Chalcone, Acyl Hydrazide, and Related Amides Kill Cultured Trypanosoma brucei brucei

Molecular Medicine

Volumn 6, Issue 8, 2000, Pages 660-669

  Troeberg, Linda ^a   Chen, Xiaowu ^b   Flaherty, Terrence M ^b   Morty, Rory E ^a   Cheng, Maosheng ^b   Hua, Huiming ^b   Springer, Clayton ^b   McKerrow, James H ^b,c   Kenyon, George L ^b   Lonsdale Eccles, John D ^a   Coetzer, Theresa H T ^a   Cohen, Fred E ^b,c  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acylhydrazides; Brucei Infection; Chalcone; Cysteine Protease Inhibitor; Reduce Parasite Numbers

Indexed keywords

AMIDE; ANTITRYPANOSOMAL AGENT; CATHEPSIN; CATHEPSIN L; CHALCONE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; HYDRAZINE DERIVATIVE; PROTEINASE; TRYPANOPAIN TB;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; HUMAN; IC 50; KINETICS; METABOLISM; MOUSE; PARASITOLOGY; SHEEP; TRYPANOSOMA BRUCEI; TRYPANOSOMIASIS;

AMIDES; ANIMALS; CATHEPSINS; CHALCONE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DISEASE MODELS, ANIMAL; ENDOPEPTIDASES; HUMANS; HYDRAZINES; INHIBITORY CONCENTRATION 50; KINETICS; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; SHEEP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS;

MLCS; MLOWN;

EID: 0034252808     PISSN: 10761551     EISSN: 15283658     Source Type: Journal    
DOI: 10.1007/BF03402046     Document Type: Article

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