Stably folded de novo proteins from a designed combinatorial library

Protein Science

Volumn 12, Issue 1, 2003, Pages 92-102

  Wei, Yinan ^a,b   Liu, Tun ^b   Sazinsky, Stephen L ^a   Moffet, David A ^c   Pelczer, Istvà ^a   Hecht, Michael H ^a  

^a PRINCETON UNIVERSITY   (United States)

^b R W JOHNSON PHARMACEUTICAL RES I   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Binary patterning; Combinatorial library; De novo proteins; Four helix bundle; Native like protein structure; Protein design

Indexed keywords

ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; COMBINATORIAL LIBRARY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; COMBINATORIAL CHEMISTRY TECHNIQUES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE LIBRARY; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; PROTEINS;

EID: 12244272132     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0228003     Document Type: Article

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