메뉴 건너뛰기




Volumn 25, Issue 18, 2006, Pages 3049-3080

Advances in statistical human genetics over the last 25 years

Author keywords

Genetic association analysis; Genetic linkage analysis; Genetic segregation analysis

Indexed keywords

DNA;

EID: 33748607485     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.2650     Document Type: Article
Times cited : (17)

References (244)
  • 1
    • 0019302053 scopus 로고
    • Construction of a genetic linkage map in man using restriction fragment length polymorphisms
    • Botstein D, White RL, Skolnick M, Davis RW. Construction of a genetic linkage map in man using restriction fragment length polymorphisms. American Journal of Human Genetics 1980; 32(3):314-331.
    • (1980) American Journal of Human Genetics , vol.32 , Issue.3 , pp. 314-331
    • Botstein, D.1    White, R.L.2    Skolnick, M.3    Davis, R.W.4
  • 2
    • 0022372670 scopus 로고
    • Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia
    • Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich HA, Arnheim N. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 1985; 230(4732):1350-1354.
    • (1985) Science , vol.230 , Issue.4732 , pp. 1350-1354
    • Saiki, R.K.1    Scharf, S.2    Faloona, F.3    Mullis, K.B.4    Horn, G.T.5    Erlich, H.A.6    Arnheim, N.7
  • 4
    • 0026727252 scopus 로고
    • Specific enzymatic amplification of DNA in vitro: The polymerase chain reaction. 1986
    • Mullis K, Faloona F, Scharf S, Saiki R, Horn G, Erlich H. Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction. 1986. Biotechnology 1992; 24:17-27.
    • (1992) Biotechnology , vol.24 , pp. 17-27
    • Mullis, K.1    Faloona, F.2    Scharf, S.3    Saiki, R.4    Horn, G.5    Erlich, H.6
  • 5
    • 0025261742 scopus 로고
    • The unusual origin of the polymerase chain reaction
    • Mullis KB. The unusual origin of the polymerase chain reaction. Scientific American 1990; 262(4):56-65.
    • (1990) Scientific American , vol.262 , Issue.4 , pp. 56-65
    • Mullis, K.B.1
  • 6
    • 0024582686 scopus 로고
    • Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction
    • Weber JL, May PE. Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. American Journal of Human Genetics 1989; 44(3):388-396.
    • (1989) American Journal of Human Genetics , vol.44 , Issue.3 , pp. 388-396
    • Weber, J.L.1    May, P.E.2
  • 7
    • 0035228946 scopus 로고    scopus 로고
    • Genotyping for human whole-genome scans: Past, present, and future
    • Weber JL, Broman KW. Genotyping for human whole-genome scans: past, present, and future. Advances in Genetics 2001; 42:77-96.
    • (2001) Advances in Genetics , vol.42 , pp. 77-96
    • Weber, J.L.1    Broman, K.W.2
  • 10
    • 0141729324 scopus 로고    scopus 로고
    • Robust asymptotic sampling theory for correlations in pedigrees
    • Keen KJ, Elston RC. Robust asymptotic sampling theory for correlations in pedigrees. Statistics in Medicine 2003; 22(20):3229-3247.
    • (2003) Statistics in Medicine , vol.22 , Issue.20 , pp. 3229-3247
    • Keen, K.J.1    Elston, R.C.2
  • 11
    • 0015183542 scopus 로고
    • A general model for the genetic analysis of pedigree data
    • Elston RC, Stewart J. A general model for the genetic analysis of pedigree data. Human Heredity 1971; 21(6):523-542.
    • (1971) Human Heredity , vol.21 , Issue.6 , pp. 523-542
    • Elston, R.C.1    Stewart, J.2
  • 12
    • 0016192958 scopus 로고
    • Analysis of family resemblance. 3. Complex segregation of quantitative traits
    • Morton NE, MacLean CJ. Analysis of family resemblance. 3. Complex segregation of quantitative traits. American Journal of Human Genetics 1974; 26(4):489-503.
    • (1974) American Journal of Human Genetics , vol.26 , Issue.4 , pp. 489-503
    • Morton, N.E.1    MacLean, C.J.2
  • 14
    • 0021281699 scopus 로고
    • On the statistical determination of major gene mechanisms in continuous human traits: Regressive models
    • Bonney GE. On the statistical determination of major gene mechanisms in continuous human traits: regressive models. American Journal of Medical Genetics 1984; 18(4):731-749.
    • (1984) American Journal of Medical Genetics , vol.18 , Issue.4 , pp. 731-749
    • Bonney, G.E.1
  • 15
    • 0022770246 scopus 로고
    • Regressive logistic models for familial disease and other binary traits
    • Bonney GE. Regressive logistic models for familial disease and other binary traits. Biometrics 1986; 42(3):611-625.
    • (1986) Biometrics , vol.42 , Issue.3 , pp. 611-625
    • Bonney, G.E.1
  • 16
    • 0026526717 scopus 로고
    • Compound regressive models for family data
    • Bonney GE. Compound regressive models for family data. Human Heredity 1992; 42(1):28-41.
    • (1992) Human Heredity , vol.42 , Issue.1 , pp. 28-41
    • Bonney, G.E.1
  • 17
    • 0027738047 scopus 로고
    • Effect of ignoring genotype-environment interaction on segregation analysis of quantitative traits
    • Tiret L, Abel L, Rakotovao R. Effect of ignoring genotype-environment interaction on segregation analysis of quantitative traits. Genetic Epidemiology 1993; 10(6):581-586.
    • (1993) Genetic Epidemiology , vol.10 , Issue.6 , pp. 581-586
    • Tiret, L.1    Abel, L.2    Rakotovao, R.3
  • 18
    • 0025123664 scopus 로고
    • Search for faster methods of fitting the regressive models to quantitative traits
    • Demenais FM, Murigande C, Bonney GE. Search for faster methods of fitting the regressive models to quantitative traits. Genetic Epidemiology 1990; 7(5):319-334.
    • (1990) Genetic Epidemiology , vol.7 , Issue.5 , pp. 319-334
    • Demenais, F.M.1    Murigande, C.2    Bonney, G.E.3
  • 19
    • 0002913551 scopus 로고
    • Some recent developments in the theoretical aspects of segregation analysis
    • Majumder PP (ed.). Plenum Publishing: New York
    • Elston RC. Some recent developments in the theoretical aspects of segregation analysis. In Human Population Genetics, Majumder PP (ed.). Plenum Publishing: New York, 1993; 117-137.
    • (1993) Human Population Genetics , pp. 117-137
    • Elston, R.C.1
  • 20
    • 0023550217 scopus 로고
    • Logistic regression for dependent binary observations
    • Bonney GE. Logistic regression for dependent binary observations. Biometrics 1987; 43(4):951-973.
    • (1987) Biometrics , vol.43 , Issue.4 , pp. 951-973
    • Bonney, G.E.1
  • 22
    • 0032513580 scopus 로고    scopus 로고
    • A multivariate logistic model (MLM) for analyzing binary family data
    • Karunaratne PM, Elston RC. A multivariate logistic model (MLM) for analyzing binary family data. American Journal of Medical Genetics 1998; 76(5):428-437.
    • (1998) American Journal of Medical Genetics , vol.76 , Issue.5 , pp. 428-437
    • Karunaratne, P.M.1    Elston, R.C.2
  • 23
    • 0028066555 scopus 로고
    • The finite polygenic mixed model: An alternative formulation for the mixed model of inheritance
    • Fernando RL, Stricker C, Elston RC. The finite polygenic mixed model: an alternative formulation for the mixed model of inheritance. Theoretical and Applied Genetics 1994; 88:573-580.
    • (1994) Theoretical and Applied Genetics , vol.88 , pp. 573-580
    • Fernando, R.L.1    Stricker, C.2    Elston, R.C.3
  • 25
    • 0026668039 scopus 로고
    • A Monte Carlo method for combined segregation and linkage analysis
    • Guo SW, Thompson EA. A Monte Carlo method for combined segregation and linkage analysis. American Journal of Human Genetics 1992; 51(5):1111-1126.
    • (1992) American Journal of Human Genetics , vol.51 , Issue.5 , pp. 1111-1126
    • Guo, S.W.1    Thompson, E.A.2
  • 26
    • 0024490997 scopus 로고
    • Age of onset, age at examination, and other covariates in the analysis of family data
    • Elston RC, George VT. Age of onset, age at examination, and other covariates in the analysis of family data. Genetic Epidemiology 1989; 6(1):217-220.
    • (1989) Genetic Epidemiology , vol.6 , Issue.1 , pp. 217-220
    • Elston, R.C.1    George, V.T.2
  • 27
    • 0022728801 scopus 로고
    • Effects of misspecifying genetic parameters in lod score analysis
    • Clerget-Darpoux F, Bonaïti-Pellié C, Hochez J. Effects of misspecifying genetic parameters in lod score analysis. Biometrics 1986; 42(2):393-399.
    • (1986) Biometrics , vol.42 , Issue.2 , pp. 393-399
    • Clerget-Darpoux, F.1    Bonaïti-Pellié, C.2    Hochez, J.3
  • 28
    • 0027461201 scopus 로고
    • Robustness of the maximum-likelihood (LOD) method for detecting linkage
    • Amos CI, Williamson JA. Robustness of the maximum-likelihood (LOD) method for detecting linkage. American Journal of Human Genetics 1993; 52(1):213-214.
    • (1993) American Journal of Human Genetics , vol.52 , Issue.1 , pp. 213-214
    • Amos, C.I.1    Williamson, J.A.2
  • 29
    • 0025048029 scopus 로고
    • On the asymptotic behavior of the estimate of the recombination fraction under the null hypothesis of no linkage when the model is misspecified
    • Williamson JA, Amos CI. On the asymptotic behavior of the estimate of the recombination fraction under the null hypothesis of no linkage when the model is misspecified. Genetic Epidemiology 1990; 7(5):309-318.
    • (1990) Genetic Epidemiology , vol.7 , Issue.5 , pp. 309-318
    • Williamson, J.A.1    Amos, C.I.2
  • 30
    • 0001395571 scopus 로고
    • Testing for heterogeneity of recombination fraction values in human genetics
    • Smith CAB. Testing for heterogeneity of recombination fraction values in human genetics. Annals of Human Genetics 1963; 27:175-182.
    • (1963) Annals of Human Genetics , vol.27 , pp. 175-182
    • Smith, C.A.B.1
  • 31
    • 0027483312 scopus 로고
    • Distribution of the admixture test for the detection of linkage under heterogeneity
    • Faraway JJ. Distribution of the admixture test for the detection of linkage under heterogeneity. Genetic Epidemiology 1993; 10(1):75-83.
    • (1993) Genetic Epidemiology , vol.10 , Issue.1 , pp. 75-83
    • Faraway, J.J.1
  • 32
    • 0030756227 scopus 로고    scopus 로고
    • Linkage analysis under locus heterogeneity: Behaviour of the A-test in complex analyses
    • Janssen B, Halley D, Sandkuijl L. Linkage analysis under locus heterogeneity: behaviour of the A-test in complex analyses. Human Heredity 1997; 47(4):223-233.
    • (1997) Human Heredity , vol.47 , Issue.4 , pp. 223-233
    • Janssen, B.1    Halley, D.2    Sandkuijl, L.3
  • 33
    • 0035128325 scopus 로고    scopus 로고
    • Problems in the definition, interpretation, and evaluation of genetic heterogeneity
    • Whittemore AS, Halpern J. Problems in the definition, interpretation, and evaluation of genetic heterogeneity. American Journal of Human Genetics 2001; 68(2):457-465.
    • (2001) American Journal of Human Genetics , vol.68 , Issue.2 , pp. 457-465
    • Whittemore, A.S.1    Halpern, J.2
  • 34
    • 0035162422 scopus 로고    scopus 로고
    • The null distribution of the heterogeneity lod score does depend on the assumed genetic model for the trait
    • Huang J, Vieland VJ. The null distribution of the heterogeneity lod score does depend on the assumed genetic model for the trait. Human Heredity 2001; 52(4):217-222.
    • (2001) Human Heredity , vol.52 , Issue.4 , pp. 217-222
    • Huang, J.1    Vieland, V.J.2
  • 35
    • 0036440770 scopus 로고    scopus 로고
    • Evaluating genetic heterogeneity in complex disorders
    • Pal DK, Greenberg DA. Evaluating genetic heterogeneity in complex disorders. Human Heredity 2002; 53(4):216-226.
    • (2002) Human Heredity , vol.53 , Issue.4 , pp. 216-226
    • Pal, D.K.1    Greenberg, D.A.2
  • 36
    • 0036128126 scopus 로고    scopus 로고
    • HLODs, trait models, and ascertainment: Implications of admixture for parameter estimation and linkage detection
    • Vieland VJ, Logue M. HLODs, trait models, and ascertainment: implications of admixture for parameter estimation and linkage detection. Human Heredity 2002; 53(1):23-35.
    • (2002) Human Heredity , vol.53 , Issue.1 , pp. 23-35
    • Vieland, V.J.1    Logue, M.2
  • 37
    • 0036152559 scopus 로고    scopus 로고
    • HLODs remain powerful tools for detection of linkage in the presence of genetic heterogeneity
    • Hodge SE, Vieland VJ, Greenberg DA. HLODs remain powerful tools for detection of linkage in the presence of genetic heterogeneity. American Journal of Human Genetics 2002; 70(2):556-559.
    • (2002) American Journal of Human Genetics , vol.70 , Issue.2 , pp. 556-559
    • Hodge, S.E.1    Vieland, V.J.2    Greenberg, D.A.3
  • 38
    • 0025087330 scopus 로고
    • Power of the linkage test for a heterogeneous disorder due to two independent inherited causes: A simulation study
    • Martinez M, Goldin LR. Power of the linkage test for a heterogeneous disorder due to two independent inherited causes: a simulation study. Genetic Epidemiology 1990; 7(3):219-230.
    • (1990) Genetic Epidemiology , vol.7 , Issue.3 , pp. 219-230
    • Martinez, M.1    Goldin, L.R.2
  • 39
    • 0026329111 scopus 로고
    • Detection of linkage for heterogeneous disorders by using multipoint linkage analysis
    • Martinez M, Goldin LR. Detection of linkage for heterogeneous disorders by using multipoint linkage analysis. American Journal of Human Genetics 1991; 49(6):1300-1305.
    • (1991) American Journal of Human Genetics , vol.49 , Issue.6 , pp. 1300-1305
    • Martinez, M.1    Goldin, L.R.2
  • 40
    • 0026503912 scopus 로고
    • Effect of heterogeneity and assumed mode of inheritance on lod scores
    • Durner M, Greenberg DA. Effect of heterogeneity and assumed mode of inheritance on lod scores. American Journal of Medical Genetics 1992; 42(3):271-275.
    • (1992) American Journal of Medical Genetics , vol.42 , Issue.3 , pp. 271-275
    • Durner, M.1    Greenberg, D.A.2
  • 41
    • 0026664045 scopus 로고
    • Detection of linkage under heterogeneity: Comparison of the two-locus vs. admixture models
    • Goldin LR. Detection of linkage under heterogeneity: comparison of the two-locus vs. admixture models. Genetic Epidemiology 1992; 9(1):61-66.
    • (1992) Genetic Epidemiology , vol.9 , Issue.1 , pp. 61-66
    • Goldin, L.R.1
  • 44
  • 45
    • 0033365403 scopus 로고    scopus 로고
    • An optimal algorithm for automatic genotype elimination
    • O'Connell JR, Weeks DE. An optimal algorithm for automatic genotype elimination. American Journal of Human Genetics 1999; 65(6):1733-1740.
    • (1999) American Journal of Human Genetics , vol.65 , Issue.6 , pp. 1733-1740
    • O'Connell, J.R.1    Weeks, D.E.2
  • 46
    • 0028790963 scopus 로고
    • The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-recoding and fuzzy inheritance
    • O'Connell JR, Weeks DE. The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-recoding and fuzzy inheritance. Nature Genetics 1995; 11(4):402-408.
    • (1995) Nature Genetics , vol.11 , Issue.4 , pp. 402-408
    • O'Connell, J.R.1    Weeks, D.E.2
  • 47
    • 0028857541 scopus 로고
    • Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping
    • Kruglyak L, Daly MJ, Lander ES. Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping. American Journal of Human Genetics 1995; 56(2):519-527.
    • (1995) American Journal of Human Genetics , vol.56 , Issue.2 , pp. 519-527
    • Kruglyak, L.1    Daly, M.J.2    Lander, E.S.3
  • 49
    • 0030802544 scopus 로고    scopus 로고
    • A faster and more general hidden Markov model algorithm for multipoint likelihood calculations
    • Idury RM, Elston RC. A faster and more general hidden Markov model algorithm for multipoint likelihood calculations. Human Heredity 1997; 47(4):197-202.
    • (1997) Human Heredity , vol.47 , Issue.4 , pp. 197-202
    • Idury, R.M.1    Elston, R.C.2
  • 50
    • 0031949481 scopus 로고    scopus 로고
    • Faster multipoint linkage analysis using Fourier transforms
    • Kruglyak L, Lander ES. Faster multipoint linkage analysis using Fourier transforms. Journal of Computational Biology 1998; 5(1):1-7.
    • (1998) Journal of Computational Biology , vol.5 , Issue.1 , pp. 1-7
    • Kruglyak, L.1    Lander, E.S.2
  • 51
    • 0038558013 scopus 로고    scopus 로고
    • Exact genetic linkage computations for general pedigrees
    • Fishelson M, Geiger D. Exact genetic linkage computations for general pedigrees. Bioinformatics 2002; 18(Suppl. 1):SI89-SI98.
    • (2002) Bioinformatics , vol.18 , Issue.SUPPL. 1
    • Fishelson, M.1    Geiger, D.2
  • 52
    • 0036338150 scopus 로고    scopus 로고
    • Merlin-rapid analysis of dense genetic maps using sparse gene flow trees
    • Abecasis GR, Cherny SS, Cookson WO, Cardon LR. Merlin-rapid analysis of dense genetic maps using sparse gene flow trees. Nature Genetics 2002; 30(1):97-101.
    • (2002) Nature Genetics , vol.30 , Issue.1 , pp. 97-101
    • Abecasis, G.R.1    Cherny, S.S.2    Cookson, W.O.3    Cardon, L.R.4
  • 54
    • 2542539742 scopus 로고
    • The Gibbs sampler on extended pedigrees: Monte Carlo methods for the genetic analysis of complex traits
    • Department of Statistics, University of Washington, Seattle, Washington
    • Thompson EA, Wijsman EM. The Gibbs sampler on extended pedigrees: Monte Carlo methods for the genetic analysis of complex traits. Technical Report, 193, Department of Statistics, University of Washington, Seattle, Washington, 1990.
    • (1990) Technical Report, 193
    • Thompson, E.A.1    Wijsman, E.M.2
  • 55
    • 0026329112 scopus 로고
    • A random walk method for computing genetic location scores
    • Lange K, Sobel E. A random walk method for computing genetic location scores. American Journal of Human Genetics 1991; 49(6):1320-1334.
    • (1991) American Journal of Human Genetics , vol.49 , Issue.6 , pp. 1320-1334
    • Lange, K.1    Sobel, E.2
  • 56
    • 0026528757 scopus 로고
    • A Gibbs sampling approach to linkage analysis
    • Thomas DC, Cortessis V. A Gibbs sampling approach to linkage analysis. Human Heredity 1992; 42(1):63-76.
    • (1992) Human Heredity , vol.42 , Issue.1 , pp. 63-76
    • Thomas, D.C.1    Cortessis, V.2
  • 58
    • 0027205090 scopus 로고
    • On the irreducibility of a Markov chain defined on a space of genotype configurations by a sampling scheme
    • Sheehan N, Thomas A. On the irreducibility of a Markov chain defined on a space of genotype configurations by a sampling scheme. Biometrics 1993; 49(1):163-175.
    • (1993) Biometrics , vol.49 , Issue.1 , pp. 163-175
    • Sheehan, N.1    Thomas, A.2
  • 59
    • 2542593163 scopus 로고    scopus 로고
    • Multipoint linkage analyses for disease mapping in extended pedigrees: A Markov Monte Carlo approach
    • George AW, Thompson EA. Multipoint linkage analyses for disease mapping in extended pedigrees: a Markov Monte Carlo approach. Statistical Science 2003; 18:515-531.
    • (2003) Statistical Science , vol.18 , pp. 515-531
    • George, A.W.1    Thompson, E.A.2
  • 60
    • 0028346398 scopus 로고
    • Monte Carlo estimation of mixed models for large complex pedigrees
    • Guo SW, Thompson EA. Monte Carlo estimation of mixed models for large complex pedigrees. Biometrics 1994; 50(2):417-432.
    • (1994) Biometrics , vol.50 , Issue.2 , pp. 417-432
    • Guo, S.W.1    Thompson, E.A.2
  • 61
    • 0027996281 scopus 로고
    • An algorithm for Monte Carlo estimation of genotype probabilities on complex pedigrees
    • Lin S, Thompson EA, Wijsman EM. An algorithm for Monte Carlo estimation of genotype probabilities on complex pedigrees. Annals of Human Genetics 1994; 58(Pt 4):343-357.
    • (1994) Annals of Human Genetics , vol.58 , Issue.PART 4 , pp. 343-357
    • Lin, S.1    Thompson, E.A.2    Wijsman, E.M.3
  • 62
    • 0027506172 scopus 로고
    • A generalized estimating equations approach to fitting major gene models in segregation analysis of continuous phenotypes
    • Lee H, Stram DO, Thomas DC. A generalized estimating equations approach to fitting major gene models in segregation analysis of continuous phenotypes. Genetic Epidemiology 1993; 10(1):61-74.
    • (1993) Genetic Epidemiology , vol.10 , Issue.1 , pp. 61-74
    • Lee, H.1    Stram, D.O.2    Thomas, D.C.3
  • 63
    • 0027763133 scopus 로고
    • Use of generalized estimating equations in segregation analysis of continuous outcomes
    • Stram DO, Lee H, Thomas DC. Use of generalized estimating equations in segregation analysis of continuous outcomes. Genetic Epidemiology 1993; 10(6):575-579.
    • (1993) Genetic Epidemiology , vol.10 , Issue.6 , pp. 575-579
    • Stram, D.O.1    Lee, H.2    Thomas, D.C.3
  • 64
    • 0028627763 scopus 로고
    • Segregation analysis of case-control data using generalized estimating equations
    • Whittemore AS, Gong G. Segregation analysis of case-control data using generalized estimating equations. Biometrics 1994; 50(4):1073-1087.
    • (1994) Biometrics , vol.50 , Issue.4 , pp. 1073-1087
    • Whittemore, A.S.1    Gong, G.2
  • 65
    • 0028066158 scopus 로고
    • Segregation analysis of human pedigrees using estimating equations
    • Zhao LP. Segregation analysis of human pedigrees using estimating equations. Biometrika 1994; 81:197-209.
    • (1994) Biometrika , vol.81 , pp. 197-209
    • Zhao, L.P.1
  • 66
    • 0029655791 scopus 로고    scopus 로고
    • Segregation analysis of continuous phenotypes by using higher sample moments
    • Lee H, Stram DO. Segregation analysis of continuous phenotypes by using higher sample moments. American Journal of Human Genetics 1996; 58(1):213-224.
    • (1996) American Journal of Human Genetics , vol.58 , Issue.1 , pp. 213-224
    • Lee, H.1    Stram, D.O.2
  • 68
    • 0026529005 scopus 로고
    • Model misspecification and multipoint linkage analysis
    • Risch N, Giuffra L. Model misspecification and multipoint linkage analysis. Human Heredity 1992; 42(1):77-92.
    • (1992) Human Heredity , vol.42 , Issue.1 , pp. 77-92
    • Risch, N.1    Giuffra, L.2
  • 69
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genetics 1995; 11(3):241-247.
    • (1995) Nature Genetics , vol.11 , Issue.3 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 71
    • 33745606737 scopus 로고    scopus 로고
    • Distribution and magnitude of type I error of the model-based multipoint lod score: Implications for multipoint mod score
    • Xing C, Elston RC. Distribution and magnitude of type I error of the model-based multipoint lod score: implications for multipoint mod score. Genetic Epidemiology 2006; 30(5):447-458.
    • (2006) Genetic Epidemiology , vol.30 , Issue.5 , pp. 447-458
    • Xing, C.1    Elston, R.C.2
  • 74
    • 0028029930 scopus 로고
    • Lods, wrods, and mods: The interpretation of lod scores calculated under different models
    • Hodge SE, Elston RC. Lods, wrods, and mods: the interpretation of lod scores calculated under different models. Genetic Epidemiology 1994; 11(4):329-342.
    • (1994) Genetic Epidemiology , vol.11 , Issue.4 , pp. 329-342
    • Hodge, S.E.1    Elston, R.C.2
  • 77
    • 0031892437 scopus 로고    scopus 로고
    • Power, mode of inheritance, and type I error in LOD scores and affecteds-only methods: Reply to Kruglyak
    • Greenberg DA, Hodge SE, Vieland VJ, Spence MA. Power, mode of inheritance, and type I error in LOD scores and affecteds-only methods: reply to Kruglyak. American Journal of Human Genetics 1998; 62(1):202-204.
    • (1998) American Journal of Human Genetics , vol.62 , Issue.1 , pp. 202-204
    • Greenberg, D.A.1    Hodge, S.E.2    Vieland, V.J.3    Spence, M.A.4
  • 78
    • 0031020199 scopus 로고    scopus 로고
    • LOD wars: The affected-sib-pair paradigm strikes back!
    • Farrall M. LOD wars: the affected-sib-pair paradigm strikes back! American Journal of Human Genetics 1997; 60(3):735-738.
    • (1997) American Journal of Human Genetics , vol.60 , Issue.3 , pp. 735-738
    • Farrall, M.1
  • 79
    • 0030879571 scopus 로고    scopus 로고
    • Nonparametric linkage tests are model free
    • Kruglyak L. Nonparametric linkage tests are model free. American Journal of Human Genetics 1997; 61(1):254-255.
    • (1997) American Journal of Human Genetics , vol.61 , Issue.1 , pp. 254-255
    • Kruglyak, L.1
  • 80
    • 0035825198 scopus 로고    scopus 로고
    • Model-free vs. model-based linkage analysis: A false dichotomy?
    • Hodge SE. Model-free vs. model-based linkage analysis: a false dichotomy? American Journal of Medical Genetics 2001; 105(1):62-64.
    • (2001) American Journal of Medical Genetics , vol.105 , Issue.1 , pp. 62-64
    • Hodge, S.E.1
  • 81
    • 0142249937 scopus 로고    scopus 로고
    • How to model a complex trait. 1. General considerations and suggestions
    • Strauch K, Fimmers R, Baur MP, Wienker TF. How to model a complex trait. 1. General considerations and suggestions. Human Heredity 2003; 55(4):202-210.
    • (2003) Human Heredity , vol.55 , Issue.4 , pp. 202-210
    • Strauch, K.1    Fimmers, R.2    Baur, M.P.3    Wienker, T.F.4
  • 82
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC. The investigation of linkage between a quantitative trait and a marker locus. Behavior Genetics 1972; 2(1):3-19.
    • (1972) Behavior Genetics , vol.2 , Issue.1 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 83
    • 0024328661 scopus 로고
    • Robust methods for the detection of genetic linkage for quantitative data from pedigrees
    • Amos CI, Elston RC. Robust methods for the detection of genetic linkage for quantitative data from pedigrees. Genetic Epidemiology 1989; 6(2):349-360.
    • (1989) Genetic Epidemiology , vol.6 , Issue.2 , pp. 349-360
    • Amos, C.I.1    Elston, R.C.2
  • 84
    • 0027191513 scopus 로고
    • Linkage between quantitative trait and marker loci: Methods using all relative pairs
    • Olson JM, Wijsman EM. Linkage between quantitative trait and marker loci: methods using all relative pairs. Genetic Epidemiology 1993; 10(2):87-102.
    • (1993) Genetic Epidemiology , vol.10 , Issue.2 , pp. 87-102
    • Olson, J.M.1    Wijsman, E.M.2
  • 85
    • 0026047218 scopus 로고
    • Linkage analysis of quantitative traits: Increased power by using selected samples
    • Carey G, Williamson J. Linkage analysis of quantitative traits: increased power by using selected samples. American Journal of Human Genetics 1991; 49(4):786-796.
    • (1991) American Journal of Human Genetics , vol.49 , Issue.4 , pp. 786-796
    • Carey, G.1    Williamson, J.2
  • 86
    • 0028071382 scopus 로고
    • The power of interval mapping of quantitative trait loci, using selected sib pairs
    • Cardon LR, Fulker DW. The power of interval mapping of quantitative trait loci, using selected sib pairs. American Journal of Human Genetics 1994; 55(4):825-833.
    • (1994) American Journal of Human Genetics , vol.55 , Issue.4 , pp. 825-833
    • Cardon, L.R.1    Fulker, D.W.2
  • 87
    • 0029001682 scopus 로고
    • Extreme discordant sib pairs for mapping quantitative trait loci in humans
    • Risch N, Zhang H. Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 1995; 268(5217):1584-1589.
    • (1995) Science , vol.268 , Issue.5217 , pp. 1584-1589
    • Risch, N.1    Zhang, H.2
  • 88
    • 0025695910 scopus 로고
    • Extensions to sib-pair linkage tests applicable to disorders characterized by delayed onset
    • Dawson DV, Kaplan EB, Elston RC. Extensions to sib-pair linkage tests applicable to disorders characterized by delayed onset. Genetic Epidemiology 1990; 7(6):453-466.
    • (1990) Genetic Epidemiology , vol.7 , Issue.6 , pp. 453-466
    • Dawson, D.V.1    Kaplan, E.B.2    Elston, R.C.3
  • 89
    • 0030857325 scopus 로고    scopus 로고
    • Linkage of multilocus components of variance to polymorphic markers
    • Tiwari HK, Elston RC. Linkage of multilocus components of variance to polymorphic markers. Annals of Human Genetics 1997; 61(Pt 3):253-261.
    • (1997) Annals of Human Genetics , vol.61 , Issue.PART 3 , pp. 253-261
    • Tiwari, H.K.1    Elston, R.C.2
  • 90
    • 0025170498 scopus 로고
    • A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype
    • Amos CI, Elston RC, Bonney GE, Keats BJ, Berenson GS. A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype. American Journal of Human Genetics 1990; 47(2):247-254.
    • (1990) American Journal of Human Genetics , vol.47 , Issue.2 , pp. 247-254
    • Amos, C.I.1    Elston, R.C.2    Bonney, G.E.3    Keats, B.J.4    Berenson, G.S.5
  • 92
    • 33748609005 scopus 로고    scopus 로고
    • Multivariate linkage analysis
    • Elston RC, Olson JM, Palmer L (eds). Wiley: New York
    • De Andrade M, Amos CI. Multivariate linkage analysis. In Biostatistical Genetics and Genetic Epidemiology, Elston RC, Olson JM, Palmer L (eds). Wiley: New York, 2002; 564-568.
    • (2002) Biostatistical Genetics and Genetic Epidemiology , pp. 564-568
    • De Andrade, M.1    Amos, C.I.2
  • 93
    • 0038755008 scopus 로고    scopus 로고
    • New multivariate test for linkage, with application to pleiotropy: Fuzzy Haseman-Elston
    • Kaabi B, Elston RC. New multivariate test for linkage, with application to pleiotropy: fuzzy Haseman-Elston. Genetic Epidemiology 2003; 24(4):253-264.
    • (2003) Genetic Epidemiology , vol.24 , Issue.4 , pp. 253-264
    • Kaabi, B.1    Elston, R.C.2
  • 94
    • 33748611238 scopus 로고    scopus 로고
    • Regression-based multivariate linkage analysis with an application to blood pressure and body mass index
    • Wang T, Elston RC. Regression-based multivariate linkage analysis with an application to blood pressure and body mass index. Annals of Human Genetics 2006; 70: 1-11.
    • (2006) Annals of Human Genetics , vol.70 , pp. 1-11
    • Wang, T.1    Elston, R.C.2
  • 95
    • 0033794945 scopus 로고    scopus 로고
    • A unified Haseman-Elston method for testing linkage with quantitative traits
    • Xu X, Weiss S, Xu X, Wei LJ. A unified Haseman-Elston method for testing linkage with quantitative traits. American Journal of Human Genetics 2000; 67(4):1025-1028,
    • (2000) American Journal of Human Genetics , vol.67 , Issue.4 , pp. 1025-1028
    • Xu, X.1    Weiss, S.2    Xu, X.3    Wei, L.J.4
  • 96
    • 0035017877 scopus 로고    scopus 로고
    • Weighting improves the 'new Haseman-Elston' method
    • Forrest WF. Weighting improves the 'new Haseman-Elston' method. Human Heredity 2001; 52(1):47-54.
    • (2001) Human Heredity , vol.52 , Issue.1 , pp. 47-54
    • Forrest, W.F.1
  • 97
    • 0041884859 scopus 로고    scopus 로고
    • Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: Weighting sums and differences
    • Shete S, Jacobs KB, Elston RC. Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Human Heredity 2003; 55(2-3):79-85.
    • (2003) Human Heredity , vol.55 , Issue.2-3 , pp. 79-85
    • Shete, S.1    Jacobs, K.B.2    Elston, R.C.3
  • 99
    • 21344445009 scopus 로고    scopus 로고
    • Two-level Haseman-Eiston regression for general pedigree data analysis
    • Wang T, Elston RC. Two-level Haseman-Eiston regression for general pedigree data analysis. Genetic Epidemiology 2005; 29(1):12-22.
    • (2005) Genetic Epidemiology , vol.29 , Issue.1 , pp. 12-22
    • Wang, T.1    Elston, R.C.2
  • 101
    • 2942701949 scopus 로고    scopus 로고
    • A modified revisited Haseman-Elston method to further improve power
    • Wang T, Elston RC. A modified revisited Haseman-Elston method to further improve power. Human Heredity 2004; 57(2):109-116.
    • (2004) Human Heredity , vol.57 , Issue.2 , pp. 109-116
    • Wang, T.1    Elston, R.C.2
  • 102
    • 0037869507 scopus 로고    scopus 로고
    • A test of linkage for complex discrete and continuous traits in nuclear families
    • Tritchler D, Liu Y, Fallah S. A test of linkage for complex discrete and continuous traits in nuclear families. Biometrics 2003; 59(2):382-392.
    • (2003) Biometrics , vol.59 , Issue.2 , pp. 382-392
    • Tritchler, D.1    Liu, Y.2    Fallah, S.3
  • 104
    • 0031054384 scopus 로고    scopus 로고
    • A permutation test for the robust sib-pair linkage method
    • Wan Y, Cohen J, Guerra R. A permutation test for the robust sib-pair linkage method. Annals of Human Genetics 1997; 61(Pt 1):79-87.
    • (1997) Annals of Human Genetics , vol.61 , Issue.PART 1 , pp. 79-87
    • Wan, Y.1    Cohen, J.2    Guerra, R.3
  • 105
    • 0003796752 scopus 로고    scopus 로고
    • 5.2-Statistical Analysis for Genetic Epidemiology
    • S.A.G.E
    • S.A.G.E. 5.2-Statistical Analysis for Genetic Epidemiology. 2006. http:// darwin.ewru.edu/sage
    • (2006)
  • 106
    • 0035751287 scopus 로고    scopus 로고
    • Should we consider gene x environment interaction in the bunt for quantitative trait loci?
    • Gauderman WJ, Morrison JL, Siegmund KD. Should we consider gene x environment interaction in the bunt for quantitative trait loci? Genetic Epidemiology 2001; 21(Suppl. 1):S831-S836.
    • (2001) Genetic Epidemiology , vol.21 , Issue.SUPPL. 1
    • Gauderman, W.J.1    Morrison, J.L.2    Siegmund, K.D.3
  • 107
    • 0042887051 scopus 로고    scopus 로고
    • Regression models for linkage: Issues of traits, covariates, heterogeneity, and interaction
    • Schaid DJ, Olson JM, Gauderman WJ, Elston RC. Regression models for linkage: issues of traits, covariates, heterogeneity, and interaction. Human Heredity 2003; 55(2-3):86-96.
    • (2003) Human Heredity , vol.55 , Issue.2-3 , pp. 86-96
    • Schaid, D.J.1    Olson, J.M.2    Gauderman, W.J.3    Elston, R.C.4
  • 108
    • 0007404418 scopus 로고
    • Conditional probabilities of identity of genes at a locus linked to a marker
    • Chevalet C, Gillois M, Khang JV. Conditional probabilities of identity of genes at a locus linked to a marker. Genetic Selection Evolution 1984; 16:431-444.
    • (1984) Genetic Selection Evolution , vol.16 , pp. 431-444
    • Chevalet, C.1    Gillois, M.2    Khang, J.V.3
  • 109
    • 0025245437 scopus 로고
    • Multipoint analysis of human quantitative genetic variation
    • Goldgar DE. Multipoint analysis of human quantitative genetic variation. American Journal of Human Genetics 1990; 47(6):957-967.
    • (1990) American Journal of Human Genetics , vol.47 , Issue.6 , pp. 957-967
    • Goldgar, D.E.1
  • 110
    • 0028058128 scopus 로고
    • Robust variance-components approach for assessing genetic linkage in pedigrees
    • Amos CI. Robust variance-components approach for assessing genetic linkage in pedigrees. American Journal of Human Genetics 1994; 54(3):535-543.
    • (1994) American Journal of Human Genetics , vol.54 , Issue.3 , pp. 535-543
    • Amos, C.I.1
  • 111
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy L, Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. American Journal of Human Genetics 1998; 62(5):1198-1211.
    • (1998) American Journal of Human Genetics , vol.62 , Issue.5 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2
  • 112
  • 114
    • 0021957675 scopus 로고
    • A comparison of sib-pair linkage tests for disease susceptibility loci
    • Blackwelder WC, Elston RC. A comparison of sib-pair linkage tests for disease susceptibility loci. Genetic Epidemiology 1985; 2(1):85-97.
    • (1985) Genetic Epidemiology , vol.2 , Issue.1 , pp. 85-97
    • Blackwelder, W.C.1    Elston, R.C.2
  • 116
    • 11144330100 scopus 로고    scopus 로고
    • Mathematical assumptions versus biological reality: Myths in affected sib pair linkage analysis
    • Elston RC, Song D, Iyengar SK. Mathematical assumptions versus biological reality: myths in affected sib pair linkage analysis. American Journal of Human Genetics 2005; 76(1):152-156.
    • (2005) American Journal of Human Genetics , vol.76 , Issue.1 , pp. 152-156
    • Elston, R.C.1    Song, D.2    Iyengar, S.K.3
  • 117
    • 0025019555 scopus 로고
    • Linkage strategies for genetically complex traits. I. Multilocus models
    • Riscb N. Linkage strategies for genetically complex traits. I. Multilocus models. American Journal of Human Genetics 1990; 46(2):222-228.
    • (1990) American Journal of Human Genetics , vol.46 , Issue.2 , pp. 222-228
    • Riscb, N.1
  • 118
    • 0025008677 scopus 로고
    • Linkage strategies for genetically complex traits. II. The power of affected relative pairs
    • Risch N. Linkage strategies for genetically complex traits. II. The power of affected relative pairs. American Journal of Human Genetics 1990; 46(2):229-241.
    • (1990) American Journal of Human Genetics , vol.46 , Issue.2 , pp. 229-241
    • Risch, N.1
  • 119
    • 0025020461 scopus 로고
    • Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs
    • Risch N. Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. American Journal of Human Genetics 1990; 46(2):242-253.
    • (1990) American Journal of Human Genetics , vol.46 , Issue.2 , pp. 242-253
    • Risch, N.1
  • 120
    • 0029849936 scopus 로고    scopus 로고
    • Using discordantsib pairs to map loci for quantitative traits with high sibling recurrence risk
    • Rogus JJ, Krowlewski AS. Using discordantsib pairs to map loci for quantitative traits with high sibling recurrence risk. American Journal of Human Genetics 1996; 59:1376-1381.
    • (1996) American Journal of Human Genetics , vol.59 , pp. 1376-1381
    • Rogus, J.J.1    Krowlewski, A.S.2
  • 122
    • 0029041213 scopus 로고
    • Robust multipoint linkage analysis: An extension of the Haseman-Elston method
    • Olson JM. Robust multipoint linkage analysis: an extension of the Haseman-Elston method. Genetic Epidemiology 1995; 12(2):177-193.
    • (1995) Genetic Epidemiology , vol.12 , Issue.2 , pp. 177-193
    • Olson, J.M.1
  • 123
    • 0033361931 scopus 로고    scopus 로고
    • Analysis of affected sib pairs, with covariates - With and without constraints
    • Greenwood CM, Bull SB. Analysis of affected sib pairs, with covariates - with and without constraints. American Journal of Human Genetics 1999; 64(3):871-885.
    • (1999) American Journal of Human Genetics , vol.64 , Issue.3 , pp. 871-885
    • Greenwood, C.M.1    Bull, S.B.2
  • 124
    • 0033365221 scopus 로고    scopus 로고
    • Down-weighting of multiple affected sib pairs leads to biased likelihood-ratio tests, under the assumption of no linkage
    • Greenwood CM, Bull SB. Down-weighting of multiple affected sib pairs leads to biased likelihood-ratio tests, under the assumption of no linkage. American Journal of Human Genetics 1999; 64(4):1248-1252.
    • (1999) American Journal of Human Genetics , vol.64 , Issue.4 , pp. 1248-1252
    • Greenwood, C.M.1    Bull, S.B.2
  • 125
    • 0033365302 scopus 로고    scopus 로고
    • Relationship estimation by Markov-process models in a sib-pair linkage study
    • Olson JM. Relationship estimation by Markov-process models in a sib-pair linkage study. American Journal of Human Genetics 1999; 64(5):1464-1472.
    • (1999) American Journal of Human Genetics , vol.64 , Issue.5 , pp. 1464-1472
    • Olson, J.M.1
  • 127
    • 0027529253 scopus 로고
    • Asymptotic properties of affected-sib-pair linkage analysis
    • Holmans P. Asymptotic properties of affected-sib-pair linkage analysis. American Journal of Human Genetics 1993; 52(2):362-374.
    • (1993) American Journal of Human Genetics , vol.52 , Issue.2 , pp. 362-374
    • Holmans, P.1
  • 128
    • 0028270298 scopus 로고
    • Probability of gene identity by descent: Computation and applications
    • Whittemore AS, Halpern J. Probability of gene identity by descent: computation and applications. Biometrics 1994; 50(1):109-117.
    • (1994) Biometrics , vol.50 , Issue.1 , pp. 109-117
    • Whittemore, A.S.1    Halpern, J.2
  • 129
    • 0030728925 scopus 로고    scopus 로고
    • Allele-sharing models: LOD scores and accurate linkage tests
    • Kong A, Cox NJ. Allele-sharing models: LOD scores and accurate linkage tests. American Journal of Human Genetics 1997; 61(5):1179-1188.
    • (1997) American Journal of Human Genetics , vol.61 , Issue.5 , pp. 1179-1188
    • Kong, A.1    Cox, N.J.2
  • 130
  • 131
    • 30344452170 scopus 로고    scopus 로고
    • Linkage analysis of alcohol dependence using both affected and discordant sib pairs
    • Shih PY, Wang T, Xing C, Sinha M, Song Y, Elston RC. Linkage analysis of alcohol dependence using both affected and discordant sib pairs. BMC Genetics 2005; 6(Suppl. 1):S36.
    • (2005) BMC Genetics , vol.6 , Issue.SUPPL. 1
    • Shih, P.Y.1    Wang, T.2    Xing, C.3    Sinha, M.4    Song, Y.5    Elston, R.C.6
  • 132
    • 8844250042 scopus 로고    scopus 로고
    • Ignoring linkage disequilibrium, among tightly linked markers induces false-positive evidence of linkage for affected sib pair analysis
    • Huang Q, Shete S, Amos CI. Ignoring linkage disequilibrium, among tightly linked markers induces false-positive evidence of linkage for affected sib pair analysis. American Journal of Human Genetics 2004; 75(6):1106-1112.
    • (2004) American Journal of Human Genetics , vol.75 , Issue.6 , pp. 1106-1112
    • Huang, Q.1    Shete, S.2    Amos, C.I.3
  • 134
    • 27744559569 scopus 로고    scopus 로고
    • Multipoint linkage analysis for a very dense set of markers
    • Bacanu SA. Multipoint linkage analysis for a very dense set of markers. Genetic Epidemiology 2005; 29(3):195-203.
    • (2005) Genetic Epidemiology , vol.29 , Issue.3 , pp. 195-203
    • Bacanu, S.A.1
  • 135
    • 0000877874 scopus 로고
    • The detection of autosomal linkage in data which consist of pairs of brothers and sisters of unspecified parentage
    • Penrose LS. The detection of autosomal linkage in data which consist of pairs of brothers and sisters of unspecified parentage. Annals of Eugenics 1935; 6:133-138.
    • (1935) Annals of Eugenics , vol.6 , pp. 133-138
    • Penrose, L.S.1
  • 136
    • 1842309941 scopus 로고
    • Associations between HLA and disease
    • Dausset J, Svejgaard A (eds). Munksgaard: Copenhagen
    • Svejgaard A, Ryder LP. Associations between HLA and disease. In HLA and Disease, Dausset J, Svejgaard A (eds). Munksgaard: Copenhagen, 1977; 46-71.
    • (1977) HLA and Disease , pp. 46-71
    • Svejgaard, A.1    Ryder, L.P.2
  • 137
    • 33645517140 scopus 로고    scopus 로고
    • Likelihood-based inference on haplotype effects in genetic association studies
    • Lin DY, Zeng D. Likelihood-based inference on haplotype effects in genetic association studies. Journal of the American Statistical Association 2006; 101:89-118.
    • (2006) Journal of the American Statistical Association , vol.101 , pp. 89-118
    • Lin, D.Y.1    Zeng, D.2
  • 138
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996; 273(5281): 1516-1517.
    • (1996) Science , vol.273 , Issue.5281 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 139
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • Risch NJ. Searching for genetic determinants in the new millennium. Nature 2000; 405(6788):847-856.
    • (2000) Nature , vol.405 , Issue.6788 , pp. 847-856
    • Risch, N.J.1
  • 140
  • 141
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • Spielman RS, McGinnis RE, Ewens WJ. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). American Journal of Human Genetics 1993; 52(3):506-516.
    • (1993) American Journal of Human Genetics , vol.52 , Issue.3 , pp. 506-516
    • Spielman, R.S.1    McGinnis, R.E.2    Ewens, W.J.3
  • 142
    • 31844432717 scopus 로고    scopus 로고
    • What is the significance of a significant TDT?
    • Ewens WJ, Spielman RS. What is the significance of a significant TDT? Human Heredity 2005; 60(4):206-210.
    • (2005) Human Heredity , vol.60 , Issue.4 , pp. 206-210
    • Ewens, W.J.1    Spielman, R.S.2
  • 143
    • 0028981182 scopus 로고
    • An extended transmission/disequilibrium test (TDT) for multi-allele marker loci
    • Sham PC, Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Annals of Human Genetics 1995; 59:323-336.
    • (1995) Annals of Human Genetics , vol.59 , pp. 323-336
    • Sham, P.C.1    Curtis, D.2
  • 144
    • 0029858544 scopus 로고    scopus 로고
    • The TDT and other family-based tests for linkage disequilibrium and association
    • Spielman RS, Ewens WJ. The TDT and other family-based tests for linkage disequilibrium and association. American Journal of Human Genetics 1996; 59(5):983-989.
    • (1996) American Journal of Human Genetics , vol.59 , Issue.5 , pp. 983-989
    • Spielman, R.S.1    Ewens, W.J.2
  • 145
    • 0028632918 scopus 로고
    • Testing for segregation distortion in the HLA complex
    • Jin K, Speed TP, Klitz W, Thomson G. Testing for segregation distortion in the HLA complex. Biometrics 1994; 50(4):1189-1198.
    • (1994) Biometrics , vol.50 , Issue.4 , pp. 1189-1198
    • Jin, K.1    Speed, T.P.2    Klitz, W.3    Thomson, G.4
  • 146
    • 0029597397 scopus 로고
    • Statistical properties of the allelic and genotypic transmission /disequilibrium test for multiallelic markers
    • Bickeböller H, Clerget-Darpoux F. Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markers. Genetic Epidemiology 1995; 12(6):865-870.
    • (1995) Genetic Epidemiology , vol.12 , Issue.6 , pp. 865-870
    • Bickeböller, H.1    Clerget-Darpoux, F.2
  • 147
    • 0029609590 scopus 로고
    • TDT with covariates and genomic screens with mod scores: Their behavior on simulated data
    • Rice JP, Neuman RJ, Hoshaw SL, Daw EW, Gu C. TDT with covariates and genomic screens with mod scores: their behavior on simulated data. Genetic Epidemiology 1995; 12:659-664.
    • (1995) Genetic Epidemiology , vol.12 , pp. 659-664
    • Rice, J.P.1    Neuman, R.J.2    Hoshaw, S.L.3    Daw, E.W.4    Gu, C.5
  • 148
    • 0029956803 scopus 로고    scopus 로고
    • General score tests for associations of genetic markers with disease using cases and their parents
    • Schaid DJ. General score tests for associations of genetic markers with disease using cases and their parents. Genetic Epidemiology 1996; 13(5):423-449.
    • (1996) Genetic Epidemiology , vol.13 , Issue.5 , pp. 423-449
    • Schaid, D.J.1
  • 149
    • 0031018304 scopus 로고    scopus 로고
    • Power studies for the transmission/disequilibrium tests with multiple alleles
    • Kaplan NL, Martin ER, Weir BS. Power studies for the transmission/ disequilibrium tests with multiple alleles. American Journal of Human Genetics 1997; 60(3):691-702.
    • (1997) American Journal of Human Genetics , vol.60 , Issue.3 , pp. 691-702
    • Kaplan, N.L.1    Martin, E.R.2    Weir, B.S.3
  • 150
    • 0031912715 scopus 로고    scopus 로고
    • A sibship test for linkage in the presence of association: The sib transmission/disequilibrium test
    • Spielman RS, Ewens WJ. A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. American Journal of Human Genetics 1998; 62(2):450-458.
    • (1998) American Journal of Human Genetics , vol.62 , Issue.2 , pp. 450-458
    • Spielman, R.S.1    Ewens, W.J.2
  • 151
    • 0032470875 scopus 로고    scopus 로고
    • A discordant-sibship test for disequilibrium and linkage: No need for parental data
    • Horvath S, Laird NM. A discordant-sibship test for disequilibrium and linkage: no need for parental data. American Journal of Human Genetics 1998; 63(6):1886-1897.
    • (1998) American Journal of Human Genetics , vol.63 , Issue.6 , pp. 1886-1897
    • Horvath, S.1    Laird, N.M.2
  • 152
    • 0031949273 scopus 로고    scopus 로고
    • Genetic association mapping based on discordant sib pairs: The discordant-alleles test
    • Boehnke M, Langefeld CD. Genetic association mapping based on discordant sib pairs: the discordant-alleles test. American Journal of Human Genetics 1998; 62(4):950-961.
    • (1998) American Journal of Human Genetics , vol.62 , Issue.4 , pp. 950-961
    • Boehnke, M.1    Langefeld, C.D.2
  • 153
    • 0032897131 scopus 로고    scopus 로고
    • The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping
    • Teng J, Risch N. The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping. Genome Research 1999; 9(3):234-241.
    • (1999) Genome Research , vol.9 , Issue.3 , pp. 234-241
    • Teng, J.1    Risch, N.2
  • 154
    • 0033364961 scopus 로고    scopus 로고
    • The transmission/disequilibrium test and parental-genotype reconstruction: The reconstruction-combined transmission/disequilibrium test
    • Knapp M. The transmission/disequilibrium test and parental-genotype reconstruction: the reconstruction-combined transmission/disequilibrium test. American Journal of Human Genetics 1999; 64(3):861-870.
    • (1999) American Journal of Human Genetics , vol.64 , Issue.3 , pp. 861-870
    • Knapp, M.1
  • 155
    • 0033168224 scopus 로고    scopus 로고
    • Transmission disequilibrium test (TDT) when only one parent is available: The 1-TDT
    • Sun F, Flanders WD, Yang Q, Khoury MJ. Transmission disequilibrium test (TDT) when only one parent is available: the 1-TDT. American Journal of Epidemiology 1999; 150:97-104.
    • (1999) American Journal of Epidemiology , vol.150 , pp. 97-104
    • Sun, F.1    Flanders, W.D.2    Yang, Q.3    Khoury, M.J.4
  • 156
    • 33646188852 scopus 로고    scopus 로고
    • Family-based designs in the age of large-scale gene-association studies
    • Laird NM, Lange C. Family-based designs in the age of large-scale gene-association studies. Nature Reviews Genetics 2006; 7(5):385-394.
    • (2006) Nature Reviews Genetics , vol.7 , Issue.5 , pp. 385-394
    • Laird, N.M.1    Lange, C.2
  • 157
    • 0035025410 scopus 로고    scopus 로고
    • Transmission/disequilibrium test meets measured haplotype analysis: Family-based association analysis guided by evolution of haplotypes
    • Seltman H, Roeder K, Devlin B. Transmission/disequilibrium test meets measured haplotype analysis: family-based association analysis guided by evolution of haplotypes. American Journal of Human Genetics 2001; 68(5):1250-1263.
    • (2001) American Journal of Human Genetics , vol.68 , Issue.5 , pp. 1250-1263
    • Seltman, H.1    Roeder, K.2    Devlin, B.3
  • 158
    • 0036358945 scopus 로고    scopus 로고
    • On a family-based haplotype pattern mining method for linkage disequilibrium mapping
    • Zhang S, Zhang K, Li J, Zhao H. On a family-based haplotype pattern mining method for linkage disequilibrium mapping. Pacific Symposium on Biocomputing 2002; 100-111.
    • (2002) Pacific Symposium on Biocomputing , pp. 100-111
    • Zhang, S.1    Zhang, K.2    Li, J.3    Zhao, H.4
  • 159
    • 0030996759 scopus 로고    scopus 로고
    • On extending the transmission/disequilibrium test (TDT)
    • Wilson SR. On extending the transmission/disequilibrium test (TDT). Annals of Human Genetics 1997; 61(Pt 2):151-161.
    • (1997) Annals of Human Genetics , vol.61 , Issue.PART 2 , pp. 151-161
    • Wilson, S.R.1
  • 160
    • 0033358595 scopus 로고    scopus 로고
    • Transmission/disequilibrium tests for extended marker haplotypes
    • Clayton D, Jones H. Transmission/disequilibrium tests for extended marker haplotypes. American Journal of Human Genetics 1999; 65(4):1161-1169.
    • (1999) American Journal of Human Genetics , vol.65 , Issue.4 , pp. 1161-1169
    • Clayton, D.1    Jones, H.2
  • 161
  • 162
    • 0033237335 scopus 로고    scopus 로고
    • A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission
    • Clayton D. A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission. American Journal of Human Genetics 1999; 65(4):1170-1177.
    • (1999) American Journal of Human Genetics , vol.65 , Issue.4 , pp. 1170-1177
    • Clayton, D.1
  • 164
    • 0033358548 scopus 로고    scopus 로고
    • Use of unlinked genetic markers to detect population stratification in association studies
    • Pritchard JK, Rosenberg NA. Use of unlinked genetic markers to detect population stratification in association studies. American Journal of Human Genetics 1999; 65(1):220-228.
    • (1999) American Journal of Human Genetics , vol.65 , Issue.1 , pp. 220-228
    • Pritchard, J.K.1    Rosenberg, N.A.2
  • 165
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard JK, Stephens M, Donnelly P. Inference of population structure using multilocus genotype data. Genetics 2000; 155(2):945-959.
    • (2000) Genetics , vol.155 , Issue.2 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 166
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin B, Roeder K. Genomic control for association studies. Biometrics 1999; 55(4):997-1004.
    • (1999) Biometrics , vol.55 , Issue.4 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 167
    • 33646247395 scopus 로고    scopus 로고
    • Centralizing the non-central chi-square: A new method to correct for population stratification in genetic case-control association studies
    • Gorroochurn P, Heiman GA, Hodge SE, Greenberg DA. Centralizing the non-central chi-square: a new method to correct for population stratification in genetic case-control association studies. Genetic Epidemiology 2006; 30(4):277-289.
    • (2006) Genetic Epidemiology , vol.30 , Issue.4 , pp. 277-289
    • Gorroochurn, P.1    Heiman, G.A.2    Hodge, S.E.3    Greenberg, D.A.4
  • 170
    • 0043048571 scopus 로고
    • Sequential tests for the detection of linkage
    • Morton NE. Sequential tests for the detection of linkage. American Journal of Human Genetics 1955; 7(3):277-318.
    • (1955) American Journal of Human Genetics , vol.7 , Issue.3 , pp. 277-318
    • Morton, N.E.1
  • 173
    • 0032948850 scopus 로고    scopus 로고
    • Loss of information due to ambiguous haplotyping of SNPs
    • Hodge SE, Boehnke M, Spence MA. Loss of information due to ambiguous haplotyping of SNPs. Nature Genetics 1999; 21(4):360-361.
    • (1999) Nature Genetics , vol.21 , Issue.4 , pp. 360-361
    • Hodge, S.E.1    Boehnke, M.2    Spence, M.A.3
  • 174
    • 0034934775 scopus 로고    scopus 로고
    • Experimentally-derived haplotypes substantially increase the efficiency of linkage disequilibrium studies
    • Douglas JA, Boehnke M, Gillanders E, Trent JM, Gruber SB. Experimentally-derived haplotypes substantially increase the efficiency of linkage disequilibrium studies. Nature Genetics 2001; 28(4):361-364.
    • (2001) Nature Genetics , vol.28 , Issue.4 , pp. 361-364
    • Douglas, J.A.1    Boehnke, M.2    Gillanders, E.3    Trent, J.M.4    Gruber, S.B.5
  • 175
  • 176
    • 0029372419 scopus 로고
    • HAPLO: A program using the EM algorithm to estimate the frequencies of multi-site haplotypes
    • Hawley ME, Kidd KK. HAPLO: a program using the EM algorithm to estimate the frequencies of multi-site haplotypes. The Journal of Heredity 1995; 86(5):409-411.
    • (1995) The Journal of Heredity , vol.86 , Issue.5 , pp. 409-411
    • Hawley, M.E.1    Kidd, K.K.2
  • 177
    • 0029130796 scopus 로고
    • Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
    • Excoffier L, Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Molecular Biology and Evolution 1995; 12(5):921-927.
    • (1995) Molecular Biology and Evolution , vol.12 , Issue.5 , pp. 921-927
    • Excoffier, L.1    Slatkin, M.2
  • 178
    • 0033794938 scopus 로고    scopus 로고
    • Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data
    • Fallin D, Schork NJ. Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data. American Journal of Human Genetics 2000; 67(4):947-959.
    • (2000) American Journal of Human Genetics , vol.67 , Issue.4 , pp. 947-959
    • Fallin, D.1    Schork, N.J.2
  • 179
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. American Journal of Human Genetics 2001; 68(4):978-989.
    • (2001) American Journal of Human Genetics , vol.68 , Issue.4 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 181
    • 0036844521 scopus 로고    scopus 로고
    • Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms
    • Qin ZS, Niu T, Liu JS. Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms. American Journal of Human Genetics 2002; 71(5):1242-1247.
    • (2002) American Journal of Human Genetics , vol.71 , Issue.5 , pp. 1242-1247
    • Qin, Z.S.1    Niu, T.2    Liu, J.S.3
  • 182
    • 0036138183 scopus 로고    scopus 로고
    • Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms
    • Niu T, Qin ZS, Xu X, Liu JS. Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms. American Journal of Human Genetics 2002; 70(1):157-169.
    • (2002) American Journal of Human Genetics , vol.70 , Issue.1 , pp. 157-169
    • Niu, T.1    Qin, Z.S.2    Xu, X.3    Liu, J.S.4
  • 183
    • 0033358667 scopus 로고    scopus 로고
    • Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping
    • McPeek MS, Strahs A. Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping. American Journal of Human Genetics 1999; 65(3):858-875.
    • (1999) American Journal of Human Genetics , vol.65 , Issue.3 , pp. 858-875
    • McPeek, M.S.1    Strahs, A.2
  • 184
    • 0345269986 scopus 로고    scopus 로고
    • On the identification of disease mutations by the analysis of haplotype similarity and goodness of fit
    • Tzeng JY, Devlin B, Wasserman L, Roeder K. On the identification of disease mutations by the analysis of haplotype similarity and goodness of fit. American Journal of Human Genetics 2003; 72(4):891-902.
    • (2003) American Journal of Human Genetics , vol.72 , Issue.4 , pp. 891-902
    • Tzeng, J.Y.1    Devlin, B.2    Wasserman, L.3    Roeder, K.4
  • 186
    • 28944432280 scopus 로고    scopus 로고
    • Haplotype-based linkage disequilibrium mapping via direct data mining
    • Li J, Jiang T. Haplotype-based linkage disequilibrium mapping via direct data mining. Bioinformatics 2005; 21(24):4384-4393.
    • (2005) Bioinformatics , vol.21 , Issue.24 , pp. 4384-4393
    • Li, J.1    Jiang, T.2
  • 187
    • 0000550189 scopus 로고    scopus 로고
    • A density-based algorithm for discovering clusters in large spatial databases with noise
    • Easter M, Kriegel HP, Sander J, Xu X. A density-based algorithm for discovering clusters in large spatial databases with noise. Proceedings KDD, 1996; 226-231.
    • (1996) Proceedings KDD , pp. 226-231
    • Easter, M.1    Kriegel, H.P.2    Sander, J.3    Xu, X.4
  • 188
  • 192
    • 0031915985 scopus 로고    scopus 로고
    • Incorporating genotypes of relatives into a test of linkage disequilibrium
    • Excoffier L, Slatkin M. Incorporating genotypes of relatives into a test of linkage disequilibrium. American Journal of Human Genetics 1998; 62(1):171-180.
    • (1998) American Journal of Human Genetics , vol.62 , Issue.1 , pp. 171-180
    • Excoffier, L.1    Slatkin, M.2
  • 193
    • 0242691208 scopus 로고    scopus 로고
    • A comparison of Bayesian methods for haplotype reconstruction from population genotype data
    • Stephens M, Donnelly P. A comparison of Bayesian methods for haplotype reconstruction from population genotype data. American Journal of Human Genetics 2003; 73(5):1162-1169.
    • (2003) American Journal of Human Genetics , vol.73 , Issue.5 , pp. 1162-1169
    • Stephens, M.1    Donnelly, P.2
  • 194
    • 0036374329 scopus 로고    scopus 로고
    • Haplotyping as perfect phylogeny: Conceptual framework and efficient solutions
    • Washington, DC, April
    • Gusfield D. Haplotyping as perfect phylogeny: conceptual framework and efficient solutions. Proceedings Research in Computational MolecularBiology (RECOMB '02), Washington, DC, April 2002; 166-175.
    • (2002) Proceedings Research in Computational MolecularBiology (RECOMB '02) , pp. 166-175
    • Gusfield, D.1
  • 195
    • 0037223678 scopus 로고    scopus 로고
    • A suboptimal algorithm for de novo peptide sequencing via tandem mass spectrometry
    • Lu B, Chen T. A suboptimal algorithm for de novo peptide sequencing via tandem mass spectrometry. Journal of Computational Biology 2003; 10(1):1-12.
    • (2003) Journal of Computational Biology , vol.10 , Issue.1 , pp. 1-12
    • Lu, B.1    Chen, T.2
  • 196
    • 0033814569 scopus 로고    scopus 로고
    • Zero-recombinant haplotyping: Applications to fine mapping using SNPs
    • O'Connell JR. Zero-recombinant haplotyping: applications to fine mapping using SNPs. Genetic Epidemiology 2000; 19(Suppl. 1):S64-S70.
    • (2000) Genetic Epidemiology , vol.19 , Issue.SUPPL. 1
    • O'Connell, J.R.1
  • 197
    • 0036097372 scopus 로고    scopus 로고
    • Minimum-recombinant haplotyping in pedigrees
    • Qian D, Beckmann L. Minimum-recombinant haplotyping in pedigrees. American Journal of Human Genetics 2002; 70(6):1434-1445.
    • (2002) American Journal of Human Genetics , vol.70 , Issue.6 , pp. 1434-1445
    • Qian, D.1    Beckmann, L.2
  • 198
    • 0033992554 scopus 로고    scopus 로고
    • Haplotyping in pedigrees via a genetic algorithm
    • Tapadar P, Ghosh S, Majumder PP. Haplotyping in pedigrees via a genetic algorithm. Human Heredity 2000; 50(1):43-56.
    • (2000) Human Heredity , vol.50 , Issue.1 , pp. 43-56
    • Tapadar, P.1    Ghosh, S.2    Majumder, P.P.3
  • 199
    • 0023581971 scopus 로고
    • A deductive method of haplotype analysis in pedigrees
    • Wijsman EM. A deductive method of haplotype analysis in pedigrees. American Journal of Human Genetics 1987; 41(3):356-373.
    • (1987) American Journal of Human Genetics , vol.41 , Issue.3 , pp. 356-373
    • Wijsman, E.M.1
  • 202
    • 0035958749 scopus 로고    scopus 로고
    • Genome research: Map of the human genome 3.0
    • Helmuth L. Genome research: map of the human genome 3.0. Science 2001; 293(5530):583-585.
    • (2001) Science , vol.293 , Issue.5530 , pp. 583-585
    • Helmuth, L.1
  • 206
    • 0000642942 scopus 로고
    • Some methods for strengthening the common chi-squared tests
    • Cochran WG. Some methods for strengthening the common chi-squared tests. Biometrics 1954; 10:417-451.
    • (1954) Biometrics , vol.10 , pp. 417-451
    • Cochran, W.G.1
  • 207
    • 0000937686 scopus 로고
    • Tests for linear trends in proportions and frequencies
    • Armitage P. Tests for linear trends in proportions and frequencies. Biometrics 1955; 11:375-386.
    • (1955) Biometrics , vol.11 , pp. 375-386
    • Armitage, P.1
  • 208
    • 0027367005 scopus 로고
    • Genotype relative risks: Methods for design and analysis of candidate-gene association studies
    • Schaid DJ, Sommer SS. Genotype relative risks: methods for design and analysis of candidate-gene association studies. American Journal of Human Genetics 1993; 53(5):1114-1126.
    • (1993) American Journal of Human Genetics , vol.53 , Issue.5 , pp. 1114-1126
    • Schaid, D.J.1    Sommer, S.S.2
  • 210
    • 0042859846 scopus 로고    scopus 로고
    • Optimal two-stage genotyping in population-based association studies
    • Satagopan JM, Elston RC. Optimal two-stage genotyping in population-based association studies. Genetic Epidemiology 2003; 25(2):149-157.
    • (2003) Genetic Epidemiology , vol.25 , Issue.2 , pp. 149-157
    • Satagopan, J.M.1    Elston, R.C.2
  • 211
    • 31744435871 scopus 로고    scopus 로고
    • Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
    • Skol AD, Scott LJ, Abecasis GR, Boehnke M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nature Genetics 2006; 38(2):209-213.
    • (2006) Nature Genetics , vol.38 , Issue.2 , pp. 209-213
    • Skol, A.D.1    Scott, L.J.2    Abecasis, G.R.3    Boehnke, M.4
  • 212
    • 2642583283 scopus 로고    scopus 로고
    • Mapping complex disease loci in whole-genome association studies
    • Carlson CS, Eberle MA, Kruglyak L, Nickerson DA. Mapping complex disease loci in whole-genome association studies. Nature 2004; 429(6990):446-452.
    • (2004) Nature , vol.429 , Issue.6990 , pp. 446-452
    • Carlson, C.S.1    Eberle, M.A.2    Kruglyak, L.3    Nickerson, D.A.4
  • 213
    • 0035214299 scopus 로고    scopus 로고
    • Trimming, weighting, and grouping SNPs in human case-control association studies
    • Hoh J, Wille A, Ott J. Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Research 2001; 11(12):2115-2119.
    • (2001) Genome Research , vol.11 , Issue.12 , pp. 2115-2119
    • Hoh, J.1    Wille, A.2    Ott, J.3
  • 214
    • 0345689434 scopus 로고    scopus 로고
    • Sum statistics for the joint detection of multiple disease loci in case-control association studies with SNP markers
    • Wille A, Hoh J, Ott J. Sum statistics for the joint detection of multiple disease loci in case-control association studies with SNP markers. Genetic Epidemiology 2003; 25(4):350-359.
    • (2003) Genetic Epidemiology , vol.25 , Issue.4 , pp. 350-359
    • Wille, A.1    Hoh, J.2    Ott, J.3
  • 215
    • 0041707972 scopus 로고    scopus 로고
    • Nonparametric disequilibrium mapping of functional sites using haplotypes of multiple tightly linked single-nucleotide polymorphism markers
    • Cheng R, Ma JZ, Wright FA, Lin S, Gao X, Wang D, Elston RC, Li MD. Nonparametric disequilibrium mapping of functional sites using haplotypes of multiple tightly linked single-nucleotide polymorphism markers. Genetics 2003; 164(3):1175-1187.
    • (2003) Genetics , vol.164 , Issue.3 , pp. 1175-1187
    • Cheng, R.1    Ma, J.Z.2    Wright, F.A.3    Lin, S.4    Gao, X.5    Wang, D.6    Elston, R.C.7    Li, M.D.8
  • 216
    • 13444304428 scopus 로고    scopus 로고
    • Fine mapping functional sites or regions from case-control data using haplotypes of multiple linked SNPs
    • Cheng R, Ma JZ, Elston RC, Li MD. Fine mapping functional sites or regions from case-control data using haplotypes of multiple linked SNPs. Annals of Human Genetics 2005; 69(Pt 1):102-112.
    • (2005) Annals of Human Genetics , vol.69 , Issue.PART 1 , pp. 102-112
    • Cheng, R.1    Ma, J.Z.2    Elston, R.C.3    Li, M.D.4
  • 218
    • 0037226556 scopus 로고    scopus 로고
    • On the use of DNA pooling to estimate haplotype frequencies
    • Wang S, Kidd KK, Zhao H. On the use of DNA pooling to estimate haplotype frequencies. Genetic Epidemiology 2003; 24:74-82.
    • (2003) Genetic Epidemiology , vol.24 , pp. 74-82
    • Wang, S.1    Kidd, K.K.2    Zhao, H.3
  • 219
    • 4444270196 scopus 로고    scopus 로고
    • Genotyping pooled DNA on microarrays: A systematic genome screen of thousands of SNPs in large samples to detect QTLs for complex traits
    • Butcher LM, Meaburn E, Liu L, Femandes C, Hill L, Al-Chalabi A, Plomin R, Schalkwyk L, Craig IW. Genotyping pooled DNA on microarrays: a systematic genome screen of thousands of SNPs in large samples to detect QTLs for complex traits. Behavior Genetics 2004; 34(5):549-555.
    • (2004) Behavior Genetics , vol.34 , Issue.5 , pp. 549-555
    • Butcher, L.M.1    Meaburn, E.2    Liu, L.3    Femandes, C.4    Hill, L.5    Al-Chalabi, A.6    Plomin, R.7    Schalkwyk, L.8    Craig, I.W.9
  • 220
    • 25444451094 scopus 로고    scopus 로고
    • Estimating haplotype frequencies in pooled DNA samples when there is genotyping error
    • Quade SR, Elston RC, Goddard KA. Estimating haplotype frequencies in pooled DNA samples when there is genotyping error. BMC Genetics 2005; 6(1):25.
    • (2005) BMC Genetics , vol.6 , Issue.1 , pp. 25
    • Quade, S.R.1    Elston, R.C.2    Goddard, K.A.3
  • 221
    • 0037226556 scopus 로고    scopus 로고
    • On the use of DNA pooling to estimate haplotype frequencies
    • Wang S, Kidd KK, Zhao H. On the use of DNA pooling to estimate haplotype frequencies. Genetic Epidemiology 2003; 24(1):74-82.
    • (2003) Genetic Epidemiology , vol.24 , Issue.1 , pp. 74-82
    • Wang, S.1    Kidd, K.K.2    Zhao, H.3
  • 222
    • 0037320552 scopus 로고    scopus 로고
    • Estimation of haplotype frequencies, linkage-disequilibrium measures, and combination of haplotype copies in each pool by use of pooled DNA data
    • Ito T, Chiku S, Inoue E, Tomita M, Morisaki T, Morisaki H, Kamatani N. Estimation of haplotype frequencies, linkage-disequilibrium measures, and combination of haplotype copies in each pool by use of pooled DNA data. American Journal of Human Genetics 2003; 72(2):384-398.
    • (2003) American Journal of Human Genetics , vol.72 , Issue.2 , pp. 384-398
    • Ito, T.1    Chiku, S.2    Inoue, E.3    Tomita, M.4    Morisaki, T.5    Morisaki, H.6    Kamatani, N.7
  • 224
    • 0032231375 scopus 로고    scopus 로고
    • Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus
    • Nielsen DM, Ehm MG, Weir BS. Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus. American Journal of Human Genetics 1998; 63(5):1531-1540.
    • (1998) American Journal of Human Genetics , vol.63 , Issue.5 , pp. 1531-1540
    • Nielsen, D.M.1    Ehm, M.G.2    Weir, B.S.3
  • 225
    • 31344435414 scopus 로고    scopus 로고
    • A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies
    • Song K, Elston RC. A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies. Statistics in Medicine 2006; 25(1):105-126.
    • (2006) Statistics in Medicine , vol.25 , Issue.1 , pp. 105-126
    • Song, K.1    Elston, R.C.2
  • 226
    • 15044352388 scopus 로고    scopus 로고
    • Genomic control for association studies under various genetic models
    • Zheng G, Freidlin B, Li Z, Gastwirth JL. Genomic control for association studies under various genetic models. Biometrics 2005; 61(1):186-192.
    • (2005) Biometrics , vol.61 , Issue.1 , pp. 186-192
    • Zheng, G.1    Freidlin, B.2    Li, Z.3    Gastwirth, J.L.4
  • 228
    • 0042744696 scopus 로고    scopus 로고
    • Detecting differentially expressed genes in microarrays using Bayesian model selection
    • Ishwaran H, Rao JS. Detecting differentially expressed genes in microarrays using Bayesian model selection. Journal of the American Statistical Association 2003; 98:438-455.
    • (2003) Journal of the American Statistical Association , vol.98 , pp. 438-455
    • Ishwaran, H.1    Rao, J.S.2
  • 229
    • 33644583716 scopus 로고    scopus 로고
    • BAMarray: Java software for Bayesian analysis of variance for microarray data
    • Ishwaran H, Rao JS, Kogalur UB. BAMarray: java software for Bayesian analysis of variance for microarray data. BMC Bioinformatics 2006; 7(1):59.
    • (2006) BMC Bioinformatics , vol.7 , Issue.1 , pp. 59
    • Ishwaran, H.1    Rao, J.S.2    Kogalur, U.B.3
  • 231
    • 2442688965 scopus 로고    scopus 로고
    • Linkage analysis of a complex disease through use of admixed populations
    • Zhu X, Cooper RS, Elston RC. Linkage analysis of a complex disease through use of admixed populations. American Journal of Human Genetics 2004; 74(6):1136-1153.
    • (2004) American Journal of Human Genetics , vol.74 , Issue.6 , pp. 1136-1153
    • Zhu, X.1    Cooper, R.S.2    Elston, R.C.3
  • 232
    • 0003120985 scopus 로고
    • Populations of hybrid origin as source material for the detection of linkage
    • Rife DC. Populations of hybrid origin as source material for the detection of linkage. American Journal of Human Genetics 1954; 6(1):26-33.
    • (1954) American Journal of Human Genetics , vol.6 , Issue.1 , pp. 26-33
    • Rife, D.C.1
  • 233
    • 0032231299 scopus 로고    scopus 로고
    • Methods of linkage analysis - And the assumptions underlying them
    • [see comment]
    • Elston RC. Methods of linkage analysis - and the assumptions underlying them [see comment]. American Journal of Human Genetics 1998; 63(4):931-934.
    • (1998) American Journal of Human Genetics , vol.63 , Issue.4 , pp. 931-934
    • Elston, R.C.1
  • 235
    • 0032231376 scopus 로고    scopus 로고
    • Bayesian linkage analysis, or: How I leamed to stop worrying and love the posterior probability of linkage
    • Vieland VJ. Bayesian linkage analysis, or: how I leamed to stop worrying and love the posterior probability of linkage. American Journal of Human Genetics 1998; 63(4):947-954.
    • (1998) American Journal of Human Genetics , vol.63 , Issue.4 , pp. 947-954
    • Vieland, V.J.1
  • 236
    • 23844440572 scopus 로고    scopus 로고
    • The posterior probability of linkage allowing for linkage disequilibrium and a new estimate of disequilibrium between a trait and a marker
    • Yang X, Huang J, Logue MW, Vieland VJ. The posterior probability of linkage allowing for linkage disequilibrium and a new estimate of disequilibrium between a trait and a marker. Human Heredity 2005; 59(4):210-219.
    • (2005) Human Heredity , vol.59 , Issue.4 , pp. 210-219
    • Yang, X.1    Huang, J.2    Logue, M.W.3    Vieland, V.J.4
  • 237
    • 33748591490 scopus 로고    scopus 로고
    • Thermometers: Something for statistical geneticists to think about
    • in press
    • Vieland VJ. Thermometers: something for statistical geneticists to think about. Human Heredity 2006, in press.
    • (2006) Human Heredity
    • Vieland, V.J.1
  • 238
    • 0031795349 scopus 로고    scopus 로고
    • Linkage and association
    • Elston RC. Linkage and association. Genetic Epidemiology 1998; 15(6):565-576.
    • (1998) Genetic Epidemiology , vol.15 , Issue.6 , pp. 565-576
    • Elston, R.C.1
  • 239
    • 0742288585 scopus 로고    scopus 로고
    • The complex interplay among factors that influence allelic association
    • Zondervan KT, Cardon LR. The complex interplay among factors that influence allelic association. Nature Reviews. Genetics 2004; 5(2):89-100.
    • (2004) Nature Reviews. Genetics , vol.5 , Issue.2 , pp. 89-100
    • Zondervan, K.T.1    Cardon, L.R.2
  • 241
  • 242
    • 27544504021 scopus 로고    scopus 로고
    • Determinants of the success of whole-genome association testing
    • Clark AG, Boerwinkle E, Hixson J, Sing CF. Determinants of the success of whole-genome association testing. Genome Research 2005; 15(11):1463-1467.
    • (2005) Genome Research , vol.15 , Issue.11 , pp. 1463-1467
    • Clark, A.G.1    Boerwinkle, E.2    Hixson, J.3    Sing, C.F.4
  • 243
    • 1642330931 scopus 로고    scopus 로고
    • Linkage disequilibrium testing when linkage phase is unknown
    • Schaid DJ. Linkage disequilibrium testing when linkage phase is unknown. Genetics 2004; 166(1):505-512.
    • (2004) Genetics , vol.166 , Issue.1 , pp. 505-512
    • Schaid, D.J.1
  • 244
    • 0344033602 scopus 로고    scopus 로고
    • Detecting disease associations due to linkage disequilibrium using haplotype tags: A class of tests and the determinants of statistical power
    • Chapman JM, Cooper JD, Todd JA, Clayton DG. Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power. Human Heredity 2003; 56:18-31.
    • (2003) Human Heredity , vol.56 , pp. 18-31
    • Chapman, J.M.1    Cooper, J.D.2    Todd, J.A.3    Clayton, D.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.