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Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 1, 2005, Pages 121-123

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain

(10) Fujii, Naoaki a Mallari, Jeremy P a Hansell, Elizabeth J a MacKey, Z a Doyle, Patricia a Zhou, Y M a Gut, Jiri a Rosenthal, Philip J a McKerrow, James H a Guy, R Kiplin a

a UNIVERSITY OF CALIFORNIA (United States)

Author keywords

Chagas; Malaria; Protease inhibitor; Sleeping sickness; Thiosemicarbazone

Indexed keywords

ANTIPROTOZOAL AGENT; CRUZIPAIN; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; FALCIPAIN 2; PROTOZOAL PROTEIN; RHODESAIN; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ANTIPROTOZOAL ACTIVITY; ARTICLE; CHAGAS DISEASE; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; MALARIA; NONHUMAN; PARASITE CONTROL; PARASITE CULTIVATION; PARASITE VIRULENCE; PLASMODIUM FALCIPARUM; PROTOZOON; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI; TRYPANOSOMA RHODESIENSE;

CYSTEINE ENDOPEPTIDASES; ENZYME INHIBITORS; PROTOZOAN PROTEINS; THIOSEMICARBAZONES;

PLASMODIUM FALCIPARUM; TRYPANOSOMA; TRYPANOSOMA BRUCEI RHODESIENSE; TRYPANOSOMA CRUZI;

EID: 9644265257 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2004.10.023 Document Type: Article

Times cited : (151)

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