Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax

Biochemical Journal

Volumn 378, Issue 2, 2004, Pages 529-538

  Byoung Kuk, N A ^a,c   Shenai, Bhaskar R ^a   Sijwali, Puran S ^a   Choe, Youngchool ^b   Pandey, Kailash C ^b   Singh, Ajay ^b   Craik, Charles S ^b   Rosenthal, Philip J ^a,b,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Sungkyunkwan University   (South Korea)

^d SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

Cysteine protease; Haemoglobin; Plasmodium; Vivapain

Indexed keywords

ANTIMALARIAL ACTIVITY; HUMAN PATHOGENS;

AMINO ACIDS; ESCHERICHIA COLI; GENES; GENETIC ENGINEERING; HEMOGLOBIN; HYDROLYSIS; PATHOLOGY; PROTOZOA; SUBSTRATES;

ENZYMES;

ANTIMALARIAL AGENT; BENZYLOXYCARBONYLPHENYLALANYLARGINYL FLUOROMETHYL KETONE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; CYTOSKELETON PROTEIN; FALCIPAIN 2; FALCIPAIN 3; HEMOGLOBIN; LEUCINE; MORPHOLINE UREA LEUCYLHOMOPHENYLALANYL FLUOROMETHYL KETONE; MORPHOLINE UREA LEUCYLHOMOPHENYLALANYLPHENYLVINYLSULFONE; MORPHOLINE UREA PHENYLALANYLHOMOPHENYLALANYL FLUOROMETHYL KETONE; MORPHOLINE UREA PHENYLALANYLHOMOPHENYLALANYLPHENYLVINYLSULFONE; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; N METHYLPIPERAZINE UREA LEUCYLHOMOPHENYLALANYLPHENYLVINYLSULFONE; N METHYLPIPERAZINE UREA PHENYLALANYLHOMOPHENYLALANYLPHENYLVINYLSULFONE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIVAPAIN 2; VIVAPAIN 3;

ACIDITY; AMINO TERMINAL SEQUENCE; ANTIMALARIAL ACTIVITY; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SUBSTRATE; ERYTHROCYTE; ESCHERICHIA COLI; GENE IDENTIFICATION; GENETIC CODE; HUMAN; HUMAN CELL; HYDROLYSIS; MOLECULAR CLONING; PLASMODIUM VIVAX; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY;

AMINO ACID SEQUENCE; ANIMALS; ANTIMALARIALS; CLONING, MOLECULAR; CYSTEINE ENDOPEPTIDASES; ERYTHROCYTE MEMBRANE; HEMOGLOBINS; HYDROLYSIS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PLASMODIUM VIVAX; PROTEASE INHIBITORS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PROTOZOA;

EID: 1642292453     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031487     Document Type: Article

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