Niemann-Pick C1 like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

Journal of Biological Chemistry

Volumn 279, Issue 32, 2004, Pages 33586-33592

  Davis Jr , Harry R ^a   Zhu, Li Ji ^a   Hoos, Lizbeth M ^a   Tetzloff, Glen ^a   Maguire, Maureen ^a   Liu, Jianjun ^a   Yao, Xiaorui ^a   Iyer, Sai Prasad N ^a   Lam, My Hanh ^a   Lund, Erik G ^a   Detmers, Patricia A ^a   Graziano, Michael P ^a   Altmann, Scott W ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION; CHOLESTEROL; INITIATORS (CHEMICAL); PLASMAS; PROTEINS; SYNTHESIS (CHEMICAL);

ENTEROCYTES; LIPOPROTEINS; PHYTOSTEROLS;

BIOCHEMISTRY;

ABC TRANSPORTER A1; ABCG5 PROTEIN; ABCG8 PROTEIN; CARRIER PROTEIN; CHOLESTEROL; CHOLESTEROL TRANSPORTER; CHOLIC ACID; EZETIMIBE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; LIPOPROTEIN; MESSENGER RNA; NIEMANN PICK C1 LIKE 1 PROTEIN; PHYTOSTEROL; PROTEIN; SITOSTEROL; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CHOLESTEROL DIET; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; GENE EXPRESSION REGULATION; HYPERCHOLESTEROLEMIA; INTESTINE ABSORPTION; INTESTINE CELL; JEJUNUM; LIPOPROTEIN BLOOD LEVEL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL MOUSE; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ANIMALS; BIOLOGICAL TRANSPORT; CHOLESTEROL; CHOLESTEROL, DIETARY; HOMEOSTASIS; HYPERCHOLESTEROLEMIA; INTESTINAL ABSORPTION; INTESTINES; LIPOPROTEINS; LIVER; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHYTOSTEROLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SITOSTEROLS; TRIGLYCERIDES;

ANIMALIA;

EID: 4043124013     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405817200     Document Type: Article

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