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Volumn 39, Issue 9, 1998, Pages 1833-1843

Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase- deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

Author keywords

Bile acid pool size; Cholesterol 7 hydroxylase; Cholesterol absorption; Cholesterol synthesis; Liver; Small intestine

Indexed keywords

BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE;

EID: 0031705644     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (214)

References (49)
  • 1
    • 77956808656 scopus 로고
    • Cholesterol absorption and metabolism by the intestinal epithelium
    • H. Danielsson, and J. Sjövall, editors. Elsevier Science Publishers, New York.
    • Stange, E. F., and J. M. Dietschy. 1985. Cholesterol absorption and metabolism by the intestinal epithelium. In Sterols and Bile Acids. H. Danielsson, and J. Sjövall, editors. Elsevier Science Publishers, New York. 121-149.
    • (1985) Sterols and Bile Acids , pp. 121-149
    • Stange, E.F.1    Dietschy, J.M.2
  • 2
    • 15144355990 scopus 로고
    • The uptake of lipids into the intestinal mucosa
    • T. E. Andreoli, J. F. Hoffman, D. D. Fanestil, and S. G. Schultz, editors. Plenum Medical Book Company, New York.
    • Westergaard, H., and J. M. Dietschy. 1987. The uptake of lipids into the intestinal mucosa. In Membrane Transport Processes in Organized Systems. T. E. Andreoli, J. F. Hoffman, D. D. Fanestil, and S. G. Schultz, editors. Plenum Medical Book Company, New York. 213-224.
    • (1987) Membrane Transport Processes in Organized Systems , pp. 213-224
    • Westergaard, H.1    Dietschy, J.M.2
  • 3
    • 0002681759 scopus 로고
    • The metabolism and excretion of cholesterol by the liver
    • I. M. Arias, W. B. Jakoby, H. Popper, D. Schachter, and D. A. Shafritz, editors. Raven Press, New York.
    • Turley, S. D., and J. M. Dietschy. 1988. The metabolism and excretion of cholesterol by the liver. In The Liver: Biology and Pathobiology. I. M. Arias, W. B. Jakoby, H. Popper, D. Schachter, and D. A. Shafritz, editors. Raven Press, New York. 617-641.
    • (1988) The Liver: Biology and Pathobiology , pp. 617-641
    • Turley, S.D.1    Dietschy, J.M.2
  • 5
    • 0027501003 scopus 로고
    • Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
    • Dietschy, J. M., S. D. Turley, and D. K. Spady. 1993. Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J. Lipid Res. 34: 1637-1659.
    • (1993) J. Lipid Res. , vol.34 , pp. 1637-1659
    • Dietschy, J.M.1    Turley, S.D.2    Spady, D.K.3
  • 6
    • 0004852203 scopus 로고
    • Bile acids regulate hepatic low density lipoprotein receptor activity in the hamster by altering cholesterol flux across the liver
    • Spady, D. K., E. F. Stange, L. E. Bilhartz, and J. M. Dietschy. 1986. Bile acids regulate hepatic low density lipoprotein receptor activity in the hamster by altering cholesterol flux across the liver. Proc. Natl. Acad. Sci. USA. 83: 1916-1920.
    • (1986) Proc. Natl. Acad. Sci. USA. , vol.83 , pp. 1916-1920
    • Spady, D.K.1    Stange, E.F.2    Bilhartz, L.E.3    Dietschy, J.M.4
  • 7
    • 0030969042 scopus 로고    scopus 로고
    • Regulation of fecal bile acid excretion in male golden Syrian hamsters fed a cereal based diet with and without added cholesterol
    • Turley, S. D., D. K. Spady, and J. M. Dietschy. 1997. Regulation of fecal bile acid excretion in male golden Syrian hamsters fed a cereal based diet with and without added cholesterol. Hepatology. 25: 797-803.
    • (1997) Hepatology , vol.25 , pp. 797-803
    • Turley, S.D.1    Spady, D.K.2    Dietschy, J.M.3
  • 9
    • 0014409946 scopus 로고
    • Metabolism of cholest-5-ene-3β, 26-diol in the rat and hamster
    • Wachtel, N., S. Emerman, and N. B. Javitt. 1968. Metabolism of cholest-5-ene-3β, 26-diol in the rat and hamster. J. Biol. Chem. 243: 5207-5212.
    • (1968) J. Biol. Chem. , vol.243 , pp. 5207-5212
    • Wachtel, N.1    Emerman, S.2    Javitt, N.B.3
  • 10
    • 0025045782 scopus 로고
    • Potential bile acid precursors in plasma - Possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man
    • Axelson, M., and J. Sjövall. 1990. Potential bile acid precursors in plasma - possible indicators of biosynthetic pathways to cholic and chenodeoxycholic acids in man. J. Steroid Biochem. 36: 631-640.
    • (1990) J. Steroid Biochem. , vol.36 , pp. 631-640
    • Axelson, M.1    Sjövall, J.2
  • 11
    • 0030845921 scopus 로고    scopus 로고
    • Identification and characterization of a mouse oxysterol 7α-hydroxylase cDNA
    • Schwarz, M., E. G. Lund, R. Lathe, I. Björkhem, and D. W. Russell. 1997. Identification and characterization of a mouse oxysterol 7α-hydroxylase cDNA. J. Biol. Chem. 272: 23995-24001.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23995-24001
    • Schwarz, M.1    Lund, E.G.2    Lathe, R.3    Björkhem, I.4    Russell, D.W.5
  • 12
    • 0025894157 scopus 로고
    • Regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat
    • Pandak, W. M., Y. C. Li, J. Y. L. Chiang, E. J. Studer, E. C. Gurley, D. M. Heuman, Z. R. Vlahcevic, and P. B. Hylemon. 1991. Regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat. J. Biol. Chem. 266: 3416-3421.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3416-3421
    • Pandak, W.M.1    Li, Y.C.2    Chiang, J.Y.L.3    Studer, E.J.4    Gurley, E.C.5    Heuman, D.M.6    Vlahcevic, Z.R.7    Hylemon, P.B.8
  • 13
    • 0029744419 scopus 로고    scopus 로고
    • Feedback regulation of hepatic 7α-hydroxylase expression by bile salts in the hamster
    • Spady, D. K., J. A. Cuthbert, M. N. Willard, and R. S. Meidell. 1996. Feedback regulation of hepatic 7α-hydroxylase expression by bile salts in the hamster. J. Biol. Chem. 271: 18623-18631.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18623-18631
    • Spady, D.K.1    Cuthbert, J.A.2    Willard, M.N.3    Meidell, R.S.4
  • 14
    • 0030773526 scopus 로고    scopus 로고
    • Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat
    • Vlahcevic, Z. R., R. T. Stravitz, D. M. Heuman, P. B. Hylemou, and W. M. Pandak. 1997. Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat. Gastroenterology. 113: 1949-1957.
    • (1997) Gastroenterology , vol.113 , pp. 1949-1957
    • Vlahcevic, Z.R.1    Stravitz, R.T.2    Heuman, D.M.3    Hylemou, P.B.4    Pandak, W.M.5
  • 15
    • 0029666289 scopus 로고    scopus 로고
    • Disruption of cholesterol 7α-hydroxylase gene in mice: I. Postnatal lethality reversed by bile acid and vitamin supplementation
    • Ishibashi, S., M. Schwarz, P. K. Frykman, J. Hetz, and D. W. Russell. 1996. Disruption of cholesterol 7α-hydroxylase gene in mice: I. Postnatal lethality reversed by bile acid and vitamin supplementation. J. Biol. Chem. 271: 18017-18023.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18017-18023
    • Ishibashi, S.1    Schwarz, M.2    Frykman, P.K.3    Hetz, J.4    Russell, D.W.5
  • 16
    • 0029666290 scopus 로고    scopus 로고
    • Disruption of cholesterol 7α-hydroxylase gene in mice: II. Bile acid deficiency overcome by induction of oxysterol 7α-hydroxylase
    • Schwarz, M., E. G. Lund, K. D. R. Setchell, H. J. Kayden, J. E. Zerwekh, I. Björkhem, J. Herz, and D. W. Russell. 1996. Disruption of cholesterol 7α-hydroxylase gene in mice: II. Bile acid deficiency overcome by induction of oxysterol 7α-hydroxylase. J. Biol. Chem. 271: 18024-18031.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18024-18031
    • Schwarz, M.1    Lund, E.G.2    Setchell, K.D.R.3    Kayden, H.J.4    Zerwekh, J.E.5    Björkhem, I.6    Herz, J.7    Russell, D.W.8
  • 17
    • 0028833385 scopus 로고
    • Role of liver in the synthesis of cholesterol and the clearance of low density lipoproteins in the cynomolgus monkey
    • Turley, S. D., D. K. Spady, and J. M. Dietschy. 1995. Role of liver in the synthesis of cholesterol and the clearance of low density lipoproteins in the cynomolgus monkey. J. Lipid Res. 36: 67-79.
    • (1995) J. Lipid Res. , vol.36 , pp. 67-79
    • Turley, S.D.1    Spady, D.K.2    Dietschy, J.M.3
  • 18
    • 0028929262 scopus 로고
    • Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse
    • Osono, Y., L. A. Woollett, J. Herz, and J. M. Dietschy. 1995. Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse. J. Clin. Invest. 95: 1124-1132.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1124-1132
    • Osono, Y.1    Woollett, L.A.2    Herz, J.3    Dietschy, J.M.4
  • 19
    • 0030870628 scopus 로고    scopus 로고
    • Identification of a metabolic difference accounting for the hyper- and hyporesponder phenotypes of cynomolgus monkey
    • Turley, S. D., D. K. Spady, and J. M. Dietschy. 1997. Identification of a metabolic difference accounting for the hyper- and hyporesponder phenotypes of cynomolgus monkey. J. Lipid Res. 38: 1598-1611.
    • (1997) J. Lipid Res. , vol.38 , pp. 1598-1611
    • Turley, S.D.1    Spady, D.K.2    Dietschy, J.M.3
  • 20
    • 0028085843 scopus 로고
    • Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver
    • Turley, S. D., B. P. Daggy, and J. M. Dietschy. 1994. Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver. Gastroenterology. 107: 444-452.
    • (1994) Gastroenterology , vol.107 , pp. 444-452
    • Turley, S.D.1    Daggy, B.P.2    Dietschy, J.M.3
  • 21
    • 0030044508 scopus 로고    scopus 로고
    • Effect of feeding psyllium and cholestyramine in combination on low density lipoprotein metabolism and fecal bile acid excretion in hamsters with dietary-induced hypercholesterolemia
    • Turley, S. D., B. P. Daggy, and J. M. Dietschy. 1996. Effect of feeding psyllium and cholestyramine in combination on low density lipoprotein metabolism and fecal bile acid excretion in hamsters with dietary-induced hypercholesterolemia. J. Cardiovasc. Pharmacol. 27: 71-79.
    • (1996) J. Cardiovasc. Pharmacol. , vol.27 , pp. 71-79
    • Turley, S.D.1    Daggy, B.P.2    Dietschy, J.M.3
  • 22
    • 0028157731 scopus 로고
    • Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster
    • Turley, S. D., M. W. Herndon, and J. M. Dietschy. 1994. Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster. J. Lipid Res. 35: 328-339.
    • (1994) J. Lipid Res. , vol.35 , pp. 328-339
    • Turley, S.D.1    Herndon, M.W.2    Dietschy, J.M.3
  • 23
    • 0026093637 scopus 로고
    • Cholesterol-lowering action of psyllium mucilloid in the hamster: Sites and possible mechanisms of action
    • Turley, S. D., B. P. Daggy, and J. M. Dietschy. 1991. Cholesterol-lowering action of psyllium mucilloid in the hamster: sites and possible mechanisms of action. Metabolism. 40: 1063-1073.
    • (1991) Metabolism , vol.40 , pp. 1063-1073
    • Turley, S.D.1    Daggy, B.P.2    Dietschy, J.M.3
  • 25
    • 0019481094 scopus 로고
    • Rales of sterol synthesis and uptake in the major organs of the rat in vivo
    • Turley, S. D., J. M. Andersen, and J. M. Dieischy. 1981. Rales of sterol synthesis and uptake in the major organs of the rat in vivo. J. Lipid Res. 22: 551-569.
    • (1981) J. Lipid Res. , vol.22 , pp. 551-569
    • Turley, S.D.1    Andersen, J.M.2    Dieischy, J.M.3
  • 26
    • 0021676528 scopus 로고
    • Measurement of rates of cholesterol synthesis using tritiated waler
    • Dieischy, J. M., and D. K. Spady. 1984. Measurement of rates of cholesterol synthesis using tritiated waler. J. Lipid Res. 25: 1469-1476.
    • (1984) J. Lipid Res. , vol.25 , pp. 1469-1476
    • Dieischy, J.M.1    Spady, D.K.2
  • 27
    • 0017913374 scopus 로고
    • A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes
    • Kessler, M., O. Acuto, C. Storelli, H. Murer, M. Müller, and G. Semenza. 1978. A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Biochim. Biophys. Acta. 506: 136-154.
    • (1978) Biochim. Biophys. Acta , vol.506 , pp. 136-154
    • Kessler, M.1    Acuto, O.2    Storelli, C.3    Murer, H.4    Müller, M.5    Semenza, G.6
  • 30
    • 0028039878 scopus 로고
    • Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter
    • Wong, M. H., P. Oelkers, A. L. Graddock, and P. A. Dawson. 1994. Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter. J. Biol. Chem. 269: 1340-1347.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1340-1347
    • Wong, M.H.1    Oelkers, P.2    Graddock, A.L.3    Dawson, P.A.4
  • 31
    • 0023870107 scopus 로고
    • Interaction of dietary cholesterol and triglycerides in the regulation of hepatic low density lipoprotein transport in the hamster
    • Spady, D. K., and J. M. Dieischy. 1988. Interaction of dietary cholesterol and triglycerides in the regulation of hepatic low density lipoprotein transport in the hamster. J. Clin. Invest. 81: 300-309.
    • (1988) J. Clin. Invest. , vol.81 , pp. 300-309
    • Spady, D.K.1    Dieischy, J.M.2
  • 32
    • 0023484120 scopus 로고
    • Hypoand hyperresponders: Individual differences in the response of serum cholesterol concentration to changes in diet
    • Beynen, A. C., M. B. Katan, and L. F M. Van Zutphen. 1987. Hypoand hyperresponders: individual differences in the response of serum cholesterol concentration to changes in diet. Adv. Lipid Res. 22: 115-171.
    • (1987) Adv. Lipid Res. , vol.22 , pp. 115-171
    • Beynen, A.C.1    Katan, M.B.2    Van Zutphen, L.F.M.3
  • 33
    • 0029585129 scopus 로고
    • Apolipoprotein e competitively inhibits receptor-dependent low density lipoprotein uptake by the liver but has no effect on cholesterol absorption or synthesis in the mouse
    • Woollett, L. A., Y. Osono, J. Herz, and J. M. Dietschy. 1995. Apolipoprotein E competitively inhibits receptor-dependent low density lipoprotein uptake by the liver but has no effect on cholesterol absorption or synthesis in the mouse. Prof. Natl. Acad. Sci. USA. 92: 12500-12504.
    • (1995) Prof. Natl. Acad. Sci. USA , vol.92 , pp. 12500-12504
    • Woollett, L.A.1    Osono, Y.2    Herz, J.3    Dietschy, J.M.4
  • 34
    • 0002230202 scopus 로고
    • Familial Hypercholesterolemia
    • C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York.
    • Goldstein, J. L., and M. E. Brown. 1989. Familial Hypercholesterolemia. In The Metabolic Basis of Inherited Disease. C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York. 1215-1250.
    • (1989) The Metabolic Basis of Inherited Disease , pp. 1215-1250
    • Goldstein, J.L.1    Brown, M.E.2
  • 35
    • 0019199986 scopus 로고
    • Cholesterol absorption and turnover in rhesus monkeys as measured by two methods
    • Bhattacharyya, A. K., and D. A. Eggen. 1980. Cholesterol absorption and turnover in rhesus monkeys as measured by two methods. J. Lipid Res. 21:518-524.
    • (1980) J. Lipid Res. , vol.21 , pp. 518-524
    • Bhattacharyya, A.K.1    Eggen, D.A.2
  • 36
    • 0019508827 scopus 로고
    • Effect of sucrose polyester on plasma lipids and cholesterol absorption in African green monkeys with variable hypercholesterolemic response to dietary cholesterol
    • St. Clair, R. W., L. L. Wood, and T. B. Clarkson. 1981. Effect of sucrose polyester on plasma lipids and cholesterol absorption in African green monkeys with variable hypercholesterolemic response to dietary cholesterol. Metabolism. 30: 176-183.
    • (1981) Metabolism , vol.30 , pp. 176-183
    • St Clair, R.W.1    Wood, L.L.2    Clarkson, T.B.3
  • 37
    • 0023544459 scopus 로고
    • Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population
    • Kesäniemi, Y. A., and T. A. Miettinen. 1987. Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population. Eur. J. Clin. Invest. 17: 391-395.
    • (1987) Eur. J. Clin. Invest. , vol.17 , pp. 391-395
    • Kesäniemi, Y.A.1    Miettinen, T.A.2
  • 38
    • 0024347985 scopus 로고
    • Sterol balance and cholesterol absorption in inbred strains of rabbits hypo- Or hyperresponsive to dietary cholesterol
    • Beynen, A. C., G. W. Meijer, A. G. Lemmens, J. F. C. Glatz, A. Versluis, M. B. Katan, and L. F. M. Van Zutphen. 1989. Sterol balance and cholesterol absorption in inbred strains of rabbits hypo-or hyperresponsive to dietary cholesterol. Atherosclerosis. 77: 151-157.
    • (1989) Atherosclerosis , vol.77 , pp. 151-157
    • Beynen, A.C.1    Meijer, G.W.2    Lemmens, A.G.3    Glatz, J.F.C.4    Versluis, A.5    Katan, M.B.6    Van Zutphen, L.F.M.7
  • 40
    • 0019470775 scopus 로고
    • Origins of fecal neutral steroids in rats
    • Miettinen, T. A., A. Proia, and D. J. McNamara. 1981. Origins of fecal neutral steroids in rats. J. Lipid Res. 22: 485-495.
    • (1981) J. Lipid Res. , vol.22 , pp. 485-495
    • Miettinen, T.A.1    Proia, A.2    McNamara, D.J.3
  • 41
    • 12444305884 scopus 로고
    • The uptake of lipids into the intestinal mucosa
    • T. E. Andreoli, J. F. Hoffman, and D. D. Fanestil, editors. Plenum Publishing Corporation, New York.
    • Dietschy, J. M. 1978, The uptake of lipids into the intestinal mucosa. In Physiology of Membrane Disorders. T. E. Andreoli, J. F. Hoffman, and D. D. Fanestil, editors. Plenum Publishing Corporation, New York. 577-592.
    • (1978) Physiology of Membrane Disorders , pp. 577-592
    • Dietschy, J.M.1
  • 42
    • 0021043541 scopus 로고
    • Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit
    • Heider, J. G., C. E. Pickens, and L. A. Kelly. 1983. Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit. J. Lipid Res. 24: 1127-1134.
    • (1983) J. Lipid Res. , vol.24 , pp. 1127-1134
    • Heider, J.G.1    Pickens, C.E.2    Kelly, L.A.3
  • 43
    • 0017121838 scopus 로고
    • The mechanism whereby bile acid micelles increase the rate of fatly acid and cholesterol uptake into the intestinal mucosal cell
    • Westergaard, H., and J. M. Dietschy. 1976. The mechanism whereby bile acid micelles increase the rate of fatly acid and cholesterol uptake into the intestinal mucosal cell. J. Clin. Invest. 58: 97-108.
    • (1976) J. Clin. Invest. , vol.58 , pp. 97-108
    • Westergaard, H.1    Dietschy, J.M.2
  • 44
    • 0002541284 scopus 로고
    • General principles governing movement of lipids across biological membranes
    • A. M. Gotto, and J. A. Ontko, editors. Waverly Press, Inc., Baltimore.
    • Dietschy, J. M. 1978. General principles governing movement of lipids across biological membranes. In Disturbances in Lipid and Lipoprotein Metabolism. A. M. Gotto, and J. A. Ontko, editors. Waverly Press, Inc., Baltimore. 1-28.
    • (1978) Disturbances in Lipid and Lipoprotein Metabolism , pp. 1-28
    • Dietschy, J.M.1
  • 45
    • 0017334594 scopus 로고
    • Derivation of the equations that describe the effects of unstirred water layers on the kinetic parameters of active transport processes in the intestine
    • Thomson, A. B. R., and J. M. Dietschy. 1977. Derivation of the equations that describe the effects of unstirred water layers on the kinetic parameters of active transport processes in the intestine. J. Them. Biol. 64: 277-294.
    • (1977) J. Them. Biol. , vol.64 , pp. 277-294
    • Thomson, A.B.R.1    Dietschy, J.M.2
  • 46
    • 0015168026 scopus 로고
    • Differential diagnostic approach to clinical problems of absorption
    • Wilson, F. A., and J. M. Dietschy. 1971. Differential diagnostic approach to clinical problems of absorption. Gastroenterology. 61: 911-931.
    • (1971) Gastroenterology , vol.61 , pp. 911-931
    • Wilson, F.A.1    Dietschy, J.M.2
  • 47
    • 0015408220 scopus 로고
    • Approach to the malabsorption syndromes associated with disordered bile acid metabolism
    • Wilson, F. A., and J. M. Dietschy. 1972. Approach to the malabsorption syndromes associated with disordered bile acid metabolism. Arch. Intern. Med. 130: 584-594.
    • (1972) Arch. Intern. Med. , vol.130 , pp. 584-594
    • Wilson, F.A.1    Dietschy, J.M.2
  • 48
    • 0345584973 scopus 로고
    • Cholesterol synthesis in the squirrel monkey: Relative rates of synthesis in various tissues and mechanisms of control
    • Dietschy, J. M., and J. D. Wilson. 1968. Cholesterol synthesis in the squirrel monkey: relative rates of synthesis in various tissues and mechanisms of control. J. Clin. Invest. 47: 166-174.
    • (1968) J. Clin. Invest. , vol.47 , pp. 166-174
    • Dietschy, J.M.1    Wilson, J.D.2
  • 49
    • 0014251631 scopus 로고
    • The role of bile salts in controlling the rate of intestinal cholesterogenesis
    • Dietschy, J. M. 1968. The role of bile salts in controlling the rate of intestinal cholesterogenesis. J. Clin. Invest. 47: 286-300.
    • (1968) J. Clin. Invest. , vol.47 , pp. 286-300
    • Dietschy, J.M.1


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