Scorpion α and α-like toxins differentially interact with sodium channels in mammalian CNS and periphery

European Journal of Neuroscience

Volumn 12, Issue 8, 2000, Pages 2823-2832

  Gilles, Nicolas ^a   Chen, Haijun ^b   Wilson, Harry ^c   Le Gall, Frédéric ^d   Montoya, Gonzalo ^d   Molgo, Jordi ^d   Schönherr, Roland ^b   Nicholson, Graham ^c   Heinemann, Stefan H ^b   Gordon, Dalia ^a,e,f  

^a CEA SACLAY   (France)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^d LABORATOIRE DE NEUROBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

^e TEL AVIV UNIVERSITY   (Israel)

^f Sigyn Pharmaceuticals Ltd   (Israel)

Author keywords

DRG; Expression in HEK cells; Neuromuscular junction; Receptor site 3; Toxin interaction

Indexed keywords

SCORPION VENOM; SODIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN NERVE CELL; BRAIN SYNAPTOSOME; CENTRAL NERVOUS SYSTEM; HUMAN; HUMAN CELL; MAMMAL; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; SCORPION; SPINAL GANGLION;

ANIMALS; BINDING SITES; BRAIN; BRAIN CHEMISTRY; CELLS, CULTURED; FEMALE; GANGLIA, SPINAL; HUMANS; ION CHANNEL GATING; KIDNEY; MAMMALS; MEMBRANE POTENTIALS; MICE; MOLECULAR SEQUENCE DATA; MOTOR NEURONS; MUSCLE CONTRACTION; MUSCLE, SKELETAL; NEUROMUSCULAR JUNCTION; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; PHRENIC NERVE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SCORPION VENOMS; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM CHANNELS; SYNAPTOSOMES;

EID: 0033816689     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00168.x     Document Type: Article

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