Molecular modeling studies of estrogen receptor modulators

Current Computer-Aided Drug Design

Volumn 2, Issue 3, 2006, Pages 229-253

  Mukherjee, Subhendu ^a   Saha, Achintya ^a  

^a UNIVERSITY OF CALCUTTA   (India)

Author keywords

Descriptor; Docking; Molecular field and similarity analysis; Molecular modeling; Pharmacophore; QSAR; Selective estrogen receptor modulator

Indexed keywords

BINDING ENERGY; COMPUTATIONAL CHEMISTRY; MODULATORS; MOLECULAR GRAPHICS; MOLECULAR MODELING; PHARMACODYNAMICS; TISSUE;

DESCRIPTORS; DOCKING; ESTROGEN RECEPTOR; MOLECULAR FIELD ANALYSIS; MOLECULAR SIMILARITY; OESTROGENS; PHARMACOPHORES; QSAR; SELECTIVE ESTROGEN RECEPTOR MODULATORS; SIMILARITY ANALYSIS;

LIGANDS;

1,1,2 TRIPHENYLETHYLENE DERIVATIVE; 3 ALKYL 2,4,5 TRIARYLFURAN DERIVATIVE; ANTIESTROGEN; CARBORANE DERIVATIVE; CLOVER EXTRACT; CYCLOFENIL; DEOXYBENZOIN DERIVATIVE; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ETHAMOXYTRIPHETOL; GENISTEIN; GLYCYRRHIZA EXTRACT; ISOFLAVONE DERIVATIVE; PHYTOESTROGEN; PLANT EXTRACT; PYRAZOLE DERIVATIVE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; STEROID HORMONE RECEPTOR BLOCKING AGENT; TAMOXIFEN; TETRAHYDROISOQUINOLINE DERIVATIVE; TOREMIFENE; TRIARYLCYCLOPROPYL DERIVATIVE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ALGORITHM; ALZHEIMER DISEASE; ANTINEOPLASTIC ACTIVITY; BINDING AFFINITY; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER PREVENTION; CANCER RISK; CARDIOVASCULAR DISEASE; CELL SURVIVAL; COMPUTER AIDED DESIGN; COMPUTER MODEL; COMPUTER PROGRAM; CONFORMATIONAL TRANSITION; DNA BINDING; DNA TRANSCRIPTION; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENDOMETRIUM CANCER; HUMAN; INTERMETHOD COMPARISON; LIGAND BINDING; LIVER CARCINOGENESIS; LIVER TOXICITY; LONG TERM EXPOSURE; MEMORY; MOLECULAR DYNAMICS; MOLECULAR MODEL; NERVE CELL; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; PHARMACOPHORE; PHYSICAL CHEMISTRY; POSTMENOPAUSE OSTEOPOROSIS; PRINCIPAL COMPONENT ANALYSIS; PROTEIN DATA BANK; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; RISK ASSESSMENT; RISK REDUCTION; STATISTICS; TRANSCRIPTION INITIATION; TREATMENT OUTCOME;

EID: 33748702716     PISSN: 15734099     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340906778226391     Document Type: Review

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