Cysteine proteinase inhibitors as therapy for parasitic diseases: Advances in inhibitor design

Mini-Reviews in Medicinal Chemistry

Volumn 6, Issue 9, 2006, Pages 1025-1032

  Steverding, Dietmar ^a   Caffrey, Conor R ^b   Sajid, Mohammed ^b  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brucipain; Cruzain; Falcipain; Leishmania spp.; Plasmodium spp.; Rhodesain; Trypanosoma spp.; Vivapain

Indexed keywords

ANTIPARASITIC AGENT; CATHEPSIN B; CRUZIPAIN; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDYL PEPTIDASE; NITRIC OXIDE DONOR;

ANTIPROTOZOAL ACTIVITY; BINDING AFFINITY; DRUG DESIGN; DRUG EFFICACY; DRUG IDENTIFICATION; DRUG INDUSTRY; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; HUMAN; LEISHMANIASIS; MALARIA; NONHUMAN; PARASITOSIS; PHYSICAL CHEMISTRY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; STRUCTURE ACTIVITY RELATION; SURVIVAL; TRYPANOSOMIASIS; VALIDATION PROCESS;

CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; HUMANS; MOLECULAR STRUCTURE; PARASITIC DISEASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748645559     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955706778195207     Document Type: Review

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