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The active site water residue in all crystal structures in this manuscript are labeled as W1 to indicate the fact that they are all in the same position. The actual water numbering of W1 in the PDB files for each mutant is as follows: wild type CRABPII bound to RA (1CBS, W309), R132K:Y134F-CRABPII bound to RA (2G78, W11), R132K:Y134F-CRABPII bound to RT (2G79, W10).
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