Trypanosoma brucei: Killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-Phe-Ala-CHN2

Experimental Parasitology

Volumn 91, Issue 4, 1999, Pages 327-333

  Scory, Stefan ^c   Caffrey, Conor R ^a   Stierhof, York Dieter ^b   Ruppel, Andreas ^a   Steverding, Dietmar ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MAX PLANCK INST FÜR BIOLOGIE   (Germany)

^c NONE

Author keywords

AMC, 7 amido 4 methylcoumarin; Chemotherapy; CHN2, diazomethyl ketone; Cysteine proteinases (EC 3.4.22. ); DAPI, 4,6 diamidino 2 phenylindole; Peptidyl diazomethyl ketone; Trypanosoma brucei; Z, benzyloxycarbonyl

Indexed keywords

CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; PHENYLALANYLALANYL DIAZOMETHYL KETONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PARASITEMIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRYPANOSOMA BRUCEI; TRYPANOSOMIASIS;

EID: 0032773796     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.1998.4381     Document Type: Article

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