A mouse model of sitosterolemia: Absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol

BMC Medicine

Volumn 2, Issue , 2004, Pages

  Klett, Eric L ^a   Lu, Kangmo ^a   Kosters, Astrid ^b   Vink, Edwin ^b   Lee, Mi Hye ^a   Altenburg, Michael ^c   Shefer, Sarah ^d   Batta, Ashok K ^e   Yu, Hongwei ^a   Chen, Jianliang ^a   Klein, Richard ^a   Looije, Norbert ^b   Oude Elferink, Ronald ^b   Groen, Albert K ^b   Maeda, Nobuyo ^c   Salen, Gerald ^d,e   Patel, Shailendra B ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; CAMPESTEROL; CHOLESTEROL; LIPID; PHYTOSTEROL; SITOSTEROL; STEROLIN 2; UNCLASSIFIED DRUG; ABCG5 PROTEIN, MOUSE; ABCG8 PROTEIN, HUMAN; ABCG8 PROTEIN, MOUSE; BILE ACID; CLIONASTEROL; DRUG DERIVATIVE; GAMMA-SITOSTEROL; LIPOPROTEIN; SITOSTEROL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BILE; CONTROLLED STUDY; FEMALE; GENE DISRUPTION; GENE TARGETING; HEPATOBILIARY SYSTEM; HETEROZYGOSITY; HOMOZYGOSITY; INTESTINE; KNOCKOUT MOUSE; LIPID BLOOD LEVEL; LIVER; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SITOSTEROLEMIA; SURVIVAL; TISSUE LEVEL; WILD TYPE; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; GENE EXPRESSION; GENETICS; METABOLISM; MOUSE MUTANT; MUTATION; SECRETION (PROCESS);

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE; BILE ACIDS AND SALTS; CHOLESTEROL; FEMALE; GENE EXPRESSION; INTESTINES; LIPOPROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; MUTATION; PHYTOSTEROLS; SITOSTEROLS;

EID: 3042601466     PISSN: 17417015     EISSN: None     Source Type: Journal    
DOI: 10.1186/1741-7015-2-5     Document Type: Article

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