메뉴 건너뛰기




Volumn 276, Issue 5 39-5, 1999, Pages

Genetic differences in cholesterol absorption in 129/Sv and C57BL/6 mice: Effect on cholesterol responsiveness

Author keywords

Cholesterol esterification; Cholesterol transport; Fecal sterol excretion; Hepatic sterol synthesis; Small intestine

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLIC ACID; SITOSTANOL;

EID: 0032973755     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.5.g1117     Document Type: Article
Times cited : (55)

References (44)
  • 1
    • 0032500649 scopus 로고    scopus 로고
    • Identification of a form of acyl-CoA:Cholesterol acyltransferase specific to liver and intestine in nonhuman primates
    • Anderson, R. A., C. Joyce, M. Davis, J. W. Reagan, M. Clark, G. S. Shelness, and L. L. Rudel. Identification of a form of acyl-CoA:cholesterol acyltransferase specific to liver and intestine in nonhuman primates. J. Biol. Chem. 273: 26747-26754, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 26747-26754
    • Anderson, R.A.1    Joyce, C.2    Davis, M.3    Reagan, J.W.4    Clark, M.5    Shelness, G.S.6    Rudel, L.L.7
  • 2
    • 0019199986 scopus 로고
    • Cholesterol absorption and turnover in rhesus monkeys as measured by two methods
    • Bhattacharyya, A. K., and D. A. Eggen. Cholesterol absorption and turnover in rhesus monkeys as measured by two methods. J. Lipid Res. 21: 518-524, 1980.
    • (1980) J. Lipid Res. , vol.21 , pp. 518-524
    • Bhattacharyya, A.K.1    Eggen, D.A.2
  • 3
    • 0030829268 scopus 로고    scopus 로고
    • Genetic variation in cholesterol absorption efficiency among inbred strains of mice
    • Carter, C. P., P. N. Howles, and D. Y. Hui. Genetic variation in cholesterol absorption efficiency among inbred strains of mice. J. Nutr. 127: 1344-1348, 1997.
    • (1997) J. Nutr. , vol.127 , pp. 1344-1348
    • Carter, C.P.1    Howles, P.N.2    Hui, D.Y.3
  • 5
    • 0029051753 scopus 로고
    • Effects of hyodeoxycholic acid and α-hyocholic acid, two 6 α-hydroxylated bile acids, on cholesterol and bile acid metabolism in the hamster
    • Cohen-Solal, C., M. Parquet, J. Férézou, C. Sérougne, and C. Lutton. Effects of hyodeoxycholic acid and α-hyocholic acid, two 6 α-hydroxylated bile acids, on cholesterol and bile acid metabolism in the hamster. Biochim. Biophys. Acta 1257: 189-197, 1995.
    • (1995) Biochim. Biophys. Acta , vol.1257 , pp. 189-197
    • Cohen-Solal, C.1    Parquet, M.2    Férézou, J.3    Sérougne, C.4    Lutton, C.5
  • 6
    • 0028918775 scopus 로고
    • Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes
    • Farese, R. V., Jr., S. L. Ruland, L. M. Flynn, R. P. Stokowski, and S. G. Young. Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes. Proc. Natl. Acad. Sci. USA 92: 1774-1778, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1774-1778
    • Farese R.V., Jr.1    Ruland, S.L.2    Flynn, L.M.3    Stokowski, R.P.4    Young, S.G.5
  • 7
    • 0031706594 scopus 로고    scopus 로고
    • Caveolin is present in intestinal cells: Role in cholesterol trafficking?
    • Field, F. J., E. Born, S. Murthy, and S. N. Mathur. Caveolin is present in intestinal cells: role in cholesterol trafficking? J. Lipid Res. 39: 1938-1950, 1998.
    • (1998) J. Lipid Res. , vol.39 , pp. 1938-1950
    • Field, F.J.1    Born, E.2    Murthy, S.3    Mathur, S.N.4
  • 9
    • 0030947679 scopus 로고    scopus 로고
    • Established and emerging strategies for inhibition of cholesterol absorption
    • Homan, R., and B. R. Krause. Established and emerging strategies for inhibition of cholesterol absorption. Current Pharm. Design 3: 29-44, 1997.
    • (1997) Current Pharm. Design , vol.3 , pp. 29-44
    • Homan, R.1    Krause, B.R.2
  • 10
    • 0029989318 scopus 로고    scopus 로고
    • Dietary free and esterified cholesterol absorption in cholesterol esterase (bile salt-stimulated lipase) gene-targeted mice
    • Howles, P. N., C. P. Carter, and D. Y. Hui. Dietary free and esterified cholesterol absorption in cholesterol esterase (bile salt-stimulated lipase) gene-targeted mice. J. Biol. Chem. 271: 7196-7202, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7196-7202
    • Howles, P.N.1    Carter, C.P.2    Hui, D.Y.3
  • 11
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi, S., M. S. Brown, J. L. Goldstein, R. D. Gerard, R. E. Hammer, and J. Herz. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest. 92: 883-893, 1993.
    • (1993) J. Clin. Invest. , vol.92 , pp. 883-893
    • Ishibashi, S.1    Brown, M.S.2    Goldstein, J.L.3    Gerard, R.D.4    Hammer, R.E.5    Herz, J.6
  • 13
    • 0023544459 scopus 로고
    • Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population
    • Kesäniemi, Y. A., and T. A. Miettinen. Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population. Eur. J. Clin. Invest. 17: 391-395, 1987.
    • (1987) Eur. J. Clin. Invest. , vol.17 , pp. 391-395
    • Kesäniemi, Y.A.1    Miettinen, T.A.2
  • 15
    • 0029134079 scopus 로고
    • Hyper-and hypo-responsiveness to dietary fat and cholesterol among inbred mice: Searching for level and variability genes
    • Kirk, E. A., G. L. Moe, M. T. Caldwell, J. Å. Lernmark, D. L. Wilson, and R. C. LeBoeuf. Hyper-and hypo-responsiveness to dietary fat and cholesterol among inbred mice: searching for level and variability genes. J. Lipid Res. 36: 1522-1532, 1995.
    • (1995) J. Lipid Res. , vol.36 , pp. 1522-1532
    • Kirk, E.A.1    Moe, G.L.2    Caldwell, M.T.3    Lernmark J., Å.4    Wilson, D.L.5    LeBoeuf, R.C.6
  • 16
    • 0030960169 scopus 로고    scopus 로고
    • Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels
    • Kozarsky, K. F., M. H. Donahee, A. Rigotti, S. N. Iqbal, E. R. Edelman, and M. Krieger. Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels. Nature 387: 414-417, 1997.
    • (1997) Nature , vol.387 , pp. 414-417
    • Kozarsky, K.F.1    Donahee, M.H.2    Rigotti, A.3    Iqbal, S.N.4    Edelman, E.R.5    Krieger, M.6
  • 18
    • 0027153918 scopus 로고
    • The role of cholesterol absorption and hepatic cholesterol content in high and low responses to dietary cholesterol and fat in pedigreed baboons (Papio species)
    • Kushwaha, R. S., K. S. Rice, D. S. Lewis, H. C. McGill, Jr., and K. D. Carey. The role of cholesterol absorption and hepatic cholesterol content in high and low responses to dietary cholesterol and fat in pedigreed baboons (Papio species). Metabolism 42: 714-722, 1993.
    • (1993) Metabolism , vol.42 , pp. 714-722
    • Kushwaha, R.S.1    Rice, K.S.2    Lewis, D.S.3    McGill H.C., Jr.4    Carey, K.D.5
  • 19
    • 0031847230 scopus 로고    scopus 로고
    • Immunodepletion experiments suggest that acyl-coenzyme a:Cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines
    • Lee, O., C. C. Chang, W. Lee, and T.-Y. Chang. Immunodepletion experiments suggest that acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) protein plays a major catalytic role in adult human liver, adrenal gland, macrophages, and kidney, but not in intestines. J. Lipid Res. 39: 1722-1727, 1998.
    • (1998) J. Lipid Res. , vol.39 , pp. 1722-1727
    • Lee, O.1    Chang, C.C.2    Lee, W.3    Chang, T.-Y.4
  • 20
    • 0030893854 scopus 로고    scopus 로고
    • Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism
    • Machleder, D., B. Ivandic, C. Welch, L. Castellani, K. Reue, and A. J. Lusis. Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism. J. Clin. Invest. 99: 1406-1419, 1997.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1406-1419
    • Machleder, D.1    Ivandic, B.2    Welch, C.3    Castellani, L.4    Reue, K.5    Lusis, A.J.6
  • 21
    • 0021827538 scopus 로고
    • The absorption of cholesterol and the sterol balance in the Tarahumara Indians of Mexico fed cholesterol-free and high cholesterol diets
    • McMurry, M. P., W. E. Connor, D. S. Lin, M. T. Cerqueira, and S. L. Connor. The absorption of cholesterol and the sterol balance in the Tarahumara Indians of Mexico fed cholesterol-free and high cholesterol diets. Am. J. Clin. Nutr. 41: 1289-1298, 1985.
    • (1985) Am. J. Clin. Nutr. , vol.41 , pp. 1289-1298
    • McMurry, M.P.1    Connor, W.E.2    Lin, D.S.3    Cerqueira, M.T.4    Connor, S.L.5
  • 22
    • 0023930868 scopus 로고
    • Report of the National Cholesterol Education Program Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults
    • The National Cholesterol Education Program Expert Panel. Report of the National Cholesterol Education Program Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults. Arch. Intern. Med. 148: 36-69, 1988
    • (1988) Arch. Intern. Med. , vol.148 , pp. 36-69
  • 24
    • 0029989281 scopus 로고    scopus 로고
    • Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma
    • Osono, Y., L. A. Woollett, K. R. Marotti, G. W. Melchior, and J. M. Dietschy. Centripetal cholesterol flux from extrahepatic organs to the liver is independent of the concentration of high density lipoprotein-cholesterol in plasma. Proc. Natl. Acad. Sci. USA 93: 4114-4119, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4114-4119
    • Osono, Y.1    Woollett, L.A.2    Marotti, K.R.3    Melchior, G.W.4    Dietschy, J.M.5
  • 25
    • 0029163399 scopus 로고
    • Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse
    • Paigen, B. Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse. Am. J. Clin. Nutr. 62: 458S-462S, 1995.
    • (1995) Am. J. Clin. Nutr. , vol.62
    • Paigen, B.1
  • 26
    • 0013199471 scopus 로고    scopus 로고
    • Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor, LXRα
    • Peet, D. J., S. D. Turley, W. Ma, B. A. Janowski, J.-M. Lobaccaro, R. E. Hammer, and D. J. Mangelsdorf. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor, LXRα. Cell 93: 693-704, 1998.
    • (1998) Cell , vol.93 , pp. 693-704
    • Peet, D.J.1    Turley, S.D.2    Ma, W.3    Janowski, B.A.4    Lobaccaro, J.-M.5    Hammer, R.E.6    Mangelsdorf, D.J.7
  • 27
    • 0029101538 scopus 로고
    • Sterol carrier protein-2 is involved in cholesterol transfer from the endoplasmic reticulum to the plasma membrane in human fibroblasts
    • Puglielli, L., A. Rigotti, A. V. Greco, M. J. Santos, and F. Nervi. Sterol carrier protein-2 is involved in cholesterol transfer from the endoplasmic reticulum to the plasma membrane in human fibroblasts. J. Biol. Chem. 270: 18723-18726, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18723-18726
    • Puglielli, L.1    Rigotti, A.2    Greco, A.V.3    Santos, M.J.4    Nervi, F.5
  • 28
    • 0031705644 scopus 로고    scopus 로고
    • Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia
    • Schwarz, M., D. W. Russell, J. M. Dietschy, and S. D. Turley. Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia. J. Lipid. Res. 39: 1833-1843, 1998.
    • (1998) J. Lipid. Res. , vol.39 , pp. 1833-1843
    • Schwarz, M.1    Russell, D.W.2    Dietschy, J.M.3    Turley, S.D.4
  • 30
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano, H., J. D. Horton, R. E. Hammer, I. Shimomura, M. S. Brown, and J. L. Goldstein. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J. Clin. Invest. 98: 1575-1584, 1996.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 32
    • 0029019464 scopus 로고
    • Gene targeting approaches to complex genetic diseases: Atherosclerosis and essential hypertension
    • Smithies, O., and N. Maeda. Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension. Proc. Natl. Acad. Sci. USA 92: 5266-5272, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5266-5272
    • Smithies, O.1    Maeda, N.2
  • 33
    • 0019508827 scopus 로고
    • Effect of sucrose polyester on plasma lipids and cholesterol absorption in African green monkeys with variable hypercholesterolemic response to dietary cholesterol
    • St. Clair, R. W., L. L. Wood, and T. B. Clarkson. Effect of sucrose polyester on plasma lipids and cholesterol absorption in African green monkeys with variable hypercholesterolemic response to dietary cholesterol. Metabolism 30: 176-183, 1981.
    • (1981) Metabolism , vol.30 , pp. 176-183
    • St Clair, R.W.1    Wood, L.L.2    Clarkson, T.B.3
  • 34
    • 0032553417 scopus 로고    scopus 로고
    • Scavenger receptor, class B, type I-dependent stimulation of cholesterol esterification by high density lipoproteins, low density lipoproteins, and nonlipoprotein cholesterol
    • Stangl, H., G. Cao, K. L. Wyne, and H. H. Hobbs. Scavenger receptor, class B, type I-dependent stimulation of cholesterol esterification by high density lipoproteins, low density lipoproteins, and nonlipoprotein cholesterol. J. Biol. Chem. 273: 31002-31008, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31002-31008
    • Stangl, H.1    Cao, G.2    Wyne, K.L.3    Hobbs, H.H.4
  • 35
    • 0031153983 scopus 로고    scopus 로고
    • Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain
    • Threadgill, D. W., D. Yee, A. Matin, J. H. Nadeau, and T. Magnuson. Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain. Mamm. Genome 8: 390-393, 1997.
    • (1997) Mamm. Genome , vol.8 , pp. 390-393
    • Threadgill, D.W.1    Yee, D.2    Matin, A.3    Nadeau, J.H.4    Magnuson, T.5
  • 36
    • 0001297576 scopus 로고
    • Intestinal Lipid Absorption
    • edited by L. R. Johnson. New York: Raven
    • Tso, P. Intestinal Lipid Absorption. In: Physiology of the Gastrointestinal Tract, edited by L. R. Johnson. New York: Raven, 1994, p. 1867-1907.
    • (1994) Physiology of the Gastrointestinal Tract , pp. 1867-1907
    • Tso, P.1
  • 37
    • 0028085843 scopus 로고
    • Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver
    • Turley, S. D., B. P. Daggy, and J. M. Dietschy. Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver. Gastroenterology 107: 444-452, 1994.
    • (1994) Gastroenterology , vol.107 , pp. 444-452
    • Turley, S.D.1    Daggy, B.P.2    Dietschy, J.M.3
  • 38
    • 0002681759 scopus 로고
    • The metabolism and excretion of cholesterol by the liver
    • edited by I. M. Arias, W. B. Jakoby, H. Popper, D. Schachter, and D. A. Shafritz. New York: Raven
    • Turley, S. D., and J. M. Dietschy. The metabolism and excretion of cholesterol by the liver. In: The Liver: Biology and Pathobiology, edited by I. M. Arias, W. B. Jakoby, H. Popper, D. Schachter, and D. A. Shafritz. New York: Raven, 1988, p. 617-641.
    • (1988) The Liver: Biology and Pathobiology , pp. 617-641
    • Turley, S.D.1    Dietschy, J.M.2
  • 39
    • 0028157731 scopus 로고
    • Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster
    • Turley, S. D., M. W. Herndon, and J. M. Dietschy. Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster. J. Lipid Res. 35: 328-339, 1994.
    • (1994) J. Lipid Res. , vol.35 , pp. 328-339
    • Turley, S.D.1    Herndon, M.W.2    Dietschy, J.M.3
  • 40
    • 0031705365 scopus 로고    scopus 로고
    • Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low-and high-cholesterol diets
    • Turley, S. D., M. Schwarz, D. K. Spady, and J. M. Dietschy. Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low-and high-cholesterol diets. Hepatology 28: 1088-1094, 1998.
    • (1998) Hepatology , vol.28 , pp. 1088-1094
    • Turley, S.D.1    Schwarz, M.2    Spady, D.K.3    Dietschy, J.M.4
  • 41
    • 0030870628 scopus 로고    scopus 로고
    • Identification of a metabolic difference accounting for the hyper-and hyporesponder phenotypes of cynomolgus monkey
    • Turley, S. D., D. K. Spady, and J. M. Dietschy. Identification of a metabolic difference accounting for the hyper-and hyporesponder phenotypes of cynomolgus monkey. J. Lipid Res. 38: 1598-1611, 1997.
    • (1997) J. Lipid Res. , vol.38 , pp. 1598-1611
    • Turley, S.D.1    Spady, D.K.2    Dietschy, J.M.3
  • 43
    • 0000356477 scopus 로고    scopus 로고
    • Hyposecretion of biliary phospholipids (PL) significantly decreases the intestinal absorption of cholesterol (Ch) in Mdr2(-/-) and (+/-) mice
    • Wang, D. Q.-H., F. Lammert, B. Paigen, and M. C. Carey. Hyposecretion of biliary phospholipids (PL) significantly decreases the intestinal absorption of cholesterol (Ch) in Mdr2(-/-) and (+/-) mice. Gastroenterology 114: G3744, 1998.
    • (1998) Gastroenterology , vol.114
    • Wang, D.Q.-H.1    Lammert, F.2    Paigen, B.3    Carey, M.C.4
  • 44
    • 0029585129 scopus 로고
    • Apolipoprotein E competitively inhibits receptor-dependent low density lipoprotein uptake by the liver but has no effect on cholesterol absorption or synthesis in the mouse
    • Woollett, L. A., Y. Osono, J. Herz, and J. M. Dietschy. Apolipoprotein E competitively inhibits receptor-dependent low density lipoprotein uptake by the liver but has no effect on cholesterol absorption or synthesis in the mouse. Proc. Natl. Acad. Sci. USA 92: 12500-12504, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12500-12504
    • Woollett, L.A.1    Osono, Y.2    Herz, J.3    Dietschy, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.