The differential preference of scorpion α-toxins for insect or mammalian sodium channels: Implications for improved insect control

Toxicon

Volumn 49, Issue 4, 2007, Pages 452-472

  Gordon, Dalia ^a   Karbat, Izhar ^a   Ilan, Nitza ^a   Cohen, Lior ^a   Kahn, Roy ^a   Gilles, Nicolas ^b   Dong, Ke ^c   Stühmer, Walter ^d   Tytgat, Jan ^e   Gurevitz, Michael ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b DIF   (France)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^e UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Allosteric interactions; Insect sodium channel; Insecticidal toxins; Peptidomimetics; Receptor site 3; Scorpion toxins

Indexed keywords

ALKALOID; ALPHA TOXIN; NEUROTOXIN; POLYETHER; PYRETHROID; RECEPTOR PROTEIN; SCORPION VENOM; VOLTAGE GATED SODIUM CHANNEL;

ALLOSTERISM; ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING AFFINITY; ENVENOMATION; HUMAN; INSECT CONTROL; MEMBRANE POTENTIAL; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR SITE 3; REVIEW; SCORPION; SEA ANEMONE; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; GRASSHOPPERS; MOLECULAR SEQUENCE DATA; NEURONS; NEUROTOXINS; PEST CONTROL, BIOLOGICAL; PHOSPHOLIPASE C; PROTEIN CONFORMATION; RATS; SCORPION VENOMS; SCORPIONS; SODIUM CHANNELS;

ACTINIARIA; ARANEAE; HEXAPODA; MAMMALIA; SCORPIONES;

EID: 33847366129     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.11.016     Document Type: Review

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