De novo design of an enzyme

Science

Volumn 304, Issue 5679, 2004, Pages 1916-1917

  Sterner, Reinhard ^a   Schmid, Franz X ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DIHYDROXYACETONE PHOSPHATE; ENZYME; GLYCERALDEHYDE 3 PHOSPHATE; RECEPTOR; THIOREDOXIN; TRIOSEPHOSPHATE ISOMERASE; ESCHERICHIA COLI PROTEIN; GLUTAMIC ACID; HISTIDINE; LYSINE; PERIPLASMIC BINDING PROTEIN; RBSB PROTEIN, E COLI;

ENZYME;

ALGORITHM; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MATHEMATICAL COMPUTING; PRIORITY JOURNAL; REVIEW; BINDING SITE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DIRECTED MOLECULAR EVOLUTION; GENETICS; HYDROGEN BOND; METABOLISM; NOTE; PROTEIN CONFORMATION; PROTEIN ENGINEERING;

ALGORITHMS; AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DIRECTED MOLECULAR EVOLUTION; ESCHERICHIA COLI PROTEINS; GLUTAMIC ACID; GLYCERALDEHYDE 3-PHOSPHATE; HISTIDINE; HYDROGEN BONDING; LYSINE; MODELS, MOLECULAR; PERIPLASMIC BINDING PROTEINS; PROTEIN CONFORMATION; PROTEIN ENGINEERING; TRIOSE-PHOSPHATE ISOMERASE;

EID: 3042616160     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1100482     Document Type: Review

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