메뉴 건너뛰기




Volumn 56, Issue 1-3, 2003, Pages 18-31

Detecting disease associations due to linkage disequilibrium using haplotype tags: A class of tests and the determinants of statistical power

Author keywords

Association studies; htSNPs; Linkage disequilibrium; Multi locus TDT; Power

Indexed keywords

NUCLEOTIDE;

EID: 0344033602     PISSN: 00015652     EISSN: None     Source Type: Journal    
DOI: 10.1159/000073729     Document Type: Conference Paper
Times cited : (357)

References (22)
  • 3
    • 0344091561 scopus 로고    scopus 로고
    • Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans
    • Carlson CS, Eberle MA, Rieder MJ, Smith J D, Kruglyak L, Nickerson DA: Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans. Nat Genet 2003;33:518-21.
    • (2003) Nat Genet , vol.33 , pp. 518-521
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3    Smith, J.D.4    Kruglyak, L.5    Nickerson, D.A.6
  • 4
    • 0034795550 scopus 로고    scopus 로고
    • Intensely punctate meiotic recombination in the class ii region of the major histocompatibility complex
    • Jeffreys AJ, Kauppi L, Neumann R: Intensely punctate meiotic recombination in the class ii region of the major histocompatibility complex. Nat Genet 2001;29:217-222.
    • (2001) Nat Genet , vol.29 , pp. 217-222
    • Jeffreys, A.J.1    Kauppi, L.2    Neumann, R.3
  • 5
    • 0036783307 scopus 로고    scopus 로고
    • Abstract high-resolution patterns of meiotic recombination across the human major histocompatibility complex
    • Cullen M, Perfetto SP, Klitz W, Nelson G, Carrington M: Abstract high-resolution patterns of meiotic recombination across the human major histocompatibility complex. Am J Hum Genet 2002;71:759-776.
    • (2002) Am J Hum Genet , vol.71 , pp. 759-776
    • Cullen, M.1    Perfetto, S.P.2    Klitz, W.3    Nelson, G.4    Carrington, M.5
  • 7
    • 0002509843 scopus 로고    scopus 로고
    • Analysis of population subdivision
    • Balding DJ, Bishop M, Cannings C (eds). Chichester, Wiley
    • Excoffier L: Analysis of population subdivision; in Balding DJ, Bishop M, Cannings C (eds): Handbook of Statistical Genetics. Chichester, Wiley, 2001.
    • (2001) Handbook of Statistical Genetics
    • Excoffier, L.1
  • 8
    • 0043175289 scopus 로고    scopus 로고
    • Choosing haplotype-tagging SNPs based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the multiethnic cohort study
    • Stram DO, Haiman CA, Hirschharn J N, Altshuler D, Kolonel LN, Henderson BE, Pike M C: Choosing haplotype-tagging SNPs based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the multiethnic cohort study. Hum Hered 2003;55:27-36.
    • (2003) Hum Hered , vol.55 , pp. 27-36
    • Stram, D.O.1    Haiman, C.A.2    Hirschharn, J.N.3    Altshuler, D.4    Kolonel, L.N.5    Henderson, B.E.6    Pike, M.C.7
  • 9
    • 0035978779 scopus 로고    scopus 로고
    • Tackling common disease
    • Todd JA: Tackling common disease. Nature 2001;411:537-539.
    • (2001) Nature , vol.411 , pp. 537-539
    • Todd, J.A.1
  • 10
    • 0037386186 scopus 로고    scopus 로고
    • Genome association studies of complex diseases by case-control designs
    • Fan R, Knapp M: Genome association studies of complex diseases by case-control designs. Am J Hum Genet 2003;72:850-868.
    • (2003) Am J Hum Genet , vol.72 , pp. 850-868
    • Fan, R.1    Knapp, M.2
  • 11
    • 0036155283 scopus 로고    scopus 로고
    • Score tests for association between traits and haplotypes when linkage phase is ambiguous
    • Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA: Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 2002; 70:425-434.
    • (2002) Am J Hum Genet , vol.70 , pp. 425-434
    • Schaid, D.J.1    Rowland, C.M.2    Tines, D.E.3    Jacobson, R.M.4    Poland, G.A.5
  • 12
    • 0036284203 scopus 로고    scopus 로고
    • Testing association of statistically inferred haplotypes with discreate and continuous traits in samples of unrelated individuals
    • Zaykin DV, Westfall PH, Young SS, Karnoub MA, Wagner MJ, Ehm MG: Testing association of statistically inferred haplotypes with discreate and continuous traits in samples of unrelated individuals. Hum Hered 2002;53: 79-91.
    • (2002) Hum Hered , vol.53 , pp. 79-91
    • Zaykin, D.V.1    Westfall, P.H.2    Young, S.S.3    Karnoub, M.A.4    Wagner, M.J.5    Ehm, M.G.6
  • 13
    • 0017878954 scopus 로고
    • Logistic disease incidence models and case-control data
    • Prentice RL, Pyke R: Logistic disease incidence models and case-control data. Biometrika 1978;65:153-158.
    • (1978) Biometrika , vol.65 , pp. 153-158
    • Prentice, R.L.1    Pyke, R.2
  • 14
    • 0002629270 scopus 로고
    • Maximum likelihood from incomplete data via the EM algorithm
    • Dempster A, Laird N, Rubin D: Maximum likelihood from incomplete data via the EM algorithm. J R Stat Soc Ser B 1977;39:1-22.
    • (1977) J R Stat Soc Ser B , vol.39 , pp. 1-22
    • Dempster, A.1    Laird, N.2    Rubin, D.3
  • 15
    • 0037311771 scopus 로고    scopus 로고
    • Efficient selective screening of haplotype tag SNPs
    • Ke X, Cardon LR: Efficient selective screening of haplotype tag SNPs. Bioinformatics 2003; 19:287-288.
    • (2003) Bioinformatics , vol.19 , pp. 287-288
    • Ke, X.1    Cardon, L.R.2
  • 16
    • 0037188541 scopus 로고    scopus 로고
    • A dynamic programming algorithm for haplotype block partitioning
    • Zhang K, Deng M, Chen T, Waterman MS, Sun F: A dynamic programming algorithm for haplotype block partitioning. Proc Natl Acad Sci 2002;99:7335-7339.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 7335-7339
    • Zhang, K.1    Deng, M.2    Chen, T.3    Waterman, M.S.4    Sun, F.5
  • 17
    • 0029130796 scopus 로고
    • Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
    • Excoffier L, Slatkin M: Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 1995;12: 921-925.
    • (1995) Mol Biol Evol , vol.12 , pp. 921-925
    • Excoffier, L.1    Slatkin, M.2
  • 18
    • 0036866635 scopus 로고    scopus 로고
    • Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimetal design
    • Barratt BJ, Payne F, Rance HE, Nutland S, Todd JA, Clayton DG: Identification of the sources of error in allele frequency estimations from pooled DNA indicates an optimal experimetal design. Ann Hum Genet 2002;66:393-405.
    • (2002) Ann Hum Genet , vol.66 , pp. 393-405
    • Barratt, B.J.1    Payne, F.2    Rance, H.E.3    Nutland, S.4    Todd, J.A.5    Clayton, D.G.6
  • 19
    • 0003201075 scopus 로고    scopus 로고
    • A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information
    • Rabinowitz D, Laird N: A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered 2000;504:227-233.
    • (2000) Hum Hered , vol.504 , pp. 227-233
    • Rabinowitz, D.1    Laird, N.2
  • 20
  • 21
    • 0001497804 scopus 로고
    • One degree of freedom for non-additivity
    • Tukey JW: One degree of freedom for non-additivity. Biometrics 1949;5:232-242.
    • (1949) Biometrics , vol.5 , pp. 232-242
    • Tukey, J.W.1
  • 22
    • 0001872828 scopus 로고
    • Goodness of link tests for generalized linear models
    • Pregibon D: Goodness of link tests for generalized linear models. App Stat 1980;29:15-24.
    • (1980) App Stat , vol.29 , pp. 15-24
    • Pregibon, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.