Reduced cholesterol absorption upon PPARδ activation coincides with decreased intestinal expression of NPC1L1

Journal of Lipid Research

Volumn 46, Issue 3, 2005, Pages 526-534

  Van Der Veen, Jelske N ^a   Kruit, Janine K ^a   Havinga, Rick ^a   Baller, Julius F W ^a   Chimini, Giovanna ^b   Lestavel, Sophie ^c   Staels, Bart ^c   Groot, Pieter H E ^d   Groen, Albert K ^e   Kuipers, Folkert ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Center of Immunology   (France)

^c INSERM   (France)

^d GLAXOSMITHKLINE   (United Kingdom)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

High density lipoprotein cholesterol; Niemann Pick C1 like 1; Nuclear receptors; Peroxisome proliferator activated receptor

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; ABC TRANSPORTER G5; ABC TRANSPORTER G8; CHOLESTEROL; CHOLESTEROL ABSORPTION PROTEIN; GW 610742; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; NIEMANN PICK C1 LIKE 1 PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PROTEIN; UNCLASSIFIED DRUG; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; CARRIER PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; NPC1L1 PROTEIN, HUMAN; NPC1L1 PROTEIN, MOUSE; STEROL; THIAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG TARGETING; FECES; FEMALE; GENE EXPRESSION; INTESTINE ABSORPTION; LIVER; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR SENSITIVITY; STATISTICAL SIGNIFICANCE; UPREGULATION; WILD TYPE; ANIMAL; BLOOD; CELL STRAIN CACO 2; COMPARATIVE STUDY; DBA MOUSE; DRUG POTENTIATION; GENETICS; HUMAN; INTESTINE; MACROPHAGE; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; TIME;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CACO-2 CELLS; CHOLESTEROL; CHOLESTEROL, HDL; FEMALE; HUMANS; INTESTINAL ABSORPTION; INTESTINES; MACROPHAGES; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED DBA; MICE, KNOCKOUT; PPAR DELTA; PROTEINS; RNA, MESSENGER; STEROLS; THIAZOLES; TIME FACTORS;

EID: 22344449773     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M400400-JLR200     Document Type: Article

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