Domain 2 of Drosophila Para Voltage-Gated Sodium Channel Confers Insect Properties to a Rat Brain Channel

Journal of Neuroscience

Volumn 22, Issue 11, 2002, Pages 4364-4371

  Shichor, Iris ^a,b   Zlotkin, Eliahu ^b   Ilan, Nitza ^a   Chikashvili, Dodo ^a   Stuhmer, Walter ^c   Gordon, Dalia ^a   Lotan, Ilana ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

Drosophila Para; Gating; Insect selectivity; Na channel; Scorpion toxin; Xenopus oocytes

Indexed keywords

CELL MEMBRANE PROTEIN; SCORPION VENOM; SODIUM CHANNEL; HYBRID PROTEIN; INSECT PROTEIN; NEUROTOXIN; SCORPION TOXIN I, ANDROCTONUS; TETRODOTOXIN;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BETA CHAIN; BINDING SITE; BRAIN; CHANNEL GATING; CHIMERA; CONTROLLED STUDY; DROSOPHILA; ELECTRIC POTENTIAL; FEMALE; INSECT; MOLECULAR RECOGNITION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; TEMPERATURE SENSITIVITY; XENOPUS; ANIMAL; CELL MEMBRANE POTENTIAL; DRUG EFFECT; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATCH CLAMP; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; RAT; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; DROSOPHILA; GENE EXPRESSION; INSECT PROTEINS; ION CHANNEL GATING; MEMBRANE POTENTIALS; NEUROTOXINS; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT FUSION PROTEINS; SCORPION VENOMS; SODIUM CHANNELS; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TETRODOTOXIN; TRANSFECTION; XENOPUS;

EID: 0036618134     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-11-04364.2002     Document Type: Article

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