D. J. (2000) Impact of liver P450 reductase suppression on cyclophosphamide activation, pharmacokinetics and antitumoral activity in a cytochrom P450-based cancer gene therapy model. Cancer Gene Ther. 7, 1034-1042.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1034-1042
-
-
Huang, Z.1
Raychowdhury, K.2
Waxman, D.J.3
-
62
-
-
0034660849
-
Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy
-
Jounaidi, Y. and Waxman, D. J. (2000) Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy. Cancer Res. 60, 3761-3769.
-
(2000)
Cancer Res.
, vol.60
, pp. 3761-3769
-
-
Jounaidi, Y.1
Waxman, D.J.2
-
63
-
-
0035138403
-
Usefulness of repeated intratumoral gene transfer using hemagglutinating virus of Japan-liposome method for cytosine deaminase suicide gene therapy
-
Kanyama, H., Tomita, N., Yamano, T., et al. (2001) Usefulness of repeated intratumoral gene transfer using hemagglutinating virus of Japan-liposome method for cytosine deaminase suicide gene therapy. Cancer Res. 61, 14-18.
-
(2001)
Cancer Res.
, vol.61
, pp. 14-18
-
-
Kanyama, H.1
Tomita, N.2
Yamano, T.3
-
64
-
-
0035360868
-
Frequent, moderate dose cyclophosphamide administration improves the efficacy of cytochrome P-450/cytochrome P-450 reductase based cancer gene therapy
-
Jounaidi, Y. and Waxman, D. J. (2001) Frequent, moderate dose cyclophosphamide administration improves the efficacy of cytochrome P-450/cytochrome P-450 reductase based cancer gene therapy. Cancer Res. 61, 4437-4444.
-
(2001)
Cancer Res.
, vol.61
, pp. 4437-4444
-
-
Jounaidi, Y.1
Waxman, D.J.2
-
65
-
-
0034077052
-
Radiosensitization of rat glioma with bromodeoxycytidine and adenovirus expressing herpes simplex virus-thymidine kinase delivered by slow, rate-controlled positive pressure infusion
-
Brust, D., Feden, J., Farnsworth, J., Amir, C., Broaddus, W. C., and Valerie, K. (2000) Radiosensitization of rat glioma with bromodeoxycytidine and adenovirus expressing herpes simplex virus-thymidine kinase delivered by slow, rate-controlled positive pressure infusion. Cancer Gene Ther. 7, 778-788.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 778-788
-
-
Brust, D.1
Feden, J.2
Farnsworth, J.3
Amir, C.4
Broaddus, W.C.5
Valerie, K.6
-
66
-
-
0033935125
-
Improved radiosensitization of rat glioma cells with adenovirus-expressed mutant herpes simplex virus-thymidine kinase in combination with acyclovir
-
Valerie, K., Brust, D., Farnsworth, J., et al. (2000) Improved radiosensitization of rat glioma cells with adenovirus-expressed mutant herpes simplex virus-thymidine kinase in combination with acyclovir. Cancer Gene Ther. 7, 879-884.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 879-884
-
-
Valerie, K.1
Brust, D.2
Farnsworth, J.3
-
67
-
-
0035121644
-
Substantially improved in vivo radiosensitization of rat glioma with mutant HSV-TK and acyclovir
-
Valerie, K., Hawkins, W., Farnsworth, J., et al. (2001) Substantially improved in vivo radiosensitization of rat glioma with mutant HSV-TK and acyclovir. Cancer Gene Ther. 8, 3-8.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 3-8
-
-
Valerie, K.1
Hawkins, W.2
Farnsworth, J.3
-
68
-
-
2442745332
-
Regression of hepatocelluar carcinoma in vitro and in vivo by radiosensitising suicide gene therapy under the inducible and spatial control of radiation
-
Kawashita, Y., Ohtsuru, A., Kaneda, Y., et al. (1999) Regression of hepatocelluar carcinoma in vitro and in vivo by radiosensitising suicide gene therapy under the inducible and spatial control of radiation. Hum. Gene Ther. 10, 1509-1519.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1509-1519
-
-
Kawashita, Y.1
Ohtsuru, A.2
Kaneda, Y.3
-
69
-
-
0035013495
-
Increasing specificity of anti-tumour therapy: Cytotoxic proteins delivery by non-pathogenic Clostridia under regulation of radio-induced promoter
-
Nuyts, S., Theys, J., Landuyt, W., Van Mellaert, L., Lambin, P., and Anne, J. (2001) Increasing specificity of anti-tumour therapy: cytotoxic proteins delivery by non-pathogenic Clostridia under regulation of radio-induced promoter. Anticancer Res. 21, 857-862.
-
(2001)
Anticancer Res.
, vol.21
, pp. 857-862
-
-
Nuyts, S.1
Theys, J.2
Landuyt, W.3
Van Mellaert, L.4
Lambin, P.5
Anne, J.6
-
70
-
-
0035014279
-
The use of radiation-induced bacterial promoters in anaerobic-conditions: A means to control gene expression in Clostridium-mediated gene therapy
-
Nuyts, S., Van Mellaert, L., Theys, J., Landuyt, W., Lambin, P., and Anne, J. (2001) The use of radiation-induced bacterial promoters in anaerobic-conditions: a means to control gene expression in Clostridium-mediated gene therapy. Radiat. Res. 155, 716-723.
-
(2001)
Radiat. Res.
, vol.155
, pp. 716-723
-
-
Nuyts, S.1
Van Mellaert, L.2
Theys, J.3
Landuyt, W.4
Lambin, P.5
Anne, J.6
-
71
-
-
0034102736
-
Enhanced green fluorescent proteinfusion proteins of herpes simplex virus type 1 thymidine kinase and cytochrome P450 4B1: Applications for prodrug-activating gene therapy
-
Steffens, S., Frank, S., Fisher, U., et al. (2000) Enhanced green fluorescent proteinfusion proteins of herpes simplex virus type 1 thymidine kinase and cytochrome P450 4B1: applications for prodrug-activating gene therapy. Cancer Gene Ther. 7, 806-812.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 806-812
-
-
Steffens, S.1
Frank, S.2
Fisher, U.3
-
72
-
-
9544242826
-
Noninvasive imaging of herpes simplex virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy
-
Tjuvajev, J.G., Finn, R., Watanabe, K., et al. (1996) Noninvasive imaging of herpes simplex virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res. 56, 4087-4095.
-
(1996)
Cancer Res.
, vol.56
, pp. 4087-4095
-
-
Tjuvajev, J.G.1
Finn, R.2
Watanabe, K.3
-
73
-
-
17144471900
-
Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography
-
Tjuvajev, J.G., Avril, N., Oku, T., et al. (1998) Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res. 58, 4333-4341.
-
(1998)
Cancer Res.
, vol.58
, pp. 4333-4341
-
-
Tjuvajev, J.G.1
Avril, N.2
Oku, T.3
-
74
-
-
0034785946
-
Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors
-
Yagoubi, S. S., Wu, L., Liang, Q., et al. (2001) Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors. Gene Ther. 8, 1072-1080.
-
(2001)
Gene Ther.
, vol.8
, pp. 1072-1080
-
-
Yagoubi, S.S.1
Wu, L.2
Liang, Q.3
-
75
-
-
0035024462
-
124/ 125I]FIAU for imaging herpes simplex virus type 1 thymidine kinase gene expression
-
124/ 125I]FIAU for imaging herpes simplex virus type 1 thymidine kinase gene expression. Eur. J. Nucl. Med 28, 721-729.
-
(2001)
Eur. J. Nucl. Med.
, vol.28
, pp. 721-729
-
-
Brust, P.1
Haubner, R.2
Friedrich, A.3
-
76
-
-
0028108469
-
Metabolism of 5-fluorocytidine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
-
Huber, B. F., Austin, E. A., Richards, C. A., Davis, S. T., and Good, S. S. (1994) Metabolism of 5-fluorocytidine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc. Natl. Acad. Sci. USA 91, 8302-8306.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8302-8306
-
-
Huber, B.F.1
Austin, E.A.2
Richards, C.A.3
Davis, S.T.4
Good, S.S.5
-
77
-
-
0031991630
-
Bystander tumoricidal effect and gap junctional communication in lung cancercells
-
Imaizumi, K., Hasegawa, Y., Kawabe, T., Emi, N., Saito, H., Naruse, K., and Shimokata, K. (1998) Bystander tumoricidal effect and gap junctional communication in lung cancercells. Am. J. Respir. Cell Mol. Biol. 18, 205-212.
-
(1998)
Am. J. Respir. Cell Mol. Biol.
, vol.18
, pp. 205-212
-
-
Imaizumi, K.1
Hasegawa, Y.2
Kawabe, T.3
Emi, N.4
Saito, H.5
Naruse, K.6
Shimokata, K.7
-
78
-
-
0030916131
-
Protection of herpes simplex virus thymidine kinase-transduced cells fromganciclovir-mediated cytotoxicityby bystander cells: The good Samaritan effect
-
Wygoda, M. R., Wilson, M. R., Davis, M. A., Trosko, J. E., Rehemtulla, A., and Lawrence, T. S. (1997) Protection of herpes simplex virus thymidine kinase-transduced cells fromganciclovir-mediated cytotoxicityby bystander cells: the good Samaritan effect. Cancer Res. 57, 1699-1703.
-
(1997)
Cancer Res.
, vol.57
, pp. 1699-1703
-
-
Wygoda, M.R.1
Wilson, M.R.2
Davis, M.A.3
Trosko, J.E.4
Rehemtulla, A.5
Lawrence, T.S.6
-
79
-
-
0034108850
-
Gap junctions: The "kiss of death" and the "kiss of life"
-
Andrade-Rosental, A. F., Rosental, R., Hopperstad, M. D., Wu, J. K., Vrionis, F. D., and Spray, D. C. (2000) Gap junctions: the "kiss of death" and the "kiss of life." Brain Res. Rev. 32, 308-315.
-
(2000)
Brain Res. Rev.
, vol.32
, pp. 308-315
-
-
Andrade-Rosental, A.F.1
Rosental, R.2
Hopperstad, M.D.3
Wu, J.K.4
Vrionis, F.D.5
Spray, D.C.6
-
80
-
-
0032213438
-
Enhancement of the herpes simplex virus thymidine kinase/ganciclovir bystander effect and its antitumor efficacy in vivo by pharmacologic manipulation of gap junctions
-
Touraine, R. L., Vahanian, N., Ramsey, W. J., and Blaese, R. M. (1998) Enhancement of the herpes simplex virus thymidine kinase/ganciclovir bystander effect and its antitumor efficacy in vivo by pharmacologic manipulation of gap junctions. Hum. Gene Ther. 9, 2385-2391.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 2385-2391
-
-
Touraine, R.L.1
Vahanian, N.2
Ramsey, W.J.3
Blaese, R.M.4
-
81
-
-
0032440742
-
The bystander effect in the HSVtk/ganciclovir system and its relation to gap junctional communication
-
Touraine, R. L., Ishii-Morita, H., Ramsey, W. J., and Blaese, R. M. (1998) The bystander effect in the HSVtk/ganciclovir system and its relation to gap junctional communication. Gene Ther. 5, 1705-1711.
-
(1998)
Gene Ther.
, vol.5
, pp. 1705-1711
-
-
Touraine, R.L.1
Ishii-Morita, H.2
Ramsey, W.J.3
Blaese, R.M.4
-
82
-
-
0033669748
-
The role of cellular- and prodrug-associated factors in the bystander effect induced by the Varicella zoster and Herpes simplex viral thymidine kinases in suicide gene therapy
-
Grignet-Debrus, C., Cool, V., Baudson, N., Velu, T., and Calberg-Bacq, C.-M. (2000) The role of cellular- and prodrug-associated factors in the bystander effect induced by the Varicella zoster and Herpes simplex viral thymidine kinases in suicide gene therapy. Cancer Gene Ther. 7, 1456-1468.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1456-1468
-
-
Grignet-Debrus, C.1
Cool, V.2
Baudson, N.3
Velu, T.4
Calberg-Bacq, C.-M.5
-
83
-
-
0029112774
-
Gene therapy of hepatoma: Bystander effect s and non-apoptotic cell death induced by thymidine kinase and ganciclovir
-
Kaneko, Y. and Tsukamoto, A. (1995) Gene therapy of hepatoma: bystander effect s and non-apoptotic cell death induced by thymidine kinase and ganciclovir. Cancer Lett. 96, 105-110.
-
(1995)
Cancer Lett.
, vol.96
, pp. 105-110
-
-
Kaneko, Y.1
Tsukamoto, A.2
-
84
-
-
0030007803
-
In vivo analysis of the "bystander effect": A cytokine cascade
-
Ramesh, R., Marrogi, A. J., Munshi, A., Abboud, C. N., and Freeman, S. M. (1996) In vivo analysis of the "bystander effect": a cytokine cascade. Exp. Hematol. 24, 829-838.
-
(1996)
Exp. Hematol.
, vol.24
, pp. 829-838
-
-
Ramesh, R.1
Marrogi, A.J.2
Munshi, A.3
Abboud, C.N.4
Freeman, S.M.5
-
85
-
-
0035106088
-
Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis
-
Agard, C., Ligeza, C., Dupas, B., et al. (2001) Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis. Cancer Gene Ther. 8, 128-136.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 128-136
-
-
Agard, C.1
Ligeza, C.2
Dupas, B.3
-
86
-
-
0033914768
-
Efficacy of herpes simplex virus thymidine kinase in combination with cytokine gene therapy in an experimental metastatic breast cancer model
-
Majumdar, A., Zolotorev, A., Samuel, S., et al. (2000) Efficacy of herpes simplex virus thymidine kinase in combination with cytokine gene therapy in an experimental metastatic breast cancer model. Cancer Gene Ther. 7, 1086-1099.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1086-1099
-
-
Majumdar, A.1
Zolotorev, A.2
Samuel, S.3
-
87
-
-
0034032940
-
Enhanced antitumoral effect of adenovirus-mediated cytosine deaminase gene therapy by induction of antigen-presenting cells through stem cell factor/granulocyte macrophage colony-stimu-lating factor gene transfer
-
Cao, X., Huang, X., Ju, D.W., Zhang, W.P., Hamada, H., and Wang, J. (2000) Enhanced antitumoral effect of adenovirus-mediated cytosine deaminase gene therapy by induction of antigen-presenting cells through stem cell factor/granulocyte macrophage colony-stimu-lating factor gene transfer. Cancer Gene Ther. 7, 177-186.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 177-186
-
-
Cao, X.1
Huang, X.2
Ju, D.W.3
Zhang, W.P.4
Hamada, H.5
Wang, J.6
-
88
-
-
0033918251
-
Absence of in vitro or in vivo bystander effects in a thymidine kinase-transduced murine T-lymphoma
-
Rivas, C., Chandler, P., Melo, J. V., Simpson, E., and Apperley, J. F. (2000) Absence of in vitro or in vivo bystander effects in a thymidine kinase-transduced murine T-lymphoma. Cancer Gene Ther. 7, 954-962.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 954-962
-
-
Rivas, C.1
Chandler, P.2
Melo, J.V.3
Simpson, E.4
Apperley, J.F.5
-
89
-
-
0035049257
-
Necrotic, rather than apoptotic death caused by cytochrome P450-activated ifosfamide
-
Karle, P., Renner, M., Salmons, B., and Gunzburg, W. H. (2001) Necrotic, rather than apoptotic death caused by cytochrome P450-activated ifosfamide. Cancer Gene Ther. 8, 220-230.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 220-230
-
-
Karle, P.1
Renner, M.2
Salmons, B.3
Gunzburg, W.H.4
|