Missing data in haplotype analysis: A study on the MILC method

Annals of Human Genetics

Volumn 66, Issue 1, 2002, Pages 99-108

  Bourgain, C ^a   Genin, E ^a   Ober, C ^b   Clerget Darpoux, F ^a  

^a INSERM   (France)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANALYTIC METHOD; ARTICLE; ASTHMA; CONTROLLED STUDY; DATA ANALYSIS; DISEASE PREDISPOSITION; GENETIC IDENTIFICATION; GENETIC MARKER; GENETIC RISK; GENETIC SCREENING; HAPLOTYPE; HEREDITY; HUMAN; HUMAN GENOME; MULTIFACTORIAL GENETIC DISORDER; PRIORITY JOURNAL; PROGENY; SCORING SYSTEM;

ASTHMA; COMPUTER SIMULATION; FOUNDER EFFECT; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; SOFTWARE;

EID: 0036378557     PISSN: 00034800     EISSN: None     Source Type: Journal    
DOI: 10.1017/S000348000100896X     Document Type: Article

References (15)

1. Bourgain, C., Genin, E., Quesneville, H. & Clerget-Darpoux, F. (2000). Search for multifactorial disease susceptibility genes in founder populations. Ann. Hum. Genet. 64. 255-265.
2. Bourgain, C., Génin. E., Holopainen, P., Mustalahti, K., Mäki. M., Partanen, J. & Clerget-Darpoux. F. (2001). Use of closely related affected individuals for the genetic study of complex diseases in founder populations. Am. J. Hum. Genet. 68, 154-159.
3. Clayton, D. & Jones. H. (1999). Transmission/Disequilibrium Tests for Extended Marker Haplotypes. Am. J. Hum. Genet. 65, 1164-1169.
4. Clayton, D. (1999). A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission. Am. J. Hum. Genet. 65, 1170-1177.
5. Curtis, D. & Sham, P. (1995). A note on the application of the Transmission Disequilibrium test when a parent is missing. Am. J. Hum. Genet. 56, 811-812.
6. Dudbridge, F., Koeleman, B., Todd, J. & Clayton, D. (2000). Unbiased application of the Transmission/disequilibrium test to multilocus haplotypes. Am. J. Hum. Genet. 66, 2009-2012.
7. Gudbjartsson, D. F., Jonasson, K., Frigge, M. & Kong, A. (2000). Allegro, a new computer program for multipoint linkage analysis. Nature. Genet. 25, 12-13.
8. Lander, E. S. & Schork, N. J. (1994). Genetic dissection of complex traits. Science 265, 2037-48.
9. Lazzeroni, L. C. (1998). Linkage disequilibrium and gene mapping: an empirical least-squares approach. Am. J. Hum. Genet. 62, 159-170.
10. Ober, C., Tsalenko, A., Parry, R. & Cox, N. (2000). A second-generation genomewide screen for asthma-susceptibility alleles in a founder population Am. J. Hum. Genet. 67, 1154-1162.
11. Ober, C. and Moffat, M. F. (2000). Contributing factors to the pathobiology: The genetics of asthma. In: The Pathobiology of Asthma: Implications for Therapy. (ed. Wenzel S. Clinics in Chest Medicine, W. B. Saunders Company Philadelphia) pp. 245-261.
12. Quesneville, H. & Anxolabéhère, D. (1997). GENOOM: a simulation package for GENetic Object Oriented Modeling. In the Proceeding of the European Mathematical Genetics Meeting. Ann. Hum. Genet. 61, 543.
13. Steinberg, A. G. et al. (1967). Genetic studies on an inbred human isolate. In Proceedings of the Third International Congress of Human Genetics (eds Crow J. F. & Neel J. V.) pp. 267-289, Baltimore: John Hopkins Press.
14. Toivonen, H., Onkamo, P., Vasko, K., Ollikainen, V., Sevon, P., Mannila, H., Herr, M. & Kere, J. (2000). Data mining applied to linkage disequilibrium mapping. Am. J. Hum. Genet. 67, 133-145.
15. Zhao, H., Zhang, S., Merikangas, K., Trixler, M., Wildenauer, D., Sun, F. & Kidd, K. (2000). Transmission/disequilibrium tests using multiple tightly linked markers. Am. J. Hum. Genet. 67, 936-946.