Caffeine promotes apoptosis in mitotic spindle checkpoint-arrested cells

Journal of Biological Chemistry

Volumn 282, Issue 10, 2007, Pages 6954-6964

  Gabrielli, Brian ^a,b   Yu, Qian Chau ^a   Giles, Nichole ^a   Harding, Angus ^a,c   Stevens, Frankie ^a   Beamish, Heather ^a,d  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b NATIONAL HEALTH AND MEDICAL RESEARCH COUNCIL   (Australia)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Lions Medical Research

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CYCLIN; KINETOCHORES; MITOSIS; SPINDLE ASSEMBLY;

CELL DEATH; GENES; GROWTH KINETICS; METABOLISM; PROTEINS; SIGNAL TRANSDUCTION;

ORGANIC CHEMICALS;

CAFFEINE; CELL PROTEIN; CHECKPOINT KINASE 1; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; P21 ACTIVATED KINASE 1; PROTEASOME; PROTEIN MAD2; PROTEIN MPM 2; UNCLASSIFIED DRUG; 4 (4 (N BENZOYLAMINO)ANILINO) 6 METHOXY 7 (3 (1 MORPHOLINO)PROPOXY)QUINAZOLINE; 4-(4-(N-BENZOYLAMINO)ANILINO)-6-METHOXY-7-(3-(1-MORPHOLINO)PROPOXY)QUINAZOLINE; BENZAMIDE DERIVATIVE; PROTEIN SERINE THREONINE KINASE; QUINAZOLINE DERIVATIVE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE REGULATION; CENTROMERE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME MECHANISM; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MITOSIS SPINDLE; PRIORITY JOURNAL; PROTEIN FUNCTION; REDUCTION; CELL CYCLE G2 PHASE; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; MITOSIS; PHYSIOLOGY;

APOPTOSIS; BENZAMIDES; CAFFEINE; CELL LINE; G2 PHASE; HUMANS; MITOSIS; MITOTIC SPINDLE APPARATUS; PROTEIN-SERINE-THREONINE KINASES; QUINAZOLINES;

EID: 34147181531     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610104200     Document Type: Article

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