메뉴 건너뛰기




Volumn 9, Issue 9, 2000, Pages 1291-1301

Evaluation of fine mapping strategies for a multifactorial disease locus: Systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21

Author keywords

[No Author keywords available]

Indexed keywords

DNA MARKER; HLA DQ ANTIGEN; MICROSATELLITE DNA;

EID: 0034702031     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/9.9.1291     Document Type: Article
Times cited : (74)

References (37)
  • 1
    • 0025377248 scopus 로고
    • Cutting a gordian knot in the linkage analysis of complex human traits
    • Ott, J. (1990) Cutting a Gordian knot in the linkage analysis of complex human traits. Am. J. Hum. Genet., 46, 219-221.
    • (1990) Am. J. Hum. Genet. , vol.46 , pp. 219-221
    • Ott, J.1
  • 2
    • 0028857007 scopus 로고
    • Polygenic disease: Methods for mapping complex traits
    • Weeks, D.E. and Lathrop, G.M. (1995) Polygenic disease: methods for mapping complex traits. Trends Genet., 11, 513-519.
    • (1995) Trends Genet. , vol.11 , pp. 513-519
    • Weeks, D.E.1    Lathrop, G.M.2
  • 3
    • 0039050424 scopus 로고    scopus 로고
    • Multifactorial diseases: Ancient gene polymorphism at quantitative trait loci and a legacy of survival during our evolution
    • Scriver, C.R., Beaudet, A.L., Sly, W.S., Valle, D.L., Vogelslein, B. and Childs, B. (eds), McGraw-Hill, New York
    • Todd, J.A. (2000) Multifactorial diseases: ancient gene polymorphism at quantitative trait loci and a legacy of survival during our evolution. In Scriver, C.R., Beaudet, A.L., Sly, W.S., Valle, D.L., Vogelslein, B. and Childs, B. (eds), The Metabolic and Molecular Bases of Inherited Disease. McGraw-Hill, New York.
    • (2000) The Metabolic and Molecular Bases of Inherited Disease
    • Todd, J.A.1
  • 4
    • 0029150074 scopus 로고
    • A comparison of linkage disequilibrium measures for fine-scale mapping
    • Devlin, B. and Risen, N. (1995) A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics, 29, 311-322.
    • (1995) Genomics , vol.29 , pp. 311-322
    • Devlin, B.1    Risen, N.2
  • 5
    • 0028952250 scopus 로고
    • High-resolution genetic mapping of complex traits
    • Kruglyak, L. and Lander, E.S. (1995) High-resolution genetic mapping of complex traits. Am. J. Hum. Genet., 56, 1212-1223.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 1212-1223
    • Kruglyak, L.1    Lander, E.S.2
  • 6
    • 0028298036 scopus 로고
    • Maximum-likelihood estimation of gene location by linkage disequilibrium
    • Hill, W.O. and Weir, B.S. (1994) Maximum-likelihood estimation of gene location by linkage disequilibrium. Am. J. Hum. Genet., 54, 705-714.
    • (1994) Am. J. Hum. Genet. , vol.54 , pp. 705-714
    • Hill, W.O.1    Weir, B.S.2
  • 7
    • 0033073397 scopus 로고    scopus 로고
    • Power of association and linkage tests when the disease alleles are unobserved
    • Tu, I.P. and Whittemore, A.S. (1999) Power of association and linkage tests when the disease alleles are unobserved. Am. J. Hum. Genet., 64, 641-649.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 641-649
    • Tu, I.P.1    Whittemore, A.S.2
  • 8
    • 0033071177 scopus 로고    scopus 로고
    • Comparison of the power and accuracy of biallelic and microsatellite markers in population-based gene-mapping methods
    • Xiong, M. and Jin, L. (1999) Comparison of the power and accuracy of biallelic and microsatellite markers in population-based gene-mapping methods. Am. J. Hum. Genet., 64, 629-640.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 629-640
    • Xiong, M.1    Jin, L.2
  • 9
    • 0032827782 scopus 로고    scopus 로고
    • The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits
    • Long, A.D. and Langley, C.H. (1999) The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits. Genome Res., 9, 720-721.
    • (1999) Genome Res. , vol.9 , pp. 720-721
    • Long, A.D.1    Langley, C.H.2
  • 11
    • 0032958427 scopus 로고    scopus 로고
    • Recombination within the human MHC
    • Carrington, M. (1999) Recombination within the human MHC. Immunol. Rev., 167, 245-256.
    • (1999) Immunol. Rev. , vol.167 , pp. 245-256
    • Carrington, M.1
  • 15
    • 0030772982 scopus 로고    scopus 로고
    • Tests for linkage and association in nuclear families
    • Martin, E.R., Kaplan, N.L. and Weir, B.S. (1997) Tests for linkage and association in nuclear families. Am. J. Hum. Genet., 61, 439-448.
    • (1997) Am. J. Hum. Genet. , vol.61 , pp. 439-448
    • Martin, E.R.1    Kaplan, N.L.2    Weir, B.S.3
  • 16
    • 0028981182 scopus 로고
    • An extended transmission/disequilibrium test (TDT) for multi-allele marker loci
    • Sham, P.C. and Curtis, D. (1995) An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann. Hum. Genet., 59, 323-336.
    • (1995) Ann. Hum. Genet. , vol.59 , pp. 323-336
    • Sham, P.C.1    Curtis, D.2
  • 17
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • Spielman, R., McGinnis, R. and Ewens, W. (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am. J. Hum. Genet., 52, 506-516.
    • (1993) Am. J. Hum. Genet. , vol.52 , pp. 506-516
    • Spielman, R.1    McGinnis, R.2    Ewens, W.3
  • 19
    • 0029064537 scopus 로고
    • Mapping disease genes: Family-based association studies
    • Thomson, G. (1995) Mapping disease genes: family-based association studies. Am. J. Hum. Genet, 57, 487-498.
    • (1995) Am. J. Hum. Genet , vol.57 , pp. 487-498
    • Thomson, G.1
  • 20
    • 0033820941 scopus 로고    scopus 로고
    • Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: The conditional extended transmission/disequilibrium test
    • in press
    • Koeleman, B.P.C., Dudbridge, F., Cordell, H.J. and Todd, J.A. (2000) Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium Test. Ann. Hum. Genet., in press.
    • (2000) Ann. Hum. Genet.
    • Koeleman, B.P.C.1    Dudbridge, F.2    Cordell, H.J.3    Todd, J.A.4
  • 22
    • 0032231877 scopus 로고    scopus 로고
    • Comprehensive human genetic maps: Individual and sex-specific variation in recombination
    • Broman, K.W., Murray, J.C., Sheffield, V.C., White, R.L. and Weber, J.L. (1998) Comprehensive human genetic maps: individual and sex-specific variation in recombination. Am. J. Hum. Genet., 63, 861-869.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 861-869
    • Broman, K.W.1    Murray, J.C.2    Sheffield, V.C.3    White, R.L.4    Weber, J.L.5
  • 23
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse, T.J. and Todd, J.A. (1996) Genetic analysis of autoimmune disease. Cell, 85, 311-318.
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 24
    • 0029996490 scopus 로고    scopus 로고
    • Affected-sibpair interval mapping and exclusion for complex genetic traits: Sampling considerations
    • Hauser, E.R., Boehnke, M., Guo, S.W. and Risch, N. (1996) Affected-sibpair interval mapping and exclusion for complex genetic traits: sampling considerations. Genet. Epidemiol., 13, 117-137.
    • (1996) Genet. Epidemiol. , vol.13 , pp. 117-137
    • Hauser, E.R.1    Boehnke, M.2    Guo, S.W.3    Risch, N.4
  • 25
    • 0033237816 scopus 로고    scopus 로고
    • The critical region for Behcet disease in the human major histocompatibility complex is reduced to a 46-kb segment centromeric of HLA-B, by association analysis using refined microsatellite mapping
    • Ota, M., Mizuki, N., Katsuyama, Y., Tamiya, G., Shiina, T., Oka, A., Ando, H., Kimura, M., Goto, K., Ohno, S. and Inoko, H. (1999) The critical region for Behcet disease in the human major histocompatibility complex is reduced to a 46-kb segment centromeric of HLA-B, by association analysis using refined microsatellite mapping. Am. J. Hum. Genet., 64, 1406-1410.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 1406-1410
    • Ota, M.1    Mizuki, N.2    Katsuyama, Y.3    Tamiya, G.4    Shiina, T.5    Oka, A.6    Ando, H.7    Kimura, M.8    Goto, K.9    Ohno, S.10    Inoko, H.11
  • 26
    • 0032697536 scopus 로고    scopus 로고
    • Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111 kb segment telomeric to the HLA-C gene
    • Oka, A., Tamiya, G., Tomizawa, M., Ota, M., Katsuyama, Y., Makino, S., Shiina, T., Yoshitome, M., Iizuka, M., Sasao, Y. et al. (1999) Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111 kb segment telomeric to the HLA-C gene. Hum. Mol. Genet., 8, 2165-2170.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 2165-2170
    • Oka, A.1    Tamiya, G.2    Tomizawa, M.3    Ota, M.4    Katsuyama, Y.5    Makino, S.6    Shiina, T.7    Yoshitome, M.8    Iizuka, M.9    Sasao, Y.10
  • 27
    • 0032822393 scopus 로고    scopus 로고
    • A gene telomeric of the HLA class i region is involved in predisposition to both type 1 diabetes and coeliac disease
    • Lie, B.A., Sollid, L.M., Ascher, H., Ek, J., Akselsen, H.E., Ronningen, K.S., Thorsby, E. and Undlien, D.E. (1999) A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease. Tissue Antigens, 54, 162-168.
    • (1999) Tissue Antigens , vol.54 , pp. 162-168
    • Lie, B.A.1    Sollid, L.M.2    Ascher, H.3    Ek, J.4    Akselsen, H.E.5    Ronningen, K.S.6    Thorsby, E.7    Undlien, D.E.8
  • 28
    • 6844241972 scopus 로고    scopus 로고
    • Transmission of haplotypes of microsatellite markers rather than single marker alleles in the mapping of a putative type 1 diabetes susceptibility gene (IDDM6)
    • Merriman, T., Eaves, I., Twells, R., Merriman, M., Danoy, P., Muxworthy, C., Hunter, K., Cox, R., Cucca, F., Mckinney, P. et al. (1998) Transmission of haplotypes of microsatellite markers rather than single marker alleles in the mapping of a putative type 1 diabetes susceptibility gene (IDDM6). Hum. Mol. Genet., 7, 517-524.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 517-524
    • Merriman, T.1    Eaves, I.2    Twells, R.3    Merriman, M.4    Danoy, P.5    Muxworthy, C.6    Hunter, K.7    Cox, R.8    Cucca, F.9    Mckinney, P.10
  • 30
    • 0025075899 scopus 로고
    • The british diabetic association-warren repository
    • Bain, S.C., Todd, J.A. and Barnett, A.H. (1990) The British Diabetic Association-Warren Repository. Autoimmunity, 7, 83-85.
    • (1990) Autoimmunity , vol.7 , pp. 83-85
    • Bain, S.C.1    Todd, J.A.2    Barnett, A.H.3
  • 31
    • 0031665343 scopus 로고    scopus 로고
    • Microsatellites in the HLA region: 1998 update
    • Foissac, A. and Cambon-Thomsen, A. (1998) Microsatellites in the HLA region: 1998 update. Tissue Antigens, 52, 318-352.
    • (1998) Tissue Antigens , vol.52 , pp. 318-352
    • Foissac, A.1    Cambon-Thomsen, A.2
  • 32
    • 0031030506 scopus 로고    scopus 로고
    • Mapping of 10 novel microsatellites in the MHC class III region: Application to the study of autoimmune disease
    • Hsieh, S.L., March, R.E., Khanna, A., Cross, S.J. and Campbell, R.D. (1997) Mapping of 10 novel microsatellites in the MHC class III region: application to the study of autoimmune disease. J. Rheumatol., 24, 220-222.
    • (1997) J. Rheumatol. , vol.24 , pp. 220-222
    • Hsieh, S.L.1    March, R.E.2    Khanna, A.3    Cross, S.J.4    Campbell, R.D.5
  • 34
    • 0029046177 scopus 로고
    • Complete multipoint sib-pair analysis of qualitative and quantitative traits
    • Kruglyak, L. and Lander, E.S. (1995) Complete multipoint sib-pair analysis of qualitative and quantitative traits. Am. J. Hum. Genet., 57, 439-454.
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 439-454
    • Kruglyak, L.1    Lander, E.S.2
  • 35
    • 0033913132 scopus 로고    scopus 로고
    • Unbiased application of the transmission/disequilibrium test to multilocus haplotypes
    • in press
    • Dudbridge, F., Koeleman, B.P.C., Todd, J.A. and Clayton, D.G. (2000) Unbiased application of the transmission/disequilibrium test to multilocus haplotypes. Am. J. Hum. Genet., in press.
    • (2000) Am. J. Hum. Genet.
    • Dudbridge, F.1    Koeleman, B.P.C.2    Todd, J.A.3    Clayton, D.G.4
  • 36
    • 0027151876 scopus 로고
    • Highly informative typing of the human TNF locus using six adjacent polymorphic markers
    • Udalova, I.A., Nedospasov, S.A., Webb, G.C., Chaplin, D.D. and Turetskaya, R.L. (1993) Highly informative typing of the human TNF locus using six adjacent polymorphic markers. Genomics, 16, 180-186.
    • (1993) Genomics , vol.16 , pp. 180-186
    • Udalova, I.A.1    Nedospasov, S.A.2    Webb, G.C.3    Chaplin, D.D.4    Turetskaya, R.L.5
  • 37
    • 0023430504 scopus 로고
    • Gametic disequilibrium measures: Proceed with caution
    • Hedrick, P.W. (1987) Gametic disequilibrium measures: proceed with caution. Genetics, 117, 331-341.
    • (1987) Genetics , vol.117 , pp. 331-341
    • Hedrick, P.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.