B7H1-Ig fusion protein activates the CD4+ IFN-γ receptor+ type 1 T regulatory subset through IFN-γ-secreting Th1 cells

Journal of Immunology

Volumn 177, Issue 6, 2006, Pages 3606-3614

  Ding, Qing ^a   Lu, Liming ^a   Wang, Baolong ^a   Zhou, Yun ^a,b   Jiang, Yang ^a   Zhou, Xiaorong ^a   Xin, Lijun ^a   Jiao, Zhijun ^a   Chou, Kuang Yen ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b E Institutes of Shanghai Universities   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIBODY; CD45 ANTIGEN; CD45RB ANTIGEN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; PROTEIN B7H1; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ALLERGIC ENCEPHALITIS; ANIMAL CELL; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE RELEASE; DEMYELINATION; IMMUNOLOGICAL TOLERANCE; KERATINOCYTE; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SKIN GRAFT; T LYMPHOCYTE SUBPOPULATION; TH1 CELL;

EID: 33748492329     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.6.3606     Document Type: Article

References (57)

1. + regulatory T cells for immunological self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22: 531-562.
2. + suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2: 389-400.
3. Bluestone, J. A., and A. K. Abbas. 2003. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3: 253-257.
4. + and type 1 regulatory T cells. Curr. Top. Microbiol. Immunol. 293: 303-326.
5. + T cells in the control of inflammation. J. Immunol. 171: 5018-5026.
6. Von Herrath, M. G., and L. C. Harrison. 2003. Antigen-induced regulatory T cells in autoimmunity. Nat. Rev. Immunol. 3: 223-232.
7. + T cells and the control of autoimmune disease. Curr. Opin. Immunol. 16: 695-701.
8. + T cells mediate tumor rejection. J. Immunol. 168: 1-4.
9. + T regulatory type 1 response by cyclooxygenase-2-overexpressing glioma. J. Immunol. 173: 4352-4359.
10. + T regulatory 1 cells to suppress antitumor immunity. J. Immunol. 175: 2931-2937.
11. Chattopadhyay, S., N. G. Chakraborty, and B. Mukherji. 2005. Regulatory T cells and tumor immunity. Cancer Immunol. Immunother. 54: 1153-1161.
12. Wood, K. J., and S. Sakaguchi. 2003. Regulatory T cells in transplantation tolerance. Nat. Rev. Immunol. 3: 199-210.
13. Albert, M. H., Y. Liu, C. Anasetti, and X. Z. Yu. 2005. Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation. Eur. J. Immunol. 35: 2598-2607.
14. Akdis, M., J. Verhagen, A. Taylor, F. Karamloo, C. Karagiannidis, R. Crameri, S. Thunberg, G. Deniz, R. Valenta, H. Fiebig, et al. 2004. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J. Exp. Med. 199: 1567-1575.
15. Hawrylowicz, C. M., and A. O'Garra. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. 2005. Nat. Rev. Immunol. 5: 271-283.
16. + T cells depends on allergen concentration, type of allergen and atopy status of the donor. Immunology 116: 103-111.
17. Akbani, P., G. J. Freeman, E. H. Meyer, E. A. Greenfield, T. T. Chang, A. H. Sharpe, G. Berry, R. H. DeKruyff, and D. T. Umtsu. 2002. Antigen specific regulatory T cells develop via the ICOS-ICOS ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med. 8: 1024-1032.
18. Satoguina, J., M. Mempel, J. Larbi, M. Badusche, C. Loliger, O. Adjei, G. Gachelin, B. Fleischer, and A. Hoerauf. 2002. Antigen-specific T regulatory-1 cells are associated with immunosuppression in a chronic helminth infection (onchocerciasis). Microbes Infect. 4: 1291-1300.
19. + T cells in the control of inflammation. J. Immunol. 171: 5018-5026.
20. + regulatory T cells correlates with more rapid parasite growth in human malaria infection. Immunity 23: 287-296.
21. Mills, K. H., and P. McGuirk. 2004. Antigen-specific regulatory T cells: their induction and role in infection. Semin. Immunol. 16: 107-117.
22. Belkaid, Y., and B. T. Rouse. 2005. Natural regulatory T cells in infection disease. Nat. Immunol. 6: 353-360.
23. Battaglia, M., C. Gianfrani, S. Oregon, and M. G. Roncarolo. 2004. IL-10-producing T regulatory type 1 cells and oral tolerance. Ann. NY Acad. Sci. 1029: 142-153.
24. Aluvihare, V. R., M. Kallinkourdis, and G. B. Alexander. 2004. Regulatory T cells mediate tolerance to the fetus. Nat. Immunol. 5: 266-271.
25. Hori, S., T. Nomura., and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061.
26. + T regulatory cells. Nat. Immunol. 4: 337-342.
27. Thompson, C., and F. Powrie. 2004. Regulatory T cells. Curr. Opin. Pharmacol. 4: 408-414.
28. + Tregs: limiting collateral damage. J. Clin. Invest 114: 1209-1217.
29. Roncarolo, M. G., R. Bacchetta, C. Bordignon, S. Narula, and M. K. Levings. 2001. Type 1 T regulatory cells. Immunol. Rev. 182: 68-79.
30. + regulatory T cells. J. Immunol. 172: 5986-5993.
31. Groux, H. 2003. Type 1 T-regulatory cells: their role in the control of immune responses. Transplantation 75: 8S-12S.
32. Wakkach, A., N. Fournier, V. Brun, J. P. Breittmayer, F. Cottrez, and H. Groux. 2003. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18: 605-617.
33. Lundqvist, A., A. Palmborg, M. Pavlenko, J. Levitskaya, and P. Pisa. 2005. Mature dendritic cells induce tumor-specific type 1 regulatory T cells. J. Immunother. 28: 229-235.
34. + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192: 1213-1222.
35. + Tr cells. Blood 105: 1162-1169.
36. Bacchetta, R., C. Sartirana, M. K. Levings, C. Bordignon, S. Narula, and M. G. Roncarolo. 2002. Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines. Eur. J. Immunol. 32: 2237-2245.
37. Levings, M. K., R. Sangregorio, F. Galbiati, S. Squadrone, M. R. de Waal, and M. G. Roncarolo. 2001. IFN-α and IL-10 induce the differentiation of human type 1 T regulatory cells. J. Immunol. 166: 5530-5539.
38. + T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195: 603-616.
39. O'Neill, E. J., E. Sawicka, C. Manlius, M. A. Le, L. R. Brunet, D. M. Kemeny, G. Bowen, G. Rook, and C. Walker. 2004. Natural and induced regulatory T cells. Ann. NY Acad. Sci. 1029: 180-192.
40. Yang, C. C., T. S. Shih, T. A. Chuh, W. S. Hsu, S. Y. Kuo, and Y. F. Chao. 1980. The intermingled transplantation of auto- and homografts in severe burns. Burns 6: 141-144.
41. Yang, C. C., T. S. Shih, and W. S. Wu. 1982. A Chinese concept of treatment of extensive third-degree burns. Plast. Reconstr. Surg. 70: 238-242.
42. Cao, Y., H. Zhou, J. Tao, Z. Zheng, N. Li, B. Shen, T. S. Shih, J. Hong, J. Zhang, and K. Y. Chou. 2003. Keratinocytes induce local tolerance to skin graft by activating interleukin-10-secreting T cells in the context of costimulation molecule B7-H1. Transplantation 75: 1390-1396.
43. Dong, H., G. Zhu, K. Tamada, and L. Chen. 1999. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat. Med. 5: 1365-1369.
44. Freeman, G. J., A. J. Long, Y. Iwai, K. Bourque, T. Chernova, H. Nishimura, L. J. Fitz, N. Malenkovich, T. Okazaki, M. C. Byrne, et al. 2000. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192: 1027-1034.
45. Tamura, H., H. Dong, G. Zhu, G. L. Sica, D. B. Flies, K. Tamada, and L. Chen. 2001. B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function. Blood 97: 1809-1816.
46. Oliver, A. R., G. M. Lyon, and N. H. Ruddle. 2003. Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice. J. Immunol. 171: 462-468.
47. Tompkins, S. M., J. Padilla, M. C. Dal Canto, J. P. Ting, K. L. Van, and S. D. Miller. 2002. De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis. J. Immunol. 168: 4173-4183.
48. + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. 169: 4712-4716.
49. Bruder, D., M. Probst-Kepper, A. M. Westendorf, R. Geffers, S. Beissert, K. Loser, H. von Boehmer, J. Buer, and W. Hansen. 2004. Neuropilin-1: a surface marker of regulatory T cells. Eur. J. Immunol. 34: 623-630.
50. Loetscher, P., M. Uguccioni, L. Bordoli, M. Baggiolini, B. Moser, C. Chizzolini, and J. M. Dayer. 1998. CCR5 is characteristic of Th1 lymphocytes. Nature 391: 344-345.
51. Murphy, K. M., and S. L. Reiner. 2002. The lineage decisions of helper T cells. Nat. Rev. Immunol. 2: 933-944.
52. Sallusto, F., C. R. Mackay, and A. Lanzavecchia. 1997. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277: 2005-2007.
53. Chen, L. 2004. Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity. Nat. Rev. Immunol. 4: 336-347.
54. + T cells in the control of inflammation. J. Immunol. 171: 5018-5026.
55. Asseman, C., S. Mauze, M. W. Leach, R. L. Coffman, and F. Powrie. 1999. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190: 995-1004.
56. - T cells. J. Clin. Invest. 112: 1437-1443.
57. + regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198: 1875-1886.